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Volumn 110, Issue 3, 2013, Pages 450-457

Kallikrein-related peptidases (KLKs) in gastrointestinal cancer: Mechanistic and clinical aspects

Author keywords

Colorectal cancer; Gastric cancer; Kallikrein splice variants; Molecular tumour markers; Pancreatic carcinoma

Indexed keywords

BIOLOGICAL MARKER; KALLIKREIN 1; KALLIKREIN 10; KALLIKREIN 11; KALLIKREIN 12; KALLIKREIN 13; KALLIKREIN 15; KALLIKREIN 4; KALLIKREIN 5; KALLIKREIN 6; KALLIKREIN RELATED PEPTIDASE; NEUROPSIN; SERINE PROTEINASE; STRATUM CORNEUM CHYMOTRYPTIC ENZYME; UNCLASSIFIED DRUG;

EID: 84883240236     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH12-11-0791     Document Type: Article
Times cited : (38)

References (62)
  • 2
    • 0034159946 scopus 로고    scopus 로고
    • The new human kallikrein gene family: Implications in carcinogenesis
    • Diamandis EP, Yousef GM, Luo LY, et al. The new human kallikrein gene family: implications in carcinogenesis. Trends Endocrinol Metab 2000; 11: 54-60.
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 54-60
    • Diamandis, E.P.1    Yousef, G.M.2    Luo, L.Y.3
  • 3
    • 0035018273 scopus 로고    scopus 로고
    • The new human tissue kallikrein gene family: Structure, function, and association to disease
    • Yousef GM, Diamandis EP. The new human tissue kallikrein gene family: structure, function, and association to disease. Endocr Rev 2001; 22: 184-204.
    • (2001) Endocr Rev , vol.22 , pp. 184-204
    • Yousef, G.M.1    Diamandis, E.P.2
  • 4
    • 3042750282 scopus 로고    scopus 로고
    • The tissue kallikrein family of serine proteases: Functional roles in human disease and potential as clinical biomarkers
    • Clements JA, Willemsen NM, Myers SA, et al. The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers. Crit Rev Clin Lab Sci 2004; 41: 265-312.
    • (2004) Crit Rev Clin Lab Sci , vol.41 , pp. 265-312
    • Clements, J.A.1    Willemsen, N.M.2    Myers, S.A.3
  • 5
    • 34547634419 scopus 로고    scopus 로고
    • Distribution of 15 human kallikreins in tissues and biological fluids
    • Shaw JL, Diamandis EP. Distribution of 15 human kallikreins in tissues and biological fluids. Clin Chem 2007; 53: 1423-1432.
    • (2007) Clin Chem , vol.53 , pp. 1423-1432
    • Shaw, J.L.1    Diamandis, E.P.2
  • 6
    • 3543150203 scopus 로고    scopus 로고
    • Human tissue kallikreins: Physiologic roles and applications in cancer
    • Borgono CA, Michael IP, Diamandis EP. Human tissue kallikreins: physiologic roles and applications in cancer. Mol Cancer Res 2004; 2: 257-280.
    • (2004) Mol Cancer Res , vol.2 , pp. 257-280
    • Borgono, C.A.1    Michael, I.P.2    Diamandis, E.P.3
  • 7
    • 8144222388 scopus 로고    scopus 로고
    • The emerging roles of human tissue kallikreins in cancer
    • Borgono CA, Diamandis EP. The emerging roles of human tissue kallikreins in cancer. Nat Rev Cancer 2004; 4: 876-890.
    • (2004) Nat Rev Cancer , vol.4 , pp. 876-890
    • Borgono, C.A.1    Diamandis, E.P.2
  • 8
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-2917.
    • (2010) Int J Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3
  • 9
    • 77952873354 scopus 로고    scopus 로고
    • Kallikrein-related peptidase genes as promising biomarkers for prognosis and monitoring of human malignancies
    • Avgeris M, Mavridis K, Scorilas A. Kallikrein-related peptidase genes as promising biomarkers for prognosis and monitoring of human malignancies. Biol Chem 2010; 391: 505-511.
    • (2010) Biol Chem , vol.391 , pp. 505-511
    • Avgeris, M.1    Mavridis, K.2    Scorilas, A.3
  • 10
    • 84856242223 scopus 로고    scopus 로고
    • Kallikrein-related peptidases (KLKs) as novel potential biomarkers in gastric cancer: An open yet challenging road lies ahead
    • Scorilas A, Mavridis K. Kallikrein-related peptidases (KLKs) as novel potential biomarkers in gastric cancer: An open yet challenging road lies ahead. J Surg Oncol 2012; 105: 223-224.
    • (2012) J Surg Oncol , vol.105 , pp. 223-224
    • Scorilas, A.1    Mavridis, K.2
  • 12
    • 26444457406 scopus 로고    scopus 로고
    • Clinicopathologic and biological significance of kallikrein 6 overexpression in human gastric cancer
    • Nagahara H, Mimori K, Utsunomiya T, et al. Clinicopathologic and biological significance of kallikrein 6 overexpression in human gastric cancer. Clin Cancer Res 2005; 11: 6800-6806.
    • (2005) Clin Cancer Res , vol.11 , pp. 6800-6806
    • Nagahara, H.1    Mimori, K.2    Utsunomiya, T.3
  • 13
    • 84863585880 scopus 로고    scopus 로고
    • Upregulation and secretion of kallikrein-related peptidase 6 (KLK6) in gastric cancer
    • Kim JJ, Kim JT, Yoon HR, et al. Upregulation and secretion of kallikrein-related peptidase 6 (KLK6) in gastric cancer. Tumour Biol 2012; 33: 731-738.
    • (2012) Tumour Biol , vol.33 , pp. 731-738
    • Kim, J.J.1    Kim, J.T.2    Yoon, H.R.3
  • 14
    • 79955756238 scopus 로고    scopus 로고
    • Genomic and genetic alterations influence the progression of gastric cancer
    • Nobili S, Bruno L, Landini I, et al. Genomic and genetic alterations influence the progression of gastric cancer. World J Gastroenterol 2011; 17: 290-299.
    • (2011) World J Gastroenterol , vol.17 , pp. 290-299
    • Nobili, S.1    Bruno, L.2    Landini, I.3
  • 15
    • 0034769317 scopus 로고    scopus 로고
    • Comparison of tissue kallikrein and kinin receptor expression in gastric ulcers and neoplasms
    • Sawant S, Snyman C, Bhoola K. Comparison of tissue kallikrein and kinin receptor expression in gastric ulcers and neoplasms. Int Immunopharmacol 2001; 1: 2063-2080.
    • (2001) Int Immunopharmacol , vol.1 , pp. 2063-2080
    • Sawant, S.1    Snyman, C.2    Bhoola, K.3
  • 16
    • 37549012221 scopus 로고    scopus 로고
    • Kallikrein-binding protein inhibits growth of gastric carcinoma by reducing vascular endothelial growth factor production and angiogenesis
    • Zhu B, Lu L, Cai W, et al. Kallikrein-binding protein inhibits growth of gastric carcinoma by reducing vascular endothelial growth factor production and angiogenesis. Mol Cancer Ther 2007; 6: 3297-3306.
    • (2007) Mol Cancer Ther , vol.6 , pp. 3297-3306
    • Zhu, B.1    Lu, L.2    Cai, W.3
  • 17
    • 34247096035 scopus 로고    scopus 로고
    • Downregulation and CpG island hypermethylation of NES1/hK10 gene in the pathogenesis of human gastric cancer
    • Huang W, Zhong J, Wu LY, et al. Downregulation and CpG island hypermethylation of NES1/hK10 gene in the pathogenesis of human gastric cancer. Cancer Lett 2007; 251: 78-85.
    • (2007) Cancer Lett , vol.251 , pp. 78-85
    • Huang, W.1    Zhong, J.2    Wu, L.Y.3
  • 18
    • 63449115326 scopus 로고    scopus 로고
    • Suppression of gastric cancer growth by baculovirus vector-mediated transfer of normal epithelial cell specific-1 gene
    • Huang W, Tian XL, Wu YL, et al. Suppression of gastric cancer growth by baculovirus vector-mediated transfer of normal epithelial cell specific-1 gene. World J Gastroenterol 2008; 14: 5810-5815.
    • (2008) World J Gastroenterol , vol.14 , pp. 5810-5815
    • Huang, W.1    Tian, X.L.2    Wu, Y.L.3
  • 19
    • 33747607473 scopus 로고    scopus 로고
    • Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer
    • Feng B, Xu WB, Zheng MH, et al. Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer. J Gastroenterol Hepatol 2006; 21: 1596-1603.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 1596-1603
    • Feng, B.1    Xu, W.B.2    Zheng, M.H.3
  • 20
    • 79952442827 scopus 로고    scopus 로고
    • Over-expression of Ephb4 is associated with carcinogenesis of gastric cancer
    • Li M, Zhao ZW, Zhang Y, et al. Over-expression of Ephb4 is associated with carcinogenesis of gastric cancer. Dig Dis Sci 2011; 56: 698-706.
    • (2011) Dig Dis Sci , vol.56 , pp. 698-706
    • Li, M.1    Zhao, Z.W.2    Zhang, Y.3
  • 21
    • 24144491588 scopus 로고    scopus 로고
    • Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker
    • Yousef GM, White NM, Michael IP, et al. Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker. Tumour Biol 2005; 26: 227-235.
    • (2005) Tumour Biol , vol.26 , pp. 227-235
    • Yousef, G.M.1    White, N.M.2    Michael, I.P.3
  • 22
    • 84873889974 scopus 로고    scopus 로고
    • Clinical significance of human kallikrein 12 gene expression in gastric cancer
    • Zhao EH, Shen ZY, Liu H, et al. Clinical significance of human kallikrein 12 gene expression in gastric cancer. World J Gastroenterol 2012; 18: 6597-6604.
    • (2012) World J Gastroenterol , vol.18 , pp. 6597-6604
    • Zhao, E.H.1    Shen, Z.Y.2    Liu, H.3
  • 23
    • 84859810060 scopus 로고    scopus 로고
    • Kallikrein-related peptidases in prostate, breast, and ovarian cancers: From pathobiology to clinical relevance
    • Avgeris M, Mavridis K, Scorilas A. Kallikrein-related peptidases in prostate, breast, and ovarian cancers: from pathobiology to clinical relevance. Biol Chem 2012; 393: 301-317.
    • (2012) Biol Chem , vol.393 , pp. 301-317
    • Avgeris, M.1    Mavridis, K.2    Scorilas, A.3
  • 24
    • 77952487860 scopus 로고    scopus 로고
    • Prognostic value and biological role of the kallikrein-related peptidases in human malignancies
    • Mavridis K, Scorilas A. Prognostic value and biological role of the kallikrein-related peptidases in human malignancies. Future Oncol 2010; 6: 269-285.
    • (2010) Future Oncol , vol.6 , pp. 269-285
    • Mavridis, K.1    Scorilas, A.2
  • 25
    • 11444269896 scopus 로고    scopus 로고
    • In silico analysis of the human kallikrein gene 6
    • Yousef GM, Borgono CA, White NM, et al. In silico analysis of the human kallikrein gene 6. Tumour Biol 2004; 25: 282-289.
    • (2004) Tumour Biol , vol.25 , pp. 282-289
    • Yousef, G.M.1    Borgono, C.A.2    White, N.M.3
  • 26
    • 16644382983 scopus 로고    scopus 로고
    • Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity
    • Shinmura K, Tao H, Yamada H, et al. Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity. Human mutation 2004; 24: 273-274.
    • (2004) Human mutation , vol.24 , pp. 273-274
    • Shinmura, K.1    Tao, H.2    Yamada, H.3
  • 27
    • 77956714174 scopus 로고    scopus 로고
    • Kallikrein-related peptidase 13 (KLK13) gene expressional status contributes significantly in the prognosis of primary gastric carcinomas
    • Konstantoudakis G, Florou D, Mavridis K, et al. Kallikrein-related peptidase 13 (KLK13) gene expressional status contributes significantly in the prognosis of primary gastric carcinomas. Clin Biochem 2010; 43: 1205-1211.
    • (2010) Clin Biochem , vol.43 , pp. 1205-1211
    • Konstantoudakis, G.1    Florou, D.2    Mavridis, K.3
  • 28
    • 84873108267 scopus 로고    scopus 로고
    • The kallikrein-related peptidase 13 (KLK13) gene is substantially up-regulated after exposure of gastric cancer cells to antineoplastic agents
    • Florou D, Mavridis K, Scorilas A. The kallikrein-related peptidase 13 (KLK13) gene is substantially up-regulated after exposure of gastric cancer cells to antineoplastic agents. Tumour Biol 2012; 33: 2069-2078.
    • (2012) Tumour Biol , vol.33 , pp. 2069-2078
    • Florou, D.1    Mavridis, K.2    Scorilas, A.3
  • 29
    • 80052474106 scopus 로고    scopus 로고
    • Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry
    • Wen YG, Wang Q, Zhou CZ, et al. Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry. J Surg Oncol 2011; 104: 516-524.
    • (2011) J Surg Oncol , vol.104 , pp. 516-524
    • Wen, Y.G.1    Wang, Q.2    Zhou, C.Z.3
  • 30
    • 47549086134 scopus 로고    scopus 로고
    • Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs)
    • Ramsay AJ, Reid JC, Adams MN, et al. Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs). Biol Chem 2008; 389: 653-668.
    • (2008) Biol Chem , vol.389 , pp. 653-668
    • Ramsay, A.J.1    Reid, J.C.2    Adams, M.N.3
  • 32
    • 14644433095 scopus 로고    scopus 로고
    • Physiology and pathophysiology of proteinase-activated receptors (PARs): PAR-2-mediated proliferation of colon cancer cell
    • Nishibori M, Mori S, Takahashi HK. Physiology and pathophysiology of proteinase-activated receptors (PARs): PAR-2-mediated proliferation of colon cancer cell. J Pharmacol Sci 2005; 97: 25-30.
    • (2005) J Pharmacol Sci , vol.97 , pp. 25-30
    • Nishibori, M.1    Mori, S.2    Takahashi, H.K.3
  • 33
    • 84864917801 scopus 로고    scopus 로고
    • Kallikrein protease activated receptor (PAR) axis: An attractive target for drug development
    • Caliendo G, Santagada V, Perissutti E, et al. Kallikrein protease activated receptor (PAR) axis: an attractive target for drug development. J Med Chem 2012; 55: 6669-6686.
    • (2012) J Med Chem , vol.55 , pp. 6669-6686
    • Caliendo, G.1    Santagada, V.2    Perissutti, E.3
  • 34
    • 77749245859 scopus 로고    scopus 로고
    • Kallikrein-related peptidase 4: A new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells
    • Gratio V, Beaufort N, Seiz L, et al. Kallikrein-related peptidase 4: a new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells. Am J Pathol 2010; 176: 1452-1461.
    • (2010) Am J Pathol , vol.176 , pp. 1452-1461
    • Gratio, V.1    Beaufort, N.2    Seiz, L.3
  • 35
    • 80055003183 scopus 로고    scopus 로고
    • Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signalling pathway in colon cancer cells
    • Gratio V, Loriot C, Virca GD, et al. Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signalling pathway in colon cancer cells. Am J Pathol 2011; 179: 2625-2636.
    • (2011) Am J Pathol , vol.179 , pp. 2625-2636
    • Gratio, V.1    Loriot, C.2    Virca, G.D.3
  • 36
    • 84868707366 scopus 로고    scopus 로고
    • Kallikrein-related peptidases (KLKs): A gene family of novel cancer biomarkers
    • Kontos CK, Scorilas A. Kallikrein-related peptidases (KLKs): a gene family of novel cancer biomarkers. Clin Chem Lab Med 2012; 50: 1877-1891.
    • (2012) Clin Chem Lab Med , vol.50 , pp. 1877-1891
    • Kontos, C.K.1    Scorilas, A.2
  • 37
    • 67349241440 scopus 로고    scopus 로고
    • The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer
    • Talieri M, Li L, Zheng Y, et al. The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer. Br J Cancer 2009; 100: 1659-1665.
    • (2009) Br J Cancer , vol.100 , pp. 1659-1665
    • Talieri, M.1    Li, L.2    Zheng, Y.3
  • 38
    • 77949269635 scopus 로고    scopus 로고
    • Over-expression of human kallikrein 11 is associated with poor prognosis in patients with low rectal carcinoma
    • Yu X, Tang HY, Li XR, et al. Over-expression of human kallikrein 11 is associated with poor prognosis in patients with low rectal carcinoma. Med Oncol 2010; 27: 40-44.
    • (2010) Med Oncol , vol.27 , pp. 40-44
    • Yu, X.1    Tang, H.Y.2    Li, X.R.3
  • 39
    • 84875955183 scopus 로고    scopus 로고
    • Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7 & KLK14) in colon cancer
    • Devetzi M, Trangas T, Scorilas A, et al. Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7 & KLK14) in colon cancer. Thromb Haemost 2013; 109: 716-725.
    • (2013) Thromb Haemost , vol.109 , pp. 716-725
    • Devetzi, M.1    Trangas, T.2    Scorilas, A.3
  • 40
    • 80052340201 scopus 로고    scopus 로고
    • Expression analysis and clinical evaluation of kallikrein-related peptidase 10 (KLK10) in colorectal cancer
    • Talieri M, Alexopoulou DK, Scorilas A, et al. Expression analysis and clinical evaluation of kallikrein-related peptidase 10 (KLK10) in colorectal cancer. Tumour Biol 2011; 32: 737-744.
    • (2011) Tumour Biol , vol.32 , pp. 737-744
    • Talieri, M.1    Alexopoulou, D.K.2    Scorilas, A.3
  • 41
    • 17144391833 scopus 로고    scopus 로고
    • Clinical significance of human kallikrein gene 6 messenger RNA expression in colorectal cancer
    • Ogawa K, Utsunomiya T, Mimori K, et al. Clinical significance of human kallikrein gene 6 messenger RNA expression in colorectal cancer. Clin Cancer Res 2005; 11: 2889-2893.
    • (2005) Clin Cancer Res , vol.11 , pp. 2889-2893
    • Ogawa, K.1    Utsunomiya, T.2    Mimori, K.3
  • 42
    • 77749295455 scopus 로고    scopus 로고
    • Quantitative expression analysis and prognostic significance of KLK4 mRNA expression in colon cancer
    • In: Schmitt M, Fritz H, Sommerhoff CP, et al., editors. Munich, Germany: Hieronymus Druck und Verlag
    • Kontos CK, Chantzis D, Papadopoulos IN, et al. Quantitative expression analysis and prognostic significance of KLK4 mRNA expression in colon cancer. In: Schmitt M, Fritz H, Sommerhoff CP, et al., editors. 3rd International Symposium on Kallikreins and Kallikrein-Related Peptidases 2009 August 30-September 2, 2009; Munich, Germany: Hieronymus Druck und Verlag; 2009. p. 86.
    • (2009) 3rd International Symposium on Kallikreins and Kallikrein-Related Peptidases 2009 August 30-September 2, 2009 , pp. 86
    • Kontos, C.K.1    Chantzis, D.2    Papadopoulos, I.N.3
  • 43
    • 84872877336 scopus 로고    scopus 로고
    • Kallikrein-related peptidase 4 (KLK4) mRNA predicts short-term relapse in colorectal adenocarcinoma patients
    • Kontos CK, Chantzis D, Papadopoulos IN, et al. Kallikrein-related peptidase 4 (KLK4) mRNA predicts short-term relapse in colorectal adenocarcinoma patients. Cancer Lett 2013; 330: 106-112.
    • (2013) Cancer Lett , vol.330 , pp. 106-112
    • Kontos, C.K.1    Chantzis, D.2    Papadopoulos, I.N.3
  • 44
    • 62549113142 scopus 로고    scopus 로고
    • Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer
    • Talieri M, Mathioudaki K, Prezas P, et al. Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer. Thromb Haemost 2009; 101: 741-747.
    • (2009) Thromb Haemost , vol.101 , pp. 741-747
    • Talieri, M.1    Mathioudaki, K.2    Prezas, P.3
  • 45
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta LA, Kohn EC. The microenvironment of the tumour-host interface. Nature 2001; 411: 375-379.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 46
    • 34247597726 scopus 로고    scopus 로고
    • Kallikrein 7 enhances pancreatic cancer cell invasion by shedding E-cadherin
    • Johnson SK, Ramani VC, Hennings L, et al. Kallikrein 7 enhances pancreatic cancer cell invasion by shedding E-cadherin. Cancer 2007; 109: 1811-1820.
    • (2007) Cancer , vol.109 , pp. 1811-1820
    • Johnson, S.K.1    Ramani, V.C.2    Hennings, L.3
  • 47
    • 41149167016 scopus 로고    scopus 로고
    • The extracellular matrix protein fibronectin is a substrate for kallikrein 7
    • Ramani VC, Haun RS. The extracellular matrix protein fibronectin is a substrate for kallikrein 7. Biochem Biophys Res Commun 2008; 369: 1169-1173.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 1169-1173
    • Ramani, V.C.1    Haun, R.S.2
  • 48
    • 84862950995 scopus 로고    scopus 로고
    • alpha2 Integrin-Dependent Suppression of Pancreatic Adenocarcinoma Cell Invasion Involves Ectodomain Regulation of Kallikrein-Related Peptidase-5
    • Lee CY, Marzan D, Lin G, et al. alpha2 Integrin-Dependent Suppression of Pancreatic Adenocarcinoma Cell Invasion Involves Ectodomain Regulation of Kallikrein-Related Peptidase-5. J Oncol 2011; 2011: 365651.
    • (2011) J Oncol , vol.2011 , pp. 365651
    • Lee, C.Y.1    Marzan, D.2    Lin, G.3
  • 49
    • 58749093593 scopus 로고    scopus 로고
    • Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer
    • Ramani VC, Hennings L, Haun RS. Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer. BMC Cancer 2008; 8: 373.
    • (2008) BMC Cancer , vol.8 , pp. 373
    • Ramani, V.C.1    Hennings, L.2    Haun, R.S.3
  • 50
    • 0028691011 scopus 로고
    • Loss of membranous E-cadherin expression in pancreatic cancer: Correlation with lymph node metastasis, high grade, and advanced stage
    • Pignatelli M, Ansari TW, Gunter P, et al. Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade, and advanced stage. J Pathol 1994; 174: 243-248.
    • (1994) J Pathol , vol.174 , pp. 243-248
    • Pignatelli, M.1    Ansari, T.W.2    Gunter, P.3
  • 51
    • 34250365241 scopus 로고    scopus 로고
    • Desmosomes: A role in cancer?
    • Chidgey M, Dawson C. Desmosomes: a role in cancer? Br J Cancer 2007; 96: 1783-1787.
    • (2007) Br J Cancer , vol.96 , pp. 1783-1787
    • Chidgey, M.1    Dawson, C.2
  • 52
    • 0030715322 scopus 로고    scopus 로고
    • ECM and cell surface proteolysis: Regulating cellular ecology
    • Werb Z. ECM and cell surface proteolysis: regulating cellular ecology. Cell 1997; 91: 439-442.
    • (1997) Cell , vol.91 , pp. 439-442
    • Werb, Z.1
  • 53
    • 84863588450 scopus 로고    scopus 로고
    • Expression of kallikrein-related peptidase 7 predicts poor prognosis in patients with unresectable pancreatic ductal adenocarcinoma
    • Iakovlev V, Siegel ER, Tsao MS, et al. Expression of kallikrein-related peptidase 7 predicts poor prognosis in patients with unresectable pancreatic ductal adenocarcinoma. Cancer Epidemiol Biomarkers Prev 2012; 21: 1135-1142.
    • (2012) Cancer Epidemiol Biomarkers Prev , vol.21 , pp. 1135-1142
    • Iakovlev, V.1    Siegel, E.R.2    Tsao, M.S.3
  • 54
    • 9144241047 scopus 로고    scopus 로고
    • Highly expressed genes in pancreatic ductal adenocarcinomas: A comprehensive characterization and comparison of the transcription profiles obtained from three major technologies
    • Iacobuzio-Donahue CA, Ashfaq R, Maitra A, et al. Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies. Cancer Res 2003; 63: 8614-8622.
    • (2003) Cancer Res , vol.63 , pp. 8614-8622
    • Iacobuzio-Donahue, C.A.1    Ashfaq, R.2    Maitra, A.3
  • 55
    • 17844408229 scopus 로고    scopus 로고
    • Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression
    • Hustinx SR, Cao D, Maitra A, et al. Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression. Cancer Biol Ther 2004; 3: 1254-1261.
    • (2004) Cancer Biol Ther , vol.3 , pp. 1254-1261
    • Hustinx, S.R.1    Cao, D.2    Maitra, A.3
  • 56
    • 1442350559 scopus 로고    scopus 로고
    • In-silico analysis of kallikrein gene expression in pancreatic and colon cancers
    • Yousef GM, Borgono CA, Popalis C, et al. In-silico analysis of kallikrein gene expression in pancreatic and colon cancers. Anticancer Res 2004; 24: 43-51.
    • (2004) Anticancer Res , vol.24 , pp. 43-51
    • Yousef, G.M.1    Borgono, C.A.2    Popalis, C.3
  • 58
    • 84883209749 scopus 로고    scopus 로고
    • Expression pattern of the kallikreinrelated peptidase (KLK) gene family in normal and pathological human liver
    • In: Scorilas A, editor. Rhodes, Greece; 2011
    • Lavergne E, Petit-Courty A, Vallet A, et al. Expression pattern of the kallikreinrelated peptidase (KLK) gene family in normal and pathological human liver. In: Scorilas A, editor. 4th International Symposium on Kallikreins and Kallikrein-Related Peptidases; 2011; Rhodes, Greece; 2011.
    • (2011) 4th International Symposium on Kallikreins and Kallikrein-Related Peptidases
    • Lavergne, E.1    Petit-Courty, A.2    Vallet, A.3
  • 59
    • 70350236515 scopus 로고    scopus 로고
    • Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma
    • Lu CY, Hsieh SY, Lu YJ, et al. Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma. Genes Chromosomes Cancer 2009; 48: 1057-1068.
    • (2009) Genes Chromosomes Cancer , vol.48 , pp. 1057-1068
    • Lu, C.Y.1    Hsieh, S.Y.2    Lu, Y.J.3
  • 60
    • 34648825647 scopus 로고    scopus 로고
    • Kallikrein-binding protein suppresses growth of hepatocellular carcinoma by anti-angiogenic activity
    • Lu L, Yang Z, Zhu B, et al. Kallikrein-binding protein suppresses growth of hepatocellular carcinoma by anti-angiogenic activity. Cancer Lett 2007; 257: 97-106.
    • (2007) Cancer Lett , vol.257 , pp. 97-106
    • Lu, L.1    Yang, Z.2    Zhu, B.3
  • 61
    • 24644457254 scopus 로고    scopus 로고
    • Upregulation of tissue kallikrein, kinin B1 receptor, and kinin B2 receptor in mast and giant cells infiltrating oesophageal squamous cell carcinoma
    • Dlamini Z, Bhoola KD. Upregulation of tissue kallikrein, kinin B1 receptor, and kinin B2 receptor in mast and giant cells infiltrating oesophageal squamous cell carcinoma. J Clin Pathol 2005; 58: 915-922.
    • (2005) J Clin Pathol , vol.58 , pp. 915-922
    • Dlamini, Z.1    Bhoola, K.D.2
  • 62
    • 0032708778 scopus 로고    scopus 로고
    • Visualisation of tissue kallikrein and kinin receptors in oesophageal carcinoma
    • Dlamini Z, Raidoo D, Bhoola K. Visualisation of tissue kallikrein and kinin receptors in oesophageal carcinoma. Immunopharmacology 1999; 43: 303-310.
    • (1999) Immunopharmacology , vol.43 , pp. 303-310
    • Dlamini, Z.1    Raidoo, D.2    Bhoola, K.3


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