Contrasting roles of basolateral amygdala and orbitofrontal cortex in impulsive choice

Journal of Neuroscience

Volumn 24, Issue 20, 2004, Pages 4718-4722

  Winstanley, Catharine A ^a,b   Theobald, David E H ^a   Cardinal, Rudolf N ^a   Robbins, Trevor W ^a  

^a UK   (United Kingdom)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Amygdala; Cognitive; Delay discounting; Frontal; Goal directed; Impulsivity

Indexed keywords

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN INJURY; COGNITION; CONTROLLED STUDY; EXCITATION; IMPULSIVENESS; MALE; NERVE CELL NETWORK; NEUROPSYCHOLOGY; NONHUMAN; ORBITAL CORTEX; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD;

AMYGDALA; ANIMALS; BEHAVIOR, ANIMAL; CHOICE BEHAVIOR; CONDITIONING, OPERANT; FRONTAL LOBE; IMPULSIVE BEHAVIOR; MALE; RATS; RATS, INBRED STRAINS; REINFORCEMENT (PSYCHOLOGY); REWARD; TIME FACTORS;

EID: 2442651554     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5606-03.2004     Document Type: Article

References (37)

1. Ainslie G (1975) A behavioral theory of impulsiveness and impulse control. Psychol Bull 82:463-498.
2. Baxter MG, Parker A, Lindner CCC, Izquierdo AD, Murray EA (2000) Control of response selection by reinforcer value requires interaction of amygdala and orbital prefrontal cortex. J Neurosci 20:4311-4319.
3. Bechara A, Damasio H, Tranel D, Anderson SW (1998) Dissociation of working memory from decision making within the human prefrontal cortex. J Neurosci 18:428-437.
4. Bechara A, Damasio H, Damasio AR, Lee GP (1999) Different contributions of the human amygdala and ventromedial prefrontal cortex to decision-making. J Neurosci 19:5473-5481.
5. Berendse HW, Galis-de Graaf Y, Groenewegen HJ (1992) Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat. J Comp Neurol 316:314-347.
6. Burns LH, Robbins TW, Everitt BJ (1993) Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions of amphetamine. Behav Brain Res 55:167-183.
7. Cador M, Robbins TW, Everitt BJ (1989) Involvement of the amygdala in stimulus-reward associations: interaction with the ventral striatum. Neuroscience 30:77-86.
8. Cardinal RN, Robbins TW, Everitt BJ (2000) The effects of d-amphetamine, chlordiazepoxide, alpha-flupenthixol and behavioral manipulations on choice of signalled and unsignalled delayed reinforcement in rats. Psychopharmacology 152:362-375.
9. Cardinal RN, Pennicott DR, Sugathapala CL, Robbins TW, Everitt BJ (2001) Impulsive choice induced in rats by lesions of the nucleus accumbens core. Science 292:2499-2501.
10. Cardinal RN, Parkinson JA, Hall J, Everitt BJ (2002) Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex. Neurosci Biobehav Rev 26:321-352.
11. Chudasama Y, Robbins TW (2003) Dissociable contributions of the orbitofrontal and infralimbic cortex to pavlovian autoshaping and discrimination reversal learning: further evidence for the functional heterogeneity of the rodent frontal cortex. J Neurosci 23:8771-8780.
12. Chudasama Y, Passetti F, Rhodes SEV, Lopian D, Desai A, Robbins TW (2003) Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulae, infralimbic and orbitofrontal cortex in the rat: differential effects on selectivity, impulsivity and compulsivity. Behav Brain Res 146:105-119.
13. Damasio AR (1994) Descartes' error. New York: Putman.
14. Evenden JL, Ryan CN (1996) The pharmacology of impulsive behavior in rats: the effects of drugs on response choice with varying delays of reinforcement. Psychopharmacology 128:161-170.
15. Ferry B, Di Scala G (1997) Bicuculline administration into basolateral amygdala facilitates trace conditioning of odor aversion in the rat. Neurobiol Learn Mem 67:80-83.
16. Gallagher M (2000) The amygdala and associative learning. In: The amygdala: a functional analysis, Ed 2 (Aggleton JP, ed), pp 311-330. New York: Oxford UP.
17. Garrud P, Goodall G, Mackintosh NJ (1981) Overshadowing of a stimulus-reinforcer association by an instrumental response. J Exp Psychol 33B:123-135.
18. Jones B, Mishkin M (1972) Limbic lesions and the problem of stimulus-reinforcement associations. Exp Neurol 36:362-377.
19. Krettek JE, Price JL (1977) Projections from the amygdaloid complex to the cerebral cortex and thalamus in the rat and cat. J Comp Neurol 172:687-722.
20. LeDoux JE (2000) The amygdala and emotion: a view through fear. In: The amygdala: a functional analysis, Ed 2 (Aggleton JP, ed), pp 289-310. New York: Oxford UP.
21. Logue AW (1988) Res on self-control-an integrating framework. Behav Brain Sci 11:665-709.
22. McDonald AJ (1991) Organization of amygdaloid projections to the prefrontal cortex and associated striatum in the rat. Neuroscience 44:1-14.
23. Mobini S, Body S, Ho M-Y, Bradshaw CM, Szabadi E, Deakin JFW, Anderson IM (2002) Effects of lesions of the orbitofrontal cortex on sensitivity to delayed and probabilistic reinforcement. Psychopharmacology 160:290-298.
24. Mogenson GJ, Jones DL, Yim CY (1980) From motivation to action: functional interface between the limbic system and the motor system. Prog Neurobiol 14:69-97.
25. Nauta WJH (1971) The problem of the frontal lobe: a reinterpretation. J Psychiat Res 8:167-187.
26. Öngür D, Price JL (2000) The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans. Cereb Cortex 10:206-219.
27. Parkinson JA, Robbins TW, Everitt BJ (2000) Dissociable roles of the central and basolateral amygdala in appetitive emotional learning. Eur J Neurosci 12:405-413.
28. Paxinos G, Watson C (1998) The rat brain in stereotaxic co-ordinates, Ed 4. Sydney: Academic.
29. Pitkänen A (2000) Connectivity of the rat amygdaloid complex. In: The amygdala: a functional analysis, Ed 2 (Aggleton JP, ed), pp 31-116. New York: Oxford UP.
30. Robbins TW (1996) Dissociating executive functions of the prefrontal cortex. Phil Trans R Soc Lond B Biol Sci 351:1463-1471.
31. Rogers RD, Everitt BJ, Baldacchino A, Blackshaw AJ, Swainson R, Wynne K, Baker NB, Hunter J, Carthy T, Booker E, London M, Deakin JFW, Sahakian BJ, Robbins TW (1999) Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: evidence for monoaminergic mechanisms. Neuropsychopharmacol 20:322-339.
32. Schoenbaum G, Chiba AA, Gallagher M (1999) Neural encoding in orbitofrontal cortex and basolateral amygdala during olfactory discrimination learning. J Neurosci 19:1876-1884.
33. Schoenbaum G, Chiba AA, Gallagher M (2000) Changes in functional connectivity in orbitofrontal cortex and basolateral amygdala during learning and reversal learning. J Neurosci 20:5179-5189.
34. Schoenbaum G, Setlow B, Ramus SJ (2003a) A systems approach to orbitofrontal cortex function: recordings in rat orbitofrontal cortex reveal interactions with different learning systems. Behav Brain Res 146:19-29.
35. Schoenbaum G, Setlow B, Saddoris MP, Gallagher M (2003b) Encoding predicted outcome and acquired value in orbitofrontal cortex during cue sampling depends upon input from basolateral amygdala. Neuron 39:855-867.
36. Setlow B, Holland PC, Gallagher M (2002) Disconnection of the basolateral amygdala complex and nucleus accumbens impairs Pavlovian second-order conditioned responses. Behav Neurosci 116:267-275.
37. Wallis JD, Miller EK (2003) Neuronal activity in primate dorsolateral and orbital prefrontal cortex during performance of a reward preference task Eur J Neurosci 18:2069-2081.