Sequential changes in glutamate transporter mRNA levels during Fe3+-induced epileptogenesis

Molecular Brain Research

Volumn 75, Issue 1, 2000, Pages 105-112

  Doi, Taku ^a   Ueda, Yuto ^a   Tokumaru, Jun ^a   Mitsuyama, Yoshio ^a   Willmore, L James ^b  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Epilepsy; Ferric chloride; GLAST; Glutamate; Hippocampus; Transporter

Indexed keywords

4 AMINOBUTYRIC ACID; FERRIC CHLORIDE; GLUTAMATE TRANSPORTER; MESSENGER RNA;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; EPILEPSY; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; SEIZURE; SYNAPTIC TRANSMISSION;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CARRIER PROTEINS; CEREBRAL CORTEX; EPILEPSY; EXCITATORY AMINO ACID TRANSPORTER 1; FERRIC COMPOUNDS; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; HIPPOCAMPUS; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SYMPORTERS; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 0033958131     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00303-4     Document Type: Article

References (41)

1. Akbar M.T., Torp R., Danbolt N.C., Levy L.M., Meldrum B.S., Ottersen O.P. Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats. Neuroscience. 78:1997;351-359.
2. Arriza J.L., Eliasof S., Kavanaugh M.P., Amara S.G. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc. Natl. Acad. Sci. U. S. A. 94:1997;4155-4160.
3. Babb T.L., Pretorius J.K., Kupfer W.R., Crandall P.H. Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. J. Neurosci. 9:1989;2562-2574.
4. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
5. Croucher M.J., Bradform H.F. Kindling of full limbic seizures by repeated microinjection of excitatory amino acids into the rat amygdala. Brain Res. 501:1989;58-65.
6. +] coupled L-glutamate transporter purified from rat brain is localized in glial cell processes. Neuroscience. 51:1992;295-310.
7. Danbolt N.C. The high affinity uptake system for excitatory amino acid in the brain. Prog. Neurobiol. 44:1994;377-396.
8. M.J. During, In vivo neurochemistry of the conscious human brain: intrahippocampal microdialysis in epilepsy, in: T.E. Robinson, J.B. Justice, Jr. (Eds.), Microdialysis in the Neurosciences, Elsevier, Amsterdam, 1991, pp. 425-442.
9. During M.J., Spencer D.D. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet. 341:1993;1607-1610.
10. Eccles C.U., Dykes-Hoberg M., Rothstein J.D. Inhibition of synthesis of EAAC-1 glutamate transporter alters gamma-aminobutyric acid levels in discrete brain regions. Soc. Neurosci. (Abst.). 22:1996;1570.
11. Fairman W.A., Vandenberg R.J., Arriza J.L., Kavanaugh M.P., Amara S.G. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature. 375:1995;599-603.
12. Kanai Y., Smith C.P., Hediger M.A. The elusive transporters with a high affinity for glutamate. Trends Neurosci. 16:1993;365-370.
13. Kanai Y. Family of neural and acidic amino acid transporters: molecular biology, physiology and medical implications. Curr. Opin. Cell Biol. 9:1997;565-572.
14. Kanai Y., Hediger M.A. Primary structure and functional characterization of a high-affinity glutamate transporter. Nature. 360:1992;467-471.
15. Kapur J., Lothman E.W. NMDA receptor activation mediates the loss of GABAergic inhibition induced by recurrent seizures. Epilepsy Res. 5:1990;103-111.
16. Lallement G., Carpentier P., Collet A., Pernot-Marino I., Baubichon D., Blanchet G. Effects of soman-induced seizures on different extracellular amino acid levels and on glutamate uptake in rat hippocampus. Brain Res. 563:1991;234-240.
17. Lehre K.P., Levy L.M., Ottersen O.P., Storm-Mathisen J., Danbolt N.C. Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemcial observations. J. Neurosci. 15:1995;1835-1853.
18. Lothman E.W., Bennett J.P., Perlin J.B. Alterations in neurotransmitter amino acids in hippocampal kindled seizures. Epilepsy Res. 1:1987;313-320.
19. Masukawa L.M., Higashima M., Kim J.H., Spencer D.D. Epileptiform discharges evoked in hippocampal brain slices from epileptic patients. Brain Res. 493:1989;168-174.
20. Miller H.P., Levey A.I., Rothstein J.D., Tzingounis A.V., Conn P.J. Alterations in glutamate transporter protein levels in kindling-induced epilepsy. J. Neurochem. 68:1997;1564-1570.
21. Minamoto Y., Itano T., Tokuda M., Matsui H., Janjua N.A., Hosokawa K., Okada Y., Murakami T.H., Negi T., Hatase O. In vivo microdialysis of amino acid neurotransmitters in the hippocampus in amygdaloid kindled rat. Brain Res. 573:1992;345-348.
22. Morimoto K. Seizure-triggering mechanisms in the kindling model of epilepsy: collapse of GABA-mediated inhibition and activation of NMDA receptors. Neurosci. Biobehav. Rev. 13:1989;253-260.
23. Moriwaki A., Hattori Y., Nishida N., Hori Y. Electrocorticographic characterization of chronic iron-induced epilepsy in rats. Neurosci. Lett. 110:1990;72-76.
24. Nicholls D., Attwell D. The release and uptake of excitatory amino acids. Trends Pharmacol. Sci. 11:1990;462-468.
25. Nudel U., Zakut R., Shani M., Neuman S., Levy Z., Yaffe D. The nucleotide sequence of the rat cytoplasmic beta-actin gene. Nucleic Acids Res. 11:1983;1759-1771.
26. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, Orlando, 1986.
27. Pines G., Danbolt N.C., Bjørås M., Zhang Y., Bendahan A., Eide L., Koepsell H., Storm-Mathisen J., Seeberg E., Kanner B.I. Cloning and expression of a rat brain L-glutamate transporter. Nature. 360:1992;464-467.
28. Racine R.J. Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32:1972;281-294.
29. Rothstein J.D., Martin L., Levey A.I., Dykes-Hoberg M., Jin L., Wu D., Nash N., Kuncl R.W. Localization of neuronal and glial glutamate transporters. Neuron. 13:1994;713-725.
30. Rothstein J.D., Dykes-Hoberg M., Pardo C.A., Bristol L.A., Jin L., Kuncl R.W., Kanai Y., Hediger M.A., Wang Y., Schielke J.P., Welty D.F. Knockout of glutamate transporters reveals a major role for astroglial transport in excitatoxicity and clearance of glutamate. Neuron. 16:1996;675-686.
31. Rowley H.L., Martin K.F., Marsden C.A. Decreased GABA release following tonic-clinic seizures is associated with an increase in extracellular glutamate in rat hippocampus in vivo. Neuroscience. 68:1995;415-422.
32. Sato K., Morimoto K., Okamoto M. Anticonvulsant action of a non-competitive antagonist of NMDA receptors (MK-801) in the kindling model of epilepsy. Brain Res. 463:1988;12-20.
33. Seal R.P., Amara S.G. Excitatory amino acid transporter: a family in flux. Annu. Rev. Pharmacol. Toxicol. 39:1999;431-456.
34. Storck T., Schulte S., Hofmann K., Stoffel W. Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. U. S. A. 89:1992;10955-10959.
35. Takazawa A., Murashima Y.L., Minatogawa Y., Kojima T., Tanaka K., Yamauchi T. In vivo microdialysis monitoring for extracellular glutamate and GABA in the ventral hippocampus of the awake rat during kainate-induced seizures. Psychiatry Clin. Neurosci. 49:1995;275-277.
36. 3 causes spontaneous recurrent seizures. Exp. Neurol. 153:1998;123-127.
37. Ueda Y., Tsuru N. Bilateral seizure-related changes of extracellular glutamate concentration in hippocampi during development of amygdaloid kindling. Epilepsy Res. 18:1994;85-88.
38. Wade J.V., Samson F.E., Nelson S.R., Pazdernik T.L. Changes in extracellular amino acids during soman- and kainic acid-induced seizures. J. Neurochem. 49:1987;645-650.
39. Willmore L.J., Sypert G.W., Munson J.B. Recurrent seizures induced by cortical iron injection: a model of post-traumatic epilepsy. Ann. Neurol. 4:1978;329-336.
40. Willmore L.J., Sypert G.W., Munson J.B., Hurd R.W. Chronic focal epileptiform discharges induced by injection of iron into rat and cat cortex. Science. 200:1978;1501-1503.
41. Zhang W.Q., Hudson P.M., Sobotka T.J., Hong J.S., Tilson H.A. Extracellular concentrations of amino acid transmitters in ventral hippocampus during and after the development of kindling. Brain Res. 540:1991;315-318.