Inhibition of endogenous phosphodiesterase 7 promotes oligodendrocyte precursor differentiation and survival

Cellular and Molecular Life Sciences

Volumn 70, Issue 18, 2013, Pages 3449-3462

  Medina Rodriguez E M ^a   Arenzana, F J ^a   Pastor, J ^b   Redondo, M ^c   Palomo, V ^c   Garcia De Sola R ^b   Gil, C ^c   Martinez A ^c   Bribian A ^a,d   De Castro, F ^a  

^a HOSPITAL NACIONAL DE PARAPLÉJICOS   (Spain)

^b HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^c INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Multiple sclerosis; Oligodendrocyte differentiation; PDE7 inhibitors

Indexed keywords

2 METHYL 5 NITROBENZENESULFONIC ACID DIMETHYLAMIDE; CYCLIC AMP; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHODIESTERASE VII; PHOSPHODIESTERASE VII INHIBITOR;

ADULT; ANIMAL CELL; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CELL SURVIVAL; ENZYME INHIBITION; ENZYME METABOLISM; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; OLIGODENDROCYTE PRECURSOR CELL; OLIGODENDROGLIA; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; RAT; REGULATORY MECHANISM;

ADULT; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CEREBRAL CORTEX; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 7; ENZYME INHIBITORS; EPILEPSY; HUMANS; MICE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MULTIPLE SCLEROSIS; OLIGODENDROGLIA; PHENOTYPE; SIGNAL TRANSDUCTION;

MURINAE;

EID: 84883452898     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1340-2     Document Type: Article

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