Enzymatic action of prostate-specific antigen (PSA or hK3): Substrate specificity and regulation by Zn2+, a tight-binding inhibitor

Prostate

Volumn 45, Issue 2, 2000, Pages 132-139

  Malm, Johan ^a   Hellman, Jukka ^b   Hogg, Phil ^c   Lilja, Hans ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF TURKU   (Finland)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Kallikrein; Prostate specific antigen; Semenogelin; Substrate specificity; Zinc

Indexed keywords

ARGININE; ASPARAGINE; ASPARTIC ACID; CHROMOGENIC SUBSTRATE; CHYMOTRYPSIN; GLUTAMINE; HISTIDINE; KALLIKREIN; LEUCINE; LYSINE; METHIONINE; PHENYLALANINE; PROSTATE PROTEIN; PROSTATE SPECIFIC ANTIGEN; SEMENOGELIN I; SEMENOGELIN II; SERINE; TISSUE KALLIKREIN; TRYPSIN; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; ZINC ION;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; EJACULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME REGULATION; ENZYME SPECIFICITY; HUMAN; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; REPRODUCTION; SPERMATOZOON MOTILITY;

ALPHA 1-ANTICHYMOTRYPSIN; AMINO ACID SEQUENCE; CATIONS, DIVALENT; ENZYME INHIBITORS; ENZYMES; HUMAN; HYDROLYSIS; MOLECULAR SEQUENCE DATA; PROSTATE-SPECIFIC ANTIGEN; SEMEN; SEQUENCE HOMOLOGY, AMINO ACID; SEX HORMONES; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; ZINC;

EID: 0033814795     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0045(20001001)45:2<132::AID-PROS7>3.0.CO;2-3     Document Type: Article

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