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Volumn 33, Issue 1, 2006, Pages 68-76

Long-term ethanol consumption alters pancreatic gene expression in rats: A possible connection to pancreatic injury

Author keywords

Ethanol consumption; Gene profiling; Pancreatic gene expression; Pancreatitis

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ALCOHOL; CARRIER PROTEIN; FOLATE CARRIER; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; MESOTRYPSINOGEN; METALLOTHIONEIN; PANCREATITIS ASSOCIATE PROTEIN; RNA; TRYPSINOGEN; UNCLASSIFIED DRUG;

EID: 33745684928     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mpa.0000226878.81377.94     Document Type: Article
Times cited : (38)

References (50)
  • 2
    • 0032840174 scopus 로고    scopus 로고
    • Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin octapeptide
    • Pandol SJ, Periskic S, Gukovsky I, et al. Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin octapeptide. Gastroenterology. 1999;117(3):706-716.
    • (1999) Gastroenterology , vol.117 , Issue.3 , pp. 706-716
    • Pandol, S.J.1    Periskic, S.2    Gukovsky, I.3
  • 3
    • 0036080447 scopus 로고    scopus 로고
    • Alcohols enhance caerulein-induced zymogen activation in pancreatic acinar cells
    • Lu Z, Karne S, Kolodecik T, et al. Alcohols enhance caerulein-induced zymogen activation in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2002;282(3):G501-G507.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.282 , Issue.3
    • Lu, Z.1    Karne, S.2    Kolodecik, T.3
  • 4
    • 0031042856 scopus 로고    scopus 로고
    • Ethanol consumption and susceptibility of the pancreas to cerulein-induced pancreatitis
    • Ponnappa BC, Marciniak R, Schneider T, et al. Ethanol consumption and susceptibility of the pancreas to cerulein-induced pancreatitis. Pancreas. 1997;14(2):150-157.
    • (1997) Pancreas , vol.14 , Issue.2 , pp. 150-157
    • Ponnappa, B.C.1    Marciniak, R.2    Schneider, T.3
  • 5
    • 0023080603 scopus 로고
    • Exocytosis occurs at the lateral plasma membrane of the pancreatic acinar cell during supramaximal secretagogue stimulation
    • Scheele G, Adler G, Kern H. Exocytosis occurs at the lateral plasma membrane of the pancreatic acinar cell during supramaximal secretagogue stimulation. Gastroenterology. 1987;92(2):345-353.
    • (1987) Gastroenterology , vol.92 , Issue.2 , pp. 345-353
    • Scheele, G.1    Adler, G.2    Kern, H.3
  • 6
    • 0001030641 scopus 로고
    • Stimulus-secretion coupling in pancreatic acinar cells
    • Go VLW, Dimagno EP, Gardner JD, et al, eds. New York: Raven Press
    • Williams JA, Yule DI. Stimulus-secretion coupling in pancreatic acinar cells. In: Go VLW, Dimagno EP, Gardner JD, et al, eds. The Pancreas: Biology, Pathobiology, and Disease, 2nd ed. New York: Raven Press; 1993:167-170.
    • (1993) The Pancreas: Biology, Pathobiology, and Disease, 2nd Ed. , pp. 167-170
    • Williams, J.A.1    Yule, D.I.2
  • 7
    • 0031867966 scopus 로고    scopus 로고
    • Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats
    • Hofbauer B, Saluja AK, Lerch MM, et al. Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats. Am J Physiol. 1998;275:G352-G362.
    • (1998) Am J Physiol , vol.275
    • Hofbauer, B.1    Saluja, A.K.2    Lerch, M.M.3
  • 8
    • 0028963543 scopus 로고
    • Disassembly of rat pancreatic acinar cell cytoskeleton during supramaximal secretagogue stimulation
    • Jungermann J, Lerch MM, Weidenbach H, et al. Disassembly of rat pancreatic acinar cell cytoskeleton during supramaximal secretagogue stimulation. Am J Physiol. 1995;268:G328-G338.
    • (1995) Am J Physiol , vol.268
    • Jungermann, J.1    Lerch, M.M.2    Weidenbach, H.3
  • 9
    • 0025152120 scopus 로고
    • Effects of caerulein on the apical cytoskeleton of the pancreatic acinar cell
    • O'Konski MS, Pandol SJ. Effects of caerulein on the apical cytoskeleton of the pancreatic acinar cell. J Clin Invest. 1990;86(5):1649-1657.
    • (1990) J Clin Invest , vol.86 , Issue.5 , pp. 1649-1657
    • O'Konski, M.S.1    Pandol, S.J.2
  • 10
    • 1842775204 scopus 로고    scopus 로고
    • Role of cytokines and oxidative stress in the pathophysiology of acute pancreatitis: Therapeutical implications
    • Gomez-Cambronero LG, Sabater L, Pereda L, et al. Role of cytokines and oxidative stress in the pathophysiology of acute pancreatitis: therapeutical implications. Curr Drug Targets Inflamm Allergy. 2002;1:393-403.
    • (2002) Curr Drug Targets Inflamm Allergy , vol.1 , pp. 393-403
    • Gomez-Cambronero, L.G.1    Sabater, L.2    Pereda, L.3
  • 11
    • 0037145732 scopus 로고    scopus 로고
    • Time-course of oxygen free radical production in acinar cells during acute pancreatitis induced by pancreatic duct obstruction
    • Urunuela A, Sevillano S, de la Mano AM, et al. Time-course of oxygen free radical production in acinar cells during acute pancreatitis induced by pancreatic duct obstruction. Biochim Biophys Acta. 2002;1588(2):159-164.
    • (2002) Biochim Biophys Acta , vol.1588 , Issue.2 , pp. 159-164
    • Urunuela, A.1    Sevillano, S.2    De La Mano, A.M.3
  • 12
    • 1842611506 scopus 로고    scopus 로고
    • Ethanol modifies the actin cytoskeleton in rat pancreatic acinar cells - Comparison with effects of CCK
    • Siegmund E, Luthen F, Kunert J, et al. Ethanol modifies the actin cytoskeleton in rat pancreatic acinar cells - comparison with effects of CCK. Pancreatology. 2004;4(1):12-21.
    • (2004) Pancreatology , vol.4 , Issue.1 , pp. 12-21
    • Siegmund, E.1    Luthen, F.2    Kunert, J.3
  • 13
    • 0018832479 scopus 로고
    • Studies of pure pancreatic secretions in chronic alcoholic subjects without pancreatic insufficiency
    • Renner IG, Rinderknecht H, Valenzuela JE. Studies of pure pancreatic secretions in chronic alcoholic subjects without pancreatic insufficiency. Scand J Gastroenterol. 1980;15:241-244.
    • (1980) Scand J Gastroenterol , vol.15 , pp. 241-244
    • Renner, I.G.1    Rinderknecht, H.2    Valenzuela, J.E.3
  • 14
    • 33745689115 scopus 로고
    • Increased pancreatic acinar content and secretion of cationic trypsinogen following 30-day continuous ethanol intoxication in rats
    • Tsukamoto H, Sankaran H, Delgado G. Increased pancreatic acinar content and secretion of cationic trypsinogen following 30-day continuous ethanol intoxication in rats. Biochem Pharmacol. 1986;87:542-549.
    • (1986) Biochem Pharmacol , vol.87 , pp. 542-549
    • Tsukamoto, H.1    Sankaran, H.2    Delgado, G.3
  • 15
    • 33745689114 scopus 로고    scopus 로고
    • A murine model of ethanol-dependent pancreatic fibrosis
    • Perides G, Tao X, West N, et al. A murine model of ethanol-dependent pancreatic fibrosis. Gut. 2005;4:1-15.
    • (2005) Gut , vol.4 , pp. 1-15
    • Perides, G.1    Tao, X.2    West, N.3
  • 16
    • 11144237484 scopus 로고    scopus 로고
    • Chronic alcohol consumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats
    • Deng X, Wang L, Elm MS, et al. Chronic alcohol consumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats. Am J Pathol. 2005;166(1):93-106.
    • (2005) Am J Pathol , vol.166 , Issue.1 , pp. 93-106
    • Deng, X.1    Wang, L.2    Elm, M.S.3
  • 17
    • 0024409956 scopus 로고
    • Liquid diet technique of ethanol administration: 1989 Update
    • Lieber CS, DeCarli LM. Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol. 1989;24(3):197-211.
    • (1989) Alcohol Alcohol , vol.24 , Issue.3 , pp. 197-211
    • Lieber, C.S.1    DeCarli, L.M.2
  • 18
    • 17844392693 scopus 로고    scopus 로고
    • Comparison of seven methods for producing Affymetrix expression scores based on false discovery rates in disease profiling data
    • Shedden K, Chen W, Kuick R, et al. Comparison of seven methods for producing Affymetrix expression scores based on false discovery rates in disease profiling data. BMC Bioinformatics. 2005;6(1):26.
    • (2005) BMC Bioinformatics , vol.6 , Issue.1 , pp. 26
    • Shedden, K.1    Chen, W.2    Kuick, R.3
  • 19
    • 33745703327 scopus 로고    scopus 로고
    • Molecular classification of papillary thyroid carcinoma: Distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis
    • Giordano TJ, Kuick R, Thomas DG, et al. Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis. Oncogene. 2005;1:10.
    • (2005) Oncogene , vol.1 , pp. 10
    • Giordano, T.J.1    Kuick, R.2    Thomas, D.G.3
  • 20
    • 1542571921 scopus 로고    scopus 로고
    • Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors
    • Szmola R, Kukor Z, Sahin-Toth M. Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors. J Biol Chem. 2003;278(49):48580-48589.
    • (2003) J Biol Chem , vol.278 , Issue.49 , pp. 48580-48589
    • Szmola, R.1    Kukor, Z.2    Sahin-Toth, M.3
  • 21
    • 0018238473 scopus 로고
    • Multicenter survey of the etiology of pancreatic diseases. Relationship between the relative risk of developing chronic pancreatitis and alcohol, protein and lipid consumption
    • Durbec JP, Sarles H. Multicenter survey of the etiology of pancreatic diseases. Relationship between the relative risk of developing chronic pancreatitis and alcohol, protein and lipid consumption. Digestion. 1978;18(337):350.
    • (1978) Digestion , vol.18 , Issue.337 , pp. 350
    • Durbec, J.P.1    Sarles, H.2
  • 22
    • 0002534064 scopus 로고
    • The pancreas
    • Sabiston DC, ed. Philadelphia: Saunders
    • Yeo CJ, Cameron JL. The pancreas. In: Sabiston DC, ed. Textbook of Surgery, 14th ed. Philadelphia: Saunders; 1991:1076-1107.
    • (1991) Textbook of Surgery, 14th Ed. , pp. 1076-1107
    • Yeo, C.J.1    Cameron, J.L.2
  • 23
    • 0028890034 scopus 로고
    • Effect of chronic ethanol feeding on digestive enzyme synthesis and mRNA content in rat pancreas
    • Perkins PS, Rutherford RE, Pandol SJ. Effect of chronic ethanol feeding on digestive enzyme synthesis and mRNA content in rat pancreas. Pancreas. 1995;10(1):14-21.
    • (1995) Pancreas , vol.10 , Issue.1 , pp. 14-21
    • Perkins, P.S.1    Rutherford, R.E.2    Pandol, S.J.3
  • 24
    • 21444453418 scopus 로고    scopus 로고
    • Human mesotrypsin defies natural trypsin inhibitors: From passive resistance to active destruction
    • Sahin-Toth M. Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction. Protein Pept Lett. 2005;12(5):457-464.
    • (2005) Protein Pept Lett , vol.12 , Issue.5 , pp. 457-464
    • Sahin-Toth, M.1
  • 25
    • 15744392747 scopus 로고    scopus 로고
    • Transgenic expression of pancreatic secretory trypsin inhibitor-1 ameliorates secretagogue-induced pancreatitis in mice
    • Nathan JD, Romac J, Peng RY, et al. Transgenic expression of pancreatic secretory trypsin inhibitor-1 ameliorates secretagogue-induced pancreatitis in mice. Gastroenterology. 2005;128(3):717-727.
    • (2005) Gastroenterology , vol.128 , Issue.3 , pp. 717-727
    • Nathan, J.D.1    Romac, J.2    Peng, R.Y.3
  • 27
    • 1642458354 scopus 로고    scopus 로고
    • Activation transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response
    • Jiang HY, Wek SA, McGrath BC, et al. Activation transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response. Mol Cell Biol. 2004;14(3):1365-1377.
    • (2004) Mol Cell Biol , vol.14 , Issue.3 , pp. 1365-1377
    • Jiang, H.Y.1    Wek, S.A.2    McGrath, B.C.3
  • 28
    • 17044387386 scopus 로고    scopus 로고
    • Hsp70 chaperones: Cellular functions and molecular mechanism
    • Mayer MP, Bukau B. Hsp70 chaperones: cellular functions and molecular mechanism. Cell Mol Life Sci. 2005;62(6):670-684.
    • (2005) Cell Mol Life Sci , vol.62 , Issue.6 , pp. 670-684
    • Mayer, M.P.1    Bukau, B.2
  • 29
    • 0036143683 scopus 로고    scopus 로고
    • Thermal stress-induced HSP70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats
    • Bhagat L, Singh VP, Song AM, et al. Thermal stress-induced HSP70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats. Gastroenterology. 2002;122(1):156-165.
    • (2002) Gastroenterology , vol.122 , Issue.1 , pp. 156-165
    • Bhagat, L.1    Singh, V.P.2    Song, A.M.3
  • 30
    • 0033574789 scopus 로고    scopus 로고
    • Control of mRNA decay by heat-shock-ubiquitin-proteasome pathway
    • Laroia G, Cuesta R, Brewer G, et al. Control of mRNA decay by heat-shock-ubiquitin-proteasome pathway. Science. 1999;284:499-502.
    • (1999) Science , vol.284 , pp. 499-502
    • Laroia, G.1    Cuesta, R.2    Brewer, G.3
  • 31
    • 3242720733 scopus 로고    scopus 로고
    • Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis
    • Kubisch C, DiMagno MJ, Tietz AB, et al. Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. Gastroenterology. 2004;127(1):275-286.
    • (2004) Gastroenterology , vol.127 , Issue.1 , pp. 275-286
    • Kubisch, C.1    DiMagno, M.J.2    Tietz, A.B.3
  • 32
    • 0141805544 scopus 로고    scopus 로고
    • Stressed to death: Regulation of apoptotic signalling pathways by the heat shock proteins
    • Beere HM. Stressed to death: regulation of apoptotic signalling pathways by the heat shock proteins. Sci STKE. 2001;93:1-6.
    • (2001) Sci STKE , vol.93 , pp. 1-6
    • Beere, H.M.1
  • 33
    • 0037246247 scopus 로고    scopus 로고
    • On the role of Hsp27 in regulating apoptosis
    • Concannon CG, Gorman AM, Samali A. On the role of Hsp27 in regulating apoptosis. Apoptosis. 2003;8(1):61-70.
    • (2003) Apoptosis , vol.8 , Issue.1 , pp. 61-70
    • Concannon, C.G.1    Gorman, A.M.2    Samali, A.3
  • 34
    • 0033796051 scopus 로고    scopus 로고
    • Inhibition of DAXX-mediated apoptosis by heat shock protein 27
    • Charette SJ, Lavoie JN, Lambert H, et al. Inhibition of DAXX-mediated apoptosis by heat shock protein 27. Mol Cell Biol. 2000;20:7602-7612.
    • (2000) Mol Cell Biol , vol.20 , pp. 7602-7612
    • Charette, S.J.1    Lavoie, J.N.2    Lambert, H.3
  • 35
    • 20444417280 scopus 로고    scopus 로고
    • Apoptosis of pancreatic cells in acute pancreatitis: Is it good or bad?
    • Bhatia M. Apoptosis of pancreatic cells in acute pancreatitis: is it good or bad? J Cell Mol Med. 2004;8(3):402-409.
    • (2004) J Cell Mol Med , vol.8 , Issue.3 , pp. 402-409
    • Bhatia, M.1
  • 36
    • 11844301338 scopus 로고    scopus 로고
    • Cell death pathways in pancreatitis and pancreatic cancer
    • Gukovskaya AS, Pandol SJ. Cell death pathways in pancreatitis and pancreatic cancer. Pancreatology. 2004;4(6):567-586.
    • (2004) Pancreatology , vol.4 , Issue.6 , pp. 567-586
    • Gukovskaya, A.S.1    Pandol, S.J.2
  • 37
    • 0033744530 scopus 로고    scopus 로고
    • Comparison of reg I and reg III levels during acute pancreatitis in the rat
    • Zenilman ME, Tuchman D, Zheng Q, et al. Comparison of reg I and reg III levels during acute pancreatitis in the rat. Ann Surg. 2000;232:646-652.
    • (2000) Ann Surg , vol.232 , pp. 646-652
    • Zenilman, M.E.1    Tuchman, D.2    Zheng, Q.3
  • 38
    • 4544289943 scopus 로고    scopus 로고
    • Targeted inhibition of gene expression of pancreatitis-associated proteins exacerbates the severity of acute pancreatitis in rats
    • Zhang H, Kandil E, Lin YY, et al. Targeted inhibition of gene expression of pancreatitis-associated proteins exacerbates the severity of acute pancreatitis in rats. Scand J Gastroenterol. 2004;39(9):870-881.
    • (2004) Scand J Gastroenterol , vol.39 , Issue.9 , pp. 870-881
    • Zhang, H.1    Kandil, E.2    Lin, Y.Y.3
  • 39
    • 33745731360 scopus 로고    scopus 로고
    • Anti-inflammative effects of pancreatic associated protein in inflammatory bowel disease
    • Giromella M, Iovanna JL, Sans M, et al. Anti-inflammative effects of pancreatic associated protein in inflammatory bowel disease. Gut. 2005:1-17.
    • (2005) Gut , pp. 1-17
    • Giromella, M.1    Iovanna, J.L.2    Sans, M.3
  • 41
    • 0030845535 scopus 로고    scopus 로고
    • Metallothionein in physiological and pathophysiological processes
    • Moffatt P, Denzizeau F. Metallothionein in physiological and pathophysiological processes. Drug Metab Rev. 1997;29:261-307.
    • (1997) Drug Metab Rev , vol.29 , pp. 261-307
    • Moffatt, P.1    Denzizeau, F.2
  • 42
    • 0042563126 scopus 로고    scopus 로고
    • Chronic intragastric alcohol exposure causes hypoxia and oxidative stress in the rat pancreas
    • McKim SE, Uesugi T, Raleigh JA, et al. Chronic intragastric alcohol exposure causes hypoxia and oxidative stress in the rat pancreas. Arch Biochem Biophys. 2003;417:34-43.
    • (2003) Arch Biochem Biophys , vol.417 , pp. 34-43
    • McKim, S.E.1    Uesugi, T.2    Raleigh, J.A.3
  • 43
    • 0031687147 scopus 로고    scopus 로고
    • Metallothionein protects against cerulein-induced acute pancreatitis: Analysis using transgenic mice
    • Fu K, Tomita T, Sarras MP Jr, et al. Metallothionein protects against cerulein-induced acute pancreatitis: analysis using transgenic mice. Pancreas. 1998;17(3):238-246.
    • (1998) Pancreas , vol.17 , Issue.3 , pp. 238-246
    • Fu, K.1    Tomita, T.2    Sarras Jr., M.P.3
  • 44
    • 1242272746 scopus 로고    scopus 로고
    • SLC19: The folate/thiamine transporter family
    • Ganapathy V, Smith SB, Prasad PD. SLC19: the folate/thiamine transporter family. Eur J Physiol. 2004;447:641-646.
    • (2004) Eur J Physiol , vol.447 , pp. 641-646
    • Ganapathy, V.1    Smith, S.B.2    Prasad, P.D.3
  • 45
    • 0027982946 scopus 로고
    • Tissue distribution of glycine N-methyltransferase, a major folate-binding protein of liver
    • Yeo EJ, Wagner C. Tissue distribution of glycine N-methyltransferase, a major folate-binding protein of liver. Proc Natl Acad Sci U S A. 1994;91(1):210-214.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.1 , pp. 210-214
    • Yeo, E.J.1    Wagner, C.2
  • 46
    • 0028832026 scopus 로고
    • Folate deficiency inhibits pancreatic amylase secretion in rats
    • Balanghi M, Wagner C. Folate deficiency inhibits pancreatic amylase secretion in rats. Am J Clin Nutr. 1995;61(1):90-96.
    • (1995) Am J Clin Nutr , vol.61 , Issue.1 , pp. 90-96
    • Balanghi, M.1    Wagner, C.2
  • 47
    • 0031239318 scopus 로고    scopus 로고
    • Pancreatic exocrine secretion is blocked by inhibitors of methylation
    • Capdevila A, Decha-Umphai W, Song KH, et al. Pancreatic exocrine secretion is blocked by inhibitors of methylation. Arch Biochem Biophys. 1997;345(1):47-55.
    • (1997) Arch Biochem Biophys , vol.345 , Issue.1 , pp. 47-55
    • Capdevila, A.1    Decha-Umphai, W.2    Song, K.H.3
  • 48
    • 0036328451 scopus 로고    scopus 로고
    • Abnormal methyl metabolism in pancreatic toxicity and diabetes
    • Longnecker DS. Abnormal methyl metabolism in pancreatic toxicity and diabetes. J Nutr. 2002;132(8):2373S-2376S.
    • (2002) J Nutr , vol.132 , Issue.8
    • Longnecker, D.S.1
  • 49
    • 0026536040 scopus 로고
    • Acute experimental hemorrhagic-necrotizing pancreatitis induced by feeding a choline-deficient, ethionine-supplemented diet. Methodology and standards
    • Niderau C, Luthen R, Niederau MC, et al. Acute experimental hemorrhagic-necrotizing pancreatitis induced by feeding a choline-deficient, ethionine-supplemented diet. Methodology and standards. Eur Surg Res. 1992;24(1):40-54.
    • (1992) Eur Surg Res , vol.24 , Issue.1 , pp. 40-54
    • Niderau, C.1    Luthen, R.2    Niederau, M.C.3
  • 50
    • 84987838539 scopus 로고    scopus 로고
    • Gross and microscopic anatomy of the pancreas
    • von Hoff DD, Evans DB, Hruban RH, eds. Sudbury, MA: Jones & Bartlett;
    • Washington MK. Gross and microscopic anatomy of the pancreas. In: von Hoff DD, Evans DB, Hruban RH, eds. Pancreatic Cancer. Sudbury, MA: Jones & Bartlett; 2005:2-11.
    • (2005) Pancreatic Cancer , pp. 2-11
    • Washington, M.K.1


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