Defining features and exploring chemical modifications to manipulate RNAa activity

Current Pharmaceutical Biotechnology

Volumn 11, Issue 5, 2010, Pages 518-526

  Place, Robert F ^a,b   Noonan, Emily J ^c,d   Földes Papp, Zeno ^e   Li, Long Cheng ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Argonaute 2 (Ago2); Cancer therapeutics; E cadherin; Gene promoter; p21; RNA activation (RNAa); RNA interference (RNAi); Small activating RNA (saRNA); Small interfering RNA (siRNA); Strand modifications

Indexed keywords

ARGONAUTE 2 PROTEIN; DOUBLE STRANDED RNA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; PROTEIN P21; SMALL INTERFERING RNA; UVOMORULIN;

ARTICLE; CANCER CELL; CANCER THERAPY; CHEMICAL MODIFICATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; MOLECULE; PROMOTER REGION; PROSTATE ADENOCARCINOMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

GENETIC ENGINEERING; RNA, SMALL INTERFERING;

EID: 77956599498     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920110791591463     Document Type: Article

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