-
1
-
-
79960796417
-
Exploiting drug-disease relationships for computational drug repositioning
-
Dudley, J. T.; Deshpande, T.; Butte, A. J. Exploiting drug-disease relationships for computational drug repositioning Briefings Bioinf. 2011, 12, 303-311
-
(2011)
Briefings Bioinf.
, vol.12
, pp. 303-311
-
-
Dudley, J.T.1
Deshpande, T.2
Butte, A.J.3
-
2
-
-
69549090088
-
Concept-based semi-automatic classification of drugs
-
Gurulingappa, H.; Kolarik, C.; Hofmann-Apitius, M.; Fluck, J. Concept-based semi-automatic classification of drugs J. Chem. Inf. Model. 2009, 49, 1986-1992
-
(2009)
J. Chem. Inf. Model.
, vol.49
, pp. 1986-1992
-
-
Gurulingappa, H.1
Kolarik, C.2
Hofmann-Apitius, M.3
Fluck, J.4
-
3
-
-
84859732713
-
Predicting anatomical therapeutic chemical (ATC) classification of drugs by integrating chemical-chemical interactions and similarities
-
Chen, L.; Zeng, W. M.; Cai, Y. D.; Feng, K. Y.; Chou, K. C. Predicting anatomical therapeutic chemical (ATC) classification of drugs by integrating chemical-chemical interactions and similarities PLoS ONE 2012, 7, e35254
-
(2012)
PLoS ONE
, vol.7
, pp. 35254
-
-
Chen, L.1
Zeng, W.M.2
Cai, Y.D.3
Feng, K.Y.4
Chou, K.C.5
-
4
-
-
34547140875
-
The human disease network
-
Goh, K. I.; Cusick, M. E.; Valle, D.; Childs, B.; Vidal, M.; Barabasi, A. L. The human disease network Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 8685-8690
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 8685-8690
-
-
Goh, K.I.1
Cusick, M.E.2
Valle, D.3
Childs, B.4
Vidal, M.5
Barabasi, A.L.6
-
5
-
-
77649222972
-
Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets
-
Suthram, S.; Dudley, J. T.; Chiang, A. P.; Chen, R.; Hastie, T. J.; Butte, A. J. Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets PLoS Comput. Biol. 2010, 6, e1000662
-
(2010)
PLoS Comput. Biol.
, vol.6
, pp. 1000662
-
-
Suthram, S.1
Dudley, J.T.2
Chiang, A.P.3
Chen, R.4
Hastie, T.J.5
Butte, A.J.6
-
6
-
-
84864231551
-
INDI: A computational framework for inferring drug interactions and their associated recommendations
-
Gottlieb, A.; Stein, G. Y.; Oron, Y.; Ruppin, E.; Sharan, R. INDI: a computational framework for inferring drug interactions and their associated recommendations Mol. Syst. Biol. 2012, 8, 592
-
(2012)
Mol. Syst. Biol.
, vol.8
, pp. 592
-
-
Gottlieb, A.1
Stein, G.Y.2
Oron, Y.3
Ruppin, E.4
Sharan, R.5
-
7
-
-
70449634957
-
Predicting new molecular targets for known drugs
-
Keiser, M. J.; Setola, V.; Irwin, J. J.; Laggner, C.; Abbas, A. I.; Hufeisen, S. J.; Jensen, N. H.; Kuijer, M. B.; Matos, R. C.; Tran, T. B.; Whaley, R.; Glennon, R. A.; Hert, J.; Thomas, K. L.; Edwards, D. D.; Shoichet, B. K.; Roth, B. L. Predicting new molecular targets for known drugs Nature 2009, 462, 175-181
-
(2009)
Nature
, vol.462
, pp. 175-181
-
-
Keiser, M.J.1
Setola, V.2
Irwin, J.J.3
Laggner, C.4
Abbas, A.I.5
Hufeisen, S.J.6
Jensen, N.H.7
Kuijer, M.B.8
Matos, R.C.9
Tran, T.B.10
Whaley, R.11
Glennon, R.A.12
Hert, J.13
Thomas, K.L.14
Edwards, D.D.15
Shoichet, B.K.16
Roth, B.L.17
-
8
-
-
33846876695
-
Relating protein pharmacology by ligand chemistry
-
Keiser, M. J.; Roth, B. L.; Armbruster, B. N.; Ernsberger, P.; Irwin, J. J.; Shoichet, B. K. Relating protein pharmacology by ligand chemistry Nat. Biotechnol. 2007, 25, 197-206
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 197-206
-
-
Keiser, M.J.1
Roth, B.L.2
Armbruster, B.N.3
Ernsberger, P.4
Irwin, J.J.5
Shoichet, B.K.6
-
9
-
-
78651287426
-
DrugBank 3.0: A comprehensive resource for 'omics' research on drugs
-
Knox, C.; Law, V.; Jewison, T.; Liu, P.; Ly, S.; Frolkis, A.; Pon, A.; Banco, K.; Mak, C.; Neveu, V.; Djoumbou, Y.; Eisner, R.; Guo, A.; Wishart, D. DrugBank 3.0: a comprehensive resource for 'omics' research on drugs Nucleic Acids Res. 2011, 39, D1035-1041
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 1035-1041
-
-
Knox, C.1
Law, V.2
Jewison, T.3
Liu, P.4
Ly, S.5
Frolkis, A.6
Pon, A.7
Banco, K.8
Mak, C.9
Neveu, V.10
Djoumbou, Y.11
Eisner, R.12
Guo, A.13
Wishart, D.14
-
10
-
-
79953005609
-
PaDEL-descriptor: An open source software to calculate molecular descriptors and fingerprints
-
Yap, C. W. PaDEL-descriptor: an open source software to calculate molecular descriptors and fingerprints J. Comput. Chem. 2011, 32, 1466-1474
-
(2011)
J. Comput. Chem.
, vol.32
, pp. 1466-1474
-
-
Yap, C.W.1
-
11
-
-
79551587720
-
Cytoscape 2.8: New features for data integration and network visualization
-
Smoot, M. E.; Ono, K.; Ruscheinski, J.; Wang, P. L.; Ideker, T. Cytoscape 2.8: new features for data integration and network visualization Bioinformatics 2011, 27, 431-432
-
(2011)
Bioinformatics
, vol.27
, pp. 431-432
-
-
Smoot, M.E.1
Ono, K.2
Ruscheinski, J.3
Wang, P.L.4
Ideker, T.5
-
12
-
-
84883215373
-
-
DailyMed.
-
DailyMed: http://dailymed.nlm.nih.gov/.
-
-
-
-
13
-
-
0020565425
-
Metipranolol - A new beta-blocker
-
Kruse, W. [Metipranolol-a new beta-blocker] Klin. Monbl. Augenheilkd. 1983, 182, 582-584
-
(1983)
Klin. Monbl. Augenheilkd.
, vol.182
, pp. 582-584
-
-
Kruse, W.1
-
14
-
-
84924495693
-
Treatment of central serous chorioretinopathy with beta-blocker metipranolol
-
doi: 10.5507/bp.2013.015.
-
Chrapek, O.;; Jirkova, B.;; Kandrnal, V.;; Rehak, J.; Sin, M. Treatment of central serous chorioretinopathy with beta-blocker metipranolol. Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub., 2013, doi: 10.5507/bp.2013.015.
-
(2013)
Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub.
-
-
Chrapek, O.1
Jirkova, B.2
Kandrnal, V.3
Rehak, J.4
Sin, M.5
-
15
-
-
0024560657
-
A four-year study of efficacy and safety in glaucoma treatment
-
Levobunolol.
-
Levobunolol. A four-year study of efficacy and safety in glaucoma treatment. Ophthalmology 1989, 96, 642-645.
-
(1989)
Ophthalmology
, vol.96
, pp. 642-645
-
-
-
16
-
-
79958754253
-
PREDICT: A method for inferring novel drug indications with application to personalized medicine
-
Gottlieb, A.; Stein, G. Y.; Ruppin, E.; Sharan, R. PREDICT: a method for inferring novel drug indications with application to personalized medicine Mol. Syst. Biol. 2011, 7, 496
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 496
-
-
Gottlieb, A.1
Stein, G.Y.2
Ruppin, E.3
Sharan, R.4
-
17
-
-
47249146126
-
Drug target identification using side-effect similarity
-
Campillos, M.; Kuhn, M.; Gavin, A. C.; Jensen, L. J.; Bork, P. Drug target identification using side-effect similarity Science 2008, 321, 263-266
-
(2008)
Science
, vol.321
, pp. 263-266
-
-
Campillos, M.1
Kuhn, M.2
Gavin, A.C.3
Jensen, L.J.4
Bork, P.5
-
18
-
-
33749335282
-
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
-
Lamb, J.; Crawford, E. D.; Peck, D.; Modell, J. W.; Blat, I. C.; Wrobel, M. J.; Lerner, J.; Brunet, J.-P.; Subramanian, A.; Ross, K. N.; Reich, M.; Hieronymus, H.; Wei, G.; Armstrong, S. A.; Haggarty, S. J.; Clemons, P. A.; Wei, R.; Carr, S. A.; Lander, E. S.; Golub, T. R. The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease Science 2006, 313, 1929-1935
-
(2006)
Science
, vol.313
, pp. 1929-1935
-
-
Lamb, J.1
Crawford, E.D.2
Peck, D.3
Modell, J.W.4
Blat, I.C.5
Wrobel, M.J.6
Lerner, J.7
Brunet, J.-P.8
Subramanian, A.9
Ross, K.N.10
Reich, M.11
Hieronymus, H.12
Wei, G.13
Armstrong, S.A.14
Haggarty, S.J.15
Clemons, P.A.16
Wei, R.17
Carr, S.A.18
Lander, E.S.19
Golub, T.R.20
more..
-
19
-
-
84867338003
-
Discovery and preclinical validation of drug indications using compendia of public gene expression data
-
Sirota, M.; Dudley, J. T.; Kim, J.; Chiang, A. P.; Morgan, A. A.; Sweet-Cordero, A.; Sage, J.; Butte, A. J. Discovery and preclinical validation of drug indications using compendia of public gene expression data Sci. Transl. Med. 2011, 3, 96ra77
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Sirota, M.1
Dudley, J.T.2
Kim, J.3
Chiang, A.P.4
Morgan, A.A.5
Sweet-Cordero, A.6
Sage, J.7
Butte, A.J.8
-
20
-
-
54249155522
-
Network pharmacology: The next paradigm in drug discovery
-
Hopkins, A. L. Network pharmacology: the next paradigm in drug discovery Nat. Chem. Biol. 2008, 4, 682-690
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 682-690
-
-
Hopkins, A.L.1
-
21
-
-
84883252617
-
CHD@ZJU: A knowledgebase providing network-based research platform on coronary heart disease
-
doi: 10.1093/database/bat047.
-
Wu, L.; Li, X.; Yang, J.; Liu, Y.; Fan, X.; Cheng, Y. CHD@ZJU: a knowledgebase providing network-based research platform on coronary heart disease. Database (Oxford), 2013, doi: 10.1093/database/bat047.
-
(2013)
Database (Oxford)
-
-
Wu, L.1
Li, X.2
Yang, J.3
Liu, Y.4
Fan, X.5
Cheng, Y.6
-
22
-
-
84878732151
-
A network pharmacology approach to evaluating the efficacy of Chinese medicine using genome-wide transcriptional expression data
-
Wu, L.; Wang, Y.; Nie, J.; Fan, X.; Cheng, Y. A network pharmacology approach to evaluating the efficacy of Chinese medicine using genome-wide transcriptional expression data Evid. Based Complement. Alternat. Med. 2013, 2013, 915343
-
(2013)
Evid. Based Complement. Alternat. Med.
, vol.2013
, pp. 915343
-
-
Wu, L.1
Wang, Y.2
Nie, J.3
Fan, X.4
Cheng, Y.5
-
23
-
-
77952839641
-
Advances in 2D fingerprint similarity searching
-
Geppert, H.; Bajorath, J. Advances in 2D fingerprint similarity searching Expert Opin. Drug Discovery 2010, 5, 529-542
-
(2010)
Expert Opin. Drug Discovery
, vol.5
, pp. 529-542
-
-
Geppert, H.1
Bajorath, J.2
|