Chronic alcohol feeding inhibits physiological and molecular parameters of intestinal and renal riboflavin transport

American Journal of Physiology - Cell Physiology

Volumn 305, Issue 5, 2013, Pages

  Subramanian, Veedamali S ^a,b   Subramanya, Sandeep B ^a,b   Ghosal, Abhisek ^a,b   Said, Hamid M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA LONG BEACH HEALTHCARE SYSTEM   (United States)

Author keywords

Intestinal transport; Renal transport; Riboflavin transporter 1; Riboflavin transporter 3

Indexed keywords

HETEROGENEOUS NUCLEAR RNA; MESSENGER RNA; RIBOFLAVIN; RIBOFLAVIN TRANSPORTER 1; RIBOFLAVIN TRANSPORTER 3; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; COLON; CONTROLLED STUDY; INTESTINE ABSORPTION; INTESTINE BRUSH BORDER; KIDNEY TUBULE EPITHELIUM; MALE; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

INTESTINAL TRANSPORT; RENAL TRANSPORT; RIBOFLAVIN TRANSPORTER-1; RIBOFLAVIN TRANSPORTER-3;

ALCOHOL DRINKING; ANIMALS; BIOLOGICAL TRANSPORT; COLON; DIET; ENTEROCYTES; ETHANOL; GENE EXPRESSION REGULATION; HUMANS; INTESTINAL ABSORPTION; INTESTINE, SMALL; KIDNEY; MALE; MEMBRANE TRANSPORT PROTEINS; MICROVILLI; PROTEIN ISOFORMS; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RIBOFLAVIN; TRANSCRIPTION, GENETIC;

EID: 84883428411     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00089.2013     Document Type: Article

References (46)

1. Aydemir F, Jenkitkasemwong S, Gulec S, Knutson MD. Iron loading increase ferroportin heterogeneous nuclear RNA and mRNA levels in murine J774 macrophages. J Nutr 139: 434-438, 2009.
2. Bao HF, Song JZ, Duke BJ, Ma HP, Denson DD. Ethanol stimulates epithelial sodium channels by elevating reactive oxygen species. Am J Physiol Cell Physiol 303: C1129-C1138, 2012.
3. Betz AL, Ren XD, Ennis SR, Hultquist DE. Riboflavin reduces edema in focal cerebral ischemia. Acta Neurochir Suppl (Wien) 60: 314-317, 1994.
4. Bonjour JP. Vitamins and alcoholism. V Riboflavin, VI Niacin, VII Pantothenic acid, and VIII Biotin. Int J Vitam Nutr Res 50: 425-440, 1980.
5. Cooperman JM, Lopez R. Riboflavin. In: Handbook of Vitamins: Nutritional, Biochemical and Clinical Aspects, edited by Machlin LJ. New York, NY: Dekker, 1984, p. 299-327.
6. Elferink CJ, Reiners JJ Jr. Quantitative RT-PCR on CYP1A1 heterogeneous nuclear RNA: a surrogate for the in vitro transcript run-on assay. Biotechniques 20: 47-477, 1996.
7. Fennelly J, Frank O, Baker H, Leevy CM. Peripheral neuropathy of the alcoholic. I. Aetiological role of aneurin and other B-complex vitamins. Br Med J 2: 1290-1292, 1965.
8. Fujimura M, Yamamoto S, Murata T, Yasujima T, Inoue K, Ohta KY, Yuasa H. Functional characteristics of the human ortholog of riboflavin transporter 2 and riboflavin-responsive expression of its rat ortholog in the small intestine indicate its involvement in riboflavin absorption. J Nutr 140: 1722-1727, 2010.
9. Hell D, Six P. Thiamin, riboflavin-und pyridoxine-versorgung bie chronicschem alkoholismus. Dtsch Med Wochenschr 102: 962-966, 1977.
10. Hopfer U, Nelson K, Perrotto J, Isselbacher KJ. Glucose transport in isolated brush border membrane from rat small intestine. J Biol Chem 248: 25-32, 1973.
11. Iinuma S. Synthesis of riboflavin by intestinal bacteria. J Vitaminol (Kyoto) 1: 6-13, 1955.
12. Kasper H. Vitamin absorption in the colon. Am J Proctol 21: 341-345, 1970.
13. Kohler CU, Roos PH. Focus on the intermediate state: immature mRNA of cytochrome P450-methods and insights. Anal Bioanal Chem 392: 1109-1122, 2008.
14. Kubisch CH, Gukovsky I, Lugea A, Pandol SJ, Kuick R, Misek DE, Hanash SM, Logsdon CD. Long-term ethanol consumption alters pancreatic gene expression in rats: a possible connection to pancreatic injury. Pancreas 33: 68-76, 2006.
15. Kumar CK, Yanagawa N, Ortiz A, Said HM. Mechanism and regulation of riboflavin uptake by human renal proximal tubule epithelial cell line HK-2. Am J Physiol Renal Physiol 274: F104-F110, 1998.
16. Law LK, Tang NL, Hui J, Fung SL, Ruiter J, Wanders RJ, Fok TF, Lam CW. Novel mutations in ETFDH gene in Chinese patients with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency. Clin Chim Acta 404: 95-99, 2009.
17. Leevy CM, Baker H. Vitamins and alcoholism. Am J Clin Nutr 21: 1325-1328, 1968.
18. Li HS, Zhang JY, Thompson BS, Deng XY, Ford ME, Wood PG, Stolz DB, Eagon PK, Whitcomb DC. Rat mitochondrial ATP synthase ATP5G3:cloning and upregulation in pancreas after chronic ethanol feeding. Physiol Genomics 6: 91-98, 2001.
19. Liang WC, Ohkuma A, Hayashi YK, Lopez LC, Hirano M, Nonaka I, Noguchi S, Chen LH, Jong YJ, Nishino I. ETFDH mutations, CoQ10 levels, and respiratory chain activities in patients with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency. Neuromuscul Disord 19: 212-216, 2009.
20. Lieber CS, DeCarli LM. Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol 24: 197-211, 1989.
21. Livek KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta DeltaC(T) method. Methods 25: 402-408, 2001.
22. Majumdar SK, Shaw GK, Thomson AD. Vitamin utilization status in chronic alcoholics. Internat J Vit Nutr Res 51: 54-58, 1981.
23. Middleton HM. Uptake of riboflavin by rat intestinal mucosa in vitro. J Nutr 120: 588-593, 1985.
24. Neville JN, Eagles JA, Samson G, Olson RE. Nutritional status of alcoholics. Am J Clin Nutr 21: 1329-1340, 1968.
25. Pangrekar J, Krishnaswamy K, Jagadeesan V. Effects of riboflavin deficiency and riboflavin administration on carcinogen-DNA binding. Food Chem Toxicol 31: 745-750, 1993.
26. Rajendram R, Preedy VR. Effect of alcohol consumption on the gut. Dig Dis 23: 214-221, 2005.
27. Rosenthal WS, Adham NF, Lopez R, Cooperman JM. Riboflavin deficiency in complicated chronic alcoholism. Am J Clin Nutr 26: 858-860, 1973.
28. Said HM, Arianas P. Transport of riboflavin in human intestinal brush border membrane vesicles. Gastroenterology 100: 82-88, 1990.
29. Said HM, Hollander D, Mohammadkhani R. Uptake of riboflavin by intestinal basolateral membrane vesicles: a specialized carrier-mediated process. Biochim Biophys Acta 1148: 263-268, 1993.
30. Said HM, Ma TY. Mechanism of riboflavine uptake by Caco-2 human intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 266: G15-G21, 1994.
31. Said HM, Ross C. Riboflavin. In: Modern Nutrition in Health and Disease Modern Nutrition in Health and Disease (11th ed.), edited by Ross C, Caballero B, Cousins RJ, Tucker KL, Ziegler TR. 2011, p. 325-330.
32. Salaspuro M. Bacterioclonic pathway for ethanol oxidation: characteristics and implications. Ann Med 28: 195-200, 1996.
33. Scalera V, Storelli C, Storelli-Joss C, Haase W, Murer H. A simple and fast method for the isolation of basolateral plasma membranes from rat small-intestinal epithelial cells. Biochem J 186: 177-181, 1980.
34. Sorrell MF, Frank O, Thompson AD, Aquino A, Baker H. Absorption of vitamins from the large intestine. Nutr Res Int 3: 143-148, 1971.
35. Subramanian VS, Rapp L, Marchant JS, Said HM. Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells,. Am J Physiol Gastrointest Liver Physiol 301: G100-G109, 2011.
36. Subramanian VS, Subramanya SB, Rapp L, Marchant JS, Ma TY, Said HM. Differential expression of human riboflavin transporters-1,-2, and-3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake. Biochim Biophys Acta 1808: 3016-3021, 2011.
37. Subramanian VS, Ghosal A, Subramanya SB, Lytle C, Said HM. Differentiation-dependent regulation of intestinal vitamin B2 uptake: Studies utilizing human derived intestinal epithelial Caco-2 cells and native rat intestine. Am J Physiol Gastrointest Liver Physiol 304: G741-G748, 2013.
38. Subramanya SB, Subramanian VS, Sekar VT, Said HM. Thiamin uptake by pancreatic cells: effect of chronic alcohol feeding/exposure. Am J Physiol Gastrointest Liver Physiol 301: G896-G904, 2011.
39. Tomie S, Yuasa H, Inoue K, Watanabe J. Transport functions of riboflavin carriers in the rat small intestine and colon: site difference and effects of tricyclic-type drugs. Drug Deliv 8: 119-124, 2001.
40. Tu BP, Ho-Schleyer SC, Travers KJ, Weissman JS. Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science 290: 1571-1574, 2000.
41. Yamamoto S, Inoue K, Ohta KY, Fukatsu R, Maeda JY, Yoshida Y, Yuasa H. Identification and functional characterization of rat riboflavin transporter 2. J Biochem 145: 437-443, 2009.
42. Yanagawa N, Jo OD, Said HM. Riboflavin transport by rabbit renal brush border membrane vesicles. Biochim Biophys Acta 1330: 172-178, 1997.
43. Yanagawa N, Jo OD, Said HM. Riboflavin transport by rabbit renal basolateral membrane vesicles. Biochim Biophys Acta 1415: 56-62, 1998.
44. Yao Y, Yonezawa A, Yoshimatsu H, Masuda S, Katsura T, Inui K. Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain. J Nutr 140: 1220-1226, 2010.
45. Yonezawa A, Masuda S, Katsura T, Inui K. Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1. Am J Physiol Cell Physiol 295: C632-C641, 2008.
46. Zinchuk V, Zinchuk O, Akimaru K, Moriya F, Okada T. Ethanol consumption alters expression and colocalization of bile salt export pump and multidrug resistance protein 2 in the rat. Histochem Cell Biol 127: 503-512, 2007.