메뉴 건너뛰기




Volumn 2, Issue 3, 2013, Pages 142-152

Peripheral activation of the Y2-receptor promotes secretion of GLP-1 and improves glucose tolerance

Author keywords

GLP 1; Glucose homeostasis; PYY; Y2 receptor

Indexed keywords

EXENDIN[9-39]; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; GLUCOSE; N [2 [1,2 DIHYDRO 3,5(4H) DIOXO 1,2 DIPHENYL 1,2,4 TRIAZOL 4 YL]ETHYL] N2 [[1 [2 [4 [5,11 DIHYDRO 6(6H) OXODIBENZ[B,E]AZEPIN 11 YL] 1 PIPERAZINYL] 2 OXOETHYL]CYCLOPENTYL]ACETYL]ARGININAMIDE; NEUROPEPTIDE Y; NEUROPEPTIDE Y [28 LEUCINE 31 PROLINE]; PEPTIDE YY [3-36]; UNCLASSIFIED DRUG;

EID: 84883222261     PISSN: 22128778     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmet.2013.03.001     Document Type: Article
Times cited : (51)

References (46)
  • 1
    • 33845998516 scopus 로고    scopus 로고
    • The role of gut hormones in glucose homeostasis
    • Drucker D.J. The role of gut hormones in glucose homeostasis. Journal of Clinical Investigation 2007, 117:24-32.
    • (2007) Journal of Clinical Investigation , vol.117 , pp. 24-32
    • Drucker, D.J.1
  • 2
    • 84866705627 scopus 로고    scopus 로고
    • From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior
    • Williams K.W., Elmquist J.K. From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior. Nature Neuroscience 2012, 15:1350-1355.
    • (2012) Nature Neuroscience , vol.15 , pp. 1350-1355
    • Williams, K.W.1    Elmquist, J.K.2
  • 3
    • 84860702051 scopus 로고    scopus 로고
    • Shedding pounds after going under the knife: metabolic insights from cutting the gut
    • Chandarana K., Batterham R.L. Shedding pounds after going under the knife: metabolic insights from cutting the gut. Nature Medicine 2012, 18:668-669.
    • (2012) Nature Medicine , vol.18 , pp. 668-669
    • Chandarana, K.1    Batterham, R.L.2
  • 4
    • 80054844912 scopus 로고    scopus 로고
    • Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium
    • Tam C.S., Berthoud H.R., Bueter M., Chakravarthy M.V., Geliebter A., Hajnal A., et al. Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium. Obesity Reviews 2011, 12:984-994.
    • (2011) Obesity Reviews , vol.12 , pp. 984-994
    • Tam, C.S.1    Berthoud, H.R.2    Bueter, M.3    Chakravarthy, M.V.4    Geliebter, A.5    Hajnal, A.6
  • 5
    • 80052135804 scopus 로고    scopus 로고
    • Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats
    • Chambers A.P., Jessen L., Ryan K.K., Sisley S., Wilson-Perez H.E., Stefater M.A., et al. Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. Gastroenterology 2011, 141:950-958.
    • (2011) Gastroenterology , vol.141 , pp. 950-958
    • Chambers, A.P.1    Jessen, L.2    Ryan, K.K.3    Sisley, S.4    Wilson-Perez, H.E.5    Stefater, M.A.6
  • 6
    • 0033303516 scopus 로고    scopus 로고
    • Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine
    • Hansen L., Deacon C.F., Orskov C., Holst J.J. Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. Endocrinology 1999, 140:5356-5363.
    • (1999) Endocrinology , vol.140 , pp. 5356-5363
    • Hansen, L.1    Deacon, C.F.2    Orskov, C.3    Holst, J.J.4
  • 7
    • 74749108848 scopus 로고    scopus 로고
    • Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes
    • Asmar M., Hojberg P.V., Deacon C.F., Hare K., Holst J.J., Madsbad S. Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes. Regulatory Peptides 2010, 160:175-180.
    • (2010) Regulatory Peptides , vol.160 , pp. 175-180
    • Asmar, M.1    Hojberg, P.V.2    Deacon, C.F.3    Hare, K.4    Holst, J.J.5    Madsbad, S.6
  • 8
    • 0027494070 scopus 로고
    • Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV
    • Mentlein R., Dahms P., Grandt D., Kruger R. Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV. Regulatory Peptides 1993, 49:133-144.
    • (1993) Regulatory Peptides , vol.49 , pp. 133-144
    • Mentlein, R.1    Dahms, P.2    Grandt, D.3    Kruger, R.4
  • 12
    • 33646517058 scopus 로고    scopus 로고
    • Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity
    • Boey D., Lin S., Karl T., Baldock P., Lee N., Enriquez R., et al. Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity. Diabetologia 2006, 49:1360-1370.
    • (2006) Diabetologia , vol.49 , pp. 1360-1370
    • Boey, D.1    Lin, S.2    Karl, T.3    Baldock, P.4    Lee, N.5    Enriquez, R.6
  • 14
    • 18044365777 scopus 로고    scopus 로고
    • Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake
    • Abbott C.R., Small C.J., Kennedy A.R., Neary N.M., Sajedi A., Ghatei M.A., et al. Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake. Brain Research 2005, 1043:139-144.
    • (2005) Brain Research , vol.1043 , pp. 139-144
    • Abbott, C.R.1    Small, C.J.2    Kennedy, A.R.3    Neary, N.M.4    Sajedi, A.5    Ghatei, M.A.6
  • 15
    • 33846612846 scopus 로고    scopus 로고
    • The role of peptide YY in regulating glucose homeostasis
    • Boey D., Sainsbury A., Herzog H. The role of peptide YY in regulating glucose homeostasis. Peptides 2007, 28:390-395.
    • (2007) Peptides , vol.28 , pp. 390-395
    • Boey, D.1    Sainsbury, A.2    Herzog, H.3
  • 16
    • 0024339140 scopus 로고
    • Peptide YY: intrapancreatic localization and effects on insulin and glucagon secretion in the mouse
    • Bottcher G., Ahren B., Lundquist I., Sundler F. Peptide YY: intrapancreatic localization and effects on insulin and glucagon secretion in the mouse. Pancreas 1989, 4:282-288.
    • (1989) Pancreas , vol.4 , pp. 282-288
    • Bottcher, G.1    Ahren, B.2    Lundquist, I.3    Sundler, F.4
  • 18
    • 35548958265 scopus 로고    scopus 로고
    • A novel long-acting selective neuropeptide Y2 receptor polyethylene glycol-conjugated peptide agonist reduces food intake and body weight and improves glucose metabolism in rodents
    • Ortiz A.A., Milardo L.F., DeCarr L.B., Buckholz T.M., Mays M.R., Claus T.H., et al. A novel long-acting selective neuropeptide Y2 receptor polyethylene glycol-conjugated peptide agonist reduces food intake and body weight and improves glucose metabolism in rodents. Journal of Pharmacology and Experimental Therapeutics 2007, 323:692-700.
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.323 , pp. 692-700
    • Ortiz, A.A.1    Milardo, L.F.2    DeCarr, L.B.3    Buckholz, T.M.4    Mays, M.R.5    Claus, T.H.6
  • 24
    • 0037423057 scopus 로고    scopus 로고
    • Enhanced effects of central angiotensin II on cardiovascular and drinking responses in inbred polydipsic (STR/N) mice
    • Chu C.P., Kato K., Kunitake T., Watanabe S., Qiu D.L., Ueta Y., et al. Enhanced effects of central angiotensin II on cardiovascular and drinking responses in inbred polydipsic (STR/N) mice. Brain Research 2003, 962:129-134.
    • (2003) Brain Research , vol.962 , pp. 129-134
    • Chu, C.P.1    Kato, K.2    Kunitake, T.3    Watanabe, S.4    Qiu, D.L.5    Ueta, Y.6
  • 25
    • 68049137606 scopus 로고    scopus 로고
    • Deletion of PKC{varepsilon} selectively enhances the amplifying pathways of glucose-stimulated insulin secretion via increased lipolysis in mouse {beta}-cells
    • Cantley J., Burchfield J.G., Pearson G.L., Schmitz-Peiffer C., Leitges M., Biden T.J. Deletion of PKC{varepsilon} selectively enhances the amplifying pathways of glucose-stimulated insulin secretion via increased lipolysis in mouse {beta}-cells. Diabetes 2009.
    • (2009) Diabetes
    • Cantley, J.1    Burchfield, J.G.2    Pearson, G.L.3    Schmitz-Peiffer, C.4    Leitges, M.5    Biden, T.J.6
  • 26
    • 79952385410 scopus 로고    scopus 로고
    • Diet and gastrointestinal bypass-induced weight loss: the roles of ghrelin and peptide YY
    • Chandarana K., Gelegen C., Karra E., Choudhury A.I., Drew M.E., Fauveau V., et al. Diet and gastrointestinal bypass-induced weight loss: the roles of ghrelin and peptide YY. Diabetes 2011, 60:810-818.
    • (2011) Diabetes , vol.60 , pp. 810-818
    • Chandarana, K.1    Gelegen, C.2    Karra, E.3    Choudhury, A.I.4    Drew, M.E.5    Fauveau, V.6
  • 27
    • 50049119700 scopus 로고    scopus 로고
    • Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice
    • Troy S., Soty M., Ribeiro L., Laval L., Migrenne S., Fioramonti X., et al. Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metabolism 2008, 8:201-211.
    • (2008) Cell Metabolism , vol.8 , pp. 201-211
    • Troy, S.1    Soty, M.2    Ribeiro, L.3    Laval, L.4    Migrenne, S.5    Fioramonti, X.6
  • 29
    • 0026670873 scopus 로고
    • Evidence for a direct inhibitory effect of PYY on insulin secretion in rats
    • Bertrand G., Gross R., Roye M., Ahren B., Ribes G. Evidence for a direct inhibitory effect of PYY on insulin secretion in rats. Pancreas 1992, 7:595-600.
    • (1992) Pancreas , vol.7 , pp. 595-600
    • Bertrand, G.1    Gross, R.2    Roye, M.3    Ahren, B.4    Ribes, G.5
  • 30
    • 0029948677 scopus 로고    scopus 로고
    • A role for islet peptide YY in the regulation of insulin secretion
    • Karlsson S., Ahren B. A role for islet peptide YY in the regulation of insulin secretion. Acta Physiologica Scandinavica 1996, 157:305-306.
    • (1996) Acta Physiologica Scandinavica , vol.157 , pp. 305-306
    • Karlsson, S.1    Ahren, B.2
  • 31
    • 0035089197 scopus 로고    scopus 로고
    • Increased insulin concentrations and glucose storage in neuropeptide Y Y1 receptor-deficient mice
    • Burcelin R., Brunner H., Seydoux J., Thorensa B., Pedrazzini T. Increased insulin concentrations and glucose storage in neuropeptide Y Y1 receptor-deficient mice. Peptides 2001, 22:421-427.
    • (2001) Peptides , vol.22 , pp. 421-427
    • Burcelin, R.1    Brunner, H.2    Seydoux, J.3    Thorensa, B.4    Pedrazzini, T.5
  • 32
    • 0028108628 scopus 로고
    • Mechanisms underlying the insulinostatic effect of peptide YY in mouse pancreatic islets
    • Nieuwenhuizen A.G., Karlsson S., Fridolf T., Ahren B. Mechanisms underlying the insulinostatic effect of peptide YY in mouse pancreatic islets. Diabetologia 1994, 37:871-878.
    • (1994) Diabetologia , vol.37 , pp. 871-878
    • Nieuwenhuizen, A.G.1    Karlsson, S.2    Fridolf, T.3    Ahren, B.4
  • 33
    • 36949012499 scopus 로고    scopus 로고
    • Distribution of peripherally injected peptide YY ([125I] PYY (3-36)) and pancreatic polypeptide ([125I] hPP) in the CNS: enrichment in the area postrema
    • Dumont Y., Moyse E., Fournier A., Quirion R. Distribution of peripherally injected peptide YY ([125I] PYY (3-36)) and pancreatic polypeptide ([125I] hPP) in the CNS: enrichment in the area postrema. Journal of Molecular Neuroscience 2007, 33:294-304.
    • (2007) Journal of Molecular Neuroscience , vol.33 , pp. 294-304
    • Dumont, Y.1    Moyse, E.2    Fournier, A.3    Quirion, R.4
  • 34
    • 0038411365 scopus 로고    scopus 로고
    • The level of NPY receptor mRNA expression in diet-induced obese and resistant mice
    • Huang X.F., Han M., Storlien L.H. The level of NPY receptor mRNA expression in diet-induced obese and resistant mice. Brain Research Molecular Brain Research 2003, 115:21-28.
    • (2003) Brain Research Molecular Brain Research , vol.115 , pp. 21-28
    • Huang, X.F.1    Han, M.2    Storlien, L.H.3
  • 35
    • 34748881759 scopus 로고    scopus 로고
    • Decreased plasma peptide YY accompanied by elevated peptide YY and Y2 receptor binding densities in the medulla oblongata of diet-induced obese mice
    • Rahardjo G.L., Huang X.F., Tan Y.Y., Deng C. Decreased plasma peptide YY accompanied by elevated peptide YY and Y2 receptor binding densities in the medulla oblongata of diet-induced obese mice. Endocrinology 2007, 148:4704-4710.
    • (2007) Endocrinology , vol.148 , pp. 4704-4710
    • Rahardjo, G.L.1    Huang, X.F.2    Tan, Y.Y.3    Deng, C.4
  • 36
    • 80052719514 scopus 로고    scopus 로고
    • Diabetes remission after bariatric surgery: is it just the incretins?
    • Laferrere B. Diabetes remission after bariatric surgery: is it just the incretins?. International Journal of Obesity (London) 2011, 35(Suppl 3):S22-S25.
    • (2011) International Journal of Obesity (London) , vol.35 , Issue.SUPPL 3
    • Laferrere, B.1
  • 37
    • 79959968543 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: understanding weight loss and improvements in type 2 diabetes after bariatric surgery
    • Scott W.R., Batterham R.L. Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: understanding weight loss and improvements in type 2 diabetes after bariatric surgery. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2011, 301:R15-R27.
    • (2011) American Journal of Physiology-Regulatory, Integrative and Comparative Physiology , vol.301
    • Scott, W.R.1    Batterham, R.L.2
  • 39
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • Holst J.J. The physiology of glucagon-like peptide 1. Physiological Reviews 2007, 87:1409-1439.
    • (2007) Physiological Reviews , vol.87 , pp. 1409-1439
    • Holst, J.J.1
  • 40
    • 58149295120 scopus 로고    scopus 로고
    • Nutritional regulation of glucagon-like peptide-1 secretion
    • Tolhurst G., Reimann F., Gribble F.M. Nutritional regulation of glucagon-like peptide-1 secretion. Journal of Physiology 2009, 587:27-32.
    • (2009) Journal of Physiology , vol.587 , pp. 27-32
    • Tolhurst, G.1    Reimann, F.2    Gribble, F.M.3
  • 41
    • 0032499598 scopus 로고    scopus 로고
    • Identification and distribution of mRNA encoding the Y1, Y2, Y4, and Y5 receptors for peptides of the PP-fold family in the rat intestine and colon
    • Goumain M., Voisin T., Lorinet A.M., Laburthe M. Identification and distribution of mRNA encoding the Y1, Y2, Y4, and Y5 receptors for peptides of the PP-fold family in the rat intestine and colon. Biochemical and Biophysical Research Communications 1998, 247:52-56.
    • (1998) Biochemical and Biophysical Research Communications , vol.247 , pp. 52-56
    • Goumain, M.1    Voisin, T.2    Lorinet, A.M.3    Laburthe, M.4
  • 45
    • 67649636449 scopus 로고    scopus 로고
    • Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
    • Ruttimann E.B., Arnold M., Hillebrand J.J., Geary N., Langhans W. Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 2009, 150:1174-1181.
    • (2009) Endocrinology , vol.150 , pp. 1174-1181
    • Ruttimann, E.B.1    Arnold, M.2    Hillebrand, J.J.3    Geary, N.4    Langhans, W.5
  • 46
    • 84871700574 scopus 로고    scopus 로고
    • Possible mechanisms of circulating PYY-induced satiation in male rats
    • Stadlbauer U., Arnold M., Weber E., Langhans W. Possible mechanisms of circulating PYY-induced satiation in male rats. Endocrinology 2013, 154:193-204.
    • (2013) Endocrinology , vol.154 , pp. 193-204
    • Stadlbauer, U.1    Arnold, M.2    Weber, E.3    Langhans, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.