-
1
-
-
67749116532
-
Control of heart rate by cAMP sensitivity of HCN channels
-
Alig, J., L. Marger, P. Mesirca, H. Ehmke, M.E. Mangoni, and D. Isbrandt. 2009. Control of heart rate by cAMP sensitivity of HCN channels. Proc. Natl. Acad. Sci. USA. 106:12189-12194. http://dx.doi.org/10.1073/pnas.0810332106
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12189-12194
-
-
Alig, J.1
Marger, L.2
Mesirca, P.3
Ehmke, H.4
Mangoni, M.E.5
Isbrandt, D.6
-
2
-
-
33845764296
-
A guided tour into subcellular colocalization analysis in light microscopy
-
Bolte, S., and F.P. Cordelières. 2006. A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. 224:213- 232. http://dx.doi.org/10.1111/j.1365-2818.2006.01706.x
-
(2006)
J. Microsc.
, vol.224
, pp. 213-232
-
-
Bolte, S.1
Cordelières, F.P.2
-
3
-
-
0023571525
-
The fade of the response to acetylcholine at the rabbit isolated sino-atrial node
-
Boyett, M.R., and A. Roberts. 1987. The fade of the response to acetylcholine at the rabbit isolated sino-atrial node. J. Physiol. 393: 171-194.
-
(1987)
J. Physiol.
, vol.393
, pp. 171-194
-
-
Boyett, M.R.1
Roberts, A.2
-
4
-
-
0033847605
-
The sinoatrial node, a heterogeneous pacemaker structure
-
Boyett, M.R., H. Honjo, and I. Kodama. 2000. The sinoatrial node, a heterogeneous pacemaker structure. Cardiovasc. Res. 47:658-687. http://dx.doi.org/10.1016/S0008-6363(00)00135-8
-
(2000)
Cardiovasc. Res.
, vol.47
, pp. 658-687
-
-
Boyett, M.R.1
Honjo, H.2
Kodama, I.3
-
5
-
-
33646694997
-
Kir3- based inward rectifier potassium current: potential role in atrial tachycardia remodeling effects on atrial repolarization and arrhythmias
-
Cha, T.J., J.R. Ehrlich, D. Chartier, X.Y. Qi, L. Xiao, and S. Nattel. 2006. Kir3-based inward rectifier potassium current: potential role in atrial tachycardia remodeling effects on atrial repolarization and arrhythmias. Circulation. 113:1730-1737. http://dx.doiorg/10.1161/CIRCULATIONAHA.105.561738
-
(2006)
Circulation
, vol.113
, pp. 1730-1737
-
-
Cha, T.J.1
Ehrlich, J.R.2
Chartier, D.3
Qi, X.Y.4
Xiao, L.5
Nattel, S.6
-
6
-
-
76349123348
-
Development of the pacemaker tissues of the heart
-
Christoffels, V.M., G.J. Smits, A. Kispert, and A.F. Moorman. 2010. Development of the pacemaker tissues of the heart. Circ. Res. 106: 240-254. http://dx.doi.org/10.1161/CIRCRESAHA.109.205419
-
(2010)
Circ. Res.
, vol.106
, pp. 240-254
-
-
Christoffels, V.M.1
Smits, G.J.2
Kispert, A.3
Moorman, A.F.4
-
7
-
-
0027530224
-
Pacemaker mechanisms in cardiac tissue
-
DiFrancesco, D. 1993. Pacemaker mechanisms in cardiac tissue. Annu. Rev. Physiol. 55:455-472. http://dx.doi.org/10.1146/annurevph.55.030193.002323
-
(1993)
Annu. Rev. Physiol.
, vol.55
, pp. 455-472
-
-
DiFrancesco, D.1
-
8
-
-
77649123846
-
The role of the funny current in pacemaker activity
-
DiFrancesco, D. 2010. The role of the funny current in pacemaker activity. Circ. Res. 106:434-446. http://dx.doi.org/10.1161/CIRCRESAHA.109.208041
-
(2010)
Circ. Res.
, vol.106
, pp. 434-446
-
-
DiFrancesco, D.1
-
9
-
-
0024598929
-
Muscarinic modulation of cardiac rate at low acetylcholine concentrations
-
DiFrancesco, D., P. Ducouret, and R.B. Robinson. 1989. Muscarinic modulation of cardiac rate at low acetylcholine concentrations. Science. 243:669-671. http://dx.doi.org/10.1126/science.2916119
-
(1989)
Science
, vol.243
, pp. 669-671
-
-
DiFrancesco, D.1
Ducouret, P.2
Robinson, R.B.3
-
10
-
-
0034832849
-
Distribution of the muscarinic K+ channel proteins Kir3.1 and Kir3.4 in the ventricle, atrium, and sinoatrial node of heart
-
Dobrzynski, H., D.D. Marples, H. Musa, T.T. Yamanushi, Z. Henderson, Y. Takagishi, H. Honjo, I. Kodama, and M.R. Boyett. 2001. Distribution of the muscarinic K+ channel proteins Kir3.1 and Kir3.4 in the ventricle, atrium, and sinoatrial node of heart. J. Histochem. Cytochem. 49:1221-1234. http://dx.doi.org/10.1177/002215540104901004
-
(2001)
J. Histochem. Cytochem.
, vol.49
, pp. 1221-1234
-
-
Dobrzynski, H.1
Marples, D.D.2
Musa, H.3
Yamanushi, T.T.4
Henderson, Z.5
Takagishi, Y.6
Honjo, H.7
Kodama, I.8
Boyett, M.R.9
-
11
-
-
0033780037
-
The bee venom peptide tertiapin underlines the role of IKACh in acetylcholine-induced atrioventricular blocks
-
Drici, M.D., S. Diochot, C. Terrenoire, G. Romey, and M. Lazdunski. 2000. The bee venom peptide tertiapin underlines the role of IKACh in acetylcholine-induced atrioventricular blocks. Br. J. Pharmacol. 131:569-577. http://dx.doi.org/10.1038/sj.bjp.0703611
-
(2000)
Br. J. Pharmacol.
, vol.131
, pp. 569-577
-
-
Drici, M.D.1
Diochot, S.2
Terrenoire, C.3
Romey, G.4
Lazdunski, M.5
-
12
-
-
0017144819
-
Changes in membrane currents in bullfrog atrium produced by acetylcholine
-
Giles, W., and S.J. Noble. 1976. Changes in membrane currents in bullfrog atrium produced by acetylcholine. J. Physiol. 261:103-123.
-
(1976)
J. Physiol.
, vol.261
, pp. 103-123
-
-
Giles, W.1
Noble, S.J.2
-
13
-
-
39449098523
-
Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP
-
Harzheim, D., K.H. Pfeiffer, L. Fabritz, E. Kremmer, T. Buch, A. Waisman, P. Kirchhof, U.B. Kaupp, and R. Seifert. 2008. Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP. EMBO J. 27:692- 703. http://dx.doi.org/10.1038/emboj.2008.3
-
(2008)
EMBO J
, vol.27
, pp. 692-703
-
-
Harzheim, D.1
Pfeiffer, K.H.2
Fabritz, L.3
Kremmer, E.4
Buch, T.5
Waisman, A.6
Kirchhof, P.7
Kaupp, U.B.8
Seifert, R.9
-
14
-
-
35648939866
-
HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice
-
Herrmann, S., J. Stieber, G. Stöckl, F. Hofmann, and A. Ludwig. 2007. HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice. EMBO J. 26:4423-4432. http://dx.doi.org/10.1038/sj.emboj.7601868
-
(2007)
EMBO J
, vol.26
, pp. 4423-4432
-
-
Herrmann, S.1
Stieber, J.2
Stöckl, G.3
Hofmann, F.4
Ludwig, A.5
-
15
-
-
80055116113
-
Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart
-
Herrmann, S., B. Layh, and A. Ludwig. 2011. Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart. J. Mol. Cell. Cardiol. 51:997-1006. http://dx.doiorg/10.1016/j.yjmcc.2011.09.005
-
(2011)
J. Mol. Cell. Cardiol.
, vol.51
, pp. 997-1006
-
-
Herrmann, S.1
Layh, B.2
Ludwig, A.3
-
16
-
-
0035942276
-
Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels
-
Ino, M., T. Yoshinaga, M. Wakamori, N. Miyamoto, E. Takahashi, J. Sonoda, T. Kagaya, T. Oki, T. Nagasu, Y. Nishizawa, et al. 2001. Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels. Proc. Natl. Acad. Sci. USA. 98:5323-5328. http://dx.doi.org/101073/pnas.081089398
-
(2001)
Proc. Natl. Acad. Sci. USA.
, vol.98
, pp. 5323-5328
-
-
Ino, M.1
Yoshinaga, T.2
Wakamori, M.3
Miyamoto, N.4
Takahashi, E.5
Sonoda, J.6
Kagaya, T.7
Oki, T.8
Nagasu, T.9
Nishizawa, Y.10
-
18
-
-
0033593226
-
GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels
-
Kennedy, M.E., J. Nemec, S. Corey, K. Wickman, and D.E. Clapham. 1999. GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels. J. Biol. Chem. 274:2571-2582. http://dx.doi.org/10.1074/jbc.274.4.2571
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2571-2582
-
-
Kennedy, M.E.1
Nemec, J.2
Corey, S.3
Wickman, K.4
Clapham, D.E.5
-
19
-
-
0038000737
-
Altered sinus nodal and atrioventricular nodal function in freely moving mice overexpressing the A1 adenosine receptor
-
Kirchhof, P., L. Fabritz, L. Fortmuller, G.P. Matherne, A. Lankford, H.A. Baba, W. Schmitz, G. Breithardt, J. Neumann, and P. Boknik. 2003. Altered sinus nodal and atrioventricular nodal function in freely moving mice overexpressing the A1 adenosine receptor. Am. J. Physiol. Heart Circ. Physiol. 285:H145-H153.
-
(2003)
Am. J. Physiol. Heart Circ. Physiol.
, vol.285
-
-
Kirchhof, P.1
Fabritz, L.2
Fortmuller, L.3
Matherne, G.P.4
Lankford, A.5
Baba, H.A.6
Schmitz, W.7
Breithardt, G.8
Neumann, J.9
Boknik, P.10
-
20
-
-
0035876203
-
Evaluation of the role of IKACh in atrial fibrillation using a mouse knockout model
-
Kovoor, P., K. Wickman, C.T. Maguire, W. Pu, J. Gehrmann, C.I. Berul, and D.E. Clapham. 2001. Evaluation of the role of IKACh in atrial fibrillation using a mouse knockout model. J. Am. Coll. Cardiol. 37:2136-2143. http://dx.doi.org/10.1016/S0735-1097(01)01304-3
-
(2001)
J. Am. Coll. Cardiol.
, vol.37
, pp. 2136-2143
-
-
Kovoor, P.1
Wickman, K.2
Maguire, C.T.3
Pu, W.4
Gehrmann, J.5
Berul, C.I.6
Clapham, D.E.7
-
22
-
-
77949379471
-
A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker
-
Lakatta, E.G., V.A. Maltsev, and T.M. Vinogradova. 2010. A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker. Circ. Res. 106:659-673. http://dx.doi.org/10.1161/CIRCRESAHA.109.206078
-
(2010)
Circ. Res.
, vol.106
, pp. 659-673
-
-
Lakatta, E.G.1
Maltsev, V.A.2
Vinogradova, T.M.3
-
23
-
-
0021824577
-
The parasympathetic neuroeffector junction of the heart
-
Löffelholz, K., and A.J. Pappano. 1985. The parasympathetic neuroeffector junction of the heart. Pharmacol. Rev. 37:1-24.
-
(1985)
Pharmacol. Rev.
, vol.37
, pp. 1-24
-
-
Löffelholz, K.1
Pappano, A.J.2
-
25
-
-
69249150907
-
2+ cycling and IKACh
-
2+ cycling and IKACh. Am. J. Physiol. Heart Circ. Physiol. 297:H949-H959. http://dx.doi.org/10.1152/ajpheart.01340.2008
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.297
-
-
Lyashkov, A.E.1
Vinogradova, T.M.2
Zahanich, I.3
Li, Y.4
Younes, A.5
Nuss, H.B.6
Spurgeon, H.A.7
Maltsev, V.A.8
Lakatta, E.G.9
-
26
-
-
0034853621
-
Properties of the hyperpolarization-activated current (If) in isolated mouse sino-atrial cells
-
Mangoni, M.E., and J. Nargeot. 2001. Properties of the hyperpolarization-activated current (If) in isolated mouse sino-atrial cells. Cardiovasc. Res. 52:51-64. http://dx.doi.org/10.1016/S0008-6363(01)00370-4
-
(2001)
Cardiovasc. Res.
, vol.52
, pp. 51-64
-
-
Mangoni, M.E.1
Nargeot, J.2
-
27
-
-
50349096521
-
Genesis and regulation of the heart automaticity
-
Mangoni, M.E., and J. Nargeot. 2008. Genesis and regulation of the heart automaticity. Physiol. Rev. 88:919-982. http://dx.doiorg/10.1152/physrev.00018.2007
-
(2008)
Physiol. Rev.
, vol.88
, pp. 919-982
-
-
Mangoni, M.E.1
Nargeot, J.2
-
29
-
-
13444304421
-
Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart
-
Marionneau, C., B. Couette, J. Liu, H. Li, M.E. Mangoni, J. Nargeot, M. Lei, D. Escande, and S. Demolombe. 2005. Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart. J. Physiol. 562:223-234. http://dx.doiorg/10.1113/jphysiol.2004.074047
-
(2005)
J. Physiol.
, vol.562
, pp. 223-234
-
-
Marionneau, C.1
Couette, B.2
Liu, J.3
Li, H.4
Mangoni, M.E.5
Nargeot, J.6
Lei, M.7
Escande, D.8
Demolombe, S.9
-
30
-
-
0027132966
-
A direct negative inotropic effect of acetylcholine on rat ventricular myocytes
-
McMorn, S.O., S.M. Harrison, W.J. Zang, X.J. Yu, and M.R. Boyett. 1993. A direct negative inotropic effect of acetylcholine on rat ventricular myocytes. Am. J. Physiol. 265:H1393-H1400.
-
(1993)
Am. J. Physiol.
, vol.265
-
-
McMorn, S.O.1
Harrison, S.M.2
Zang, W.J.3
Yu, X.J.4
Boyett, M.R.5
-
31
-
-
34548426108
-
Muscarinic potassium channels augment dynamic and static heart rate responses to vagal stimulation
-
Mizuno, M., A. Kamiya, T. Kawada, T. Miyamoto, S. Shimizu, and M. Sugimachi. 2007. Muscarinic potassium channels augment dynamic and static heart rate responses to vagal stimulation. Am. J. Physiol. Heart Circ. Physiol. 293:H1564-H1570. http://dx.doiorg/10.1152/ajpheart.00368.2007
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.293
-
-
Mizuno, M.1
Kamiya, A.2
Kawada, T.3
Miyamoto, T.4
Shimizu, S.5
Sugimachi, M.6
-
32
-
-
0018075372
-
Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell
-
Noma, A., and W. Trautwein. 1978. Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell. Pflugers Arch. 377:193-200. http://dx.doi.org/10.1007/BF00584272
-
(1978)
Pflugers Arch
, vol.377
, pp. 193-200
-
-
Noma, A.1
Trautwein, W.2
-
33
-
-
0033168058
-
Anatomical study of the neural ganglionated plexus in the canine right atrium: implications for selective denervation and electrophysiology of the sinoatrial node in dog
-
Pauza, D.H., V. Skripka, N. Pauziene, and R. Stropus. 1999. Anatomical study of the neural ganglionated plexus in the canine right atrium: implications for selective denervation and electrophysiology of the sinoatrial node in dog. Anat. Rec. 255:271-294. http://dx.doi.org/10.1002/(SICI)1097-0185(19990701)255:3271::AID-AR43.0.CO;2-2
-
(1999)
Anat. Rec.
, vol.255
, pp. 271-294
-
-
Pauza, D.H.1
Skripka, V.2
Pauziene, N.3
Stropus, R.4
-
34
-
-
0033855546
-
Morphology, distribution, and variability of the epicardiac neural ganglionated subplexuses in the human heart
-
Pauza, D.H., V. Skripka, N. Pauziene, and R. Stropus. 2000. Morphology, distribution, and variability of the epicardiac neural ganglionated subplexuses in the human heart. Anat. Rec. 259:353-382. http://dx.doi.org/10.1002/1097-0185(20000801)259:4<353::AIDAR10>3.0.CO;2-R
-
(2000)
Anat. Rec.
, vol.259
, pp. 353-382
-
-
Pauza, D.H.1
Skripka, V.2
Pauziene, N.3
Stropus, R.4
-
35
-
-
0027394464
-
Mechanism of muscarinic control of the high-threshold calcium current in rabbit sino-atrial node myocytes
-
Petit-Jacques, J., P. Bois, J. Bescond, and J. Lenfant. 1993. Mechanism of muscarinic control of the high-threshold calcium current in rabbit sino-atrial node myocytes. Pflugers Arch. 423:21-27. http://dx.doi.org/10.1007/BF00374956
-
(1993)
Pflugers Arch
, vol.423
, pp. 21-27
-
-
Petit-Jacques, J.1
Bois, P.2
Bescond, J.3
Lenfant, J.4
-
36
-
-
72449157040
-
2+ transient, cAMP production and pacemaker frequency of rabbit sinoatrial node cells
-
2+ transient, cAMP production and pacemaker frequency of rabbit sinoatrial node cells. Basic Res. Cardiol. 105:73-87. http://dx.doi.org/10.1007/s00395-009-0048-9
-
(2010)
Basic Res. Cardiol.
, vol.105
, pp. 73-87
-
-
van Borren, M.M.1
Verkerk, A.O.2
Wilders, R.3
Hajji, N.4
Zegers, J.G.5
Bourier, J.6
Tan, H.L.7
Verheijck, E.E.8
Peters, S.L.9
Alewijnse, A.E.10
Ravesloot, J.H.11
-
37
-
-
0034846097
-
Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution
-
Verheijck, E.E., M.J. van Kempen, M. Veereschild, J. Lurvink, H.J. Jongsma, and L.N. Bouman. 2001. Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution. Cardiovasc. Res. 52:40-50. http://dx.doi.org/10.1016/S0008-6363(01)00364-9
-
(2001)
Cardiovasc. Res.
, vol.52
, pp. 40-50
-
-
Verheijck, E.E.1
van Kempen, M.J.2
Veereschild, M.3
Lurvink, J.4
Jongsma, H.J.5
Bouman, L.N.6
-
38
-
-
0029040744
-
G- protein regulation of ion channels
-
Wickman, K.D., and D.E. Clapham. 1995. G-protein regulation of ion channels. Curr. Opin. Neurobiol. 5:278-285. http://dx.doi.org/10.1016/0959-4388(95)80039-5
-
(1995)
Curr. Opin. Neurobiol.
, vol.5
, pp. 278-285
-
-
Wickman, K.D.1
Clapham, D.E.2
-
39
-
-
0031909974
-
Abnormal heart rate regulation in GIRK4 knockout mice
-
Wickman, K., J. Nemec, S.J. Gendler, and D.E. Clapham. 1998. Abnormal heart rate regulation in GIRK4 knockout mice. Neuron. 20:103-114. http://dx.doi.org/10.1016/S0896-6273(00)80438-9
-
(1998)
Neuron
, vol.20
, pp. 103-114
-
-
Wickman, K.1
Nemec, J.2
Gendler, S.J.3
Clapham, D.E.4
-
40
-
-
0032968704
-
Structure, G protein activation, and functional relevance of the cardiac G protein-gated K+ channel
-
Wickman, K., G. Krapivinsky, S. Corey, M. Kennedy, J. Nemec, I. Medina, and D.E. Clapham. 1999. Structure, G protein activation, and functional relevance of the cardiac G protein-gated K+ channel, IKACh. Ann. N. Y. Acad. Sci. 868:386-398. http://dx.doiorg/10.1111/j.1749-6632.1999.tb11300.x
-
(1999)
IKACh. Ann. N. Y. Acad. Sci.
, vol.868
, pp. 386-398
-
-
Wickman, K.1
Krapivinsky, G.2
Corey, S.3
Kennedy, M.4
Nemec, J.5
Medina, I.6
Clapham, D.E.7
-
42
-
-
0036151570
-
+ channels in the negative chronotropic effect of a muscarinic agonist
-
+ channels in the negative chronotropic effect of a muscarinic agonist. J. Pharmacol. Exp. Ther. 300:681-687. http://dx.doi.org/10.1124/jpet.300.2.681
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 681-687
-
-
Yamada, M.1
-
43
-
-
33749430647
-
Extended atrial conduction system characterised by the expression of the HCN4 channel and connexin45
-
Yamamoto, M., H. Dobrzynski, J. Tellez, R. Niwa, R. Billeter, H. Honjo, I. Kodama, and M.R. Boyett. 2006. Extended atrial conduction system characterised by the expression of the HCN4 channel and connexin45. Cardiovasc. Res. 72:271-281. http://dx.doi.org/10.1016/j.cardiores.2006.07.026
-
(2006)
Cardiovasc. Res.
, vol.72
, pp. 271-281
-
-
Yamamoto, M.1
Dobrzynski, H.2
Tellez, J.3
Niwa, R.4
Billeter, R.5
Honjo, H.6
Kodama, I.7
Boyett, M.R.8
-
44
-
-
0027324602
-
On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea-pig atrial cells
-
Zang, W.J., X.J. Yu, H. Honjo, M.S. Kirby, and M.R. Boyett. 1993. On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea-pig atrial cells. J. Physiol. 464:649-679.
-
(1993)
J. Physiol.
, vol.464
, pp. 649-679
-
-
Zang, W.J.1
Yu, X.J.2
Honjo, H.3
Kirby, M.S.4
Boyett, M.R.5
-
45
-
-
0029944490
-
2+ and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node
-
2+ and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node. J. Physiol. 491:347-355.
-
(1996)
J. Physiol
, vol.491
, pp. 347-355
-
-
Zaza, A.1
Robinson, R.B.2
DiFrancesco, D.3
|