Aldosterone acutely stimulates NCC activity via a SPAK-mediated pathway

American Journal of Physiology - Renal Physiology

Volumn 305, Issue 5, 2013, Pages

  Ko, Benjamin ^a   Mistry, Abinash C ^b   Hanson, Lauren ^a   Mallick, Rickta ^b   Wynne, Brandi M ^b   Thai, Tiffany L ^b   Bailey, James L ^b   Klein, Janet D ^b,d   Hoover, Robert S ^b,c,d  

^a UNIVERSITY OF CHICAGO   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Atlanta Veterans Affairs Medical Center   (Georgia)

^d EMORY UNIVERSITY   (United States)

Author keywords

Aldosterone; NCC; SPAK; WNK4

Indexed keywords

ALDOSTERONE; PROTEIN KINASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM CHLORIDE COTRANSPORTER; STE20 SPS 1 RELATED PROLINE ALANINE RICH KINASE; UNCLASSIFIED DRUG; IMMEDIATE EARLY PROTEIN; MINERALOCORTICOID RECEPTOR; PAS DOMAIN KINASES; PROTEIN SERINE THREONINE KINASE; SERUM-GLUCOCORTICOID REGULATED KINASE; SLC12A3 PROTEIN, MOUSE;

ALDOSTERONE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; CELL LINE; CELL SURFACE; CONTROLLED STUDY; DRUG EFFECT; GENE SILENCING; HYPERTENSION; IMMUNOBLOTTING; KIDNEY CORTEX; KIDNEY DISEASE; KIDNEY DISTAL TUBULE; LONG TERM EXPOSURE; MINIPUMP; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SODIUM ABSORPTION; SODIUM BALANCE; SODIUM RESTRICTION; ADRENALECTOMY; ANIMAL; CELL CULTURE; DRUG EFFECTS; MALE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADRENALECTOMY; ALDOSTERONE; ANIMALS; CELLS, CULTURED; IMMEDIATE-EARLY PROTEINS; MALE; MICE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MINERALOCORTICOID; SODIUM CHLORIDE SYMPORTERS; SOLUTE CARRIER FAMILY 12, MEMBER 3;

EID: 84883347283     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00053.2013     Document Type: Article

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