메뉴 건너뛰기




Volumn 3, Issue 1, 2013, Pages 76-84

Molecular imaging of chemokine receptor CXCR4

Author keywords

Cancer; CXCR4; Diagnostics; Molecular imaging

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 1,4,7 TRIAZACYCLONONANE 1,4,7 TRIACETIC ACID; ACTZ 14011; AMD 3645; CARBOXYFLUORESCEIN; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; CHEMOKINE RECEPTOR CXCR7; COPPER 64; FC 131; FLUORINE 18; GALLIUM 68; INDIUM 111; IODINE 125; MSX 122; PLERIXAFOR; RADIOPHARMACEUTICAL AGENT; STROMAL CELL DERIVED FACTOR 1; T 140; TECHNETIUM 99M; TY 14003; UNCLASSIFIED DRUG;

EID: 84883187912     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.4835     Document Type: Review
Times cited : (78)

References (55)
  • 1
    • 0033646431 scopus 로고    scopus 로고
    • CXCR4: chemokine receptor extraordinaire
    • Murdoch C. CXCR4: chemokine receptor extraordinaire. Immunol Rev. 2000; 177: 175-84.
    • (2000) Immunol Rev. , vol.177 , pp. 175-184
    • Murdoch, C.1
  • 3
    • 0038206771 scopus 로고    scopus 로고
    • The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological biological axis in non-small cell lung cancer metastases
    • Phillips RJ, Burdick MD, Lutz M, Belperio JA, Keane MP, Strieter RM. The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological biological axis in non-small cell lung cancer metastases. Am J Respir Crit Care Med. 2003; 167: 1676-86.
    • (2003) Am J Respir Crit Care Med. , vol.167 , pp. 1676-1686
    • Phillips, R.J.1    Burdick, M.D.2    Lutz, M.3    Belperio, J.A.4    Keane, M.P.5    Strieter, R.M.6
  • 4
    • 2342591450 scopus 로고    scopus 로고
    • The significance of cancer cell expression of the chemokine receptor CXCR4
    • Balkwill F. The significance of cancer cell expression of the chemokine receptor CXCR4. Semin Cancer Biol. 2004; 14: 171-9.
    • (2004) Semin Cancer Biol. , vol.14 , pp. 171-179
    • Balkwill, F.1
  • 5
    • 0033524834 scopus 로고    scopus 로고
    • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
    • Peled A, Petit I, Kollet O, Magid M, Ponomaryov T, Byk T, et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science. 1999; 283: 845-8.
    • (1999) Science. , vol.283 , pp. 845-848
    • Peled, A.1    Petit, I.2    Kollet, O.3    Magid, M.4    Ponomaryov, T.5    Byk, T.6
  • 9
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature. 2001; 410: 50-6.
    • (2001) Nature. , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3    Ge, N.4    Catron, D.5    Buchanan, M.E.6
  • 10
    • 33845312983 scopus 로고    scopus 로고
    • CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas
    • Redjal N, Chan JA, Segal RA, Kung AL. CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas. Clin Cancer Res. 2006; 12: 6765-71.
    • (2006) Clin Cancer Res. , vol.12 , pp. 6765-6771
    • Redjal, N.1    Chan, J.A.2    Segal, R.A.3    Kung, A.L.4
  • 13
    • 66149150580 scopus 로고    scopus 로고
    • CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
    • Azab AK, Runnels JM, Pitsillides C, Moreau AS, Azab F, Leleu X, et al. CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood. 2009; 113: 4341-51.
    • (2009) Blood. , vol.113 , pp. 4341-4351
    • Azab, A.K.1    Runnels, J.M.2    Pitsillides, C.3    Moreau, A.S.4    Azab, F.5    Leleu, X.6
  • 14
    • 66549113998 scopus 로고    scopus 로고
    • Mantle cell lymphoma cells express high levels of CXCR4, CXCR5, and VLA-4 (CD49d): importance for interactions with the stromal microenvironment and specific targeting
    • Kurtova AV, Tamayo AT, Ford RJ, Burger JA. Mantle cell lymphoma cells express high levels of CXCR4, CXCR5, and VLA-4 (CD49d): importance for interactions with the stromal microenvironment and specific targeting. Blood. 2009; 113: 4604-13.
    • (2009) Blood. , vol.113 , pp. 4604-4613
    • Kurtova, A.V.1    Tamayo, A.T.2    Ford, R.J.3    Burger, J.A.4
  • 15
    • 34547634399 scopus 로고    scopus 로고
    • CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models
    • Yoon Y, Liang Z, Zhang X, Choe M, Zhu A, Cho HT, et al. CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models. Cancer Res. 2007; 67: 7518-24.
    • (2007) Cancer Res. , vol.67 , pp. 7518-7524
    • Yoon, Y.1    Liang, Z.2    Zhang, X.3    Choe, M.4    Zhu, A.5    Cho, H.T.6
  • 16
    • 45849087256 scopus 로고    scopus 로고
    • Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro
    • Li JK, Yu L, Shen Y, Zhou LS, Wang YC, Zhang JH. Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro. World J Gastroenterol. 2008; 14: 2308-13.
    • (2008) World J Gastroenterol. , vol.14 , pp. 2308-2313
    • Li, J.K.1    Yu, L.2    Shen, Y.3    Zhou, L.S.4    Wang, Y.C.5    Zhang, J.H.6
  • 17
    • 64549163342 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer
    • Lee HJ, Kim SW, Kim HY, Li S, Yun HJ, Song KS, et al. Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer. Int J Oncol. 2009; 34: 473-80.
    • (2009) Int J Oncol. , vol.34 , pp. 473-480
    • Lee, H.J.1    Kim, S.W.2    Kim, H.Y.3    Li, S.4    Yun, H.J.5    Song, K.S.6
  • 18
    • 62449204461 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 expression is correlated with VEGF expression and poor survival in soft-tissue sarcoma
    • Oda Y, Tateishi N, Matono H, Matsuura S, Yamamaoto H, Tamiya S, et al. Chemokine receptor CXCR4 expression is correlated with VEGF expression and poor survival in soft-tissue sarcoma. Int J Cancer. 2009; 124: 1852-9.
    • (2009) Int J Cancer. , vol.124 , pp. 1852-1859
    • Oda, Y.1    Tateishi, N.2    Matono, H.3    Matsuura, S.4    Yamamaoto, H.5    Tamiya, S.6
  • 19
    • 41849104653 scopus 로고    scopus 로고
    • PET versus SPECT: strengths, limitations and challenges
    • Rahmim A, Zaidi H. PET versus SPECT: strengths, limitations and challenges. Nucl Med Commun. 2008; 29: 193-207.
    • (2008) Nucl Med Commun. , vol.29 , pp. 193-207
    • Rahmim, A.1    Zaidi, H.2
  • 20
    • 33646551746 scopus 로고    scopus 로고
    • Development of a 111In-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors
    • Hanaoka H, Mukai T, Tamamura H, Mori T, Ishino S, Ogawa K, et al. Development of a 111In-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors. Nucl Med Biol. 2006; 33: 489-94.
    • (2006) Nucl Med Biol. , vol.33 , pp. 489-494
    • Hanaoka, H.1    Mukai, T.2    Tamamura, H.3    Mori, T.4    Ishino, S.5    Ogawa, K.6
  • 21
    • 67650033114 scopus 로고    scopus 로고
    • Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT
    • Nimmagadda S, Pullambhatla M, Pomper MG. Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT. J Nucl Med. 2009; 50: 1124-30.
    • (2009) J Nucl Med. , vol.50 , pp. 1124-1130
    • Nimmagadda, S.1    Pullambhatla, M.2    Pomper, M.G.3
  • 22
    • 44849123786 scopus 로고    scopus 로고
    • Quantitation of CXCR4 expression in myocardial infarction using 99mTc-labeled SDF-1alpha
    • Misra P, Lebeche D, Ly H, Schwarzkopf M, Diaz G, Hajjar RJ, et al. Quantitation of CXCR4 expression in myocardial infarction using 99mTc-labeled SDF-1alpha. J Nucl Med. 2008; 49: 963-9.
    • (2008) J Nucl Med. , vol.49 , pp. 963-969
    • Misra, P.1    Lebeche, D.2    Ly, H.3    Schwarzkopf, M.4    Diaz, G.5    Hajjar, R.J.6
  • 23
    • 33746629469 scopus 로고    scopus 로고
    • Clinical molecular imaging with positron emission tomography
    • Saleem A, Charnley N, Price P. Clinical molecular imaging with positron emission tomography. Eur J Cancer. 2006; 42: 1720-7.
    • (2006) Eur J Cancer. , vol.42 , pp. 1720-1727
    • Saleem, A.1    Charnley, N.2    Price, P.3
  • 25
    • 84861481354 scopus 로고    scopus 로고
    • Positron emission tomography imaging of tumors expressing the human chemokine receptor CXCR4 in mice with the use of (6)(4)Cu-AMD3100
    • Weiss ID, Jacobson O, Kiesewetter DO, Jacobus JP, Szajek LP, Chen X, et al. Positron emission tomography imaging of tumors expressing the human chemokine receptor CXCR4 in mice with the use of (6)(4)Cu-AMD3100. Mol Imaging Biol. 2011; 14: 106-14.
    • (2011) Mol Imaging Biol. , vol.14 , pp. 106-114
    • Weiss, I.D.1    Jacobson, O.2    Kiesewetter, D.O.3    Jacobus, J.P.4    Szajek, L.P.5    Chen, X.6
  • 26
    • 77952792463 scopus 로고    scopus 로고
    • Molecular imaging of CXCR4 receptor expression in human cancer xenografts with [64Cu]AMD3100 positron emission tomography
    • Nimmagadda S, Pullambhatla M, Stone K, Green G, Bhujwalla ZM, Pomper MG. Molecular imaging of CXCR4 receptor expression in human cancer xenografts with [64Cu]AMD3100 positron emission tomography. Cancer Res. 2010; 70: 3935-44.
    • (2010) Cancer Res. , vol.70 , pp. 3935-3944
    • Nimmagadda, S.1    Pullambhatla, M.2    Stone, K.3    Green, G.4    Bhujwalla, Z.M.5    Pomper, M.G.6
  • 27
    • 38549175201 scopus 로고    scopus 로고
    • Immunohistochemical expression of stromal cell-derived factor-1 (SDF-1) and CXCR4 ligand receptor system in hepatocellular carcinoma
    • Li W, Gomez E, Zhang Z. Immunohistochemical expression of stromal cell-derived factor-1 (SDF-1) and CXCR4 ligand receptor system in hepatocellular carcinoma. J Exp Clin Cancer Res. 2007; 26: 527-33.
    • (2007) J Exp Clin Cancer Res. , vol.26 , pp. 527-533
    • Li, W.1    Gomez, E.2    Zhang, Z.3
  • 28
    • 9644275633 scopus 로고    scopus 로고
    • Expression of stromal cell-derived factor-1 and of its receptor CXCR4 in liver regeneration from oval cells in rat
    • Mavier P, Martin N, Couchie D, Preaux AM, Laperche Y, Zafrani ES. Expression of stromal cell-derived factor-1 and of its receptor CXCR4 in liver regeneration from oval cells in rat. Am J Pathol. 2004; 165: 1969-77.
    • (2004) Am J Pathol. , vol.165 , pp. 1969-1977
    • Mavier, P.1    Martin, N.2    Couchie, D.3    Preaux, A.M.4    Laperche, Y.5    Zafrani, E.S.6
  • 29
    • 0036961904 scopus 로고    scopus 로고
    • SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats
    • Hatch HM, Zheng D, Jorgensen ML, Petersen BE. SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats. Cloning Stem Cells. 2002; 4: 339-51.
    • (2002) Cloning Stem Cells. , vol.4 , pp. 339-351
    • Hatch, H.M.1    Zheng, D.2    Jorgensen, M.L.3    Petersen, B.E.4
  • 34
    • 84857030157 scopus 로고    scopus 로고
    • Synthesis and in vitro evaluation of 68Ga-DOTA-4-FBn-TN14003, a novel tracer for the imaging of CXCR4 expression
    • Hennrich U, Seyler L, Schafer M, Bauder-Wust U, Eisenhut M, Semmler W, et al. Synthesis and in vitro evaluation of 68Ga-DOTA-4-FBn-TN14003, a novel tracer for the imaging of CXCR4 expression. Bioorg Med Chem. 2012; 20: 1502-10.
    • (2012) Bioorg Med Chem. , vol.20 , pp. 1502-1510
    • Hennrich, U.1    Seyler, L.2    Schafer, M.3    Bauder-Wust, U.4    Eisenhut, M.5    Semmler, W.6
  • 35
    • 80455162590 scopus 로고    scopus 로고
    • Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4
    • Demmer O, Dijkgraaf I, Schumacher U, Marinelli L, Cosconati S, Gourni E, et al. Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4. J Med Chem. 2011; 54: 7648-62.
    • (2011) J Med Chem. , vol.54 , pp. 7648-7662
    • Demmer, O.1    Dijkgraaf, I.2    Schumacher, U.3    Marinelli, L.4    Cosconati, S.5    Gourni, E.6
  • 38
    • 84859227686 scopus 로고    scopus 로고
    • Development of a unique small molecule modulator of CXCR4
    • Liang Z, Zhan W, Zhu A, Yoon Y, Lin S, Sasaki M, et al. Development of a unique small molecule modulator of CXCR4. PLoS One. 2012; 7: e34038.
    • (2012) PLoS One. , vol.7 , pp. 34038
    • Liang, Z.1    Zhan, W.2    Zhu, A.3    Yoon, Y.4    Lin, S.5    Sasaki, M.6
  • 39
    • 84858070141 scopus 로고    scopus 로고
    • Bioluminescence imaging: looking beyond the light
    • Keyaerts M, Caveliers V, Lahoutte T. Bioluminescence imaging: looking beyond the light. Trends Mol Med. 2012; 18: 164-72.
    • (2012) Trends Mol Med. , vol.18 , pp. 164-172
    • Keyaerts, M.1    Caveliers, V.2    Lahoutte, T.3
  • 40
    • 9444239192 scopus 로고    scopus 로고
    • Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis
    • Darash-Yahana M, Pikarsky E, Abramovitch R, Zeira E, Pal B, Karplus R, et al. Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J. 2004; 18: 1240-2.
    • (2004) FASEB J. , vol.18 , pp. 1240-1242
    • Darash-Yahana, M.1    Pikarsky, E.2    Abramovitch, R.3    Zeira, E.4    Pal, B.5    Karplus, R.6
  • 41
    • 0032786501 scopus 로고    scopus 로고
    • New reporter cell lines to study macrophage-tropic HIV envelope protein- mediated cell-cell fusion
    • Hong YL, Wu LH, Cui M, McMaster G, Hunt SW, 3rd, Chung FZ. New reporter cell lines to study macrophage-tropic HIV envelope protein- mediated cell-cell fusion. AIDS Res Hum Retroviruses. 1999; 15: 1667-72.
    • (1999) AIDS Res Hum Retroviruses. , vol.15 , pp. 1667-1672
    • Hong, Y.L.1    Wu, L.H.2    Cui, M.3    McMaster, G.4    Hunt, S.W.5    Chung, F.Z.6
  • 43
    • 70149106504 scopus 로고    scopus 로고
    • Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7
    • Luker K, Gupta M, Luker G. Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7. Biotechniques. 2009; 47: 625-32.
    • (2009) Biotechniques. , vol.47 , pp. 625-632
    • Luker, K.1    Gupta, M.2    Luker, G.3
  • 45
    • 84855546063 scopus 로고    scopus 로고
    • In vivo imaging of ligand receptor binding with Gaussia luciferase complementation
    • Luker KE, Mihalko LA, Schmidt BT, Lewin SA, Ray P, Shcherbo D, et al. In vivo imaging of ligand receptor binding with Gaussia luciferase complementation. Nat Med. 2011; 18: 172-7.
    • (2011) Nat Med. , vol.18 , pp. 172-177
    • Luker, K.E.1    Mihalko, L.A.2    Schmidt, B.T.3    Lewin, S.A.4    Ray, P.5    Shcherbo, D.6
  • 46
    • 49049108182 scopus 로고    scopus 로고
    • Imaging CXCR4 signaling with firefly luciferase complementation
    • Luker KE, Gupta M, Luker GD. Imaging CXCR4 signaling with firefly luciferase complementation. Anal Chem. 2008; 80: 5565-73.
    • (2008) Anal Chem. , vol.80 , pp. 5565-5573
    • Luker, K.E.1    Gupta, M.2    Luker, G.D.3
  • 47
    • 73249116830 scopus 로고    scopus 로고
    • Pre-clinical whole-body fluorescence imaging: Review of instruments, methods and applications
    • Leblond F, Davis SC, Valdes PA, Pogue BW. Pre-clinical whole-body fluorescence imaging: Review of instruments, methods and applications. J Photochem Photobiol B. 2010; 98: 77-94.
    • (2010) J Photochem Photobiol B. , vol.98 , pp. 77-94
    • Leblond, F.1    Davis, S.C.2    Valdes, P.A.3    Pogue, B.W.4
  • 48
    • 77955505603 scopus 로고    scopus 로고
    • Fluorescent imaging of high-grade bladder cancer using a specific antagonist for chemokine receptor CXCR4
    • Nishizawa K, Nishiyama H, Oishi S, Tanahara N, Kotani H, Mikami Y, et al. Fluorescent imaging of high-grade bladder cancer using a specific antagonist for chemokine receptor CXCR4. Int J Cancer. 2010; 127: 1180-7.
    • (2010) Int J Cancer. , vol.127 , pp. 1180-1187
    • Nishizawa, K.1    Nishiyama, H.2    Oishi, S.3    Tanahara, N.4    Kotani, H.5    Mikami, Y.6
  • 49
    • 46649084658 scopus 로고    scopus 로고
    • Synthesis and application of fluorescein- and biotin-labeled molecular probes for the chemokine receptor CXCR4
    • Oishi S, Masuda R, Evans B, Ueda S, Goto Y, Ohno H, et al. Synthesis and application of fluorescein- and biotin-labeled molecular probes for the chemokine receptor CXCR4. Chembiochem. 2008; 9: 1154-8.
    • (2008) Chembiochem. , vol.9 , pp. 1154-1158
    • Oishi, S.1    Masuda, R.2    Evans, B.3    Ueda, S.4    Goto, Y.5    Ohno, H.6
  • 51
    • 79961104574 scopus 로고    scopus 로고
    • Peptide-functionalized luminescent iridium complexes for lifetime imaging of CXCR4 expression
    • Kuil J, Steunenberg P, Chin PT, Oldenburg J, Jalink K, Velders AH, et al. Peptide-functionalized luminescent iridium complexes for lifetime imaging of CXCR4 expression. Chembiochem. 2011; 12: 1897-903.
    • (2011) Chembiochem. , vol.12 , pp. 1897-1903
    • Kuil, J.1    Steunenberg, P.2    Chin, P.T.3    Oldenburg, J.4    Jalink, K.5    Velders, A.H.6
  • 52
    • 79955972445 scopus 로고    scopus 로고
    • Detection of CXCR4 receptors on cell surface using a fluorescent metal nanoshell
    • Zhang J, Fu Y, Li G, Zhao RY, Lakowicz JR. Detection of CXCR4 receptors on cell surface using a fluorescent metal nanoshell. J Biomed Opt. 2011; 16: 016011..
    • (2011) J Biomed Opt. , vol.16
    • Zhang, J.1    Fu, Y.2    Li, G.3    Zhao, R.Y.4    Lakowicz, J.R.5
  • 53
    • 77957926172 scopus 로고    scopus 로고
    • Antibody-protein A conjugated quantum dots for multiplexed imaging of surface receptors in living cells
    • Jin T, Tiwari DK, Tanaka S, Inouye Y, Yoshizawa K, Watanabe TM. Antibody-protein A conjugated quantum dots for multiplexed imaging of surface receptors in living cells. Mol Biosyst. 2010; 6: 2325-31.
    • (2010) Mol Biosyst. , vol.6 , pp. 2325-2331
    • Jin, T.1    Tiwari, D.K.2    Tanaka, S.3    Inouye, Y.4    Yoshizawa, K.5    Watanabe, T.M.6
  • 54
    • 82955172980 scopus 로고    scopus 로고
    • Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression
    • Kuil J, Buckle T, Oldenburg J, Yuan H, Borowsky AD, Josephson L, et al. Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression. Mol Pharm. 2011; 8: 2444-53.
    • (2011) Mol Pharm. , vol.8 , pp. 2444-2453
    • Kuil, J.1    Buckle, T.2    Oldenburg, J.3    Yuan, H.4    Borowsky, A.D.5    Josephson, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.