Protein-tyrosine phosphatase 1B antagonized signaling by insulin-like growth factor-1 receptor and kinase BRK/PTK6 in ovarian cancer cells

Journal of Biological Chemistry

Volumn 288, Issue 34, 2013, Pages 24923-24934

  Fan, Gaofeng ^a   Lin, Guang ^a   Lucito, Robert ^a,b   Tonks, Nicholas K ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROGENEOUS DISEASE; INSULIN-LIKE GROWTH FACTOR-1 RECEPTORS; MOLECULAR INHIBITORS; NEGATIVE REGULATORS; OVARIAN CANCER CELLS; PROTEIN PHOSPHATASE; PROTEIN-TYROSINE KINASE; PROTEIN-TYROSINE PHOSPHATASE 1B;

AMINO ACIDS; CELL CULTURE; CELL DEATH; DISEASES; INSULIN; PHOSPHATASES; PIGMENTS; PROTEINS; RESTORATION;

SIGNALING;

PROTEIN BCL 2; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE 6; PROTEIN TYROSINE PHOSPHATASE 1B; SOMATOMEDIN C RECEPTOR; TRODUSQUEMINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; OVARY CANCER; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TUMOR INVASION;

BRK; CELL DEATH; DEPHOSPHORYLATION; IGF-1R; OVARIAN CANCER; PHOSPHORYLATION; PTP1B; TYROSINE-PROTEIN KINASE (TYROSINE KINASE); TYROSINE-PROTEIN PHOSPHATASE (TYROSINE PHOSPHATASE);

BCL-ASSOCIATED DEATH PROTEIN; CELL LINE, TUMOR; CHOLESTANES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; PROTEIN-TYROSINE KINASES; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; SPERMINE;

EID: 84883189052     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.482737     Document Type: Article

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