Critical role of organic anion transporters 1 and 3 in kidney accumulation and toxicity of aristolochic acid i

Molecular Pharmaceutics

Volumn 8, Issue 6, 2011, Pages 2183-2192

  Xue, Xiang ^a   Gong, Li Kun ^a   Maeda, Kazuya ^b   Luan, Yang ^a   Qi, Xin Ming ^a   Sugiyama, Yuichi ^b   Ren, Jin ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

aristolochic acid nephropathy; kidney toxicity; Oat1 and 3 knockout mice; organic anion transporter

Indexed keywords

ARISTOLOCHIC ACID; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 3; PROBENECID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG TRANSPORT; HUMAN; HUMAN CELL; KIDNEY TUBULE EPITHELIUM; KNOCKOUT MOUSE; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RENAL PROTECTION; URINARY EXCRETION; WILD TYPE;

ANIMALS; ARISTOLOCHIC ACIDS; HEK293 CELLS; HUMANS; KIDNEY; KIDNEY DISEASES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MUTAGENS; ORGANIC ANION TRANSPORT PROTEIN 1; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; TIME FACTORS;

EID: 82955169689     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp100418u     Document Type: Article

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