Therapeutic hypothermia cardioprotection via Akt- and nitric oxide-mediated attenuation of mitochondrial oxidants

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 6, 2010, Pages

  Shao, Zuo Hui ^a   Sharp, Willard W ^a   Wojcik, Kimberly R ^a   Li, Chang Qing ^a   Han, Mei ^a   Chang, Wei Tien ^b   Ramachandran, Srinivasan ^a   Li, Jing ^a   Hamann, Kimm J ^a   Vanden Hoek, Terry L ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Cardiomyocyte; Ischemia reperfusion; Reactive oxygen species

Indexed keywords

HEAT SHOCK PROTEIN 27; LACTATE DEHYDROGENASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROPIDIUM IODIDE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; INDUCED HYPOTHERMIA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HSP27 HEAT-SHOCK PROTEINS; HYPOTHERMIA, INDUCED; MICE; MICE, INBRED C57BL; MITOCHONDRIA, HEART; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NITRIC OXIDE; OXIDANTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; TIME FACTORS;

EID: 77952630826     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00994.2009     Document Type: Article

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