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Volumn 106, Issue 1-2, 2013, Pages 83-91

Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters

Author keywords

Antiepileptic action; Dehydroepiandrosterone; Glutamate transporters; Iron induced epilepsy; MRNA expression; Post traumatic epilepsy

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER 1; FERRIC CHLORIDE; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; MESSENGER RNA; PRASTERONE;

EID: 84883288907     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2013.06.008     Document Type: Article
Times cited : (22)

References (55)
  • 1
    • 0031562362 scopus 로고    scopus 로고
    • Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats
    • Akbar M.T., Torp R., Danbolt N.C., Levy L.M., Meldrum B.S., Ottersen O.P. Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats. Neuroscience 1997, 78:351-359.
    • (1997) Neuroscience , vol.78 , pp. 351-359
    • Akbar, M.T.1    Torp, R.2    Danbolt, N.C.3    Levy, L.M.4    Meldrum, B.S.5    Ottersen, O.P.6
  • 2
    • 0033755119 scopus 로고    scopus 로고
    • Dehydroepiandrosterone prevents oxidation injury induced by transient ischemia/reperfusion in the brain of diabetic rats
    • Aragno M., Parole S., Brignardello E., Mauro M., Tamagno E., Manti R., Danni O., Boccuzzi G. Dehydroepiandrosterone prevents oxidation injury induced by transient ischemia/reperfusion in the brain of diabetic rats. Diabetes 2000, 49:1924-1931.
    • (2000) Diabetes , vol.49 , pp. 1924-1931
    • Aragno, M.1    Parole, S.2    Brignardello, E.3    Mauro, M.4    Tamagno, E.5    Manti, R.6    Danni, O.7    Boccuzzi, G.8
  • 3
    • 0002611769 scopus 로고
    • Effects of ovarian steroid hormones on brain excitability and their relation to epilepsy seizure variation during the menstrual cycle
    • Backstrom T., Landgren A., Zetterlund, Blom S., Dubrovsky B., Bixo M., Sodergard H. Effects of ovarian steroid hormones on brain excitability and their relation to epilepsy seizure variation during the menstrual cycle. Adv. Epileptol. 1984, 15:269-277.
    • (1984) Adv. Epileptol. , vol.15 , pp. 269-277
    • Backstrom, T.1    Landgren, A.2    Zetterlund Blom, S.3    Dubrovsky, B.4    Bixo, M.5    Sodergard, H.6
  • 4
    • 0033586349 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage
    • Bastianetto S., Ramassamy C., Poirier J., Quirion R. Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. Mol. Brain Res. 1999, 66:35-41.
    • (1999) Mol. Brain Res. , vol.66 , pp. 35-41
    • Bastianetto, S.1    Ramassamy, C.2    Poirier, J.3    Quirion, R.4
  • 5
    • 0029992644 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and dehydroepiandrosterone sulphate as neuroactive neurosteroids
    • Baulieu E., Robel E.P. Dehydroepiandrosterone and dehydroepiandrosterone sulphate as neuroactive neurosteroids. J. Endocrinol. 1996, 150:221-239.
    • (1996) J. Endocrinol. , vol.150 , pp. 221-239
    • Baulieu, E.1    Robel, E.P.2
  • 7
    • 0030010448 scopus 로고    scopus 로고
    • Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors
    • Bergeron R., Montigny C., Debonnel G. Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. J. Neurosci. 1996, 16:1193-1202.
    • (1996) J. Neurosci. , vol.16 , pp. 1193-1202
    • Bergeron, R.1    Montigny, C.2    Debonnel, G.3
  • 9
    • 0033988814 scopus 로고    scopus 로고
    • Mapping of progressive metabolic changes occurring during the development of hippocampal sclerosis in a model of mesial temporal lobe epilepsy
    • Bouilleret V., Boyet S., Marescaux C., Nehlig A. Mapping of progressive metabolic changes occurring during the development of hippocampal sclerosis in a model of mesial temporal lobe epilepsy. Brain Res. 2000, 852:255-262.
    • (2000) Brain Res. , vol.852 , pp. 255-262
    • Bouilleret, V.1    Boyet, S.2    Marescaux, C.3    Nehlig, A.4
  • 10
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 12
    • 84883269193 scopus 로고    scopus 로고
    • Neuroprotective and neurogenic properties of dehydroepiandrosterone and its synthetic analogs
    • Wiley-VCH Verlag Gmbh Co K GaA, Weinheim, A.G. Gravanis, S.H. Mellon (Eds.)
    • Charalampopoulos I., Lazaridis I., Gravanis A. Neuroprotective and neurogenic properties of dehydroepiandrosterone and its synthetic analogs. Hormone in Neurodegeneration, Neuroprotection, and Neurogenesis 2011, 137-154. Wiley-VCH Verlag Gmbh Co K GaA, Weinheim. A.G. Gravanis, S.H. Mellon (Eds.).
    • (2011) Hormone in Neurodegeneration, Neuroprotection, and Neurogenesis , pp. 137-154
    • Charalampopoulos, I.1    Lazaridis, I.2    Gravanis, A.3
  • 14
    • 11244353255 scopus 로고    scopus 로고
    • Progression from frontal-parietal to mesial temporal lobe epilepsy after fluid percussion injury in the rat
    • D'Ambrosio R., Fender J.S., Fairbanks J.P., Simon E.A., Born D.E., Doyle D.L., Miller J.W. Progression from frontal-parietal to mesial temporal lobe epilepsy after fluid percussion injury in the rat. Brain 2005, 128:174-188.
    • (2005) Brain , vol.128 , pp. 174-188
    • D'Ambrosio, R.1    Fender, J.S.2    Fairbanks, J.P.3    Simon, E.A.4    Born, D.E.5    Doyle, D.L.6    Miller, J.W.7
  • 17
    • 0025918575 scopus 로고
    • 2+ channel current in freshly isolated hippocampal CA1 neurons
    • 2+ channel current in freshly isolated hippocampal CA1 neurons. Eur. J. Pharmacol. 1991, 202:269-272.
    • (1991) Eur. J. Pharmacol. , vol.202 , pp. 269-272
    • French Mullen, J.M.1    Spence, K.T.2
  • 18
    • 53049108463 scopus 로고    scopus 로고
    • Hormonal influence on seizures: basic neurobiology
    • Frye C.A. Hormonal influence on seizures: basic neurobiology. Int. Rev. Neurobiol. 2008, 83:27-77.
    • (2008) Int. Rev. Neurobiol. , vol.83 , pp. 27-77
    • Frye, C.A.1
  • 19
    • 0031870605 scopus 로고    scopus 로고
    • Androgenic neurosteroids: anti-seizure effects in animal model of epilepsy
    • Frye C.A., Reed T.A.W. Androgenic neurosteroids: anti-seizure effects in animal model of epilepsy. Psychoneuroendocrinology 1998, 23:385-399.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 385-399
    • Frye, C.A.1    Reed, T.A.W.2
  • 20
    • 0021339969 scopus 로고
    • Changes in the amino acid content of nerve endings (synaptosomes) induced by drugs that alter the metabolism of glutamate and γ-aminobutyric acid
    • Geddes J.W., Wood J.D. Changes in the amino acid content of nerve endings (synaptosomes) induced by drugs that alter the metabolism of glutamate and γ-aminobutyric acid. J. Neurochem. 1984, 42:16-24.
    • (1984) J. Neurochem. , vol.42 , pp. 16-24
    • Geddes, J.W.1    Wood, J.D.2
  • 21
    • 0028833252 scopus 로고
    • Mapping of limbic seizure progressions utilizing the electrogenic status epilepticus model and the 14 C-2-deoxyglucose method
    • Handforth A., Ackermann R.F. Mapping of limbic seizure progressions utilizing the electrogenic status epilepticus model and the 14 C-2-deoxyglucose method. Brain Res. Rev. 1995, 20:1-23.
    • (1995) Brain Res. Rev. , vol.20 , pp. 1-23
    • Handforth, A.1    Ackermann, R.F.2
  • 22
    • 0031944515 scopus 로고    scopus 로고
    • Testosterone versus testosterone and testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism
    • Herzog A.G., Klein P., Jacobs A.R. Testosterone versus testosterone and testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism. Neurology 1998, 50:782-784.
    • (1998) Neurology , vol.50 , pp. 782-784
    • Herzog, A.G.1    Klein, P.2    Jacobs, A.R.3
  • 23
    • 18144374519 scopus 로고    scopus 로고
    • The effect of dehydroepiandrosterone sulphate and allopregnanolone sulfate on the binding of [(3)H] ifenprodil to N-methyl-d-aspartate receptor in rat frontal cortex membrane
    • Johansson T., Le Greve's P. The effect of dehydroepiandrosterone sulphate and allopregnanolone sulfate on the binding of [(3)H] ifenprodil to N-methyl-d-aspartate receptor in rat frontal cortex membrane. J. Steroid Biochem. Mol. Biol. 2005, 94:263-266.
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.94 , pp. 263-266
    • Johansson, T.1    Le Greve's, P.2
  • 24
    • 34047228583 scopus 로고    scopus 로고
    • Epilepsy in the elderly: scope of the life problem
    • Leppik I.E. Epilepsy in the elderly: scope of the life problem. Int. Rev. Neurobiol. 2007, 81:1-14.
    • (2007) Int. Rev. Neurobiol. , vol.81 , pp. 1-14
    • Leppik, I.E.1
  • 25
    • 0000068602 scopus 로고
    • L-Glutamine and l-glutamate: UV method with glutaminase and glutamate dehydrogenase
    • VCH, Verlagsgesellschaft, Weinhein
    • Lund P. l-Glutamine and l-glutamate: UV method with glutaminase and glutamate dehydrogenase. Methods in Enzymatic Analysis 1986, Vol. 8:357-363. VCH, Verlagsgesellschaft, Weinhein.
    • (1986) Methods in Enzymatic Analysis , vol.8 , pp. 357-363
    • Lund, P.1
  • 26
    • 0032007328 scopus 로고    scopus 로고
    • Modification of ion homeostasis by lipid peroxidation: role in neuronal degeneration and adaptive plasticity
    • Mattson M.P. Modification of ion homeostasis by lipid peroxidation: role in neuronal degeneration and adaptive plasticity. Trends Neurosci. 1998, 21:53-57.
    • (1998) Trends Neurosci. , vol.21 , pp. 53-57
    • Mattson, M.P.1
  • 27
    • 0030951630 scopus 로고    scopus 로고
    • Neuroprotective and anti-amnesic potentials of sigma receptor ligands. Prog. Neurol. Psychopharmacol
    • Maurice T., Lockhart B.P. Neuroprotective and anti-amnesic potentials of sigma receptor ligands. Prog. Neurol. Psychopharmacol. Biol. Psychiatry 1997, 21:69-102.
    • (1997) Biol. Psychiatry , vol.21 , pp. 69-102
    • Maurice, T.1    Lockhart, B.P.2
  • 28
    • 0032756551 scopus 로고    scopus 로고
    • Neuroactive neurosteroids as endogenous effectors for sigma1 receptor: pharamocological evidence and therapeutic opportunities
    • Maurice T., Phan V.L., Urani A., Kamei H., Noda Y., Nabeshima T. Neuroactive neurosteroids as endogenous effectors for sigma1 receptor: pharamocological evidence and therapeutic opportunities. Jpn. J. Pharmacol 1999, 81:125-155.
    • (1999) Jpn. J. Pharmacol , vol.81 , pp. 125-155
    • Maurice, T.1    Phan, V.L.2    Urani, A.3    Kamei, H.4    Noda, Y.5    Nabeshima, T.6
  • 29
    • 78649904631 scopus 로고    scopus 로고
    • Antiepileptic action of exogenous dehydroepiandrosterone in iron-induced epilepsy in rat brain
    • Mishra M., Singh R., Sharma D. Antiepileptic action of exogenous dehydroepiandrosterone in iron-induced epilepsy in rat brain. Epilepsy Behav. 2010, 19:264-271.
    • (2010) Epilepsy Behav. , vol.19 , pp. 264-271
    • Mishra, M.1    Singh, R.2    Sharma, D.3
  • 30
    • 0026733757 scopus 로고
    • Development of epileptic activity induced by iron injection into rat cerebral cortex: electrographic and behavioral characteristics
    • Moriwaki A., Hattori Y., Hayashi Y., Hori Y. Development of epileptic activity induced by iron injection into rat cerebral cortex: electrographic and behavioral characteristics. Electroencephalogr. Clin. Neurophysiol. 1992, 83:281-288.
    • (1992) Electroencephalogr. Clin. Neurophysiol. , vol.83 , pp. 281-288
    • Moriwaki, A.1    Hattori, Y.2    Hayashi, Y.3    Hori, Y.4
  • 31
    • 0032579754 scopus 로고    scopus 로고
    • Increased transcription of glutamate-aspartate transporter (GLAST/GluT-1) mRNA following kainic acid-induced limbic seizure
    • Nonaka M., Kohmura E., Yamashita T., Shimada S., Tanaka K., Yoshimine T., Tohyama M., Udea T.H. Increased transcription of glutamate-aspartate transporter (GLAST/GluT-1) mRNA following kainic acid-induced limbic seizure. Mol. Brain Res. 1998, 55:54-60.
    • (1998) Mol. Brain Res. , vol.55 , pp. 54-60
    • Nonaka, M.1    Kohmura, E.2    Yamashita, T.3    Shimada, S.4    Tanaka, K.5    Yoshimine, T.6    Tohyama, M.7    Udea, T.H.8
  • 34
    • 0035667276 scopus 로고    scopus 로고
    • Dehydroepiandrosterone and the relationship with aging and memory: a possible link with protein kinase C functional machinery
    • Racchi M., Govoni S., Solerte S.B., Galli C.L., Corsini E. Dehydroepiandrosterone and the relationship with aging and memory: a possible link with protein kinase C functional machinery. Brain Res. Rev. 2001, 37:287-293.
    • (2001) Brain Res. Rev. , vol.37 , pp. 287-293
    • Racchi, M.1    Govoni, S.2    Solerte, S.B.3    Galli, C.L.4    Corsini, E.5
  • 35
    • 38649112650 scopus 로고    scopus 로고
    • Focal reduction of neuronal glutamate transporters in human neocortical epilepsy
    • Rakhade S.N., Loeb J.A. Focal reduction of neuronal glutamate transporters in human neocortical epilepsy. Epilepsia 2008, 49:226-236.
    • (2008) Epilepsia , vol.49 , pp. 226-236
    • Rakhade, S.N.1    Loeb, J.A.2
  • 36
    • 0035147199 scopus 로고    scopus 로고
    • Extracellular amino acid levels measured with intracerebral microdialysis in the model of posttraumatic epilepsy induced by intracortical iron injection
    • Ronne-Engström E., Hillered L., Flink R., Kihlström L., Lindquist C., Nie J.X., Olsson Y., Silander H.C. Extracellular amino acid levels measured with intracerebral microdialysis in the model of posttraumatic epilepsy induced by intracortical iron injection. Epilepsy Res. 2001, 43:135-144.
    • (2001) Epilepsy Res. , vol.43 , pp. 135-144
    • Ronne-Engström, E.1    Hillered, L.2    Flink, R.3    Kihlström, L.4    Lindquist, C.5    Nie, J.X.6    Olsson, Y.7    Silander, H.C.8
  • 37
    • 0033198566 scopus 로고    scopus 로고
    • Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives
    • Rupprecht R., Holsboer F. Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives. Trends Neurosci. 1999, 22:410-416.
    • (1999) Trends Neurosci. , vol.22 , pp. 410-416
    • Rupprecht, R.1    Holsboer, F.2
  • 38
    • 0345258453 scopus 로고    scopus 로고
    • The effects of PBN (phenyl-butyl-nitrone) on GLT-1 levels and on the extracellular levels of amino acids and energy metabolites in a model of iron-induced post-traumatic epilepsy
    • Samuelsson C., Kumlien E., Elfving A., Lindholm D., Ronne-Engström E. The effects of PBN (phenyl-butyl-nitrone) on GLT-1 levels and on the extracellular levels of amino acids and energy metabolites in a model of iron-induced post-traumatic epilepsy. Epilepsy Res. 2003, 56:165-173.
    • (2003) Epilepsy Res. , vol.56 , pp. 165-173
    • Samuelsson, C.1    Kumlien, E.2    Elfving, A.3    Lindholm, D.4    Ronne-Engström, E.5
  • 39
    • 0034637129 scopus 로고    scopus 로고
    • Decreased cortical levels of astrocytic glutamate transport protein GLT-1 in a rat model of post-traumatic epilepsy
    • Samuelsson C., Kumlien E., Flink R., Lindholm D., Ronne-Engström E. Decreased cortical levels of astrocytic glutamate transport protein GLT-1 in a rat model of post-traumatic epilepsy. Neurosci. Lett. 2000, 289:185-188.
    • (2000) Neurosci. Lett. , vol.289 , pp. 185-188
    • Samuelsson, C.1    Kumlien, E.2    Flink, R.3    Lindholm, D.4    Ronne-Engström, E.5
  • 40
    • 51549101179 scopus 로고    scopus 로고
    • Exacerbated glial response in the aged mouse hippocampus following controlled cortical impact injury
    • Sandhir R., Julka D., Gill K.D. Exacerbated glial response in the aged mouse hippocampus following controlled cortical impact injury. Exp. Neurol. 2008, 213:372-380.
    • (2008) Exp. Neurol. , vol.213 , pp. 372-380
    • Sandhir, R.1    Julka, D.2    Gill, K.D.3
  • 41
    • 0027265521 scopus 로고
    • Age-related decline in multiple unit action potentials of CA3 region of rat hippocampus: correlation with lipid peroxidation and lipofuscin concentration and the effect of centrophenoxine
    • Sharma D., Maurya A.K., Singh R. Age-related decline in multiple unit action potentials of CA3 region of rat hippocampus: correlation with lipid peroxidation and lipofuscin concentration and the effect of centrophenoxine. Neurobiol. Aging 1993, 14:319-330.
    • (1993) Neurobiol. Aging , vol.14 , pp. 319-330
    • Sharma, D.1    Maurya, A.K.2    Singh, R.3
  • 42
    • 0032895021 scopus 로고    scopus 로고
    • Electroencephalographic study of iron-induced chronic focal cortical epilepsy in rat: propagation of cortical epileptic activity to substantia nigra and thalamus
    • Sharma V., Singh R. Electroencephalographic study of iron-induced chronic focal cortical epilepsy in rat: propagation of cortical epileptic activity to substantia nigra and thalamus. Indian J. Exp. Biol. 1999, 37:461-467.
    • (1999) Indian J. Exp. Biol. , vol.37 , pp. 461-467
    • Sharma, V.1    Singh, R.2
  • 43
    • 35548960463 scopus 로고    scopus 로고
    • Iron-induced experimental cortical seizures: electroencephalographic mapping of seizure spread in the subcortical brain areas
    • Sharma V., Prakash-Babu P., Singh A., Singh S., Singh R. Iron-induced experimental cortical seizures: electroencephalographic mapping of seizure spread in the subcortical brain areas. Seizure 2007, 16:680-690.
    • (2007) Seizure , vol.16 , pp. 680-690
    • Sharma, V.1    Prakash-Babu, P.2    Singh, A.3    Singh, S.4    Singh, R.5
  • 44
    • 34848842158 scopus 로고    scopus 로고
    • The role of glutamate transporters in neurodegenerative disease and potential opportunities for intervention
    • Sheldon A.L., Robinson M.B. The role of glutamate transporters in neurodegenerative disease and potential opportunities for intervention. Neurochem. Int. 2007, 51:333-355.
    • (2007) Neurochem. Int. , vol.51 , pp. 333-355
    • Sheldon, A.L.1    Robinson, M.B.2
  • 45
    • 0022507075 scopus 로고
    • Multiunitary activity analysis of cortical and subcorticle structures in paroxysmal discharges and grand mal seizure in photosensitive baboons
    • Silva-Barrat C., Menini C., Bryere P., Naquet R. Multiunitary activity analysis of cortical and subcorticle structures in paroxysmal discharges and grand mal seizure in photosensitive baboons. Electroencephalogr. Clin. Neurophysiol. 1987, 64:455-468.
    • (1987) Electroencephalogr. Clin. Neurophysiol. , vol.64 , pp. 455-468
    • Silva-Barrat, C.1    Menini, C.2    Bryere, P.3    Naquet, R.4
  • 46
    • 0025060193 scopus 로고
    • 3 induced epileptogenic foci in the rat brain
    • 3 induced epileptogenic foci in the rat brain. Epilepsia 1990, 31:15-26.
    • (1990) Epilepsia , vol.31 , pp. 15-26
    • Singh, R.1    Pathak, D.N.2
  • 47
    • 18844377220 scopus 로고    scopus 로고
    • Anti-lipidperoxidative role of exogenous dehydroepiandrosterone (DHEA) administration in normal ageing rat brain
    • Sinha N., Baquer N.Z., Sharma D. Anti-lipidperoxidative role of exogenous dehydroepiandrosterone (DHEA) administration in normal ageing rat brain. Indian J. Exp. Biol. 2005, 43:420-424.
    • (2005) Indian J. Exp. Biol. , vol.43 , pp. 420-424
    • Sinha, N.1    Baquer, N.Z.2    Sharma, D.3
  • 48
    • 67549140843 scopus 로고    scopus 로고
    • Na+, K+-ATPase activity in response to exogenous dehydroepiandrosterone administration in ageing rat brain
    • Taha A., Mishra M., Baquer N., Sharma Z.D. Na+, K+-ATPase activity in response to exogenous dehydroepiandrosterone administration in ageing rat brain. Indian J. Exp. Biol. 2008, 46:852-854.
    • (2008) Indian J. Exp. Biol. , vol.46 , pp. 852-854
    • Taha, A.1    Mishra, M.2    Baquer, N.3    Sharma, Z.D.4
  • 49
    • 0035138279 scopus 로고    scopus 로고
    • Effect of testosterone and clomiphene on spectral EEG and visual evoked response in a young man with post-traumatic epilepsy
    • Tan M., Tan U. Effect of testosterone and clomiphene on spectral EEG and visual evoked response in a young man with post-traumatic epilepsy. Int. J. Neurosci. 2001, 106:87-94.
    • (2001) Int. J. Neurosci. , vol.106 , pp. 87-94
    • Tan, M.1    Tan, U.2
  • 50
    • 0032145886 scopus 로고    scopus 로고
    • Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?
    • Trotti D., Danbolt N.C., Volterra A. Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?. Trends Pharmacol. Sci. 1998, 19:328-334.
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 328-334
    • Trotti, D.1    Danbolt, N.C.2    Volterra, A.3
  • 52
    • 0015524831 scopus 로고
    • Amino acid content of epileptogenic human brain: focal versus surrounding regions
    • Van Gelder N.M., Sherwin A.L., Rasmussen T. Amino acid content of epileptogenic human brain: focal versus surrounding regions. Brain Res. 1972, 40:385-393.
    • (1972) Brain Res. , vol.40 , pp. 385-393
    • Van Gelder, N.M.1    Sherwin, A.L.2    Rasmussen, T.3
  • 53
    • 0035798383 scopus 로고    scopus 로고
    • Treatment with dehydroepiandrosterone sulfate increases NMDA receptors in hippocampus and cortex
    • Wen S., Dong K., Onolfo J.P., Vincens M. Treatment with dehydroepiandrosterone sulfate increases NMDA receptors in hippocampus and cortex. Eur. J. Pharmacol. 2001, 430:373-374.
    • (2001) Eur. J. Pharmacol. , vol.430 , pp. 373-374
    • Wen, S.1    Dong, K.2    Onolfo, J.P.3    Vincens, M.4
  • 54
    • 0018167668 scopus 로고
    • Recurrent seizures induced by cortical iron injection: a model of post traumatic epilepsy
    • Willmore L.J., Sypert G.W., Munson J.B. Recurrent seizures induced by cortical iron injection: a model of post traumatic epilepsy. Ann. Neurol. 1978, 4:329-336.
    • (1978) Ann. Neurol. , vol.4 , pp. 329-336
    • Willmore, L.J.1    Sypert, G.W.2    Munson, J.B.3
  • 55
    • 0026231035 scopus 로고
    • Decreased glutamate release correlates with elevated dynorphin content in the hippocampus of aged rats with spatial learning deficits
    • Zhang W.Q., Mundy R.W., Thai L., Hudson P.M., Gallagher M., Tilson H.A., Hong J.S. Decreased glutamate release correlates with elevated dynorphin content in the hippocampus of aged rats with spatial learning deficits. Hippocampus 1991, 1:391-397.
    • (1991) Hippocampus , vol.1 , pp. 391-397
    • Zhang, W.Q.1    Mundy, R.W.2    Thai, L.3    Hudson, P.M.4    Gallagher, M.5    Tilson, H.A.6    Hong, J.S.7


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