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Volumn 142, Issue 2, 2013, Pages 113-126

The G-protein-gated K+ channel, iKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation

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EID: 84883263180     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.201310996     Document Type: Article
Times cited : (66)

References (45)
  • 2
    • 33845764296 scopus 로고    scopus 로고
    • A guided tour into subcellular colocalization analysis in light microscopy
    • Bolte, S., and F.P. Cordelières. 2006. A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224:213- 232. http://dx.doi.org/10.1111/j.1365-2818.2006.01706.x
    • (2006) J. Microsc. , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelières, F.P.2
  • 3
    • 0023571525 scopus 로고
    • The fade of the response to acetylcholine at the rabbit isolated sino-atrial node
    • Boyett, M.R., and A. Roberts. 1987. The fade of the response to acetylcholine at the rabbit isolated sino-atrial node. J. Physiol. 393: 171-194.
    • (1987) J. Physiol. , vol.393 , pp. 171-194
    • Boyett, M.R.1    Roberts, A.2
  • 4
    • 0033847605 scopus 로고    scopus 로고
    • The sinoatrial node, a heterogeneous pacemaker structure
    • Boyett, M.R., H. Honjo, and I. Kodama. 2000. The sinoatrial node, a heterogeneous pacemaker structure. Cardiovasc. Res. 47:658-687. http://dx.doi.org/10.1016/S0008-6363(00)00135-8
    • (2000) Cardiovasc. Res. , vol.47 , pp. 658-687
    • Boyett, M.R.1    Honjo, H.2    Kodama, I.3
  • 5
    • 33646694997 scopus 로고    scopus 로고
    • Kir3- based inward rectifier potassium current: potential role in atrial tachycardia remodeling effects on atrial repolarization and arrhythmias
    • Cha, T.J., J.R. Ehrlich, D. Chartier, X.Y. Qi, L. Xiao, and S. Nattel. 2006. Kir3-based inward rectifier potassium current: potential role in atrial tachycardia remodeling effects on atrial repolarization and arrhythmias. Circulation. 113:1730-1737. http://dx.doiorg/10.1161/CIRCULATIONAHA.105.561738
    • (2006) Circulation , vol.113 , pp. 1730-1737
    • Cha, T.J.1    Ehrlich, J.R.2    Chartier, D.3    Qi, X.Y.4    Xiao, L.5    Nattel, S.6
  • 6
    • 76349123348 scopus 로고    scopus 로고
    • Development of the pacemaker tissues of the heart
    • Christoffels, V.M., G.J. Smits, A. Kispert, and A.F. Moorman. 2010. Development of the pacemaker tissues of the heart. Circ. Res. 106: 240-254. http://dx.doi.org/10.1161/CIRCRESAHA.109.205419
    • (2010) Circ. Res. , vol.106 , pp. 240-254
    • Christoffels, V.M.1    Smits, G.J.2    Kispert, A.3    Moorman, A.F.4
  • 7
    • 0027530224 scopus 로고
    • Pacemaker mechanisms in cardiac tissue
    • DiFrancesco, D. 1993. Pacemaker mechanisms in cardiac tissue. Annu. Rev. Physiol. 55:455-472. http://dx.doi.org/10.1146/annurevph.55.030193.002323
    • (1993) Annu. Rev. Physiol. , vol.55 , pp. 455-472
    • DiFrancesco, D.1
  • 8
    • 77649123846 scopus 로고    scopus 로고
    • The role of the funny current in pacemaker activity
    • DiFrancesco, D. 2010. The role of the funny current in pacemaker activity. Circ. Res. 106:434-446. http://dx.doi.org/10.1161/CIRCRESAHA.109.208041
    • (2010) Circ. Res. , vol.106 , pp. 434-446
    • DiFrancesco, D.1
  • 9
    • 0024598929 scopus 로고
    • Muscarinic modulation of cardiac rate at low acetylcholine concentrations
    • DiFrancesco, D., P. Ducouret, and R.B. Robinson. 1989. Muscarinic modulation of cardiac rate at low acetylcholine concentrations. Science. 243:669-671. http://dx.doi.org/10.1126/science.2916119
    • (1989) Science , vol.243 , pp. 669-671
    • DiFrancesco, D.1    Ducouret, P.2    Robinson, R.B.3
  • 11
    • 0033780037 scopus 로고    scopus 로고
    • The bee venom peptide tertiapin underlines the role of IKACh in acetylcholine-induced atrioventricular blocks
    • Drici, M.D., S. Diochot, C. Terrenoire, G. Romey, and M. Lazdunski. 2000. The bee venom peptide tertiapin underlines the role of IKACh in acetylcholine-induced atrioventricular blocks. Br. J. Pharmacol. 131:569-577. http://dx.doi.org/10.1038/sj.bjp.0703611
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 569-577
    • Drici, M.D.1    Diochot, S.2    Terrenoire, C.3    Romey, G.4    Lazdunski, M.5
  • 12
    • 0017144819 scopus 로고
    • Changes in membrane currents in bullfrog atrium produced by acetylcholine
    • Giles, W., and S.J. Noble. 1976. Changes in membrane currents in bullfrog atrium produced by acetylcholine. J. Physiol. 261:103-123.
    • (1976) J. Physiol. , vol.261 , pp. 103-123
    • Giles, W.1    Noble, S.J.2
  • 13
    • 39449098523 scopus 로고    scopus 로고
    • Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP
    • Harzheim, D., K.H. Pfeiffer, L. Fabritz, E. Kremmer, T. Buch, A. Waisman, P. Kirchhof, U.B. Kaupp, and R. Seifert. 2008. Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP. EMBO J. 27:692- 703. http://dx.doi.org/10.1038/emboj.2008.3
    • (2008) EMBO J , vol.27 , pp. 692-703
    • Harzheim, D.1    Pfeiffer, K.H.2    Fabritz, L.3    Kremmer, E.4    Buch, T.5    Waisman, A.6    Kirchhof, P.7    Kaupp, U.B.8    Seifert, R.9
  • 14
    • 35648939866 scopus 로고    scopus 로고
    • HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice
    • Herrmann, S., J. Stieber, G. Stöckl, F. Hofmann, and A. Ludwig. 2007. HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice. EMBO J. 26:4423-4432. http://dx.doi.org/10.1038/sj.emboj.7601868
    • (2007) EMBO J , vol.26 , pp. 4423-4432
    • Herrmann, S.1    Stieber, J.2    Stöckl, G.3    Hofmann, F.4    Ludwig, A.5
  • 15
    • 80055116113 scopus 로고    scopus 로고
    • Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart
    • Herrmann, S., B. Layh, and A. Ludwig. 2011. Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart. J. Mol. Cell. Cardiol. 51:997-1006. http://dx.doiorg/10.1016/j.yjmcc.2011.09.005
    • (2011) J. Mol. Cell. Cardiol. , vol.51 , pp. 997-1006
    • Herrmann, S.1    Layh, B.2    Ludwig, A.3
  • 18
    • 0033593226 scopus 로고    scopus 로고
    • GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels
    • Kennedy, M.E., J. Nemec, S. Corey, K. Wickman, and D.E. Clapham. 1999. GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels. J. Biol. Chem. 274:2571-2582. http://dx.doi.org/10.1074/jbc.274.4.2571
    • (1999) J. Biol. Chem. , vol.274 , pp. 2571-2582
    • Kennedy, M.E.1    Nemec, J.2    Corey, S.3    Wickman, K.4    Clapham, D.E.5
  • 20
    • 0035876203 scopus 로고    scopus 로고
    • Evaluation of the role of IKACh in atrial fibrillation using a mouse knockout model
    • Kovoor, P., K. Wickman, C.T. Maguire, W. Pu, J. Gehrmann, C.I. Berul, and D.E. Clapham. 2001. Evaluation of the role of IKACh in atrial fibrillation using a mouse knockout model. J. Am. Coll. Cardiol. 37:2136-2143. http://dx.doi.org/10.1016/S0735-1097(01)01304-3
    • (2001) J. Am. Coll. Cardiol. , vol.37 , pp. 2136-2143
    • Kovoor, P.1    Wickman, K.2    Maguire, C.T.3    Pu, W.4    Gehrmann, J.5    Berul, C.I.6    Clapham, D.E.7
  • 22
    • 77949379471 scopus 로고    scopus 로고
    • A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker
    • Lakatta, E.G., V.A. Maltsev, and T.M. Vinogradova. 2010. A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker. Circ. Res. 106:659-673. http://dx.doi.org/10.1161/CIRCRESAHA.109.206078
    • (2010) Circ. Res. , vol.106 , pp. 659-673
    • Lakatta, E.G.1    Maltsev, V.A.2    Vinogradova, T.M.3
  • 23
    • 0021824577 scopus 로고
    • The parasympathetic neuroeffector junction of the heart
    • Löffelholz, K., and A.J. Pappano. 1985. The parasympathetic neuroeffector junction of the heart. Pharmacol. Rev. 37:1-24.
    • (1985) Pharmacol. Rev. , vol.37 , pp. 1-24
    • Löffelholz, K.1    Pappano, A.J.2
  • 26
    • 0034853621 scopus 로고    scopus 로고
    • Properties of the hyperpolarization-activated current (If) in isolated mouse sino-atrial cells
    • Mangoni, M.E., and J. Nargeot. 2001. Properties of the hyperpolarization-activated current (If) in isolated mouse sino-atrial cells. Cardiovasc. Res. 52:51-64. http://dx.doi.org/10.1016/S0008-6363(01)00370-4
    • (2001) Cardiovasc. Res. , vol.52 , pp. 51-64
    • Mangoni, M.E.1    Nargeot, J.2
  • 27
    • 50349096521 scopus 로고    scopus 로고
    • Genesis and regulation of the heart automaticity
    • Mangoni, M.E., and J. Nargeot. 2008. Genesis and regulation of the heart automaticity. Physiol. Rev. 88:919-982. http://dx.doiorg/10.1152/physrev.00018.2007
    • (2008) Physiol. Rev. , vol.88 , pp. 919-982
    • Mangoni, M.E.1    Nargeot, J.2
  • 29
    • 13444304421 scopus 로고    scopus 로고
    • Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart
    • Marionneau, C., B. Couette, J. Liu, H. Li, M.E. Mangoni, J. Nargeot, M. Lei, D. Escande, and S. Demolombe. 2005. Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart. J. Physiol. 562:223-234. http://dx.doiorg/10.1113/jphysiol.2004.074047
    • (2005) J. Physiol. , vol.562 , pp. 223-234
    • Marionneau, C.1    Couette, B.2    Liu, J.3    Li, H.4    Mangoni, M.E.5    Nargeot, J.6    Lei, M.7    Escande, D.8    Demolombe, S.9
  • 30
    • 0027132966 scopus 로고
    • A direct negative inotropic effect of acetylcholine on rat ventricular myocytes
    • McMorn, S.O., S.M. Harrison, W.J. Zang, X.J. Yu, and M.R. Boyett. 1993. A direct negative inotropic effect of acetylcholine on rat ventricular myocytes. Am. J. Physiol. 265:H1393-H1400.
    • (1993) Am. J. Physiol. , vol.265
    • McMorn, S.O.1    Harrison, S.M.2    Zang, W.J.3    Yu, X.J.4    Boyett, M.R.5
  • 31
    • 34548426108 scopus 로고    scopus 로고
    • Muscarinic potassium channels augment dynamic and static heart rate responses to vagal stimulation
    • Mizuno, M., A. Kamiya, T. Kawada, T. Miyamoto, S. Shimizu, and M. Sugimachi. 2007. Muscarinic potassium channels augment dynamic and static heart rate responses to vagal stimulation. Am. J. Physiol. Heart Circ. Physiol. 293:H1564-H1570. http://dx.doiorg/10.1152/ajpheart.00368.2007
    • (2007) Am. J. Physiol. Heart Circ. Physiol. , vol.293
    • Mizuno, M.1    Kamiya, A.2    Kawada, T.3    Miyamoto, T.4    Shimizu, S.5    Sugimachi, M.6
  • 32
    • 0018075372 scopus 로고
    • Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell
    • Noma, A., and W. Trautwein. 1978. Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell. Pflugers Arch. 377:193-200. http://dx.doi.org/10.1007/BF00584272
    • (1978) Pflugers Arch , vol.377 , pp. 193-200
    • Noma, A.1    Trautwein, W.2
  • 33
    • 0033168058 scopus 로고    scopus 로고
    • Anatomical study of the neural ganglionated plexus in the canine right atrium: implications for selective denervation and electrophysiology of the sinoatrial node in dog
    • Pauza, D.H., V. Skripka, N. Pauziene, and R. Stropus. 1999. Anatomical study of the neural ganglionated plexus in the canine right atrium: implications for selective denervation and electrophysiology of the sinoatrial node in dog. Anat. Rec. 255:271-294. http://dx.doi.org/10.1002/(SICI)1097-0185(19990701)255:3271::AID-AR43.0.CO;2-2
    • (1999) Anat. Rec. , vol.255 , pp. 271-294
    • Pauza, D.H.1    Skripka, V.2    Pauziene, N.3    Stropus, R.4
  • 34
    • 0033855546 scopus 로고    scopus 로고
    • Morphology, distribution, and variability of the epicardiac neural ganglionated subplexuses in the human heart
    • Pauza, D.H., V. Skripka, N. Pauziene, and R. Stropus. 2000. Morphology, distribution, and variability of the epicardiac neural ganglionated subplexuses in the human heart. Anat. Rec. 259:353-382. http://dx.doi.org/10.1002/1097-0185(20000801)259:4<353::AIDAR10>3.0.CO;2-R
    • (2000) Anat. Rec. , vol.259 , pp. 353-382
    • Pauza, D.H.1    Skripka, V.2    Pauziene, N.3    Stropus, R.4
  • 35
    • 0027394464 scopus 로고
    • Mechanism of muscarinic control of the high-threshold calcium current in rabbit sino-atrial node myocytes
    • Petit-Jacques, J., P. Bois, J. Bescond, and J. Lenfant. 1993. Mechanism of muscarinic control of the high-threshold calcium current in rabbit sino-atrial node myocytes. Pflugers Arch. 423:21-27. http://dx.doi.org/10.1007/BF00374956
    • (1993) Pflugers Arch , vol.423 , pp. 21-27
    • Petit-Jacques, J.1    Bois, P.2    Bescond, J.3    Lenfant, J.4
  • 37
    • 0034846097 scopus 로고    scopus 로고
    • Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution
    • Verheijck, E.E., M.J. van Kempen, M. Veereschild, J. Lurvink, H.J. Jongsma, and L.N. Bouman. 2001. Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution. Cardiovasc. Res. 52:40-50. http://dx.doi.org/10.1016/S0008-6363(01)00364-9
    • (2001) Cardiovasc. Res. , vol.52 , pp. 40-50
    • Verheijck, E.E.1    van Kempen, M.J.2    Veereschild, M.3    Lurvink, J.4    Jongsma, H.J.5    Bouman, L.N.6
  • 38
    • 0029040744 scopus 로고
    • G- protein regulation of ion channels
    • Wickman, K.D., and D.E. Clapham. 1995. G-protein regulation of ion channels. Curr. Opin. Neurobiol. 5:278-285. http://dx.doi.org/10.1016/0959-4388(95)80039-5
    • (1995) Curr. Opin. Neurobiol. , vol.5 , pp. 278-285
    • Wickman, K.D.1    Clapham, D.E.2
  • 39
    • 0031909974 scopus 로고    scopus 로고
    • Abnormal heart rate regulation in GIRK4 knockout mice
    • Wickman, K., J. Nemec, S.J. Gendler, and D.E. Clapham. 1998. Abnormal heart rate regulation in GIRK4 knockout mice. Neuron. 20:103-114. http://dx.doi.org/10.1016/S0896-6273(00)80438-9
    • (1998) Neuron , vol.20 , pp. 103-114
    • Wickman, K.1    Nemec, J.2    Gendler, S.J.3    Clapham, D.E.4
  • 40
    • 0032968704 scopus 로고    scopus 로고
    • Structure, G protein activation, and functional relevance of the cardiac G protein-gated K+ channel
    • Wickman, K., G. Krapivinsky, S. Corey, M. Kennedy, J. Nemec, I. Medina, and D.E. Clapham. 1999. Structure, G protein activation, and functional relevance of the cardiac G protein-gated K+ channel, IKACh. Ann. N. Y. Acad. Sci. 868:386-398. http://dx.doiorg/10.1111/j.1749-6632.1999.tb11300.x
    • (1999) IKACh. Ann. N. Y. Acad. Sci. , vol.868 , pp. 386-398
    • Wickman, K.1    Krapivinsky, G.2    Corey, S.3    Kennedy, M.4    Nemec, J.5    Medina, I.6    Clapham, D.E.7
  • 42
    • 0036151570 scopus 로고    scopus 로고
    • + channels in the negative chronotropic effect of a muscarinic agonist
    • + channels in the negative chronotropic effect of a muscarinic agonist. J. Pharmacol. Exp. Ther. 300:681-687. http://dx.doi.org/10.1124/jpet.300.2.681
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 681-687
    • Yamada, M.1
  • 43
    • 33749430647 scopus 로고    scopus 로고
    • Extended atrial conduction system characterised by the expression of the HCN4 channel and connexin45
    • Yamamoto, M., H. Dobrzynski, J. Tellez, R. Niwa, R. Billeter, H. Honjo, I. Kodama, and M.R. Boyett. 2006. Extended atrial conduction system characterised by the expression of the HCN4 channel and connexin45. Cardiovasc. Res. 72:271-281. http://dx.doi.org/10.1016/j.cardiores.2006.07.026
    • (2006) Cardiovasc. Res. , vol.72 , pp. 271-281
    • Yamamoto, M.1    Dobrzynski, H.2    Tellez, J.3    Niwa, R.4    Billeter, R.5    Honjo, H.6    Kodama, I.7    Boyett, M.R.8
  • 44
    • 0027324602 scopus 로고
    • On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea-pig atrial cells
    • Zang, W.J., X.J. Yu, H. Honjo, M.S. Kirby, and M.R. Boyett. 1993. On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea-pig atrial cells. J. Physiol. 464:649-679.
    • (1993) J. Physiol. , vol.464 , pp. 649-679
    • Zang, W.J.1    Yu, X.J.2    Honjo, H.3    Kirby, M.S.4    Boyett, M.R.5
  • 45
    • 0029944490 scopus 로고    scopus 로고
    • 2+ and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node
    • 2+ and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node. J. Physiol. 491:347-355.
    • (1996) J. Physiol , vol.491 , pp. 347-355
    • Zaza, A.1    Robinson, R.B.2    DiFrancesco, D.3


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