Isoliquiritigenin, a flavonoid from licorice, plays a dual role in regulating gastrointestinal motility in vitro and in vivo

Phytotherapy Research

Volumn 23, Issue 4, 2009, Pages 498-506

  Chen, Gang ^a   Zhu, Lingxin ^a   Liu, Yang ^a   Zhou, Qian ^a   Chen, Hao ^a   Yang, Jing ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Calcium antagonist; Glycyrrhiza glabra; Isoliquiritigenin; Muscarinic receptors; Spasmogenic; Spasmolytic

Indexed keywords

4 AMINOPYRIDINE; ATROPINE; CALCIUM ION; CHARCOAL; CLOTRIMAZOLE; GLIBENCLAMIDE; INDOMETACIN; ISOLIQUIRITIGENIN; METHYLENE BLUE; N(G) NITROARGININE METHYL ESTER; POTASSIUM ION; TETRYLAMMONIUM CHLORIDE; CHALCONE DERIVATIVE; CHOLINERGIC RECEPTOR BLOCKING AGENT;

ANIMAL TISSUE; ARTICLE; CALCIUM ANTAGONISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG DOSE INCREASE; DRUG EFFECT; DRUG MEGADOSE; DRUG SYNTHESIS; GASTROINTESTINAL MOTILITY; GLYCYRRHIZA GLABRA; GUINEA PIG; ILEUM; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; INTESTINE CONTRACTION; ISOLATION PROCEDURE; JEJUNUM; LOW DRUG DOSE; MOUSE; NONHUMAN; RABBIT; RAT; STOMACH FUNDUS; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; FEMALE; GLYCYRRHIZA; MALE; PLANT ROOT; SPRAGUE DAWLEY RAT; TOXICITY TESTING; WISTAR RAT;

CAVIA; GLYCYRRHIZA; GLYCYRRHIZA GLABRA; ORYCTOLAGUS CUNICULUS; RATTUS;

ANIMALS; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTRIC FUNDUS; GASTROINTESTINAL MOTILITY; GLYCYRRHIZA; GUINEA PIGS; ILEUM; JEJUNUM; MALE; MICE; MICE, INBRED BALB C; PARASYMPATHOLYTICS; PLANT ROOTS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; TOXICITY TESTS;

EID: 64549156951     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2660     Document Type: Article

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