메뉴 건너뛰기




Volumn 99, Issue 4, 2013, Pages 769-779

Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1

Author keywords

Atrial fibrillation; Cardiac fibrosis; Gene expression; Heart failure; Transforming growth factor beta1

Indexed keywords

RNA; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84883233816     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt074     Document Type: Article
Times cited : (90)

References (46)
  • 2
    • 60749123546 scopus 로고    scopus 로고
    • Prevention of atrial fibrillation: Report from a national heart, lung, and blood institute workshop
    • Benjamin EJ, Chen PS, Bild DE, Mascette AM, Albert CM, Alonso A et al. Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation 2009;119:606-618.
    • (2009) Circulation , vol.119 , pp. 606-618
    • Benjamin, E.J.1    Chen, P.S.2    Bild, D.E.3    Mascette, A.M.4    Albert, C.M.5    Alonso, A.6
  • 3
    • 41649102599 scopus 로고    scopus 로고
    • Differential behaviors of atrial versus ventricular fibroblasts: A potential role for platelet-derived growth factor in atrialventricular remodeling differences
    • Burstein B, Libby E, Calderone A, Nattel S. Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrialventricular remodeling differences. Circulation 2008;117:1630-1641.
    • (2008) Circulation , vol.117 , pp. 1630-1641
    • Burstein, B.1    Libby, E.2    Calderone, A.3    Nattel, S.4
  • 4
    • 0037050001 scopus 로고    scopus 로고
    • New ideas about atrial fibrillation 50 years on
    • Nattel S. New ideas about atrial fibrillation 50 years on. Nature 2002;415:219-226.
    • (2002) Nature , vol.415 , pp. 219-226
    • Nattel, S.1
  • 5
    • 33750223425 scopus 로고    scopus 로고
    • Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure
    • Lee KW, Everett TH 4th, Rahmutula D, Guerra JM, Wilson E, Ding C et al. Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure. Circulation 2006;114:1703-1712.
    • (2006) Circulation , vol.114 , pp. 1703-1712
    • Lee, K.W.1    Everett, I.V.T.H.2    Rahmutula, D.3    Guerra, J.M.4    Wilson, E.5    Ding, C.6
  • 6
    • 2942689981 scopus 로고    scopus 로고
    • Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1
    • Verheule S, Sato T, Everett T, Engle SK, Otten D, Rubart-von der Lohe M et al. Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1. Circ Res 2004;94:1458-1465.
    • (2004) Circ Res , vol.94 , pp. 1458-1465
    • Verheule, S.1    Sato, T.2    Everett, T.3    Engle, S.K.4    Otten, D.5    Rubart-Von Der Lohe, M.6
  • 7
    • 1642545563 scopus 로고    scopus 로고
    • Fibrosis in left atrial tissue of patients with atrial fibrillation with and without underlying mitral valve disease
    • Boldt A, Wetzel U, Lauschke J, Weigl J, Gummert J, Hindricks G et al. Fibrosis in left atrial tissue of patients with atrial fibrillation with and without underlying mitral valve disease. Heart 2004;90:400-405.
    • (2004) Heart , vol.90 , pp. 400-405
    • Boldt, A.1    Wetzel, U.2    Lauschke, J.3    Weigl, J.4    Gummert, J.5    Hindricks, G.6
  • 8
    • 3142646893 scopus 로고    scopus 로고
    • Differences in atrial versus ventricular remodeling in dogs with ventricular tachypacing-induced congestive heart failure
    • Hanna N, Cardin S, Leung TK, Nattel S. Differences in atrial versus ventricular remodeling in dogs with ventricular tachypacing-induced congestive heart failure. Cardiovasc Res 2004;63:236-244.
    • (2004) Cardiovasc Res , vol.63 , pp. 236-244
    • Hanna, N.1    Cardin, S.2    Leung, T.K.3    Nattel, S.4
  • 11
    • 65849479566 scopus 로고    scopus 로고
    • Plasma transforming growth factor beta1 as a biochemical marker to predict the persistence of atrial fibrillation after the surgical maze procedure
    • On YK, Jeon ES, Lee SY, Shin DH, Choi JO, Sung J et al. Plasma transforming growth factor beta1 as a biochemical marker to predict the persistence of atrial fibrillation after the surgical maze procedure. J Thorac Cardiovasc Surg 2009;137:1515-1520.
    • (2009) J Thorac Cardiovasc Surg , vol.137 , pp. 1515-1520
    • On, Y.K.1    Jeon, E.S.2    Lee, S.Y.3    Shin, D.H.4    Choi, J.O.5    Sung, J.6
  • 12
    • 71449087318 scopus 로고    scopus 로고
    • Clinical and serological predictors for the recurrence of atrial fibrillation after electrical cardioversion
    • Kim SK, Pak HN, Park JH, Ko KJ, Lee JS, Choi JI et al. Clinical and serological predictors for the recurrence of atrial fibrillation after electrical cardioversion. Europace 2009;11: 1632-1638.
    • (2009) Europace , vol.11 , pp. 1632-1638
    • Kim, S.K.1    Pak, H.N.2    Park, J.H.3    Ko, K.J.4    Lee, J.S.5    Choi, J.I.6
  • 13
    • 79954429830 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 (TGF-beta 1) in atrial fibrillation and acute congestive heart failure
    • Behnes M, Hoffmann U, Lang S, Weiss C, Ahmad-Nejad P, Neumaier M et al. Transforming growth factor beta 1 (TGF-beta 1) in atrial fibrillation and acute congestive heart failure. Clin Res Cardiol 2011;100:335-342.
    • (2011) Clin Res Cardiol , vol.100 , pp. 335-342
    • Behnes, M.1    Hoffmann, U.2    Lang, S.3    Weiss, C.4    Ahmad-Nejad, P.5    Neumaier, M.6
  • 14
    • 79952339833 scopus 로고    scopus 로고
    • High plasma concentrations of transforming growth factor-beta and tissue inhibitor of metalloproteinase-1: Potential non-invasive predictors for electroanatomical remodeling of atrium in patients with non-valvular atrial fibrillation
    • Kim SK, Park JH, Kim JY, Choi JI, Joung B, Lee MH et al. High plasma concentrations of transforming growth factor-beta and tissue inhibitor of metalloproteinase-1: potential non-invasive predictors for electroanatomical remodeling of atrium in patients with non-valvular atrial fibrillation. Circ J 2011;75:557-564.
    • (2011) Circ J , vol.75 , pp. 557-564
    • Kim, S.K.1    Park, J.H.2    Kim, J.Y.3    Choi, J.I.4    Joung, B.5    Lee, M.H.6
  • 15
  • 17
    • 0034677796 scopus 로고    scopus 로고
    • Atrial but not ventricular fibrosis in mice expressing a mutant transforming growth factorbeta( 1) transgene in the heart
    • Nakajima H, Nakajima HO, Salcher O, Dittie AS, Dembowsky K, Jing S et al. Atrial but not ventricular fibrosis in mice expressing a mutant transforming growth factorbeta( 1) transgene in the heart. Circ Res 2000;86:571-579.
    • (2000) Circ Res , vol.86 , pp. 571-579
    • Nakajima, H.1    Nakajima, H.O.2    Salcher, O.3    Dittie, A.S.4    Dembowsky, K.5    Jing, S.6
  • 18
    • 0028328817 scopus 로고
    • An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct
    • Abe M, Harpel JG, Metz CN, Nunes I, Loskutoff DJ, Rifkin DB. An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem 1994;216:276-284.
    • (1994) Anal Biochem , vol.216 , pp. 276-284
    • Abe, M.1    Harpel, J.G.2    Metz, C.N.3    Nunes, I.4    Loskutoff, D.J.5    Rifkin, D.B.6
  • 19
    • 0028810240 scopus 로고
    • Atrial natriuretic peptide suppresses the transcription of its guanylyl cyclase-linked receptor
    • Cao L, Wu J, Gardner DG. Atrial natriuretic peptide suppresses the transcription of its guanylyl cyclase-linked receptor. J Biol Chem 1995;270:24891-24897.
    • (1995) J Biol Chem , vol.270 , pp. 24891-24897
    • Cao, L.1    Wu, J.2    Gardner, D.G.3
  • 20
    • 33751328068 scopus 로고    scopus 로고
    • Ki26894, a novel transforming growth factor-beta type i receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line
    • Ehata S, Hanyu A, Fujime M, Katsuno Y, Fukunaga E, Goto K et al. Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line. Cancer Sci 2007;98: 127-133.
    • (2007) Cancer Sci , vol.98 , pp. 127-133
    • Ehata, S.1    Hanyu, A.2    Fujime, M.3    Katsuno, Y.4    Fukunaga, E.5    Goto, K.6
  • 21
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • Winer J, Jung CK, Shackel I, Williams PM. Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 1999;270:41-49.
    • (1999) Anal Biochem , vol.270 , pp. 41-49
    • Winer, J.1    Jung, C.K.2    Shackel, I.3    Williams, P.M.4
  • 22
    • 77957255499 scopus 로고    scopus 로고
    • Pirfenidone mitigates left ventricular fibrosis and dysfunction after myocardial infarction and reduces arrhythmias
    • Nguyen DT, Ding C, Wilson E, Marcus GM, Olgin JE. Pirfenidone mitigates left ventricular fibrosis and dysfunction after myocardial infarction and reduces arrhythmias. Heart Rhythm 2010;7:1438-1445.
    • (2010) Heart Rhythm , vol.7 , pp. 1438-1445
    • Nguyen, D.T.1    Ding, C.2    Wilson, E.3    Marcus, G.M.4    Olgin, J.E.5
  • 23
    • 0028274652 scopus 로고
    • Subthreshold stimulation of Purkinje fibers interrupts ventricular tachycardia in intact hearts. Experimental study with voltage-sensitive dyes and imaging techniques
    • Salama G, Kanai A, Efimov IR. Subthreshold stimulation of Purkinje fibers interrupts ventricular tachycardia in intact hearts. Experimental study with voltage-sensitive dyes and imaging techniques. Circ Res 1994;74:604-619.
    • (1994) Circ Res , vol.74 , pp. 604-619
    • Salama, G.1    Kanai, A.2    Efimov, I.R.3
  • 25
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004;3: Article3.
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 26
    • 0037024230 scopus 로고    scopus 로고
    • Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs
    • Shinagawa K, Shi YF, Tardif JC, Leung TK, Nattel S. Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs. Circulation 2002; 105:2672-2678.
    • (2002) Circulation , vol.105 , pp. 2672-2678
    • Shinagawa, K.1    Shi, Y.F.2    Tardif, J.C.3    Leung, T.K.4    Nattel, S.5
  • 27
    • 79451475323 scopus 로고    scopus 로고
    • Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia-mediated downregulation of Smad7
    • He X, Gao X, Peng L,Wang S, Zhu Y, Ma H et al. Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia-mediated downregulation of Smad7. Circ Res 2011;108:164-175.
    • (2011) Circ Res , vol.108 , pp. 164-175
    • He, X.1    Gao, X.2    Peng, L.3    Wang, S.4    Zhu, Y.5    Ma, H.6
  • 29
    • 0141839060 scopus 로고    scopus 로고
    • Electrical remodeling of the atria in congestive heart failure: Electrophysiological and electroanatomic mapping in humans
    • Sanders P, Morton JB, Davidson NC, Spence SJ, Vohra JK, Sparks PB et al. Electrical remodeling of the atria in congestive heart failure: electrophysiological and electroanatomic mapping in humans. Circulation 2003;108:1461-1468.
    • (2003) Circulation , vol.108 , pp. 1461-1468
    • Sanders, P.1    Morton, J.B.2    Davidson, N.C.3    Spence, S.J.4    Vohra, J.K.5    Sparks, P.B.6
  • 30
    • 0033529394 scopus 로고    scopus 로고
    • Promotion of atrial fibrillation by heart failure in dogs: Atrial remodeling of a different sort
    • Li D, Fareh S, Leung TK, Nattel S. Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort. Circulation 1999;100:87-95.
    • (1999) Circulation , vol.100 , pp. 87-95
    • Li, D.1    Fareh, S.2    Leung, T.K.3    Nattel, S.4
  • 31
    • 33845659664 scopus 로고    scopus 로고
    • Atrial electrical and structural abnormalities in an ovine model of chronic blood pressure elevation after prenatal corticosteroid exposure: Implications for development of atrial fibrillation
    • Kistler PM, Sanders P, Dodic M, Spence SJ, Samuel CS, Zhao C et al. Atrial electrical and structural abnormalities in an ovine model of chronic blood pressure elevation after prenatal corticosteroid exposure: implications for development of atrial fibrillation. Eur Heart J 2006;27:3045-3056.
    • (2006) Eur Heart J , vol.27 , pp. 3045-3056
    • Kistler, P.M.1    Sanders, P.2    Dodic, M.3    Spence, S.J.4    Samuel, C.S.5    Zhao, C.6
  • 32
    • 0035923479 scopus 로고    scopus 로고
    • Effects of angiotensinconverting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure
    • Li D, Shinagawa K, Pang L, Leung TK, Cardin S, Wang Z et al. Effects of angiotensinconverting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure. Circulation 2001; 104:2608-2614.
    • (2001) Circulation , vol.104 , pp. 2608-2614
    • Li, D.1    Shinagawa, K.2    Pang, L.3    Leung, T.K.4    Cardin, S.5    Wang, Z.6
  • 33
    • 1642539998 scopus 로고    scopus 로고
    • Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure
    • Cha TJ, Ehrlich JR, Zhang L, Shi YF, Tardif JC, Leung TK et al. Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure. Circulation 2004;109:412-418.
    • (2004) Circulation , vol.109 , pp. 412-418
    • Cha, T.J.1    Ehrlich, J.R.2    Zhang, L.3    Shi, Y.F.4    Tardif, J.C.5    Leung, T.K.6
  • 34
    • 38349098963 scopus 로고    scopus 로고
    • Interleukin-6 and atrial fibrillation in patients with coronary artery disease: Data from the Heart and Soul Study
    • Marcus GM, Whooley MA, Glidden DV, Pawlikowska L, Zaroff JG, Olgin JE. Interleukin-6 and atrial fibrillation in patients with coronary artery disease: data from the Heart and Soul Study. Am Heart J 2008;155:303-309.
    • (2008) Am Heart J , vol.155 , pp. 303-309
    • Marcus, G.M.1    Whooley, M.A.2    Glidden, D.V.3    Pawlikowska, L.4    Zaroff, J.G.5    Olgin, J.E.6
  • 35
    • 58149086016 scopus 로고    scopus 로고
    • Atrial gap junctions, NF-kappaB and fibrosis in patients undergoing coronary artery bypass surgery: The relationship with postoperative atrial fibrillation
    • Li JY, Lai YJ, Yeh HI, Chen CL, Sun S, Wu SJ et al. Atrial gap junctions, NF-kappaB and fibrosis in patients undergoing coronary artery bypass surgery: the relationship with postoperative atrial fibrillation. Cardiology 2009;112:81-88.
    • (2009) Cardiology , vol.112 , pp. 81-88
    • Li, J.Y.1    Lai, Y.J.2    Yeh, H.I.3    Chen, C.L.4    Sun, S.5    Wu, S.J.6
  • 36
    • 33847252976 scopus 로고    scopus 로고
    • Atrial fibrosis and the mechanisms of atrial fibrillation
    • Everett TH, Olgin JE. Atrial fibrosis and the mechanisms of atrial fibrillation. Heart Rhythm 2007;4:S24-S27.
    • (2007) Heart Rhythm , vol.4
    • Everett, T.H.1    Olgin, J.E.2
  • 37
    • 0037635434 scopus 로고    scopus 로고
    • Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: The Framingham Heart Study
    • Wang TJ, Larson MG, Levy D, Vasan RS, Leip EP,Wolf PA et al. Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study. Circulation 2003;107:2920-2925.
    • (2003) Circulation , vol.107 , pp. 2920-2925
    • Wang, T.J.1    Larson, M.G.2    Levy, D.3    Vasan, R.S.4    Leip, E.P.5    Wolf, P.A.6
  • 38
    • 35448992505 scopus 로고    scopus 로고
    • Mounting evidence that fibrosis generates a major mechanism for atrial fibrillation
    • Spach MS. Mounting evidence that fibrosis generates a major mechanism for atrial fibrillation. Circ Res 2007;101:743-745.
    • (2007) Circ Res , vol.101 , pp. 743-745
    • Spach, M.S.1
  • 39
    • 0031049517 scopus 로고    scopus 로고
    • Microfibrosis produces electrical load variations due to loss of side-to-side cell connections: A major mechanism of structural heart disease arrhythmias
    • Spach MS, Boineau JP. Microfibrosis produces electrical load variations due to loss of side-to-side cell connections: a major mechanism of structural heart disease arrhythmias. Pacing Clin Electrophysiol 1997;20:397-413.
    • (1997) Pacing Clin Electrophysiol , vol.20 , pp. 397-413
    • Spach, M.S.1    Boineau, J.P.2
  • 40
    • 10644262194 scopus 로고    scopus 로고
    • Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II
    • Chen K, Mehta JL, Li D, Joseph L, Joseph J. Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II. Circ Res 2004;95:1167-1173.
    • (2004) Circ Res , vol.95 , pp. 1167-1173
    • Chen, K.1    Mehta, J.L.2    Li, D.3    Joseph, L.4    Joseph, J.5
  • 41
    • 0036051343 scopus 로고    scopus 로고
    • Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
    • Abreu JG, Ketpura NI, Reversade B, De Robertis EM. Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat Cell Biol 2002;4:599-604.
    • (2002) Nat Cell Biol , vol.4 , pp. 599-604
    • Abreu, J.G.1    Ketpura, N.I.2    Reversade, B.3    De Robertis, E.M.4
  • 43
    • 0036838772 scopus 로고    scopus 로고
    • Pathogenesis of fibrosis: Role of TGF-beta and CTGF
    • Ihn H. Pathogenesis of fibrosis: role of TGF-beta and CTGF. Curr Opin Rheumatol 2002;14:681-685.
    • (2002) Curr Opin Rheumatol , vol.14 , pp. 681-685
    • Ihn, H.1
  • 44
    • 0442291674 scopus 로고    scopus 로고
    • The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology
    • Leask A, Abraham DJ. The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology. Biochem Cell Biol 2003;81:355-363.
    • (2003) Biochem Cell Biol , vol.81 , pp. 355-363
    • Leask, A.1    Abraham, D.J.2
  • 45
    • 12144290445 scopus 로고    scopus 로고
    • B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts: Fibrosis, myofibroblast conversion, proliferation, and inflammation
    • Kapoun AM, Liang F, O'Young G, Damm DL, Quon D, White RD et al. B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts: fibrosis, myofibroblast conversion, proliferation, and inflammation. Circ Res 2004;94:453-461.
    • (2004) Circ Res , vol.94 , pp. 453-461
    • Kapoun, A.M.1    Liang, F.2    O'Young, G.3    Damm, D.L.4    Quon, D.5    White, R.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.