Targeted induction of endogenous NKX3-1 by small activating RNA inhibits prostate tumor growth

Prostate

Volumn 73, Issue 14, 2013, Pages 1591-1601

  Ren, Shancheng ^a,b   Kang, Moo Rim ^a   Wang, Ji ^a   Huang, Vera ^a   Place, Robert F ^a   Sun, Yinhao ^b   Li, Long Cheng ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

NKX3 1; prostate cancer; RNAa; saRNA; xenograft

Indexed keywords

DOUBLE STRANDED RNA; PROTEIN P21; PROTEIN P27; RNA; SMALL ACTIVATING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX3.1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; TUMOR XENOGRAFT;

NKX3-1; PROSTATE CANCER; RNAA; SARNA; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; CELL PHYSIOLOGICAL PROCESSES; GENES, TUMOR SUPPRESSOR; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICE; MODELS, ANIMAL; PLASMIDS; PROSTATE; PROSTATIC NEOPLASMS; RNA, DOUBLE-STRANDED; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TREATMENT OUTCOME;

EID: 84883166021     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.22709     Document Type: Article

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