-
1
-
-
3042750282
-
The tissue kallikrein family of serine proteases: Functional roles in human disease and potential as clinical biomarkers
-
Clements JA, Willemsen NM, Myers SA, et al. The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers. Crit Rev Clin Lab Sci 2004; 41: 265-312.
-
(2004)
Crit Rev Clin Lab Sci
, vol.41
, pp. 265-312
-
-
Clements, J.A.1
Willemsen, N.M.2
Myers, S.A.3
-
2
-
-
23244459692
-
Human tissue kallikreins: From gene structure to function and clinical applications
-
Yousef GM, Obiezu CV, Luo LY, et al. Human tissue kallikreins: from gene structure to function and clinical applications. Adv Clin Chem 2005; 39: 11-79.
-
(2005)
Adv Clin Chem
, vol.39
, pp. 11-79
-
-
Yousef, G.M.1
Obiezu, C.V.2
Luo, L.Y.3
-
3
-
-
34447519008
-
Fifty years of research on the plasma kallikrein-kinin system: From protein structure and function to cell biology and in-vivo pathophysiology
-
Sainz IM, Pixley RA, Colman RW. Fifty years of research on the plasma kallikrein-kinin system: from protein structure and function to cell biology and in-vivo pathophysiology. Thromb Haemost 2007; 98: 77-83.
-
(2007)
Thromb Haemost
, vol.98
, pp. 77-83
-
-
Sainz, I.M.1
Pixley, R.A.2
Colman, R.W.3
-
4
-
-
0032416326
-
Bradykinin formation. Plasma and tissue pathways and cellular interactions
-
Kaplan AP, Joseph K, Shibayama Y, et al. Bradykinin formation. Plasma and tissue pathways and cellular interactions. Clin Rev Allergy Immunol 1998; 16: 403-429.
-
(1998)
Clin Rev Allergy Immunol
, vol.16
, pp. 403-429
-
-
Kaplan, A.P.1
Joseph, K.2
Shibayama, Y.3
-
6
-
-
0030830360
-
Contact system: A vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes
-
Colman RW, Schmaier AH. Contact system: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes. Blood 1997; 90: 3819-3843.
-
(1997)
Blood
, vol.90
, pp. 3819-3843
-
-
Colman, R.W.1
Schmaier, A.H.2
-
7
-
-
0035018273
-
The new human tissue kallikrein gene family: Structure, function, and association to disease
-
Yousef GM, Diamandis EP. The new human tissue kallikrein gene family: structure, function, and association to disease. Endocr Rev 2001; 22: 184-204.
-
(2001)
Endocr Rev
, vol.22
, pp. 184-204
-
-
Yousef, G.M.1
Diamandis, E.P.2
-
8
-
-
84977670009
-
Molecular Recognition Properties of Kallikreinrelated Peptidases on Synthetic and Endogenous Substrates
-
LeBeau AM, Craik, Charles S. Molecular Recognition Properties of Kallikreinrelated Peptidases on Synthetic and Endogenous Substrates. Kallikrein Rel Peptid 2012; 2012: 117-140.
-
(2012)
Kallikrein Rel Peptid
, vol.2012
, pp. 117-140
-
-
LeBeau, A.M.1
Craik2
Charles, S.3
-
10
-
-
81155133305
-
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding
-
Revenko AS, Gao D, Crosby JR, et al. Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding. Blood 2011; 118: 5302-5311.
-
(2011)
Blood
, vol.118
, pp. 5302-5311
-
-
Revenko, A.S.1
Gao, D.2
Crosby, J.R.3
-
11
-
-
33645066112
-
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis
-
Kleinschnitz C, Stoll G, Bendszus M, et al. Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis. J Exp Med 2006; 203: 513-518.
-
(2006)
J Exp Med
, vol.203
, pp. 513-518
-
-
Kleinschnitz, C.1
Stoll, G.2
Bendszus, M.3
-
12
-
-
38949099750
-
Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays thrombosis
-
Merkulov S, Zhang WM, Komar AA, et al. Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays thrombosis. Blood 2008; 111: 1274-1281.
-
(2008)
Blood
, vol.111
, pp. 1274-1281
-
-
Merkulov, S.1
Zhang, W.M.2
Komar, A.A.3
-
14
-
-
33845219794
-
Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III
-
Cichon S, Martin L, Hennies HC, et al. Increased activity of coagulation factor XII (Hageman factor) causes hereditary angioedema type III. Am J Hum Genet 2006; 79: 1098-1104.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 1098-1104
-
-
Cichon, S.1
Martin, L.2
Hennies, H.C.3
-
15
-
-
0035019596
-
Assembly and activation of HK-PK complex on endothelial cells results in bradykinin liberation and NO formation
-
Zhao Y, Qiu Q, Mahdi F, et al. Assembly and activation of HK-PK complex on endothelial cells results in bradykinin liberation and NO formation. Am J Physiol Heart Circ Physiol 2001; 280: H1821-1829.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Zhao, Y.1
Qiu, Q.2
Mahdi, F.3
-
16
-
-
0036661263
-
Human tissue kallikreins: A new enzymatic cascade pathway?
-
Yousef GM, Diamandis EP. Human tissue kallikreins: a new enzymatic cascade pathway? Biol Chem 2002; 383: 1045-1057.
-
(2002)
Biol Chem
, vol.383
, pp. 1045-1057
-
-
Yousef, G.M.1
Diamandis, E.P.2
-
17
-
-
41649087844
-
Substrate specificity of human kallikreins 1 and 6 determined by phage display
-
Li HX, Hwang BY, Laxmikanthan G, et al. Substrate specificity of human kallikreins 1 and 6 determined by phage display. Protein Sci 2008; 17: 664-672.
-
(2008)
Protein Sci
, vol.17
, pp. 664-672
-
-
Li, H.X.1
Hwang, B.Y.2
Laxmikanthan, G.3
-
18
-
-
36349032259
-
Molecular modeling of the prekallikrein structure provides insights into high-molecular-weight kininogen binding and zymogen activation
-
Hooley E, McEwan PA, Emsley J. Molecular modeling of the prekallikrein structure provides insights into high-molecular-weight kininogen binding and zymogen activation. J Thromb Haemost 2007; 5: 2461-2466.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 2461-2466
-
-
Hooley, E.1
McEwan, P.A.2
Emsley, J.3
-
19
-
-
13944276781
-
1.70 A X-ray structure of human apo kallikrein 1: Structural changes upon peptide inhibitor/substrate binding
-
Laxmikanthan G, Blaber SI, Bernett MJ, et al. 1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding. Proteins 2005; 58: 802-814.
-
(2005)
Proteins
, vol.58
, pp. 802-814
-
-
Laxmikanthan, G.1
Blaber, S.I.2
Bernett, M.J.3
-
20
-
-
0018369074
-
Substrate specificity of porcine pancreatic kallikrein
-
Fiedler F, Leysath G. Substrate specificity of porcine pancreatic kallikrein. Adv Exp Med Biol 1979; 120A: 261-271.
-
(1979)
Adv Exp Med Biol
, vol.120 A
, pp. 261-271
-
-
Fiedler, F.1
Leysath, G.2
-
21
-
-
0030693961
-
Hydrolysis of somatostatin by human tissue kallikrein after the amino acid pair phe-Phe
-
Pimenta DC, Juliano MA, Juliano L. Hydrolysis of somatostatin by human tissue kallikrein after the amino acid pair phe-Phe. Biochem J 1997; 327: 27-30.
-
(1997)
Biochem J
, vol.327
, pp. 27-30
-
-
Pimenta, D.C.1
Juliano, M.A.2
Juliano, L.3
-
22
-
-
0033814795
-
Enzymatic action of prostate-specific antigen (PSA or hK3): Substrate specificity and regulation by Zn(2+), a tight-binding inhibitor
-
Malm J, Hellman J, Hogg P, et al. Enzymatic action of prostate-specific antigen (PSA or hK3): substrate specificity and regulation by Zn(2+), a tight-binding inhibitor. Prostate 2000; 45: 132-139.
-
(2000)
Prostate
, vol.45
, pp. 132-139
-
-
Malm, J.1
Hellman, J.2
Hogg, P.3
-
23
-
-
0028685490
-
Fitting a mixture model by expectation maximization to discover motifs in biopolymers
-
Bailey TL, Elkan C. Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol 1994; 2: 28-36.
-
(1994)
Proc Int Conf Intell Syst Mol Biol
, vol.2
, pp. 28-36
-
-
Bailey, T.L.1
Elkan, C.2
-
24
-
-
57649128315
-
S(1) and S(2) subsite specificities of human plasma kallikrein and tissue kallikrein 1 for the hydrolysis of peptides derived from the bradykinin domain of human kininogen
-
Lima AR, Alves FM, Angelo PF, et al. S(1) and S(2) subsite specificities of human plasma kallikrein and tissue kallikrein 1 for the hydrolysis of peptides derived from the bradykinin domain of human kininogen. Biol Chem 2008; 389: 1487-1494.
-
(2008)
Biol Chem
, vol.389
, pp. 1487-1494
-
-
Lima, A.R.1
Alves, F.M.2
Angelo, P.F.3
-
25
-
-
0028897092
-
Determinants of the unusual cleavage specificity of lysyl-bradykinin-releasing kallikreins
-
Chagas JR, Portaro FC, Hirata IY, et al. Determinants of the unusual cleavage specificity of lysyl-bradykinin-releasing kallikreins. Biochem J 1995; 306: 63-69.
-
(1995)
Biochem J
, vol.306
, pp. 63-69
-
-
Chagas, J.R.1
Portaro, F.C.2
Hirata, I.Y.3
-
26
-
-
78149358426
-
Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)
-
Goettig P, Magdolen V, Brandstetter H. Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs). Biochimie 2010; 92: 1546-1567.
-
(2010)
Biochimie
, vol.92
, pp. 1546-1567
-
-
Goettig, P.1
Magdolen, V.2
Brandstetter, H.3
-
27
-
-
0020645978
-
Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement, structure and comparison with its components and with the bovine trypsin-pancreatic trypsin inhibitor complex
-
Chen Z, Bode W. Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement, structure and comparison with its components and with the bovine trypsin-pancreatic trypsin inhibitor complex. J Mol Biol 1983; 164: 283-311.
-
(1983)
J Mol Biol
, vol.164
, pp. 283-311
-
-
Chen, Z.1
Bode, W.2
-
28
-
-
0031568813
-
A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex
-
Mittl PR, Di Marco S, Fendrich G, et al. A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex. Structure 1997; 5: 253-264.
-
(1997)
Structure
, vol.5
, pp. 253-264
-
-
Mittl, P.R.1
Di Marco, S.2
Fendrich, G.3
-
29
-
-
0034624099
-
Roles of the P1, P2, and P3 residues in determining inhibitory specificity of kallistatin toward human tissue kallikrein
-
Chen VC, Chao L, Chao J. Roles of the P1, P2, and P3 residues in determining inhibitory specificity of kallistatin toward human tissue kallikrein. J Biol Chem 2000; 275: 38457-38466.
-
(2000)
J Biol Chem
, vol.275
, pp. 38457-38466
-
-
Chen, V.C.1
Chao, L.2
Chao, J.3
-
31
-
-
0031956497
-
Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes
-
Khan AR, James MN. Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes. Protein Sci 1998; 7: 815-836.
-
(1998)
Protein Sci
, vol.7
, pp. 815-836
-
-
Khan, A.R.1
James, M.N.2
-
32
-
-
67849094264
-
Slow thrombin is zymogen-like
-
Huntington JA. Slow thrombin is zymogen-like. J Thromb Haemost 2009; 7 (Suppl 1): 159-164.
-
(2009)
J Thromb Haemost
, vol.7
, Issue.SUPPL. 1
, pp. 159-164
-
-
Huntington, J.A.1
-
33
-
-
0017107996
-
Induction of the bovine trypsinogen-trypsin transition by peptides sequentially similar to the N-terminus of trypsin
-
Bode W, Huber R. Induction of the bovine trypsinogen-trypsin transition by peptides sequentially similar to the N-terminus of trypsin. FEBS Lett 1976; 68: 231-236.
-
(1976)
FEBS Lett
, vol.68
, pp. 231-236
-
-
Bode, W.1
Huber, R.2
-
34
-
-
28844468777
-
Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein
-
Tang J, Yu CL, Williams SR, et al. Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein. J Biol Chem 2005; 280: 41077-41089.
-
(2005)
J Biol Chem
, vol.280
, pp. 41077-41089
-
-
Tang, J.1
Yu, C.L.2
Williams, S.R.3
-
35
-
-
0036893122
-
Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2
-
Renne T, Sugiyama A, Gailani D, et al. Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2. Int Immunopharmacol 2002; 2: 1867-1873.
-
(2002)
Int Immunopharmacol
, vol.2
, pp. 1867-1873
-
-
Renne, T.1
Sugiyama, A.2
Gailani, D.3
-
36
-
-
0027155081
-
Mapping of the high molecular weight kininogen binding site of prekallikrein. Evidence for a discontinuous epitope formed by distinct segments of the prekallikrein heavy chain
-
Herwald H, Jahnen-Dechent W, Alla SA, et al. Mapping of the high molecular weight kininogen binding site of prekallikrein. Evidence for a discontinuous epitope formed by distinct segments of the prekallikrein heavy chain. J Biol Chem 1993; 268: 14527-14535.
-
(1993)
J Biol Chem
, vol.268
, pp. 14527-14535
-
-
Herwald, H.1
Jahnen-Dechent, W.2
Alla, S.A.3
-
37
-
-
0033520434
-
Mapping of the discontinuous H-kininogen binding site of plasma prekallikrein. Evidence for a critical role of apple domain-2
-
Renne T, Dedio J, Meijers JC, et al. Mapping of the discontinuous H-kininogen binding site of plasma prekallikrein. Evidence for a critical role of apple domain-2. J Biol Chem 1999; 274: 25777-25784.
-
(1999)
J Biol Chem
, vol.274
, pp. 25777-25784
-
-
Renne, T.1
Dedio, J.2
Meijers, J.C.3
-
38
-
-
0023257512
-
Primary structure requirements for the binding of human high molecular weight kininogen to plasma prekallikrein and factor XI
-
Tait JF, Fujikawa K. Primary structure requirements for the binding of human high molecular weight kininogen to plasma prekallikrein and factor XI. J Biol Chem 1987; 262: 11651-11656.
-
(1987)
J Biol Chem
, vol.262
, pp. 11651-11656
-
-
Tait, J.F.1
Fujikawa, K.2
-
39
-
-
0025345587
-
Mapping of the prekallikrein-binding site of human H-kininogen by ligand screening of lambda gt11 expression libraries. Mimicking of the predicted binding site by anti-idiotypic antibodies
-
Vogel R, Kaufmann J, Chung DW, et al. Mapping of the prekallikrein-binding site of human H-kininogen by ligand screening of lambda gt11 expression libraries. Mimicking of the predicted binding site by anti-idiotypic antibodies. J Biol Chem 1990; 265: 12494-12502.
-
(1990)
J Biol Chem
, vol.265
, pp. 12494-12502
-
-
Vogel, R.1
Kaufmann, J.2
Chung, D.W.3
-
40
-
-
0015251714
-
Plasma prekallikrein: Isolation, characterization, and mechanism of activation
-
Wuepper KD, Cochrane CG. Plasma prekallikrein: isolation, characterization, and mechanism of activation. J Exp Med 1972; 135: 1-20.
-
(1972)
J Exp Med
, vol.135
, pp. 1-20
-
-
Wuepper, K.D.1
Cochrane, C.G.2
-
41
-
-
0023201944
-
The coagulation-kinin pathway of human plasma
-
Kaplan AP, Silverberg M. The coagulation-kinin pathway of human plasma. Blood 1987; 70: 1-15.
-
(1987)
Blood
, vol.70
, pp. 1-15
-
-
Kaplan, A.P.1
Silverberg, M.2
-
42
-
-
33744927154
-
Crystal structure of the factor XI zymogen reveals a pathway for transactivation
-
Papagrigoriou E, McEwan PA, Walsh PN, et al. Crystal structure of the factor XI zymogen reveals a pathway for transactivation. Nat Struct Mol Biol 2006; 13: 557-558.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 557-558
-
-
Papagrigoriou, E.1
McEwan, P.A.2
Walsh, P.N.3
-
43
-
-
0028200808
-
The shape of high molecular weight kininogen. Organization into structural domains, changes with activation, and interactions with prekallikrein, as determined by electron microscopy
-
Weisel JW, Nagaswami C, Woodhead JL, et al. The shape of high molecular weight kininogen. Organization into structural domains, changes with activation, and interactions with prekallikrein, as determined by electron microscopy. J Biol Chem 1994; 269: 10100-10106.
-
(1994)
J Biol Chem
, vol.269
, pp. 10100-10106
-
-
Weisel, J.W.1
Nagaswami, C.2
Woodhead, J.L.3
-
44
-
-
0037124049
-
Identification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator
-
Shariat-Madar Z, Mahdi F, Schmaier AH. Identification and characterization of prolylcarboxypeptidase as an endothelial cell prekallikrein activator. J Biol Chem 2002; 277: 17962-17969.
-
(2002)
J Biol Chem
, vol.277
, pp. 17962-17969
-
-
Shariat-Madar, Z.1
Mahdi, F.2
Schmaier, A.H.3
-
45
-
-
84866648508
-
Influence of a Novel Inhibitor (UM8190) of Prolylcarboxypeptidase (PRCP) on Appetite and Thrombosis
-
Rabey FM, Gadepalli RS, Diano S, et al. Influence of a Novel Inhibitor (UM8190) of Prolylcarboxypeptidase (PRCP) on Appetite and Thrombosis. Curr Med Chem 2012; 19: 4194-4206.
-
(2012)
Curr Med Chem
, vol.19
, pp. 4194-4206
-
-
Rabey, F.M.1
Gadepalli, R.S.2
Diano, S.3
-
46
-
-
77950978248
-
Structure and function of factor XI
-
Emsley J, McEwan PA, Gailani D. Structure and function of factor XI. Blood 2010; 115: 2569-2577.
-
(2010)
Blood
, vol.115
, pp. 2569-2577
-
-
Emsley, J.1
McEwan, P.A.2
Gailani, D.3
-
47
-
-
0030899507
-
Factor IX activation by factor XIa proceeds without release of a free intermediate
-
Wolberg AS, Morris DP, Stafford DW. Factor IX activation by factor XIa proceeds without release of a free intermediate. Biochemistry 1997; 36: 4074-4079.
-
(1997)
Biochemistry
, vol.36
, pp. 4074-4079
-
-
Wolberg, A.S.1
Morris, D.P.2
Stafford, D.W.3
-
48
-
-
35648937607
-
Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation
-
Samuel D, Cheng H, Riley PW, et al. Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation. Proc Natl Acad Sci USA 2007; 104: 15693-15698.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15693-15698
-
-
Samuel, D.1
Cheng, H.2
Riley, P.W.3
-
49
-
-
84868603189
-
Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation
-
Langhauser F, Gob E, Kraft P, et al. Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation. Blood 2012; 120: 4082-4092.
-
(2012)
Blood
, vol.120
, pp. 4082-4092
-
-
Langhauser, F.1
Gob, E.2
Kraft, P.3
-
50
-
-
77950334578
-
Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time
-
Houlihan LM, Davies G, Tenesa A, et al. Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time. Am J Hum Genet 2010; 86: 626-631.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 626-631
-
-
Houlihan, L.M.1
Davies, G.2
Tenesa, A.3
-
51
-
-
79953685895
-
KNG1 Ile581Thr and susceptibility to venous thrombosis
-
Morange PE, Oudot-Mellakh T, Cohen W, et al. KNG1 Ile581Thr and susceptibility to venous thrombosis. Blood 2011; 117: 3692-3694.
-
(2011)
Blood
, vol.117
, pp. 3692-3694
-
-
Morange, P.E.1
Oudot-Mellakh, T.2
Cohen, W.3
-
52
-
-
84869203481
-
Targeting the kallikrein-related peptidases for drug development
-
Sotiropoulou G, Pampalakis G. Targeting the kallikrein-related peptidases for drug development. Trends Pharmacol Sci 2012; 33: 623-634.
-
(2012)
Trends Pharmacol Sci
, vol.33
, pp. 623-634
-
-
Sotiropoulou, G.1
Pampalakis, G.2
-
53
-
-
80051794851
-
Factor XI and XII as antithrombotic targets
-
Muller F, Gailani D, Renne T. Factor XI and XII as antithrombotic targets. Curr Opin Hematol 2011; 18: 349-355.
-
(2011)
Curr Opin Hematol
, vol.18
, pp. 349-355
-
-
Muller, F.1
Gailani, D.2
Renne, T.3
|