Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation

American Journal of Respiratory Cell and Molecular Biology

Volumn 49, Issue 2, 2013, Pages 269-278

  Mathew, Biji ^a   Jacobson, Jeffrey R ^a   Siegler, Jessica H ^a   Moitra, Jaideep ^a   Blasco, Michael ^a   Xie, Lishi ^a   Unzueta, Crystal ^a   Zhou, Tong ^a   Evenoski, Carrie ^a   Al Sakka, Mohammed ^a   Sharma, Rajesh ^a   Huey, Ben ^a   Bulent, Aydogan ^b   Smith, Brett ^b   Jayaraman, Sundararajan ^a   Reddy, Narsa M ^a   Reddy, Shekhar P ^a   Fingerle Rowson, Günter ^c   Bucala, Richard ^d   Dudek, Steven M ^a   Natarajan, Viswanathan ^a   Weichselbaum, Ralph R ^b   Garcia, Joe G N ^a   more..

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Antioxidant system; Lung vascular permeability; Macrophage migratory inhibition factor; Nrf2; Radiation pneumonitis

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE 1; HEME OXYGENASE 1; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; NQO1 PROTEIN; PEROXIREDOXIN 1; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; THIOREDOXIN REDUCTASE 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; LUNG ENDOTHELIUM; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTIAL BODY RADIATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION DOSE; RADIATION INJURY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WILD TYPE;

ACUTE LUNG INJURY; AGING; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; GAMMA RAYS; HEME OXYGENASE-1; HUMANS; HYDROGEN PEROXIDE; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; OXIDANTS; RADIATION INJURIES, EXPERIMENTAL;

EID: 84883185280     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0291OC     Document Type: Article

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