Genetic variation in responses to dietary restriction - An unbiased tool for hypothesis testing

Experimental Gerontology

Volumn 48, Issue 10, 2013, Pages 1025-1029

  Liao, Chen Yu ^a,b   Johnson, Thomas E ^c   Nelson, James F ^a,b  

^a University of Texas Health Science Center at San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Dietary restriction; Genetics; Lifespan; Mouse; Recombinant inbred

Indexed keywords

INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; SIRTUIN; SOMATOMEDIN C;

AGING; ALLELE; ANIMAL BEHAVIOR; ANIMAL HOUSING; ARTICLE; BODY TEMPERATURE; DIET RESTRICTION; DOMINANCE BEHAVIOR; EVIDENCE BASED MEDICINE; FAT MASS; FEEDING; FERTILITY; GENE INTERACTION; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC MANIPULATION; GENETIC REGULATION; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE; HAIR GROWTH; HOMOZYGOSITY; HUMAN; HYPOTHESIS; LEAN BODY WEIGHT; LIFE EXTENSION; LONGEVITY; MOUSE STRAIN; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; SURVIVAL; UPREGULATION;

ANIMALIA;

DIETARY RESTRICTION; GENETICS; LIFESPAN; MOUSE; RECOMBINANT INBRED;

ANIMALS; DIET; GENETIC VARIATION; LONGEVITY; MICE; MICE, INBRED STRAINS; PHENOTYPE;

EID: 84883460320     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2013.03.010     Document Type: Article

References (38)

1. Bartke A. Impact of reduced insulin-like growth factor-1/insulin signaling on aging in mammals: novel findings. Aging Cell 2008, 7:285-290.
2. Bartke A., Wright J.C., Mattison J.A., Ingram D.K., Miller R.A., Roth G.S. Extending the lifespan of long-lived mice. Nature 2001, 414:412.
3. Bartke A., Masternak M.M., Al-Regaiey K.A., Bonkowski M.S. Effects of dietary restriction on the expression of insulin-signaling-related genes in long-lived mutant mice. Interdisciplinary 2007, 35:69-82.
4. Barzilai N., Gabriely I. The role of fat depletion in the biological benefits of caloric restriction. J. Nutr. 2001, 131:903S-906S.
5. Barzilai N., Gupta G. Revisiting the role of fat mass in the life extension induced by caloric restriction. J. Gerontol. A Biol. Sci. Med. Sci. 1999, 54:B89-B96. (discussion B97-88).
6. Brown-Borg H.M., Borg K.E., Meliska C.J., Bartke A. Dwarf mice and the ageing process. Nature 1996, 384:33.
7. Colman R.J., Anderson R.M., Johnson S.C., Kastman E.K., Kosmatka K.J., Beasley T.M., Allison D.B., Cruzen C., Simmons H.A., Kemnitz J.W., et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 2009, 325:201-204.
8. Fontana L., Partridge L., Longo V.D. Extending healthy life span - from yeast to humans. Science 2010, 328:321-326.
9. Forster M.J., Morris P., Sohal R.S. Genotype and age influence the effect of caloric intake on mortality in mice. FASEB J. 2003, 17:690-692.
10. Garcia A.M., Busuttil R.A., Calder R.B., Dolle M.E.T., Diaz V., McMahan C.A., Bartke A., Nelson J., Reddick R., Vijg J. Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues. Mech. Ageing Dev. 2008, 129:528-533.
11. Haigis M.C., Guarente L.P. Mammalian sirtuins - emerging roles in physiology, aging, and calorie restriction. Genes Dev. 2006, 20:2913-2921.
12. Harper J.M., Leathers C.W., Austad S.N. Does caloric restriction extend life in wild mice?. Aging Cell 2006, 5:441-449.
13. Harrison D.E., Strong R., Sharp Z.D., Nelson J.F., Astle C.M., Flurkey K., Nadon N.L., Wilkinson J.E., Frenkel K., Carter C.S., et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009, 460:392-395.
14. Johnson T.E., Wood W.B. Genetic analysis of life-span in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 1982, 79:6603-6607.
15. Johnson S., Schleit J., Kaeberlein M., Bennett C. Molecular mechanisms underlying genotype-dependent responses to dietary restriction. 65th Annual Meeting of the Gerontological Society of America 2012, 3. (Abstract).
16. Lang D.H., Gerhard G.S., Griffith J.W., Vogler G.P., Vandenbergh D.J., Blizard D.A., Stout J.T., Lakoski J.M., McClearn G.E. Quantitative trait loci (QTL) analysis of longevity in C57BL/6J by DBA/2J (BXD) recombinant inbred mice. Aging Clin. 2010, 22:8-19.
17. Liang H., Masoro E.J., Nelson J.F., Strong R., McMahan C.A., Richardson A. Genetic mouse models of extended lifespan. Exp. Gerontol. 2003, 38:1353-1364.
18. Liao C.-Y., Rikke B.A., Johnson T.E., Diaz V., Nelson J.F. Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell 2010, 9:92-95.
19. Liao C.-Y., Rikke B.A., Johnson T.E., Diaz V., Nelson J.F. No evidence that competition for food underlies lifespan shortening by dietary restriction in multiply housed mice. Aging Cell 2010, 9:450-452.
20. Liao C.Y., Rikke B.A., Johnson T.E., Gelfond J.A., Diaz V., Nelson J.F. Fat maintenance is a predictor of the murine lifespan response to dietary restriction. Aging Cell 2011, 10:629-639.
21. Masoro E.J. Role of sirtuin proteins in life extension by caloric restriction. Mech. Ageing Dev. 2004, 125:591-594.
22. Masoro E.J. Overview of caloric restriction and ageing. Mech. Ageing Dev. 2005, 126:913-922.
23. Mattison J.A., Roth G.S., Beasley T.M., Tilmont E.M., Handy A.M., Herbert R.L., Longo D.L., Allison D.B., Young J.E., Bryant M., et al. Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 2012, 489:318-321.
24. Mattson M.P. Genes and behavior interact to determine mortality in mice when food is scarce and competition fierce. Aging Cell 2010, 9:448-449. (discussion 450-442).
25. McCay C.M., Crowell M.F., Maynard L.A. The effect of retarded growth upon the length of life and upon the ultimate body size. J. Nutr. 1935, 10:63-79.
26. Nakagawa S., Lagisz M., Hector K.L., Spencer H.G. Comparative and meta-analytic insights into life extension via dietary restriction. Aging Cell 2012, 11:401-409.
27. Picard F., Guarente L. Molecular links between aging and adipose tissue. Int. J. Obes. (Lond.) 2005, 29(Suppl. 1):S36-S39.
28. Rikke B.A., Johnson T.E. Physiological genetics of dietary restriction: uncoupling the body temperature and body weight responses. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293:R1522-R1527.
29. Rikke B.A., Liao C.-Y., McQueen M.B., Nelson J.F., Johnson T.E. Genetic dissection of dietary restriction in mice supports the metabolic efficiency model of life extension. Exp. Gerontol. 2010, 45:691-701.
30. Schleit J., Wasko B.M., Kaeberlein M. Yeast as a model to understand the interaction between genotype and the response to calorie restriction. FEBS Lett. 2012, 586:2868-2873.
31. Sohal R.S., Ferguson M., Sohal B.H., Forster M.J. Life span extension in mice by food restriction depends on an energy imbalance. J. Nutr. 2009, 139:533-539.
32. Speakman J.R., Mitchell S.E. Caloric restriction. Mol. Aspects Med. 2011, 32:159-221.
33. Swindell W.R. Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan. Ageing Res. Rev. 2012, 11:254-270.
34. Turturro A., Witt W.W., Lewis S., Hass B.S., Lipman R.D., Hart R.W. Growth curves and survival characteristics of the animals used in the biomarkers of aging program. J. Gerontol. A Biol. Sci. Med. Sci. 1999, 54:B492-B501.
35. Weindruch R., Walford R. The Retardation of Aging and Disease by Dietary Restriction 1988, Charles C Thomas Publisher, Springfield, III.
36. Williams R.W., Bennett B., Lu L., Gu J., DeFries J.C., Carosone-Link P.J., Rikke B.A., Belknap J.K., Johnson T.E. Genetic structure of the LXS panel of recombinant inbred mouse strains: a powerful resource for complex trait analysis. Mamm. Genome 2004, 15:637-647.
37. Yuan R., Tsaih S.-W., Petkova S.B., de Evsikova C.M., Xing S., Marion M.A., Bogue M.A., Mills K.D., Peters L.L., Bult C.J., et al. Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging Cell 2009, 8:277-287.
38. Yuan R., Peters L.L., Paigen B. Mice as a mammalian model for research on the genetics of aging. ILAR J. 2011, 52:4-15.