Kallikrein-related peptidases (KLKs) as novel potential biomarkers in gastric cancer: An open yet challenging road lies ahead

Journal of Surgical Oncology

Volumn 105, Issue 3, 2012, Pages 223-224

  Scorilas, Andreas ^a   Mavridis, Konstantinos ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CHYMOTRYPSIN; KALLIKREIN 6; MICRORNA; PROSTATE SPECIFIC ANTIGEN; PROTEINASE ACTIVATED RECEPTOR; PROUROKINASE; TRANSFORMING GROWTH FACTOR BETA;

CANCER CELL CULTURE; CANCER SCREENING; CHROMOSOME 19Q; EDITORIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; GENETIC TRANSFECTION; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIQUEFACTION; LOGISTIC REGRESSION ANALYSIS; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH CANCER; TUMOR VOLUME;

FEMALE; HUMANS; MALE; SERINE ENDOPEPTIDASES; STOMACH; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 84856242223     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.22041     Document Type: Editorial

References (8)

1. Mavridis K, Scorilas A,: Prognostic value and biological role of the kallikrein-related peptidases in human malignancies. Future Oncol 2010; 6: 269-285.
2. Konstantoudakis G, Florou D, Mavridis K, et al.: Kallikrein-related peptidase 13 (KLK13) gene expressional status contributes significantly in the prognosis of primary gastric carcinomas. Clin Biochem 2010; 43: 1205-1211.
3. Nagahara H, Mimori K, Utsunomiya T, et al.: Clinicopathologic and biological significance of kallikrein 6 overexpression in human gastric cancer. Clin Cancer Res 2005; 11: 6800-6806. (Pubitemid 41428734)
4. Feng B, Xu WB, Zheng MH, et al.: Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer. J Gastroenterol Hepatol 2006; 21: 1596-1603. (Pubitemid 44266521)
5. Huang W, Zhong J, Wu LY, et al.: Downregulation and CpG island hypermethylation of NES1/hK10 gene in the pathogenesis of human gastric cancer. Cancer Lett 2007; 251: 78-85. (Pubitemid 46589767)
6. Huang W, Tian XL, Wu YL, et al.: Suppression of gastric cancer growth by baculovirus vector-mediated transfer of normal epithelial cell specific-1 gene. World J Gastroenterol 2008; 14: 5810-5815.
7. Li M, Zhao ZW, Zhang Y, et al.: Over-expression of Ephb4 is associated with carcinogenesis of gastric cancer. Dig Dis Sci 2011; 56: 698-706.
8. Wen Y-G, Wang Q, Zhou C-Z, et al.: Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry. J Surg Oncol 2011; 104: 516-524. DOI: 10.1002/jso.2198.