Time course of pain sensation in rat models of insulin resistance, type 2 diabetes, and exogenous hyperinsulinaemia

Diabetes/Metabolism Research and Reviews

Volumn 24, Issue 8, 2008, Pages 642-650

  Sugimoto, Kazuhiro ^a   Rashid, Irena B ^a   Kojimaa, Keiya ^a   Shoji, Masaru ^a   Tanabe, Jutaro ^a   Tamasawa, Naoki ^a   Suda, Toshihiro ^a   Yasujima, Minoru ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Adipokines; Behavioural test; Hyperinsulinaemia; Insulin resistance; Nociception; Small sensory fibre neuropathy

Indexed keywords

ADIPOCYTOKINE; CHOLESTEROL; INSULIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; HYPERALGESIA; HYPERINSULINEMIA; HYPOALGESIA; INSULIN RELEASE; INSULIN RESISTANCE; MALE; MECHANICAL STIMULATION; NOCICEPTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WISTAR RAT; ZUCKER DIABETIC FATTY RAT; ZUCKER RAT; ANIMAL; BLOOD; BODY WEIGHT; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERINSULINISM; METABOLISM; OBESITY; PAIN; PAIN ASSESSMENT; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; HYPERGLYCEMIA; HYPERINSULINISM; INSULIN RESISTANCE; MALE; OBESITY; PAIN; PAIN MEASUREMENT; RATS; RATS, ZUCKER; THINNESS;

EID: 60849098222     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.903     Document Type: Article

References (48)

1. Franklin GM, Kahn LB, Baxter J, Marshall JA, Hamman RF, The San Luis Valley Diabetes Study. Sensory neuropathy in non-insulin-dependent diabetes mellitus. Am J Epidemiol 1990; 131: 633-643.
2. Ellenberg M. Diabetic neuropathy presenting as the initial clinical manifestation of diabetes. Ann Intern Med 1958; 49: 620-631.
3. de Neeling JN, Beks PJ, Bertelsmann FW, Heine RJ, Bouter LM. Peripheral somatic nerve function in relation to glucose tolerance in an elderly Caucasian population: the Hoorn study. Diabet Med 1996; 13: 960-966.
4. Novella SP, Inzucchi SE, Goldstein JM. The frequency of undiagnosed diabetes and impaired glucose tolerance in patients with idiopathic sensory neuropathy. Muscle Nerve 2001; 24: 1229-1231.
5. Singleton JR, Smith AG, Bromberg MB. Painful sensory polyneuropathy associated with impaired glucose tolerance. Muscle Nerve 2001; 24: 1225-1228.
6. Singleton JR, Smith AG, Bromberg MB. Increased prevalence of impaired glucose tolerance in patients with painful sensory neuropathy. Diabetes Care 2001; 24: 1448-1453.
7. Sumner CJ, Sheth S, Griffin JW, Cornblath DR, Polydefkis M. The spectrum of neuropathy in diabetes and impaired glucose tolerance. Neurology 2003; 60: 108-111.
8. Smith AG, Ramachandran P, Tripp S, Singleton JR. Epidermal nerve innervation in impaired glucose tolerance and diabetes-associated neuropathy. Neurology 2001; 57: 1701-1704.
9. Guy RJ, Clark CA, Malcolm PN, Watkins PJ. Evaluation of thermal and vibration sensation in diabetic neuropathy. Diabetologia 1985; 28: 131-137.
10. Umapathi T, Tan WL, Loke SC, Soon PC, Tavintharan S, Chan YH. Intraepidermal nerve fiber density as a marker of early diabetic neuropathy. Muscle Nerve 2007; 35: 591-598.
11. Gordon Smith A, Robinson Singleton J. Idiopathic neuropathy, prediabetes and the metabolic syndrome. J Neurol Sci 2006; 242: 9-14.
12. Dyck PJ, Klein CJ, Weigand SD. Does impaired glucose metabolism cause polyneuropathy? Review of previous studies and design of a prospective controlled population-based study. Muscle Nerve 2007; 36: 536-541.
13. Daskalopoulou SS, Athyros VG, Kolovou GD, Anagnostopoulou KK, Mikhailidis DP. Definitions of metabolic syndrome: Where are we now? Curr Vasc Pharmacol 2006; 4: 185-197.
14. Zimmet P, Boyko EJ, Collier GR, de Courten M. Etiology of the metabolic syndrome: potential role of insulin resistance, leptin resistance, and other players. Ann N Y Acad Sci 1999; 892: 25-44.
15. Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 2006; 116: 1784-1792.
16. Hughes RA, Umapathi T, Gray IA, et al. A controlled investigation of the cause of chronic idiopathic axonal polyneuropathy. Brain 2004; 127: 1723-1730.
17. Smith AG, Russell J, Feldman EL, et al. Lifestyle intervention for pre-diabetic neuropathy. Diabetes Care 2006; 29: 1294-1299.
18. Kamiya H, Murakawa Y, Zhang W, Sima AA. Unmyelinated fiber sensory neuropathy differs in type 1 and type 2 diabetes. Diabetes Metab Res Rev 2005; 21: 448-458.
19. Frisbee JC, Delp MD. Vascular function in the metabolic syndrome and the effects on skeletal muscle perfusion: lessons from the obese Zucker rat. Essays Biochem 2006; 42: 145-161.
20. Naruse K, Rask-Madsen C, Takahara N, et al. Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance. Diabetes 2006; 55: 691-698.
21. Srinivasan K, Ramarao P. Animal models in type 2 diabetes research: an overview. Indian J Med Res 2007; 125: 451-472.
22. Tokuyama Y, Sturis J, DePaoli AM, et al. Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes 1995; 44: 1447-1457.
23. Shafrir E. Animal models of non-insulin-dependent diabetes. Diabetes Metab Rev 1992; 8: 179-208.
24. Phillips MS, Liu Q, Hammond HA, et al. Leptin receptor missense mutation in the fatty Zucker rat. Nat Genet 1996; 13: 18-19.
25. Heidenreich KA, de Vellis G, Gilmore PR. Functional properties of the subtype of insulin receptor found on neurons. J Neurochem 1988; 51: 878-887.
26. Fernyhough P, Willars GB, Lindsay RM, Tomlinson DR. Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones. Brain Res 1993; 607: 117-124.
27. Recio-Pinto E, Rechler MM, Ishii DN. Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons. J Neurosci 1986; 6: 1211-1219.
28. Sugimoto K, Murakawa Y, Zhang W, Xu G, Sima AAF. Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms. Diabetes Metab Res Rev 2000; 16: 354-363.
29. Sugimoto K, Murakawa Y, Sima AAF. Expression and localization of insulin receptor in rat dorsal root ganglion and spinal cord. J Peripher Nerv Syst 2002; 7: 44-53.
30. Sugimoto K, Baba M, Suda T, Yasujima M, Yagihashi S. Peripheral neuropathy and microangiopathy in rats with insulinoma: association with chronic hyperinsulinemia. Diabetes Metab Res Rev 2003; 19: 392-400.
31. Galipeau DM, Yao L, McNeill JH. Relationship among hyperinsulinemia, insulin resistance, and hypertension is dependent on sex. Am J Physiol Heart Circ Physiol 2002; 283: H562-H567.
32. Podjarny E, Bernheim J, Katz B, Green J, Mekler J, Bursztyn M. Chronic exogenous hyperinsulinemia in pregnancy: a rat model of pregnancy-induced hypertension. J Am Soc Nephrol 1998; 9: 9-13.
33. Kashiwagi A, Shinozaki K, Nishio Y, et al. Endothelium-specific activation of NAD(P)H oxidase in aortas of exogenously hyperinsulinemic rats. Am J Physiol 1999; 277: E976-E983.
34. Roane DS, Porter JR. Nociception and opioid-induced analgesia in lean (Fa/-) and obese (fa/fa) Zucker rats. Physiol Behav 1986; 38: 215-218.
35. Piercy V, Banner SE, Bhattacharyya A, et al. Thermal, but not mechanical, nociceptive behavior is altered in the Zucker Diabetic Fatty rat and is independent of glycemic status. J Diabetes Complications 1999; 13: 163-169.
36. Miyasaka K, Nomoto S, Ohta M, et al. Disturbance of response to acute thermal pain in naturally occurring cholecystokinin-a receptor gene knockout Otsuka Long-Evans Tokushima Fatty (OLETF) rats. J Pharmacol Sci 2006; 101: 280-285.
37. Kamenov Z, Higashino H, Todorova M, Kajimoto N, Suzuki A. Physiological characteristics of diabetic neuropathy in sucrosefed Otsuka Long-Evans Tokushima fatty rats. Methods Find Exp Clin Pharmacol 2006; 28: 13-18.
38. Ishida K, Mizuno A, Min Z, Sano T, Shima K. Which is the primary etiologic event in Otsuka Long-Evans Tokushima Fatty rats, a model of spontaneous non-insulin-dependent diabetes mellitus, insulin resistance, or impaired insulin secretion? Metabolism 1995; 44: 940-945.
39. Zhuang HX, Wuarin L, Fei ZJ, Ishii DN. Insulin-like growth factor (IGF) gene expression is reduced in neural tissues and liver from rats with non-insulin-dependent diabetes mellitus, and IGF treatment ameliorates diabetic neuropathy. J Pharmacol Exp Ther 1997; 283: 366-374.
40. Hoybergs YM, Meert TF. The effect of low-dose insulin on mechanical sensitivity and allodynia in type I diabetes neuropathy. Neurosci Lett 2007; 417: 149-154.
41. Romanovsky D, Cruz NF, Dienel GA, Dobretsov M. Mechanical hyperalgesia correlates with insulin deficiency in normoglycemic streptozotocin-treated rats. Neurobiol Dis 2006; 24: 384-394.
42. Sugimoto K, Rashid IB, Shoji M, Suda T, Yasujima M. Early changes in insulin receptor signaling and pain sensation in streptozotocin-induced diabetic neuropathy in rats. J Pain 2008; 9: 237-245.
43. Dobretsov M, Romanovsky D, Stimers JR. Early diabetic neuropathy: triggers and mechanisms. World J Gastroenterol 2007; 13: 175-191.
44. Oana F, Takeda H, Hayakawa K, et al. Physiological difference between obese (fa/fa) Zucker rats and lean Zucker rats concerning adiponectin. Metabolism 2005; 54: 995-1001.
45. Yang B, Brown KK, Chen L, et al. Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats. BMC Pharmacol 2004; 4: 23.
46. Kadowaki T, Yamauchi T, Kubota N. The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS. FEBS Lett 2008; 582: 74-80.
47. Kihara M, Zollman PJ, Smithson IL, Lagerlund TD, Low PA. Hypoxic effect of exogenous insulin on normal and diabetic peripheral nerve. Am J Physiol 1994; 266: E980-E985.
48. Singhal A, Cheng C, Sun H, Zochodne DW. Near nerve local insulin prevents conduction slowing in experimental diabetes. Brain Res 1997; 763: 209-214.