-
1
-
-
36749022214
-
The DNA damage response: Ten years after
-
Harper,J.W. and Elledge,S.J. (2007) The DNA damage response: ten years after. Mol. Cell, 28, 739-745
-
(2007)
Mol. Cell
, vol.28
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
2
-
-
33751419716
-
Surviving the breakup: The DNA damage checkpoint
-
Harrison,J.C. and Haber,J.E. (2006) Surviving the breakup: the DNA damage checkpoint. Annu. Rev. Genet., 40, 209-235
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 209-235
-
-
Harrison, J.C.1
Haber, J.E.2
-
3
-
-
0037178748
-
Interfaces between the detection, signaling, and repair of DNA damage
-
Rouse,J. and Jackson,S.P. (2002) Interfaces between the detection, signaling, and repair of DNA damage. Science, 297, 547-551
-
(2002)
Science
, vol.297
, pp. 547-551
-
-
Rouse, J.1
Jackson, S.P.2
-
4
-
-
11244280890
-
Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
-
Audebert,M., Salles,B. and Calsou,P. (2004) Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining. J. Biol. Chem., 279, 55117-55126
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 55117-55126
-
-
Audebert, M.1
Salles, B.2
Calsou, P.3
-
5
-
-
80052566950
-
PARP regulates nonhomologous end joining through retention of Ku at doublestrand breaks
-
Couto,C.A., Wang,H.Y., Green,J.C., Kiely,R., Siddaway,R., Borer,C., Pears,C.J. and Lakin,N.D. (2011) PARP regulates nonhomologous end joining through retention of Ku at doublestrand breaks. J. Cell. Biol., 194, 367-375
-
(2011)
J. Cell. Biol.
, vol.194
, pp. 367-375
-
-
Couto, C.A.1
Wang, H.Y.2
Green, J.C.3
Kiely, R.4
Siddaway, R.5
Borer, C.6
Pears, C.J.7
Lakin, N.D.8
-
6
-
-
77950023283
-
PARP inhibition: PARP1 and beyond
-
Rouleau,M., Patel,A., Hendzel,M.J., Kaufmann,S.H. and Poirier,G.G. (2010) PARP inhibition: PARP1 and beyond. Nat. Rev. Cancer, 10, 293-301
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 293-301
-
-
Rouleau, M.1
Patel, A.2
Hendzel, M.J.3
Kaufmann, S.H.4
Poirier, G.G.5
-
7
-
-
70350088548
-
Mechanisms of double-strand break repair in somatic mammalian cells
-
Hartlerode,A.J. and Scully,R. (2009) Mechanisms of double-strand break repair in somatic mammalian cells. Biochem. J., 423, 157-168
-
(2009)
Biochem. J.
, vol.423
, pp. 157-168
-
-
Hartlerode, A.J.1
Scully, R.2
-
8
-
-
62349103878
-
DNA repair in mammalian cells: DNA double-strand break repair: How to fix a broken relationship
-
Pardo,B., Gomez-Gonzalez,B. and Aguilera,A. (2009) DNA repair in mammalian cells: DNA double-strand break repair: how to fix a broken relationship. Cell Mol. Life Sci., 66, 1039-1056
-
(2009)
Cell Mol. Life Sci.
, vol.66
, pp. 1039-1056
-
-
Pardo, B.1
Gomez-Gonzalez, B.2
Aguilera, A.3
-
9
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan,M.E. and Jasin,M. (2010) Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell. Biol., 11, 196-207
-
(2010)
Nat. Rev. Mol. Cell. Biol.
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
10
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber,M.R. (2010) The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem., 79, 181-211
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
11
-
-
77950466186
-
NHEJ and its backup pathways in chromosomal translocations
-
Lieber,M.R. (2010) NHEJ and its backup pathways in chromosomal translocations. Nat. Struct. Mol. Biol., 17, 393-395
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 393-395
-
-
Lieber, M.R.1
-
12
-
-
84934874465
-
Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans
-
Lieber,M.R., Gu,J., Lu,H., Shimazaki,N. and Tsai,A.G. (2010) Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans. Subcell Biochem., 50, 279-296
-
(2010)
Subcell Biochem.
, vol.50
, pp. 279-296
-
-
Lieber, M.R.1
Gu, J.2
Lu, H.3
Shimazaki, N.4
Tsai, A.G.5
-
13
-
-
34249945536
-
DNA double-strand break repair: From mechanistic understanding to cancer treatment
-
Helleday,T., Lo,J., van Gent,D.C. and Engelward,B.P. (2007) DNA double-strand break repair: from mechanistic understanding to cancer treatment. DNA Repair (Amst), 6, 923-935
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 923-935
-
-
Helleday, T.1
Lo, J.2
Van Gent, D.C.3
Engelward, B.P.4
-
14
-
-
4544362838
-
The mechanism of non-homologous end-joining: A synopsis of synapsis
-
Weterings,E. and van Gent,D.C. (2004) The mechanism of non-homologous end-joining: a synopsis of synapsis. DNA Repair (Amst), 3, 1425-1435
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1425-1435
-
-
Weterings, E.1
Van Gent, D.C.2
-
15
-
-
0027397867
-
The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
-
Gottlieb,T.M. and Jackson,S.P. (1993) The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell, 72, 131-142
-
(1993)
Cell
, vol.72
, pp. 131-142
-
-
Gottlieb, T.M.1
Jackson, S.P.2
-
16
-
-
0018787368
-
X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution
-
Bradley,M.O. and Kohn,K.W. (1979) X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Res., 7, 793-804
-
(1979)
Nucleic Acids Res.
, vol.7
, pp. 793-804
-
-
Bradley, M.O.1
Kohn, K.W.2
-
17
-
-
16144367065
-
Out of the shadows and into the light: The emergence of DNA repair
-
Friedberg,E.C. (1995) Out of the shadows and into the light: the emergence of DNA repair. Trends Biochem Sci, 20, 381
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 381
-
-
Friedberg, E.C.1
-
18
-
-
4344685333
-
The PARP superfamily
-
Ame,J.C., Spenlehauer,C. and de Murcia,G. (2004) The PARP superfamily. Bioessays, 26, 882-893
-
(2004)
Bioessays
, vol.26
, pp. 882-893
-
-
Ame, J.C.1
Spenlehauer, C.2
De Murcia, G.3
-
19
-
-
0033198919
-
Poly(adp-ribosyl)ation reactions in the regulation of nuclear functions
-
D'Amours,D., Desnoyers,S., D'Silva,I. and Poirier,G.G. (1999) Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J., 342(Pt.2), 249-268
-
(1999)
Biochem. J.
, vol.342
, Issue.PART .2
, pp. 249-268
-
-
D'amours, D.1
Desnoyers, S.2
D'silva, I.3
Poirier, G.G.4
-
20
-
-
24344454692
-
Poly(ADPribosyl) ation by PARP-1: PAR-laying' NAD+into a nuclear signal
-
Kim,M.Y., Zhang,T. and Kraus,W.L. (2005) Poly(ADPribosyl) ation by PARP-1: PAR-laying' NAD+into a nuclear signal. Genes Dev., 19, 1951-1967
-
(2005)
Genes Dev.
, vol.19
, pp. 1951-1967
-
-
Kim, M.Y.1
Zhang, T.2
Kraus, W.L.3
-
21
-
-
84863415403
-
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair
-
Polo,S.E., Blackford,A.N., Chapman,J.R., Baskcomb,L., Gravel,S., Rusch,A., Thomas,A., Blundred,R., Smith,P., Kzhyshkowska,J. et al. (2012) Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair. Mol. Cell, 45, 505-516
-
(2012)
Mol. Cell
, vol.45
, pp. 505-516
-
-
Polo, S.E.1
Blackford, A.N.2
Chapman, J.R.3
Baskcomb, L.4
Gravel, S.5
Rusch, A.6
Thomas, A.7
Blundred, R.8
Smith, P.9
Kzhyshkowska, J.10
-
22
-
-
0033001635
-
Relative affinities of poly(ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions
-
D'Silva,I., Pelletier,J.D., Lagueux,J., D'Amours,D., Chaudhry,M.A., Weinfeld,M., Lees-Miller,S.P. and Poirier,G.G. (1999) Relative affinities of poly(ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions. Biochim. Biophys. Acta, 1430, 119-126
-
(1999)
Biochim. Biophys. Acta
, vol.1430
, pp. 119-126
-
-
D'silva, I.1
Pelletier, J.D.2
Lagueux, J.3
D'amours, D.4
Chaudhry, M.A.5
Weinfeld, M.6
Lees-Miller, S.P.7
Poirier, G.G.8
-
23
-
-
63149174843
-
Small-molecule drugs mimicking DNA damage: A new strategy for sensitizing tumors to radiotherapy
-
Quanz,M., Berthault,N., Roulin,C., Roy,M., Herbette,A., Agrario,C., Alberti,C., Josserand,V., Coll,J.L., Sastre-Garau,X. et al. (2009) Small-molecule drugs mimicking DNA damage: a new strategy for sensitizing tumors to radiotherapy. Clin. Cancer Res., 15, 1308-1316
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 1308-1316
-
-
Quanz, M.1
Berthault, N.2
Roulin, C.3
Roy, M.4
Herbette, A.5
Agrario, C.6
Alberti, C.7
Josserand, V.8
Coll, J.L.9
Sastre-Garau, X.10
-
24
-
-
67651251435
-
Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response
-
Quanz,M., Chassoux,D., Berthault,N., Agrario,C., Sun,J.S. and Dutreix,M. (2009) Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response. PLoS One, 4, e6298
-
(2009)
PLoS One
, vol.4
-
-
Quanz, M.1
Chassoux, D.2
Berthault, N.3
Agrario, C.4
Sun, J.S.5
Dutreix, M.6
-
26
-
-
48349135615
-
PARP inhibition versus PARP-1 silencing: Different outcomes in terms of single-strand break repair and radiation susceptibility
-
Godon,C., Cordelieres,F.P., Biard,D., Giocanti,N., Megnin-Chanet,F., Hall,J. and Favaudon,V. (2008) PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility. Nucleic Acids Res., 36, 4454-4464
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 4454-4464
-
-
Godon, C.1
Cordelieres, F.P.2
Biard, D.3
Giocanti, N.4
Megnin-Chanet, F.5
Hall, J.6
Favaudon, V.7
-
28
-
-
0142009654
-
A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage
-
El-Khamisy,S.F., Masutani,M., Suzuki,H. and Caldecott,K.W. (2003) A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage. Nucleic Acids Res., 31, 5526-5533
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 5526-5533
-
-
El-Khamisy, S.F.1
Masutani, M.2
Suzuki, H.3
Caldecott, K.W.4
-
29
-
-
0031844311
-
XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage
-
Masson,M., Niedergang,C., Schreiber,V., Muller,S., Menissier-de Murcia,J. and de Murcia,G. (1998) XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage. Mol. Cell. Biol., 18, 3563-3571
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3563-3571
-
-
Masson, M.1
Niedergang, C.2
Schreiber, V.3
Muller, S.4
Menissier-De Murcia, J.5
De Murcia, G.6
-
30
-
-
2342627913
-
XRCC1 co-localizes and physically interacts with PCNA
-
Fan,J., Otterlei,M., Wong,H.K., Tomkinson,A.E. and Wilson,D.M. III. (2004) XRCC1 co-localizes and physically interacts with PCNA. Nucleic Acids Res., 32, 2193-2201
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 2193-2201
-
-
Fan, J.1
Otterlei, M.2
Wong, H.K.3
Tomkinson, A.E.4
Wilson, D.M.5
-
31
-
-
35448976908
-
XRCC1 and PCNA are loading platforms with distinct kinetic properties and different capacities to respond to multiple DNA lesions
-
Mortusewicz,O. and Leonhardt,H. (2007) XRCC1 and PCNA are loading platforms with distinct kinetic properties and different capacities to respond to multiple DNA lesions. BMC Mol. Biol., 8, 81
-
(2007)
BMC Mol. Biol.
, vol.8
, pp. 81
-
-
Mortusewicz, O.1
Leonhardt, H.2
-
32
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer,H., McCabe,N., Lord,C.J., Tutt,A.N., Johnson,D.A., Richardson,T.B., Santarosa,M., Dillon,K.J., Hickson,I., Knights,C. et al. (2005) Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature, 434, 917-921
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
-
33
-
-
43749120045
-
DNA repair deficiency as a therapeutic target in cancer
-
Martin,S.A., Lord,C.J. and Ashworth,A. (2008) DNA repair deficiency as a therapeutic target in cancer. Curr. Opin. Genet. Dev., 18, 80-86
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 80-86
-
-
Martin, S.A.1
Lord, C.J.2
Ashworth, A.3
-
34
-
-
35348821296
-
A backup DNA repair pathway moves to the forefront
-
Nussenzweig,A. and Nussenzweig,M.C. (2007) A backup DNA repair pathway moves to the forefront. Cell, 131, 223-225
-
(2007)
Cell
, vol.131
, pp. 223-225
-
-
Nussenzweig, A.1
Nussenzweig, M.C.2
-
35
-
-
69949173301
-
Backup pathways of NHEJ in cells of higher eukaryotes: Cell cycle dependence
-
Iliakis,G. (2009) Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence. Radiother. Oncol., 92, 310-315
-
(2009)
Radiother. Oncol.
, vol.92
, pp. 310-315
-
-
Iliakis, G.1
-
36
-
-
84861234127
-
Visualization of a DNA-PK/PARP1 complex
-
Spagnolo,L., Barbeau,J., Curtin,N.J., Morris,E.P. and Pearl,L.H. (2012) Visualization of a DNA-PK/PARP1 complex. Nucleic Acids Res., 40, 4168-4177
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 4168-4177
-
-
Spagnolo, L.1
Barbeau, J.2
Curtin, N.J.3
Morris, E.P.4
Pearl, L.H.5
-
37
-
-
83755224388
-
Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
-
Cheng,Q., Barboule,N., Frit,P., Gomez,D., Bombarde,O., Couderc,B., Ren,G.S., Salles,B. and Calsou,P. (2011) Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks. Nucleic Acids Res., 39, 9605-9619
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 9605-9619
-
-
Cheng, Q.1
Barboule, N.2
Frit, P.3
Gomez, D.4
Bombarde, O.5
Couderc, B.6
Ren, G.S.7
Salles, B.8
Calsou, P.9
-
38
-
-
33745867638
-
Poly(ADP-ribose): Novel functions for an old molecule
-
Schreiber,V., Dantzer,F., Ame,J.C. and de Murcia,G. (2006) Poly(ADP-ribose): novel functions for an old molecule. Nat. Rev. Mol. Cell. Biol., 7, 517-528
-
(2006)
Nat. Rev. Mol. Cell. Biol.
, vol.7
, pp. 517-528
-
-
Schreiber, V.1
Dantzer, F.2
Ame, J.C.3
De Murcia, G.4
-
39
-
-
69949184069
-
New functions for an ancient domain
-
Kraus,W.L. (2009) New functions for an ancient domain. Nat. Struct. Mol. Biol., 16, 904-907
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 904-907
-
-
Kraus, W.L.1
-
40
-
-
58749112769
-
Proteomewide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes
-
Gagne,J.P., Isabelle,M., Lo,K.S., Bourassa,S., Hendzel,M.J., Dawson,V.L., Dawson,T.M. and Poirier,G.G. (2008) Proteomewide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Res., 36, 6959-6976
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 6959-6976
-
-
Gagne, J.P.1
Isabelle, M.2
Lo, K.S.3
Bourassa, S.4
Hendzel, M.J.5
Dawson, V.L.6
Dawson, T.M.7
Poirier, G.G.8
-
41
-
-
80054747189
-
Noncovalent protein interaction with poly(ADP-ribose)
-
Malanga,M. and Althaus,F.R. (2011) Noncovalent protein interaction with poly(ADP-ribose). Methods Mol. Biol., 780, 67-82
-
(2011)
Methods Mol. Biol.
, vol.780
, pp. 67-82
-
-
Malanga, M.1
Althaus, F.R.2
-
42
-
-
77950669700
-
Investigation of PARP-1, PARP-2, and PARG interactomes by affinitypurification mass spectrometry
-
Isabelle,M., Moreel,X., Gagne,J.P., Rouleau,M., Ethier,C., Gagne,P., Hendzel,M.J. and Poirier,G.G. (2010) Investigation of PARP-1, PARP-2, and PARG interactomes by affinitypurification mass spectrometry. Proteome Sci., 8, 22
-
(2010)
Proteome Sci.
, vol.8
, pp. 22
-
-
Isabelle, M.1
Moreel, X.2
Gagne, J.P.3
Rouleau, M.4
Ethier, C.5
Gagne, P.6
Hendzel, M.J.7
Poirier, G.G.8
-
43
-
-
80054757506
-
Purification and characterization of poly(ADP-ribosyl)ated DNA replication/repair complexes
-
Simbulan-Rosenthal,C.M., Rosenthal,D.S. and Smulson,M.E. (2011) Purification and characterization of poly(ADP-ribosyl)ated DNA replication/repair complexes. Methods Mol. Biol., 780, 165-190
-
(2011)
Methods Mol. Biol.
, vol.780
, pp. 165-190
-
-
Simbulan-Rosenthal, C.M.1
Rosenthal, D.S.2
Smulson, M.E.3
-
44
-
-
79952747328
-
Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells
-
Patel,A.G., Sarkaria,J.N. and Kaufmann,S.H. (2011) Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells. Proc. Natl Acad. Sci. USA, 108, 3406-3411
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3406-3411
-
-
Patel, A.G.1
Sarkaria, J.N.2
Kaufmann, S.H.3
-
45
-
-
84855773635
-
A snapshot of chemoresistance to PARP inhibitors
-
Chiarugi,A. (2012) A snapshot of chemoresistance to PARP inhibitors. Trends Pharmacol. Sci., 33, 42-48
-
(2012)
Trends Pharmacol. Sci.
, vol.33
, pp. 42-48
-
-
Chiarugi, A.1
-
46
-
-
77953291328
-
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
-
Bouwman,P., Aly,A., Escandell,J.M., Pieterse,M., Bartkova,J., van der Gulden,H., Hiddingh,S., Thanasoula,M., Kulkarni,A., Yang,Q. et al. (2010) 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat. Struct. Mol. Biol., 17, 688-695.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 688-695
-
-
Bouwman, P.1
Aly, A.2
Escandell, J.M.3
Pieterse, M.4
Bartkova, J.5
Van Der Gulden, H.6
Hiddingh, S.7
Thanasoula, M.8
Kulkarni, A.9
Yang, Q.10
|