Examination of Artificial MiRNA Mimics with Centered-Site Complementarity for Gene Targeting

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Zhang, Shu Guang ^a   Liu, Chun Yan ^b   Li, Li ^a   Sun, Tong Wen ^a   Luo, Yong Gang ^a   Yun, Wen Jing ^a   Zhang, Jin Ying ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b ZHENGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; MICRORNA; RECOMBINANT RNA; SMALL INTERFERING RNA;

3' UNTRANSLATED REGION; AKT1 GENE; ANIMAL CELL; ARTICLE; BCL2 GENE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; GAIN OF FUNCTION MUTATION; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE LOCATION; GENE TARGETING; GENE TECHNOLOGY; GENETIC COMPLEMENTATION; GENETIC ENGINEERING; NONHUMAN; POSTTRANSCRIPTIONAL GENE SILENCING; RAT; REPORTER GENE; VALIDATION PROCESS;

3' UNTRANSLATED REGIONS; ANIMALS; CELL LINE; CELL SURVIVAL; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENES, REPORTER; LUCIFERASES; MICRORNAS; MOLECULAR MIMICRY; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84883162255     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072062     Document Type: Article

References (30)

1. Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, et al. (2006) A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell 126: 1203-1217.
2. Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, et al. (2006) The colorectal microRNAome. Proc Natl Acad Sci U S A 103: 3687-3692.
3. Brennecke J, Stark A, Russell RB, Cohen SM, (2005) Principles of microRNA-target recognition. PLoS Biol 3: 404-418.
4. Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB, (2003) Prediction of mammalian microRNA targets. Cell 115: 787-798.
5. Lewis BP, Burge CB, Bartel DP, (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
6. Pillai RS, Bhattacharyya SN, Filipowicz W, (2007) Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol 17: 18-126.
7. Alvarez-Garcia I, Miska EA, (2005) MicroRNA functions in animal development and human disease. Development 132: 4653-4662.
8. Kloosterman WP, Plasterk RHA, (2006) The diverse functions of microRNAs in animal development and disease. Dev Cell 11: 441-450.
9. Wang Y, Taniguchi T. MicroRNAs and DNA damage response: implications for cancer therapy. Cell Cycle 12: 32-42.
10. MicroRNA regulation, its effects on cellular transcriptome in Human Duskova K, Nagilla P, Le HS, Iyer P, Thalamuthu A, Martinson J, et al. (2013) Immunodeficiency Virus-1 (HIV-1) infected individuals with distinct viral load and CD4 cell counts. BMC Infect Dis. 2013 May 30 13: 250 doi:10.1186/1471-2334-13-250.
11. Wang Z (2009) MicroRNA-Interference Technologies. Springer-Verlag, New York, USA.
12. Wang Z, (2011) The guideline of the design and validation of miRNA mimics. Methods Mol Biol 676: 211-224.
13. Sun D, Melegari M, Sridhar S, Rogler CE, Zhu L, (2006) Multi-miRNA hairpin method that improves gene knockdown efficiency and provides linked multi-gene knockdown. Biotechniques 41: 59-63.
14. Lu Y, Zhang Y, Wang N, Pan Z, Gao X, et al. (2010) Control of experimental atrial fibrillation by microRNA-328. Circulation 122: 2378-2387.
15. Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, et al. (2005) Silencing of microRNAs in vivo with 'antagomirs'. Nature 438: 685-689.
16. Ebert MS, Neilson JR, Sharp PA, (2007) MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods 4: 721-726.
17. Doench JG, Sharp PA, (2004) Specificity of microRNA target selection in translational repression. Genes Dev 18: 504-511.
18. Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, et al. (2007) MicroRNA targeting pecificity in mammals: determinants beyond seed pairing. Mol Cell 27: 91-105.
19. Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, et al. (2003) The microRNAs of Caenorhabditis elegans. Genes Dev 17: 991-1008.
20. Shin C, Nam JW, Farh KK, Chiang HR, Shkumatava A, et al. (2010) Expanding the microRNA targeting code: functional sites with centered pairing. Mol Cell 38: 789-802.
21. Luo X, Pan Z, Shan H, Xiao J, Sun X, Wang N, et al. (2013) MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. J Clin Invest 123: 1939-1951.
22. Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
23. Xiao J, Lin H, Luo X, Luo X-Y, Wang Z, (2011) miRNA-605 joins the p53 network to form a p53:miRNA-605:Mdm2 positive feedback loop in response to cellular stress. EMBO J 30: 534-532.
24. Yang B, Lin H, Xiao J, Lu Y, Luo X, et al. (2007) The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med 13: 486-491.
25. Xu C, Lu Y, Lin H, Xiao J, Wang H, et al. (2007) The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis via targeting HSP60/HSP70 and caspase-9 in cardiomyocytes. J Cell Sci 120: 3045-3052.
26. Yekta S, Shih IH, Bartel DP, (2004) MicroRNA-directed cleavage of HOXB8 mRNA. Science 304: 594-596.
27. Shin C, (2008) Cleavage of the star strand facilitates assembly of some MicroRNAs into Ago2-containing silencing complexes in mammals. Mol Cells 26: 308-313.
28. Elbashir SM, Lendeckel W, Tuschl T, (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 15: 188-200.
29. Zeng Y, Yi R, Cullen BR, (2003) MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci USA 100: 9779-9784.
30. Doench JG, Petersen CP, Sharp PA, (2003) siRNAs can function as miRNAs. Genes Dev 17: 438-442.