The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress

International Journal of Neuropsychopharmacology

Volumn 16, Issue 9, 2013, Pages 2081-2094

  Sachs, Benjamin D ^a   Rodriguiz, Ramona M ^b   Siesser, William B ^a   Kenan, Alexander ^a   Royer, Elizabeth L ^a   Jacobsen, Jacob P R ^a   Wetsel, William C ^b   Caron, Marc G ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Animal models; anxiety; behavioural science; early life stress; impulsivity; serotonin; tryptophan hydroxylase

Indexed keywords

CORTICOSTERONE; GLYCOGEN SYNTHASE KINASE 3BETA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SEROTONIN; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; TRYPTOPHAN HYDROXYLASE 2;

ACUTE STRESS; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR; BEHAVIOURAL DISINHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; EARLY LIFE STRESS; FEAR; FEMALE; GENE MUTATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMPULSIVENESS; MALE; MATERNAL DEPRIVATION; MATERNAL STRESS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; REDUCTION; SEROTONIN BRAIN LEVEL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE;

AMYGDALA; ANIMALS; ANXIETY; ANXIETY, SEPARATION; BEHAVIOR, ANIMAL; BRAIN; CORTICOSTERONE; DISEASE MODELS, ANIMAL; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; IMMEDIATE-EARLY PROTEINS; IMPULSIVE BEHAVIOR; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; NEUROGENESIS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, N-METHYL-D-ASPARTATE; SEROTONIN; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; TRYPTOPHAN HYDROXYLASE;

EID: 84883361764     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145713000321     Document Type: Article

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