Phosphorylation-induced Conformational Changes of Cystic Fibrosis Transmembrane Conductance Regulator Monitored by Attenuated Total Reflection-Fourier Transform IR Spectroscopy and Fluorescence Spectroscopy

Journal of Biological Chemistry

Volumn 279, Issue 7, 2004, Pages 5528-5536

  Grimard, Vinciane ^a,c   Li, Canhui ^b   Ramjeesingh, Mohabir ^b   Bear, Christine E ^b   Goormaghtigh, Erik ^a   Ruysschaert, Jean Marie ^a  

^a FREE UNIVERSITY OF BRUSSELS   (Belgium)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; FIBROUS MEMBRANES; FLUORESCENCE; FOURIER TRANSFORM INFRARED SPECTROSCOPY; PROTEINS;

NUCLEOTIDE BINDING DOMAINS; PHOSPHORYLATION;

BIOCHEMISTRY;

CYCLIC AMP DEPENDENT PROTEIN KINASE; NUCLEOTIDE; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRYPTOPHAN;

AQUEOUS SOLUTION; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; FLUORESCENCE SPECTROSCOPY; INFRARED SPECTROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTON TRANSPORT;

ANIMALS; BINDING SITES; CHLORIDES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOSOL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; INSECTS; IONS; KINETICS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SILVER STAINING; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TIME FACTORS;

EID: 1242294450     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M311014200     Document Type: Article

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