BTZO-15, an ARE-activator, ameliorates DSS- and TNBS-induced colitis in rats

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Yukitake, Hiroshi ^a   Kimura, Haruhide ^a   Suzuki, Hirobumi ^a   Tajima, Yasukazu ^a   Sato, Yoshimi ^a   Imaeda, Toshihiro ^a   Kajino, Masahiro ^a   Takizawa, Masayuki ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BTZO 15; DEXTRAN SULFATE; GASTROINTESTINAL AGENT; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE YA; HEME OXYGENASE 1; MACROPHAGE MIGRATION INHIBITION FACTOR; MYELOPEROXIDASE; NITRIC OXIDE; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIOXIDANT; BTZO 15 COMPOUND; BTZO-15 COMPOUND; ISOMERASE; MESSENGER RNA; MIF PROTEIN, RAT; PYRIDINE DERIVATIVE; THIAZINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL DEATH; COLITIS; CONTROLLED STUDY; DIARRHEA; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG STRUCTURE; ENZYME ACTIVITY; GENE EXPRESSION; INTESTINAL BLEEDING; INTESTINE EPITHELIUM CELL; LARGE INTESTINE; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RECTUM; RECTUM ULCER; TRANSCRIPTION INITIATION; WEIGHT GAIN; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PROTEIN BINDING;

RATTUS;

ANIMALS; ANTIOXIDANTS; CELL DEATH; COLITIS; DEXTRAN SULFATE; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HEME OXYGENASE-1; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; NITRIC OXIDE; PROTEIN BINDING; PYRIDINES; RATS; RECTUM; RESPONSE ELEMENTS; RNA, MESSENGER; THIAZINES; TRANSCRIPTION, GENETIC; TRINITROBENZENESULFONIC ACID;

EID: 80051504263     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023256     Document Type: Article

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