메뉴 건너뛰기




Volumn 4, Issue 5, 2013, Pages

Synergistic effect of Indian hedgehog and bone morphogenetic protein-2 gene transfer to increase the osteogenic potential of human mesenchymal stem cells

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; DNA; OSTEOCALCIN; OSTEOPONTIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA;

EID: 84883158497     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt316     Document Type: Article
Times cited : (27)

References (42)
  • 1
    • 0033065993 scopus 로고    scopus 로고
    • Bone repair techniques, bone graft, and bone graft substitutes
    • 10101312
    • Bone repair techniques, bone graft, and bone graft substitutes. Perry CR, Clin Orthop Relat Res 1999 360 71 86 10101312
    • (1999) Clin Orthop Relat Res , vol.360 , pp. 71-86
    • Perry, C.R.1
  • 3
    • 46149108855 scopus 로고    scopus 로고
    • Treating segmental bone defects: A new technique
    • 10.1053/j.jfas.2008.04.006 18590901
    • Treating segmental bone defects: a new technique. Clements JR, Carpenter BB, Pourciau JK, J Foot Ankle Surg 2008 47 350 356 10.1053/j.jfas.2008.04.006 18590901
    • (2008) J Foot Ankle Surg , vol.47 , pp. 350-356
    • Clements, J.R.1    Carpenter, B.B.2    Pourciau, J.K.3
  • 5
    • 76849109024 scopus 로고    scopus 로고
    • The design and use of animal models for translational research in bone tissue engineering and regenerative medicine
    • 19891542
    • The design and use of animal models for translational research in bone tissue engineering and regenerative medicine. Muschler GF, Raut VP, Patterson TE, Wenke JC, Hollinger JO, Tissue Eng Part B Rev 2010 16 123 145 19891542
    • (2010) Tissue Eng Part B Rev , vol.16 , pp. 123-145
    • Muschler, G.F.1    Raut, V.P.2    Patterson, T.E.3    Wenke, J.C.4    Hollinger, J.O.5
  • 9
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: Paradigms and principles
    • 10.1101/gad.938601 11731473
    • Hedgehog signaling in animal development: paradigms and principles. Ingham PW, McMahon AP, Genes Dev 2001 15 3059 3087 10.1101/gad.938601 11731473
    • (2001) Genes Dev , vol.15 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 10
    • 57049085407 scopus 로고    scopus 로고
    • G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling
    • 10.1038/nature07459 18987629
    • G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling. Ogden SK, Fei DL, Schilling NS, Ahmed YF, Hwa J, Robbins DJ, Nature 2008 456 967 970 10.1038/nature07459 18987629
    • (2008) Nature , vol.456 , pp. 967-970
    • Ogden, S.K.1    Fei, D.L.2    Schilling, N.S.3    Ahmed, Y.F.4    Hwa, J.5    Robbins, D.J.6
  • 11
    • 0032848136 scopus 로고    scopus 로고
    • Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling
    • 10433919
    • Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H, Development 1999 126 3915 3924 10433919
    • (1999) Development , vol.126 , pp. 3915-3924
    • Sasaki, H.1    Nishizaki, Y.2    Hui, C.3    Nakafuku, M.4    Kondoh, H.5
  • 12
    • 84876701150 scopus 로고    scopus 로고
    • Preclinical and clinical studies on the use of growth factors for bone repair: A systematic review
    • 10.2174/1574888X11308030011 23317434
    • Preclinical and clinical studies on the use of growth factors for bone repair: a systematic review. Fisher DM, Wong JM, Crowley C, Khan WS, Curr Stem Cell Res Ther 2013 8 260 268 10.2174/1574888X11308030011 23317434
    • (2013) Curr Stem Cell Res Ther , vol.8 , pp. 260-268
    • Fisher, D.M.1    Wong, J.M.2    Crowley, C.3    Khan, W.S.4
  • 13
    • 70449527663 scopus 로고    scopus 로고
    • The synergistic effect of autograft and BMP-7 in the treatment of atrophic nonunions
    • 10.1007/s11999-009-0846-2 19396502
    • The synergistic effect of autograft and BMP-7 in the treatment of atrophic nonunions. Giannoudis PV, Kanakaris NK, Dimitriou R, Gill I, Kolimarala V, Montgomery RJ, Clin Orthop Relat Res 2009 467 3239 3248 10.1007/s11999-009- 0846-2 19396502
    • (2009) Clin Orthop Relat Res , vol.467 , pp. 3239-3248
    • Giannoudis, P.V.1    Kanakaris, N.K.2    Dimitriou, R.3    Gill, I.4    Kolimarala, V.5    Montgomery, R.J.6
  • 14
    • 84856698574 scopus 로고    scopus 로고
    • Use of bone morphogenetic proteins in spinal fusion surgery for older adults with lumbar stenosis: Trends, complications, repeat surgery, and charges
    • 10.1097/BRS.0b013e31821bfa3a 21494195
    • Use of bone morphogenetic proteins in spinal fusion surgery for older adults with lumbar stenosis: trends, complications, repeat surgery, and charges. Deyo RA, Ching A, Matsen L, Martin BI, Kreuter W, Jarvik JG, Angier H, Mirza SK, Spine 2012 37 222 230 10.1097/BRS.0b013e31821bfa3a 21494195
    • (2012) Spine , vol.37 , pp. 222-230
    • Deyo, R.A.1    Ching, A.2    Matsen, L.3    Martin, B.I.4    Kreuter, W.5    Jarvik, J.G.6    Angier, H.7    Mirza, S.K.8
  • 15
    • 0031728879 scopus 로고    scopus 로고
    • Common molecular pathways in skeletal morphogenesis and repair
    • 10.1111/j.1749-6632.1998.tb10105.x 9917830
    • Common molecular pathways in skeletal morphogenesis and repair. Ferguson CM, Miclau T, Hu D, Alpern E, Helms JA, Ann NY Acad Sci 1998 857 33 42 10.1111/j.1749-6632.1998.tb10105.x 9917830
    • (1998) Ann NY Acad Sci , vol.857 , pp. 33-42
    • Ferguson, C.M.1    Miclau, T.2    Hu, D.3    Alpern, E.4    Helms, J.A.5
  • 16
    • 0002452569 scopus 로고    scopus 로고
    • Developmental roles and clinical significance of hedgehog signaling
    • 12509125
    • Developmental roles and clinical significance of hedgehog signaling. McMahon AP, Ingham PW, Tabin CJ, Curr Top Dev Biol 2003 53 1 114 12509125
    • (2003) Curr Top Dev Biol , vol.53 , pp. 1-114
    • McMahon, A.P.1    Ingham, P.W.2    Tabin, C.J.3
  • 17
    • 0036377961 scopus 로고    scopus 로고
    • Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells
    • 10.1016/S0736-0266(02)00018-9 12382974
    • Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells. Noth U, Osyczka AM, Tuli R, Hickok NJ, Danielson KG, Tuan RS, J Orthop Res 2002 20 1060 1069 10.1016/S0736-0266(02)00018-9 12382974
    • (2002) J Orthop Res , vol.20 , pp. 1060-1069
    • Noth, U.1    Osyczka, A.M.2    Tuli, R.3    Hickok, N.J.4    Danielson, K.G.5    Tuan, R.S.6
  • 18
    • 66249107073 scopus 로고    scopus 로고
    • Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer
    • 10.1089/ten.tea.2007.0252 18826340
    • Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Steinert AF, Palmer GD, Pilapil C, Noth U, Evans CH, Ghivizzani SC, Tissue Eng Part A 2009 15 1127 1139 10.1089/ten.tea.2007.0252 18826340
    • (2009) Tissue Eng Part A , vol.15 , pp. 1127-1139
    • Steinert, A.F.1    Palmer, G.D.2    Pilapil, C.3    Noth, U.4    Evans, C.H.5    Ghivizzani, S.C.6
  • 20
    • 79952117840 scopus 로고    scopus 로고
    • Ovine bone- and marrow-derived progenitor cells and their potential for scaffold-based bone tissue engineering applications in vitro and in vivo
    • 10.1002/term.276 20568083
    • Ovine bone- and marrow-derived progenitor cells and their potential for scaffold-based bone tissue engineering applications in vitro and in vivo. Reichert JC, Woodruff MA, Friis T, Quent VM, Gronthos S, Duda GN, Schutz MA, Hutmacher DW, J Tissue Eng Regen Med 2010 4 565 576 10.1002/term.276 20568083
    • (2010) J Tissue Eng Regen Med , vol.4 , pp. 565-576
    • Reichert, J.C.1    Woodruff, M.A.2    Friis, T.3    Quent, V.M.4    Gronthos, S.5    Duda, G.N.6    Schutz, M.A.7    Hutmacher, D.W.8
  • 21
    • 78650203492 scopus 로고    scopus 로고
    • Activation of the Hh pathway in periosteum-derived mesenchymal stem cells induces bone formation in vivo: Implication for postnatal bone repair
    • 10.2353/ajpath.2010.100060 20971735
    • Activation of the Hh pathway in periosteum-derived mesenchymal stem cells induces bone formation in vivo: implication for postnatal bone repair. Wang Q, Huang C, Zeng F, Xue M, Zhang X, Am J Pathol 2010 177 3100 3111 10.2353/ajpath.2010.100060 20971735
    • (2010) Am J Pathol , vol.177 , pp. 3100-3111
    • Wang, Q.1    Huang, C.2    Zeng, F.3    Xue, M.4    Zhang, X.5
  • 22
    • 13444302715 scopus 로고    scopus 로고
    • Sequential roles of Hedgehog and Wnt signaling in osteoblast development
    • 15576404
    • Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F, Development 2005 132 49 60 15576404
    • (2005) Development , vol.132 , pp. 49-60
    • Hu, H.1    Hilton, M.J.2    Tu, X.3    Yu, K.4    Ornitz, D.M.5    Long, F.6
  • 23
    • 84865330310 scopus 로고    scopus 로고
    • Gene delivery to bone
    • 10.1016/j.addr.2012.03.013 22480730
    • Gene delivery to bone. Evans CH, Adv Drug Deliv Rev 2012 64 1331 1340 10.1016/j.addr.2012.03.013 22480730
    • (2012) Adv Drug Deliv Rev , vol.64 , pp. 1331-1340
    • Evans, C.H.1
  • 25
    • 0346996354 scopus 로고    scopus 로고
    • Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells
    • 10.1016/j.bone.2003.07.004 14678849
    • Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells. van der Horst G, Farih-Sips H, Lowik CW, Karperien M, Bone 2003 33 899 910 10.1016/j.bone.2003.07.004 14678849
    • (2003) Bone , vol.33 , pp. 899-910
    • Van Der Horst, G.1    Farih-Sips, H.2    Lowik, C.W.3    Karperien, M.4
  • 27
    • 57549091599 scopus 로고    scopus 로고
    • Biodegradable poly(epsilon-caprolactone) nanowires for bone tissue engineering applications
    • 10.1016/j.biomaterials.2008.10.022 19012962
    • Biodegradable poly(epsilon-caprolactone) nanowires for bone tissue engineering applications. Porter JR, Henson A, Popat KC, Biomaterials 2009 30 780 788 10.1016/j.biomaterials.2008.10.022 19012962
    • (2009) Biomaterials , vol.30 , pp. 780-788
    • Porter, J.R.1    Henson, A.2    Popat, K.C.3
  • 28
    • 1842611651 scopus 로고    scopus 로고
    • Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton
    • 10.1242/dev.01006 14973297
    • Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP, Development 2004 131 1309 1318 10.1242/dev.01006 14973297
    • (2004) Development , vol.131 , pp. 1309-1318
    • Long, F.1    Chung, U.I.2    Ohba, S.3    McMahon, J.4    Kronenberg, H.M.5    McMahon, A.P.6
  • 29
    • 0035106438 scopus 로고    scopus 로고
    • Bone anabolic effects of sonic/indian hedgehog are mediated by bmp-2/4-dependent pathways in the neonatal rat metatarsal model
    • 10.1210/en.142.2.940 11159867
    • Bone anabolic effects of sonic/indian hedgehog are mediated by bmp-2/4-dependent pathways in the neonatal rat metatarsal model. Krishnan V, Ma Y, Moseley J, Geiser A, Friant S, Frolik C, Endocrinology 2001 142 940 947 10.1210/en.142.2.940 11159867
    • (2001) Endocrinology , vol.142 , pp. 940-947
    • Krishnan, V.1    Ma, Y.2    Moseley, J.3    Geiser, A.4    Friant, S.5    Frolik, C.6
  • 30
    • 65249135916 scopus 로고    scopus 로고
    • Activation of hedgehog signaling inhibits osteoblast differentiation of human mesenchymal stem cells
    • 10.1634/stemcells.2008-0888 19096040
    • Activation of hedgehog signaling inhibits osteoblast differentiation of human mesenchymal stem cells. Plaisant M, Fontaine C, Cousin W, Rochet N, Dani C, Peraldi P, Stem Cells 2009 27 703 713 10.1634/stemcells.2008-0888 19096040
    • (2009) Stem Cells , vol.27 , pp. 703-713
    • Plaisant, M.1    Fontaine, C.2    Cousin, W.3    Rochet, N.4    Dani, C.5    Peraldi, P.6
  • 32
    • 84876213011 scopus 로고    scopus 로고
    • Transcriptional regulatory cascades in runx2-dependent bone development
    • 10.1089/ten.teb.2012.0527 23150948
    • Transcriptional regulatory cascades in runx2-dependent bone development. Liu TM, Lee EH, Tissue Eng Part B Rev 2013 19 254 263 10.1089/ten.teb.2012.0527 23150948
    • (2013) Tissue Eng Part B Rev , vol.19 , pp. 254-263
    • Liu, T.M.1    Lee, E.H.2
  • 33
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • 10.1016/S0092-8674(00)80257-3 9182762
    • Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G, Cell 1997 89 747 754 10.1016/S0092-8674(00)80257-3 9182762
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 34
    • 0035831510 scopus 로고    scopus 로고
    • Cbfa1 contributes to the osteoblast-specific expression of type i collagen genes
    • 10.1074/jbc.M006215200 11106645
    • Cbfa1 contributes to the osteoblast-specific expression of type I collagen genes. Kern B, Shen J, Starbuck M, Karsenty G, J Biol Chem 2001 276 7101 7107 10.1074/jbc.M006215200 11106645
    • (2001) J Biol Chem , vol.276 , pp. 7101-7107
    • Kern, B.1    Shen, J.2    Starbuck, M.3    Karsenty, G.4
  • 35
    • 0001516132 scopus 로고
    • Characterization of a gamma-carboxyglutamic acid-containing protein from bone
    • 10.1073/pnas.73.5.1447 1064018
    • Characterization of a gamma-carboxyglutamic acid-containing protein from bone. Price PA, Otsuka AA, Poser JW, Kristaponis J, Raman N, Proc Natl Acad Sci USA 1976 73 1447 1451 10.1073/pnas.73.5.1447 1064018
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 1447-1451
    • Price, P.A.1    Otsuka, A.A.2    Poser, J.W.3    Kristaponis, J.4    Raman, N.5
  • 36
    • 0031665086 scopus 로고    scopus 로고
    • Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin
    • 10.1016/S8756-3282(98)00092-1 9737340
    • Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin. Boskey AL, Gadaleta S, Gundberg C, Doty SB, Ducy P, Karsenty G, Bone 1998 23 187 196 10.1016/S8756-3282(98)00092-1 9737340
    • (1998) Bone , vol.23 , pp. 187-196
    • Boskey, A.L.1    Gadaleta, S.2    Gundberg, C.3    Doty, S.B.4    Ducy, P.5    Karsenty, G.6
  • 37
    • 0032759219 scopus 로고    scopus 로고
    • Bone sialoprotein
    • 10.1177/10454411990100010401 10759428
    • Bone sialoprotein. Ganss B, Kim RH, Sodek J, Crit Rev Oral Biol Med 1999 10 79 98 10.1177/10454411990100010401 10759428
    • (1999) Crit Rev Oral Biol Med , vol.10 , pp. 79-98
    • Ganss, B.1    Kim, R.H.2    Sodek, J.3
  • 39
    • 1542561305 scopus 로고    scopus 로고
    • Over-expression of bone sialoprotein enhances bone metastasis of human breast cancer cells in a mouse model
    • 12963984
    • Over-expression of bone sialoprotein enhances bone metastasis of human breast cancer cells in a mouse model. Zhang JH, Tang J, Wang J, Ma W, Zheng W, Yoneda T, Chen J, Int J Oncol 2003 23 1043 1048 12963984
    • (2003) Int J Oncol , vol.23 , pp. 1043-1048
    • Zhang, J.H.1    Tang, J.2    Wang, J.3    Ma, W.4    Zheng, W.5    Yoneda, T.6    Chen, J.7
  • 40
    • 69249156419 scopus 로고    scopus 로고
    • Progress and Prospects: Genetic treatments for disorders of bones and joints
    • 10.1038/gt.2009.73 19675584
    • Progress and Prospects: genetic treatments for disorders of bones and joints. Evans CH, Ghivizzani SC, Robbins PD, Gene Ther 2009 16 944 952 10.1038/gt.2009.73 19675584
    • (2009) Gene Ther , vol.16 , pp. 944-952
    • Evans, C.H.1    Ghivizzani, S.C.2    Robbins, P.D.3
  • 41
    • 34848904829 scopus 로고    scopus 로고
    • Adenoviral vectors for gene therapy
    • 10.1007/s12033-007-0021-5 17827541
    • Adenoviral vectors for gene therapy. Douglas JT, Mol Biotechnol 2007 36 71 80 10.1007/s12033-007-0021-5 17827541
    • (2007) Mol Biotechnol , vol.36 , pp. 71-80
    • Douglas, J.T.1
  • 42
    • 77955485475 scopus 로고    scopus 로고
    • Gene therapy for bone healing
    • 20569532
    • Gene therapy for bone healing. Evans CH, Expert Rev Mol Med 2010 12 18 20569532
    • (2010) Expert Rev Mol Med , vol.12 , pp. 518
    • Evans, C.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.