A novel homology model of TRPC3 reveals allosteric coupling between gate and selectivity filter

Cell Calcium

Volumn 54, Issue 3, 2013, Pages 175-185

  Lichtenegger, Michaela ^a   Stockner, Thomas ^b   Poteser, Michael ^d   Schleifer, Hannes ^d   Platzer, Dieter ^d   Romanin, Christoph ^c   Groschner, Klaus ^d  

^a UNIVERSITY OF GRAZ   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

^d MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Gating; Homology modeling; Selectivity; TRPC3

Indexed keywords

CALCIUM ION; CYSTEINE; ISOLEUCINE; RUTHENIUM RED; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; VOLTAGE GATED SODIUM CHANNEL;

ALLOSTERISM; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARCOBACTER; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; CROSS LINKING; CYTOSOL; GENE MUTATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; MEMBRANE PERMEABILITY; MOLECULAR MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURAL HOMOLOGY;

ARCOBACTER BUTZLERI;

1,2-BIS(O-AMINOPHENOXY)ETHANE-N,N,N′,N′-TETRAACETIC ACID; 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL; BAPTA; DAG; DIACYLGLYCEROL; G PROTEIN COUPLED RECEPTOR; GATING; GPCR; HOMOLOGY MODELING; PHOSPHOLIPASE C; PLC; SAG; SELECTIVITY; TRPC3;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ARCOBACTER; CALCIUM; CALCIUM SIGNALING; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; RUTHENIUM RED; STATIC ELECTRICITY; TRPC CATION CHANNELS;

EID: 84883241076     PISSN: 01434160     EISSN: 15321991     Source Type: Journal    
DOI: 10.1016/j.ceca.2013.05.010     Document Type: Article

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