메뉴 건너뛰기




Volumn 28, Issue 3, 1996, Pages 195-200

Bacteriocolonic pathway for ethanol oxidation: Characteristics and implications

Author keywords

Acetaldehyde; Alcohol; Alcohol dehydrogenase; Alcohol metabolism; Alcoholic fermentation; Alcoholic liver injury; Aldehyde dehydrogenase; Bacteria; Colon; Colon cancer; Colon polyps; Diarrhoea; Ethanol; Ethanol calories; Ethanol metabolism; Rectum cancer

Indexed keywords

ACETALDEHYDE; ACETIC ACID; ALCOHOL DEHYDROGENASE; ANTIBIOTIC AGENT;

EID: 0029898316     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853899609033120     Document Type: Short Survey
Times cited : (123)

References (88)
  • 1
    • 0015876114 scopus 로고
    • Distribution of ethanol in the human gastrointestinal tract
    • Halstedt CH, Robles EA, Mezey E. Distribution of ethanol in the human gastrointestinal tract. Am J Clin Nutr 1973; 26: 831-4.
    • (1973) Am J Clin Nutr , vol.26 , pp. 831-834
    • Halstedt, C.H.1    Robles, E.A.2    Mezey, E.3
  • 2
    • 0020407499 scopus 로고
    • Hypothesis: Metabolic activity of the colonic bacteria influences organ injury from ethanol
    • Lewitt MD, Doizaki W, Levine AS. Hypothesis: metabolic activity of the colonic bacteria influences organ injury from ethanol. Hepatology 1982; 2: 598-600.
    • (1982) Hepatology , vol.2 , pp. 598-600
    • Lewitt, M.D.1    Doizaki, W.2    Levine, A.S.3
  • 3
    • 0020513935 scopus 로고
    • Immunohistochemical localization of alcohol dehydrogenase in the human tract
    • Pestalozzi DM, Bühler R, von Wartburg J-P, Hess M. Immunohistochemical localization of alcohol dehydrogenase in the human tract. Gastroenterology 1983; 85: 1011-6.
    • (1983) Gastroenterology , vol.85 , pp. 1011-1016
    • Pestalozzi, D.M.1    Bühler, R.2    Von Wartburg, J.-P.3    Hess, M.4
  • 4
    • 0028307632 scopus 로고
    • Cellular localization of the class I alcohol dehydrogenase transcript in adult rat tissues
    • Tietjen TG, Mjaatvedt CH, Yang VW. Cellular localization of the class I alcohol dehydrogenase transcript in adult rat tissues. Histochem J 1994; 26: 526-32.
    • (1994) Histochem J , vol.26 , pp. 526-532
    • Tietjen, T.G.1    Mjaatvedt, C.H.2    Yang, V.W.3
  • 5
    • 0027996232 scopus 로고
    • Genetic polymorphism and activities of human colon alcohol and aldehyde dehydrogenases: No gender and age differences
    • Yin S-J, Liao C-H, Wu C-W, Jao S-W. Genetic polymorphism and activities of human colon alcohol and aldehyde dehydrogenases: no gender and age differences. Alcohol Clin Exp Res 1994; 18: 1256-60.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 1256-1260
    • Yin, S.-J.1    Liao, C.-H.2    Wu, C.-W.3    Jao, S.-W.4
  • 6
    • 85035162417 scopus 로고    scopus 로고
    • Aldehyde dehydrogenases of the rat colon: Comparison with other tissues of the alimentary tract and the liver
    • in press
    • Koivisto T, Salaspuro M. Aldehyde dehydrogenases of the rat colon: comparison with other tissues of the alimentary tract and the liver. Alcohol Clin Exp Res (in press).
    • Alcohol Clin Exp Res
    • Koivisto, T.1    Salaspuro, M.2
  • 7
    • 0021263003 scopus 로고
    • Enhancement of 1,2-dimethylhydrazine-induced rectal carcinogenesis following chronic ethanol consumption in the rat
    • Seitz HK, Czykan P, Wahldherr R, et al. Enhancement of 1,2-dimethylhydrazine-induced rectal carcinogenesis following chronic ethanol consumption in the rat. Gastroenterology 1984; 86: 886-91.
    • (1984) Gastroenterology , vol.86 , pp. 886-891
    • Seitz, H.K.1    Czykan, P.2    Wahldherr, R.3
  • 8
    • 0025136961 scopus 로고
    • Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat
    • Seitz HK, Simanowski UA, Garzon FT, et al. Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat. Gastroenterology 1990; 98: 406-13.
    • (1990) Gastroenterology , vol.98 , pp. 406-413
    • Seitz, H.K.1    Simanowski, U.A.2    Garzon, F.T.3
  • 9
    • 0028212644 scopus 로고
    • Molecular characterization of microbial alcohol dehydrogenase
    • Reid MF, Fewson CA. Molecular characterization of microbial alcohol dehydrogenase. Crit Rev Microbiol 1994; 20: 13-56.
    • (1994) Crit Rev Microbiol , vol.20 , pp. 13-56
    • Reid, M.F.1    Fewson, C.A.2
  • 10
    • 0019269276 scopus 로고
    • Chemical and fuel production by anaerobic bacteria
    • Zeikus JG. Chemical and fuel production by anaerobic bacteria. Annu Rev Microbiol 1980; 34: 423-64.
    • (1980) Annu Rev Microbiol , vol.34 , pp. 423-464
    • Zeikus, J.G.1
  • 11
    • 0023039990 scopus 로고
    • The two alcohol dehydrogenases of Zymomonas mobilis. Purification by differential dye ligand chromatography, molecular characterisation and physiological roles
    • Neale AD, Scopes RK, Kelly JM, Wettenhall REH. The two alcohol dehydrogenases of Zymomonas mobilis. Purification by differential dye ligand chromatography, molecular characterisation and physiological roles. Eur J Biochem 1986; 154: 119-24.
    • (1986) Eur J Biochem , vol.154 , pp. 119-124
    • Neale, A.D.1    Scopes, R.K.2    Kelly, J.M.3    Wettenhall, R.E.H.4
  • 12
    • 0014813667 scopus 로고
    • The physiological role of liver alcohol dehydrogenase
    • Krebs HA, Perkins JR. The physiological role of liver alcohol dehydrogenase. Biochem J 1970; 118: 635-44.
    • (1970) Biochem J , vol.118 , pp. 635-644
    • Krebs, H.A.1    Perkins, J.R.2
  • 13
    • 0022657702 scopus 로고
    • Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats
    • Baraona E, Julkunen R, Tannenbaum L, Lieber CS. Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats. Gastroenterology 1986; 90: 103-10.
    • (1986) Gastroenterology , vol.90 , pp. 103-110
    • Baraona, E.1    Julkunen, R.2    Tannenbaum, L.3    Lieber, C.S.4
  • 15
    • 0016793479 scopus 로고
    • Endogenous ethanol production and hepatic disease following jejunoileal bypass for morbid obesity
    • Mezey E, Imbembo AL, Potter JJ, Rent KC, Lombardo L, Holt PR. Endogenous ethanol production and hepatic disease following jejunoileal bypass for morbid obesity. Am J Clin Nutr 1975; 28: 1277-83.
    • (1975) Am J Clin Nutr , vol.28 , pp. 1277-1283
    • Mezey, E.1    Imbembo, A.L.2    Potter, J.J.3    Rent, K.C.4    Lombardo, L.5    Holt, P.R.6
  • 16
    • 0021637537 scopus 로고
    • Intragastrointestinal alcohol fermentation syndrome: Report of two cases and review of the literature
    • Kaji H, Asanuma Y, Yahara O, et al. Intragastrointestinal alcohol fermentation syndrome: report of two cases and review of the literature. J Forensic Sci Soc 1984; 24: 461-71.
    • (1984) J Forensic Sci Soc , vol.24 , pp. 461-471
    • Kaji, H.1    Asanuma, Y.2    Yahara, O.3
  • 18
    • 0019454934 scopus 로고
    • Contribution of oropharynx microflora and of lung microsomes to acetaldehyde in expired air after alcohol ingestion
    • Pikkarainen PH, Baraona E, Jauhonen P, Seitz HK, Lieber CS. Contribution of oropharynx microflora and of lung microsomes to acetaldehyde in expired air after alcohol ingestion. J Lab Clin Med 1981; 97: 631-6.
    • (1981) J Lab Clin Med , vol.97 , pp. 631-636
    • Pikkarainen, P.H.1    Baraona, E.2    Jauhonen, P.3    Seitz, H.K.4    Lieber, C.S.5
  • 21
    • 0028846715 scopus 로고
    • Alcohol metabolism in Helicobacter pylori-infected stomach
    • Roine RP, Salmela KS, Salaspuro M. Alcohol metabolism in Helicobacter pylori-infected stomach. Ann Med 1995; 27: 583-8.
    • (1995) Ann Med , vol.27 , pp. 583-588
    • Roine, R.P.1    Salmela, K.S.2    Salaspuro, M.3
  • 23
    • 0025318381 scopus 로고
    • Intestinal microflora: Metabolism of drugs and carcinogens
    • Goldin BR. Intestinal microflora: metabolism of drugs and carcinogens. Ann Med 1990; 22: 43-8.
    • (1990) Ann Med , vol.22 , pp. 43-48
    • Goldin, B.R.1
  • 24
    • 0017689540 scopus 로고
    • Bicentennial overview of intestinal microecology
    • Luckey TD. Bicentennial overview of intestinal microecology. Am J Clin Nutr 1977; 30: 1753-61.
    • (1977) Am J Clin Nutr , vol.30 , pp. 1753-1761
    • Luckey, T.D.1
  • 25
    • 0020539371 scopus 로고
    • Fermentation in the human large intestine: Evidence and implications for health
    • Cummings JH. Fermentation in the human large intestine: evidence and implications for health. Lancet 1983; i: 1206-9.
    • (1983) Lancet , vol.1 , pp. 1206-1209
    • Cummings, J.H.1
  • 26
    • 0023733683 scopus 로고
    • Meat, starch, and nonstarch polysaccharides and large bowel cancer
    • Bingham SA. Meat, starch, and nonstarch polysaccharides and large bowel cancer. Am J Clin Nutr 1988; 48: 762-7.
    • (1988) Am J Clin Nutr , vol.48 , pp. 762-767
    • Bingham, S.A.1
  • 28
    • 85035166857 scopus 로고    scopus 로고
    • In vitro alcohol dehydrogenase mediated acetaldehyde production by aerobic bacteria representing the normal colonic flora in man
    • in press
    • Jokelainen K, Siitonen A, Jousimies-Somer H, Nosova T, Heine R, Salaspuro M. In vitro alcohol dehydrogenase mediated acetaldehyde production by aerobic bacteria representing the normal colonic flora in man. Alcohol Clin Exp Res (in press).
    • Alcohol Clin Exp Res
    • Jokelainen, K.1    Siitonen, A.2    Jousimies-Somer, H.3    Nosova, T.4    Heine, R.5    Salaspuro, M.6
  • 29
    • 85035159902 scopus 로고    scopus 로고
    • High intracolonic acetaldehyde levels produced by a bacteriocolonic pathway for ethanol oxidation in piglets
    • in press
    • Jokelainen K, Matysiak-Budnik T, Mäkisalo H, Höckerstedt K, Salaspuro M. High intracolonic acetaldehyde levels produced by a bacteriocolonic pathway for ethanol oxidation in piglets. Gut (in press).
    • Gut
    • Jokelainen, K.1    Matysiak-Budnik, T.2    Mäkisalo, H.3    Höckerstedt, K.4    Salaspuro, M.5
  • 32
    • 0025718848 scopus 로고
    • Perspectives: Do alcohol calories count
    • Lieber CS. Perspectives: do alcohol calories count. Am J Clin Nutr 1991; 54: 976-82.
    • (1991) Am J Clin Nutr , vol.54 , pp. 976-982
    • Lieber, C.S.1
  • 34
    • 0019408517 scopus 로고
    • Alcohol inhibition of rectosigmoid motility in humans
    • Berenson MM, Avner DL. Alcohol inhibition of rectosigmoid motility in humans. Digestion 1981; 22: 210-5.
    • (1981) Digestion , vol.22 , pp. 210-215
    • Berenson, M.M.1    Avner, D.L.2
  • 36
    • 0018129754 scopus 로고
    • Alcohol ingestion-induced changes in the human rectal mucosa: Light and electron microscopic studies
    • Brozinsky S, Fani K, Grosberg SJ, Wapnick S. Alcohol ingestion-induced changes in the human rectal mucosa: light and electron microscopic studies. Dis Col Rect 1978; 21: 329-35.
    • (1978) Dis Col Rect , vol.21 , pp. 329-335
    • Brozinsky, S.1    Fani, K.2    Grosberg, S.J.3    Wapnick, S.4
  • 38
    • 0027968127 scopus 로고
    • Enhancement of ethanol induced rectal mucosal hyper regeneration with age in F344 rats
    • Simanowski UA, Suter P, Russell RM, et al. Enhancement of ethanol induced rectal mucosal hyper regeneration with age in F344 rats. Gut 1994; 35: 1102-6.
    • (1994) Gut , vol.35 , pp. 1102-1106
    • Simanowski, U.A.1    Suter, P.2    Russell, R.M.3
  • 39
    • 0028958498 scopus 로고
    • Effect of alcohol on gastrointestinal cell regeneration as a possible mechanism in alcohol-associated carcinogenesis
    • Simanowski UA, Stickel F, Maier H, Gärtner U, Seitz HK. Effect of alcohol on gastrointestinal cell regeneration as a possible mechanism in alcohol-associated carcinogenesis. Alcohol 1995; 12: 111-5.
    • (1995) Alcohol , vol.12 , pp. 111-115
    • Simanowski, U.A.1    Stickel, F.2    Maier, H.3    Gärtner, U.4    Seitz, H.K.5
  • 40
    • 0028816604 scopus 로고
    • Diet, alcohol, and smoking and the occurrence of hyperplastic polyps of the colon and rectum
    • Kearney J, Giovannucci E, Rimm EB, et al. Diet, alcohol, and smoking and the occurrence of hyperplastic polyps of the colon and rectum. Cancer Causes Control 1995; 6: 45-56.
    • (1995) Cancer Causes Control , vol.6 , pp. 45-56
    • Kearney, J.1    Giovannucci, E.2    Rimm, E.B.3
  • 41
    • 0028897343 scopus 로고
    • Cigarette smoking and alcohol consumption as risk factors for colorectal adenomatous polyps
    • Martinez ME, McPherson RS, Annegers JF, Levin B. Cigarette smoking and alcohol consumption as risk factors for colorectal adenomatous polyps. J Natl Cancer Inst 1995; 87: 274-9.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 274-279
    • Martinez, M.E.1    McPherson, R.S.2    Annegers, J.F.3    Levin, B.4
  • 43
    • 0028951793 scopus 로고
    • Alcohol consumption and risk of cancer in humans: An overview
    • Longnecker MP. Alcohol consumption and risk of cancer in humans: an overview. Alcohol 1995; 12: 87-96.
    • (1995) Alcohol , vol.12 , pp. 87-96
    • Longnecker, M.P.1
  • 44
    • 0002462657 scopus 로고
    • Metabolism and toxicity of acetaldehyde
    • Seitz HK, Kommerell B, eds. Berlin: Springer Verlag
    • Salaspuro M, Lindros K. Metabolism and toxicity of acetaldehyde. In: Seitz HK, Kommerell B, eds. Alcohol Related Diseases in Gastroenterology. Berlin: Springer Verlag, 1985: 106-23.
    • (1985) Alcohol Related Diseases in Gastroenterology , pp. 106-123
    • Salaspuro, M.1    Lindros, K.2
  • 46
    • 0027301303 scopus 로고
    • Aetiology and pathogenesis of alcoholic liver disease
    • Lieber CS. Aetiology and pathogenesis of alcoholic liver disease. Baillieres Clin Gastroenterol 1993; 7: 581-608.
    • (1993) Baillieres Clin Gastroenterol , vol.7 , pp. 581-608
    • Lieber, C.S.1
  • 47
    • 0027631208 scopus 로고
    • Acetaldehyde/ protein interactions: Are they involved in the pathogenesis of alcoholic liver disease?
    • Worrall S, deJersey J, Nicholls R, Wilce P. Acetaldehyde/ protein interactions: are they involved in the pathogenesis of alcoholic liver disease? Dig Dis 1993; 11: 265-77.
    • (1993) Dig Dis , vol.11 , pp. 265-277
    • Worrall, S.1    DeJersey, J.2    Nicholls, R.3    Wilce, P.4
  • 48
    • 0027352765 scopus 로고
    • Acetaldehyde adducts of proteins: Diagnostic and pathogenetic implications in diseases caused by excessive alcohol consumption
    • Niemelä O. Acetaldehyde adducts of proteins: diagnostic and pathogenetic implications in diseases caused by excessive alcohol consumption. Scand J Clin Chem 1993; 213: 45-54.
    • (1993) Scand J Clin Chem , vol.213 , pp. 45-54
    • Niemelä, O.1
  • 49
    • 0028190183 scopus 로고
    • Alcoholic liver disease: New concepts of pathogenesis and treatment
    • Bloor JH, Mapoles JE, Simon FR. Alcoholic liver disease: new concepts of pathogenesis and treatment. Adv Int Med 1994; 39: 49-92.
    • (1994) Adv Int Med , vol.39 , pp. 49-92
    • Bloor, J.H.1    Mapoles, J.E.2    Simon, F.R.3
  • 50
    • 0028352955 scopus 로고
    • Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation
    • Niemelä O, Parkkila S, Ylä-Herttuala S, et al. Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation. Lab Invest 1994; 70: 537-46.
    • (1994) Lab Invest , vol.70 , pp. 537-546
    • Niemelä, O.1    Parkkila, S.2    Ylä-Herttuala, S.3
  • 51
    • 0022376542 scopus 로고
    • Hypothesis: Alcoholic liver injury and covalent binding of acetaldehyde
    • Sorrell MF, Tuma DJ. Hypothesis: alcoholic liver injury and covalent binding of acetaldehyde. Alcohol Clin Exp Res 1985; 9: 306-9.
    • (1985) Alcohol Clin Exp Res , vol.9 , pp. 306-309
    • Sorrell, M.F.1    Tuma, D.J.2
  • 52
    • 0023578940 scopus 로고
    • The detection of acetaldehyde/liver plasma membrane protein adducts formed in vivo by alcohol, feeding
    • Barry RE, Williams AJK, McGivan JD. The detection of acetaldehyde/liver plasma membrane protein adducts formed in vivo by alcohol, feeding. Liver 1987; 7: 364-8.
    • (1987) Liver , vol.7 , pp. 364-368
    • Barry, R.E.1    Williams, A.J.K.2    McGivan, J.D.3
  • 53
    • 0023860256 scopus 로고
    • Detection of protein-acetaldehyde adduct in the liver of rats fed alcohol chronically
    • Lin RC, Smith SR, Lumeng L. Detection of protein-acetaldehyde adduct in the liver of rats fed alcohol chronically. J Clin Invest 1988; 81: 615-9.
    • (1988) J Clin Invest , vol.81 , pp. 615-619
    • Lin, R.C.1    Smith, S.R.2    Lumeng, L.3
  • 54
    • 0028125857 scopus 로고
    • Acetaldehyde-modified epitopes in liver biopsy specimens of alcoholic and nonalcoholic patients: Localization and association with progression to liver fibrosis
    • Holstege A, Bedosa P, Poynard T, et al. Acetaldehyde-modified epitopes in liver biopsy specimens of alcoholic and nonalcoholic patients: localization and association with progression to liver fibrosis. Hepatology 1994; 19: 367-74.
    • (1994) Hepatology , vol.19 , pp. 367-374
    • Holstege, A.1    Bedosa, P.2    Poynard, T.3
  • 55
    • 0024230514 scopus 로고
    • Mechanisms of acetaldehyde hepatotoxicity
    • Lauterburg BH, Bilzer M. Mechanisms of acetaldehyde hepatotoxicity. J Hepatol 1988; 7: 384-90.
    • (1988) J Hepatol , vol.7 , pp. 384-390
    • Lauterburg, B.H.1    Bilzer, M.2
  • 56
    • 0002099005 scopus 로고
    • Epidemiological aspects of alcohol and alcoholic liver disease, ethanol metabolism, and pathogenesis of alcoholic liver injury
    • McIntyre N, Benhamou J-P, Bircher J, Rizzetto M, Rodes J, eds. Oxford: University Press
    • Salaspuro M. Epidemiological aspects of alcohol and alcoholic liver disease, ethanol metabolism, and pathogenesis of alcoholic liver injury. In: McIntyre N, Benhamou J-P, Bircher J, Rizzetto M, Rodes J, eds. Oxford Textbook of Clinical Hepatology. Oxford: University Press, 1991: 791-810.
    • (1991) Oxford Textbook of Clinical Hepatology , pp. 791-810
    • Salaspuro, M.1
  • 57
    • 0028131989 scopus 로고
    • Hepatic and metabolic effects of ethanol: Pathogenesis and prevention
    • Lieber CS. Hepatic and metabolic effects of ethanol: pathogenesis and prevention. Ann Med 1994; 26: 325-30.
    • (1994) Ann Med , vol.26 , pp. 325-330
    • Lieber, C.S.1
  • 58
    • 0028029554 scopus 로고
    • Mechanisms of ethanol-drug-nutrition interactions
    • Lieber CS. Mechanisms of ethanol-drug-nutrition interactions. J Toxicol Clin Toxicol 1994; 32: 631-81.
    • (1994) J Toxicol Clin Toxicol , vol.32 , pp. 631-681
    • Lieber, C.S.1
  • 59
    • 0019973469 scopus 로고
    • Toxicity of acetaldehyde in rats. Acute and subacute studies
    • Appelman LM, Woutersen RA, Feron VJ. Toxicity of acetaldehyde in rats. Acute and subacute studies. Toxicology 1982; 23: 293-307.
    • (1982) Toxicology , vol.23 , pp. 293-307
    • Appelman, L.M.1    Woutersen, R.A.2    Feron, V.J.3
  • 60
    • 84952114564 scopus 로고
    • Repeated exposure to acetaldehyde vapor. Studies in Syrian golden hamsters
    • Kruysse A, Feron VJ, Til HP. Repeated exposure to acetaldehyde vapor. Studies in Syrian golden hamsters. Arch Environ Health 1975; 30: 449-52.
    • (1975) Arch Environ Health , vol.30 , pp. 449-452
    • Kruysse, A.1    Feron, V.J.2    Til, H.P.3
  • 61
    • 0021904450 scopus 로고
    • Glass fibers and vapor phase components of cigarette smoke as cofactors in experimental respiratory tract carcinogenesis
    • Feron VJ, Kuper CF, Spit BJ, Reuzel PG, Woutersen RA. Glass fibers and vapor phase components of cigarette smoke as cofactors in experimental respiratory tract carcinogenesis. Carcinog Compr Surv 1985; 8: 93-118.
    • (1985) Carcinog Compr Surv , vol.8 , pp. 93-118
    • Feron, V.J.1    Kuper, C.F.2    Spit, B.J.3    Reuzel, P.G.4    Woutersen, R.A.5
  • 62
    • 0022014717 scopus 로고
    • Acetaldehyde
    • International Agency For Research on Cancer. Working Group on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Acetaldehyde. IARC Monogr Eval Carcinog Risks Hum 1985; 36: 101-32.
    • (1985) IARC Monogr Eval Carcinog Risks Hum , vol.36 , pp. 101-132
  • 65
    • 0028902333 scopus 로고
    • Mechanism of acetaldehyde-mediated growth inhibition: Delayed cell cycle progression and induction of apoptosis
    • Zimmerman BT, Crawford GD, Dahl R, Simon FR, Mapoles J. Mechanism of acetaldehyde-mediated growth inhibition: delayed cell cycle progression and induction of apoptosis. Alcohol Clin Exp Res 1995; 19: 434-40.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 434-440
    • Zimmerman, B.T.1    Crawford, G.D.2    Dahl, R.3    Simon, F.R.4    Mapoles, J.5
  • 66
    • 0023543188 scopus 로고
    • Antibodies against acetaldehyde modified protein epitopes in human alcoholics
    • Niemelä O, Klajner F, Orrego H. Antibodies against acetaldehyde modified protein epitopes in human alcoholics. Hepatology 1987; 7: 1210-4.
    • (1987) Hepatology , vol.7 , pp. 1210-1214
    • Niemelä, O.1    Klajner, F.2    Orrego, H.3
  • 68
    • 0001202827 scopus 로고
    • Sulfonamide drugs as protective agents against carbon tetrachloride poisoning
    • Leach BE, Forbes JC. Sulfonamide drugs as protective agents against carbon tetrachloride poisoning. Proc Soc Exp Biol Med 1941; 48: 361-3.
    • (1941) Proc Soc Exp Biol Med , vol.48 , pp. 361-363
    • Leach, B.E.1    Forbes, J.C.2
  • 70
    • 0010537933 scopus 로고
    • Antibiotics and liver injury
    • Gyorgy P. Antibiotics and liver injury. Ann NY Acad Sci 1954; 57: 925-32.
    • (1954) Ann NY Acad Sci , vol.57 , pp. 925-932
    • Gyorgy, P.1
  • 71
    • 0016761608 scopus 로고
    • The role of endotoxin in liver injury
    • Nolan JP. The role of endotoxin in liver injury. Gastroenterology 1975; 68: 1346-56.
    • (1975) Gastroenterology , vol.68 , pp. 1346-1356
    • Nolan, J.P.1
  • 72
    • 0024436292 scopus 로고
    • Intestinal endotoxins as mediators of hepatic injury
    • Nolan JP. Intestinal endotoxins as mediators of hepatic injury. Hepatology 1989; 10: 887-91.
    • (1989) Hepatology , vol.10 , pp. 887-891
    • Nolan, J.P.1
  • 73
    • 0017047716 scopus 로고
    • Portal venous and systemic endotoxaemia in patients without liver disease and systemic endotoxaemia in patients with cirrhosis
    • Prytz H, Holst-Christensen J, Korner B, Liehr H. Portal venous and systemic endotoxaemia in patients without liver disease and systemic endotoxaemia in patients with cirrhosis. Scand J Gastroenterol 1976; 11: 857-63.
    • (1976) Scand J Gastroenterol , vol.11 , pp. 857-863
    • Prytz, H.1    Holst-Christensen, J.2    Korner, B.3    Liehr, H.4
  • 75
    • 0023145010 scopus 로고
    • Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess
    • Bode C, Kugler V, Bode JC. Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess. J Hepatol 1987; 4: 8-14.
    • (1987) J Hepatol , vol.4 , pp. 8-14
    • Bode, C.1    Kugler, V.2    Bode, J.C.3
  • 76
    • 0023901892 scopus 로고
    • Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral venous blood in patients with cirrhosis
    • Lumsden AB, Henderson JM, Kutner MH. Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral venous blood in patients with cirrhosis. Hepatology 1988; 8: 232-6.
    • (1988) Hepatology , vol.8 , pp. 232-236
    • Lumsden, A.B.1    Henderson, J.M.2    Kutner, M.H.3
  • 77
    • 0026078067 scopus 로고
    • Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: Reevaluation with an improved chromogenic assay
    • Fukui H, Brauner B, Bode J Ch, Bode Ch. Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay. J Hepatol 1991; 12: 162-9.
    • (1991) J Hepatol , vol.12 , pp. 162-169
    • Fukui, H.1    Brauner, B.2    Bode, J.Ch.3    Bode, Ch.4
  • 78
    • 0026079145 scopus 로고
    • Endotoxemia in liver disease - Time for re-appraisal?
    • Triger DR. Endotoxemia in liver disease - time for re-appraisal? J Hepatol 1991; 12: 136-8.
    • (1991) J Hepatol , vol.12 , pp. 136-138
    • Triger, D.R.1
  • 79
    • 0029384834 scopus 로고
    • Alcohol and endotoxin: Another path to alcoholic liver injury?
    • Schenker S, Bay MK. Alcohol and endotoxin: another path to alcoholic liver injury? Alcohol Clin Exp Res 1995; 19: 1364-6.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 1364-1366
    • Schenker, S.1    Bay, M.K.2
  • 80
    • 0021352090 scopus 로고
    • The leaky gut of alcoholism: Possible route of entry for toxic compounds
    • Bjarnason I, Ward K, Peters TJ. The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet 1984; i: 179-82.
    • (1984) Lancet , vol.1 , pp. 179-182
    • Bjarnason, I.1    Ward, K.2    Peters, T.J.3
  • 82
    • 0023222579 scopus 로고
    • Endotoxin induced hepatic necrosis in rats on alcohol diet
    • Bhagwandeen BS, Apte M, Manwarring L, Dickeson J. Endotoxin induced hepatic necrosis in rats on alcohol diet. J Pathol 1987; 151: 47-53.
    • (1987) J Pathol , vol.151 , pp. 47-53
    • Bhagwandeen, B.S.1    Apte, M.2    Manwarring, L.3    Dickeson, J.4
  • 83
    • 0026051653 scopus 로고
    • Endotoxin hepatotoxicity augmented by ethanol
    • Shibayama Y, Asaka S, Nakata K. Endotoxin hepatotoxicity augmented by ethanol. Exp Mol Pathol 1991; 55: 196-202.
    • (1991) Exp Mol Pathol , vol.55 , pp. 196-202
    • Shibayama, Y.1    Asaka, S.2    Nakata, K.3
  • 84
    • 0024315710 scopus 로고
    • Endotoxin-induced hypercoagulability: A possible aggravating factor of alcoholic liver disease
    • Arai M, Nakano S, Okuno F, et al. Endotoxin-induced hypercoagulability: a possible aggravating factor of alcoholic liver disease. Hepatology 1989; 9: 846-51.
    • (1989) Hepatology , vol.9 , pp. 846-851
    • Arai, M.1    Nakano, S.2    Okuno, F.3
  • 86
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • Adachi Y, Moore LE, Bradford BU, Gao W, Thurman RG. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995; 108: 218-24.
    • (1995) Gastroenterology , vol.108 , pp. 218-224
    • Adachi, Y.1    Moore, L.E.2    Bradford, B.U.3    Gao, W.4    Thurman, R.G.5
  • 87
    • 0028108372 scopus 로고
    • Inactivation of Kupffer cells prevents early alcohol-induced liver injury
    • Adachi Y, Bradford BU, Gao W, Bojes HK, Thurman RG. Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 1994; 20: 453-60.
    • (1994) Hepatology , vol.20 , pp. 453-460
    • Adachi, Y.1    Bradford, B.U.2    Gao, W.3    Bojes, H.K.4    Thurman, R.G.5
  • 88
    • 0028220726 scopus 로고
    • Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver disease
    • Nanji AA, Khettry U, Sadrzadeh SMH. Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver disease. Proc Soc Exp Biol Med 1994; 205: 243-7.
    • (1994) Proc Soc Exp Biol Med , vol.205 , pp. 243-247
    • Nanji, A.A.1    Khettry, U.2    Sadrzadeh, S.M.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.