-
1
-
-
84867756352
-
Catalytic selective synthesis
-
Mahatthananchai, J., Dumas, A. M. & Bode, J. W. Catalytic selective synthesis. Angew. Chem. Int. Ed. 51, 10954-10990 (2012).
-
(2012)
Angew. Chem. Int. Ed.
, vol.51
, pp. 10954-10990
-
-
Mahatthananchai, J.1
Dumas, A.M.2
Bode, J.W.3
-
2
-
-
44249098800
-
Natural products to drugs: Natural product-derived compounds in clinical trials
-
Butler, M. S. Natural products to drugs: natural product-derived compounds in clinical trials. Nat. Prod. Rep. 25, 475-516 (2008).
-
(2008)
Nat. Prod. Rep.
, vol.25
, pp. 475-516
-
-
Butler, M.S.1
-
3
-
-
44049095632
-
Protein-glycan interactions in the control of innate and adaptive immune responses
-
van Kooyk, Y. & Rabinovich, G. A. Protein-glycan interactions in the control of innate and adaptive immune responses. Nature Immunol. 9, 593-601 (2008).
-
(2008)
Nature Immunol.
, vol.9
, pp. 593-601
-
-
Van Kooyk, Y.1
Rabinovich, G.A.2
-
4
-
-
0035937505
-
Intracellular functions of N-linked glycans
-
Helenius, A. & Aebi, M. Intracellular functions of N-linked glycans. Science 291, 2364-2369 (2001).
-
(2001)
Science
, vol.291
, pp. 2364-2369
-
-
Helenius, A.1
Aebi, M.2
-
5
-
-
0031127564
-
The role of carbohydrates in biologically active natural products
-
Weymouth-Wilson, A. C. The role of carbohydrates in biologically active natural products. Nat. Prod. Rep. 14, 99-110 (1997).
-
(1997)
Nat. Prod. Rep.
, vol.14
, pp. 99-110
-
-
Weymouth-Wilson, A.C.1
-
6
-
-
79952033077
-
Natural glycoconjugates with antitumor activity
-
La Ferla, B. et al. Natural glycoconjugates with antitumor activity. Nat. Prod. Rep. 28, 630-648 (2011).
-
(2011)
Nat. Prod. Rep.
, vol.28
, pp. 630-648
-
-
La Ferla, B.1
-
7
-
-
26044440288
-
Automated synthesis of oligosaccharides as a basis for drug discovery
-
Seeberger, P. H. & Werz, D. B. Automated synthesis of oligosaccharides as a basis for drug discovery. Nature Rev. Drug. Discov. 4, 751-763 (2005).
-
(2005)
Nature Rev. Drug. Discov.
, vol.4
, pp. 751-763
-
-
Seeberger, P.H.1
Werz, D.B.2
-
8
-
-
61849111654
-
New principles for glycoside-bond formation
-
Zhu, X. & Schmidt, R. R. New principles for glycoside-bond formation. Angew. Chem. Int. Ed. 48, 1900-1934 (2009).
-
(2009)
Angew. Chem. Int. Ed.
, vol.48
, pp. 1900-1934
-
-
Zhu, X.1
Schmidt, R.R.2
-
9
-
-
83455176937
-
Toward automated oligosaccharide synthesis
-
Hsu, C. H., Hung, S. C., Wu, C. Y. & Wong, C. H. Toward automated oligosaccharide synthesis. Angew. Chem. Int. Ed. 50, 11872-11923 (2011).
-
(2011)
Angew. Chem. Int. Ed.
, vol.50
, pp. 11872-11923
-
-
Hsu, C.H.1
Hung, S.C.2
Wu, C.Y.3
Wong, C.H.4
-
10
-
-
84867080246
-
Solving the convergence problem in the synthesis of triantennary N-glycan relevant to prostate-specific membrane antigen (PSMA)
-
Walczak, M. A. & Danishefsky, S. J. Solving the convergence problem in the synthesis of triantennary N-glycan relevant to prostate-specific membrane antigen (PSMA). J. Am. Chem. Soc. 134, 16430-16433 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 16430-16433
-
-
Walczak, M.A.1
Danishefsky, S.J.2
-
11
-
-
0015927426
-
Remote oxidation of steroids by photolysis of attached benzophenone groups
-
Breslow, R. et al. Remote oxidation of steroids by photolysis of attached benzophenone groups. J. Am. Chem. Soc. 95, 3251-3262 (1973).
-
(1973)
J. Am. Chem. Soc.
, vol.95
, pp. 3251-3262
-
-
Breslow, R.1
-
12
-
-
0017764981
-
Selective halogenation of steroids using attached aryl iodide templates
-
Breslow, R. et al. Selective halogenation of steroids using attached aryl iodide templates. J. Am. Chem. Soc. 99, 905-915 (1977).
-
(1977)
J. Am. Chem. Soc.
, vol.99
, pp. 905-915
-
-
Breslow, R.1
-
13
-
-
33845553152
-
Catalytic multiple template-directed steroid chlorinations
-
Breslow, R. & Heyer, D. Catalytic multiple template-directed steroid chlorinations. J. Am. Chem. Soc. 104, 2045-2046 (1982).
-
(1982)
J. Am. Chem. Soc.
, vol.104
, pp. 2045-2046
-
-
Breslow, R.1
Heyer, D.2
-
14
-
-
33748581386
-
Site-selective derivatization and remodeling of erythromycin A by using simple peptide-based chiral catalysts
-
Lewis, C. A. & Miller, S. J. Site-selective derivatization and remodeling of erythromycin A by using simple peptide-based chiral catalysts. Angew. Chem. Int. Ed. 45, 5616-5619 (2006).
-
(2006)
Angew. Chem. Int. Ed.
, vol.45
, pp. 5616-5619
-
-
Lewis, C.A.1
Miller, S.J.2
-
15
-
-
40949096433
-
A predictably selective aliphatic C-H oxidation reaction for complex molecule synthesis
-
Chen, M. S. & White, M. C. A predictably selective aliphatic C-H oxidation reaction for complex molecule synthesis. Science 318, 783-787 (2007).
-
(2007)
Science
, vol.318
, pp. 783-787
-
-
Chen, M.S.1
White, M.C.2
-
16
-
-
77955848701
-
Perfectly regioselective acylation of a cardiac glycoside, digitoxin, via catalytic amplification of the intrinsic reactivity
-
Yoshida, K., Furuta, T. & Kawabata, T. Perfectly regioselective acylation of a cardiac glycoside, digitoxin, via catalytic amplification of the intrinsic reactivity. Tetrahedron Lett. 51, 4830-4832 (2010).
-
(2010)
Tetrahedron Lett.
, vol.51
, pp. 4830-4832
-
-
Yoshida, K.1
Furuta, T.2
Kawabata, T.3
-
17
-
-
79959554069
-
Regioselective reactions for programmable resveratrol oligomer synthesis
-
Snyder, S. A., Gollner, A. & Chiriac, M. I. Regioselective reactions for programmable resveratrol oligomer synthesis. Nature 474, 461-466 (2011).
-
(2011)
Nature
, vol.474
, pp. 461-466
-
-
Snyder, S.A.1
Gollner, A.2
Chiriac, M.I.3
-
18
-
-
84863496539
-
Innate and guided C-H functionalization logic
-
Bruckl, T., Baxter, R. D., Ishihara, Y. & Baran, P. S. Innate and guided C-H functionalization logic. Acc. Chem. Res. 45, 826-839 (2012).
-
(2012)
Acc. Chem. Res.
, vol.45
, pp. 826-839
-
-
Bruckl, T.1
Baxter, R.D.2
Ishihara, Y.3
Baran, P.S.4
-
19
-
-
84859592619
-
Site-selective bromination of vancomycin
-
Pathak, T. P. & Miller, S. J. Site-selective bromination of vancomycin. J. Am. Chem. Soc. 134, 6120-6123 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 6120-6123
-
-
Pathak, T.P.1
Miller, S.J.2
-
20
-
-
84870201767
-
Electronic tuning of site-selectivity
-
Wilcock, B. C. et al. Electronic tuning of site-selectivity. Nature Chem. 4, 996-1003 (2012).
-
(2012)
Nature Chem.
, vol.4
, pp. 996-1003
-
-
Wilcock, B.C.1
-
21
-
-
84862168336
-
Catalytic site-selective thiocarbonylations and deoxygenations of vancomycin reveal hydroxyl-dependent conformational effects
-
Fowler, B. S., Laemmerhold, K. M. & Miller, S. J. Catalytic site-selective thiocarbonylations and deoxygenations of vancomycin reveal hydroxyl-dependent conformational effects. J. Am. Chem. Soc. 134, 9755-9761 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 9755-9761
-
-
Fowler, B.S.1
Laemmerhold, K.M.2
Miller, S.J.3
-
22
-
-
84875134430
-
Synthesis of cardiac glycoside analogs by catalyst-controlled, regioselective glycosylation of digitoxin
-
Beale, T. M. & Taylor, M. S. Synthesis of cardiac glycoside analogs by catalyst-controlled, regioselective glycosylation of digitoxin. Org. Lett. 15, 1358-1361 (2013).
-
(2013)
Org. Lett.
, vol.15
, pp. 1358-1361
-
-
Beale, T.M.1
Taylor, M.S.2
-
23
-
-
84878634623
-
Chemical tailoring of teicoplanin with site-selective reactions
-
Pathak, T. P. & Miller, S. J. Chemical tailoring of teicoplanin with site-selective reactions. J. Am. Chem. Soc. 135, 8415-8422 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 8415-8422
-
-
Pathak, T.P.1
Miller, S.J.2
-
24
-
-
84868618354
-
Catalyst-controlled regioselective reactions of carbohydrate derivatives
-
Lee, D. & Taylor, M. S. Catalyst-controlled regioselective reactions of carbohydrate derivatives. Synthesis 44, 3421-3431 (2012).
-
(2012)
Synthesis
, vol.44
, pp. 3421-3431
-
-
Lee, D.1
Taylor, M.S.2
-
25
-
-
35549002267
-
A catalytic one-step process for the chemo-and regioselective acylation of monosaccharides
-
Kawabata, T., Muramatsu, W., Nishio, T., Shibata, T. & Schedel, H. A catalytic one-step process for the chemo-and regioselective acylation of monosaccharides. J. Am. Chem. Soc. 129, 12890-12895 (2007).
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 12890-12895
-
-
Kawabata, T.1
Muramatsu, W.2
Nishio, T.3
Shibata, T.4
Schedel, H.5
-
26
-
-
67650487533
-
Nonenzymatic regioselective acylation of carbohydrates
-
Kawabata, T. & Furuta, T. Nonenzymatic regioselective acylation of carbohydrates. Chem. Lett. 38, 640-647 (2009).
-
(2009)
Chem. Lett.
, vol.38
, pp. 640-647
-
-
Kawabata, T.1
Furuta, T.2
-
27
-
-
0142217515
-
A peptide-based catalyst approach to regioselective functionalization of carbohydrates
-
Griswold, K. S. & Miller, S. J. A peptide-based catalyst approach to regioselective functionalization of carbohydrates. Tetrahedron 59, 8869-8875 (2003).
-
(2003)
Tetrahedron
, vol.59
, pp. 8869-8875
-
-
Griswold, K.S.1
Miller, S.J.2
-
28
-
-
80052323742
-
Regioselective activation of glycosyl acceptors by a diarylborinic acid-derived catalyst
-
Gouliaras, C., Lee, D., Chan, L. & Taylor, M. S. Regioselective activation of glycosyl acceptors by a diarylborinic acid-derived catalyst. J. Am. Chem. Soc. 133, 13926-13929 (2011).
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 13926-13929
-
-
Gouliaras, C.1
Lee, D.2
Chan, L.3
Taylor, M.S.4
-
29
-
-
79958845198
-
Regioselective alkylation of carbohydrate derivatives catalyzed by a diarylborinic acid derivative
-
Chan, L. & Taylor, M. S. Regioselective alkylation of carbohydrate derivatives catalyzed by a diarylborinic acid derivative. Org. Lett. 13, 3090-3093 (2011).
-
(2011)
Org. Lett.
, vol.13
, pp. 3090-3093
-
-
Chan, L.1
Taylor, M.S.2
-
30
-
-
79952765683
-
Borinic acid-catalyzed regioselective acylation of carbohydrate derivatives
-
Lee, D. & Taylor, M. S. Borinic acid-catalyzed regioselective acylation of carbohydrate derivatives. J. Am. Chem. Soc. 133, 3724-3727 (2011).
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 3724-3727
-
-
Lee, D.1
Taylor, M.S.2
-
31
-
-
84862068667
-
Borinic acid-catalyzed monoacylation, sulfonylation and alkylation of diols and carbohydrates: Expansion of substrate scope and mechanistic studies
-
Lee, D., Williamson, C. L., Chan, L. & Taylor, M. S. Regioselective, borinic acid-catalyzed monoacylation, sulfonylation and alkylation of diols and carbohydrates: expansion of substrate scope and mechanistic studies. J. Am. Chem. Soc. 134, 8260-8267 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 8260-8267
-
-
Lee, D.1
Williamson, C.L.2
Chan, L.3
Regioselective, S.T.M.4
-
32
-
-
0036962906
-
Regioselective benzoylation of 6-O-protected and 4, 6-O-diprotected hexopyranosides as promoted by chiral and achiral ditertiary 1, 2-diamines
-
Hu, G. & Vasella, A. Regioselective benzoylation of 6-O-protected and 4, 6-O-diprotected hexopyranosides as promoted by chiral and achiral ditertiary 1, 2-diamines. Helv. Chim. Acta 85, 4369-4391 (2002).
-
(2002)
Helv. Chim. Acta
, vol.85
, pp. 4369-4391
-
-
Hu, G.1
Vasella, A.2
-
33
-
-
0015101706
-
Entropic contributions to rate accelerations in enzymic and intramolecular reactions and chelate effect
-
Page, M. I. & Jencks, W. P. Entropic contributions to rate accelerations in enzymic and intramolecular reactions and chelate effect. Proc. Natl Acad. Sci. USA 68, 1678-1683 (1971).
-
(1971)
Proc. Natl Acad. Sci. USA
, vol.68
, pp. 1678-1683
-
-
Page, M.I.1
Jencks, W.P.2
-
34
-
-
2342420346
-
Structure of Kre2p/Mnt1p: A yeast a 1, 2-mannosyltransferase involved in mannoprotein biosynthesis
-
Lobsanov, Y. D. et al. Structure of Kre2p/Mnt1p: a yeast a 1, 2-mannosyltransferase involved in mannoprotein biosynthesis. J. Biol. Chem. 279, 17921-17931 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 17921-17931
-
-
Lobsanov, Y.D.1
-
35
-
-
80051776167
-
Scaffolding catalysts: Highly enantioselective desymmetrization reactions
-
Sun, X., Worthy, A. D. & Tan, K. L. Scaffolding catalysts: highly enantioselective desymmetrization reactions. Angew. Chem. Int. Ed. 50, 8167-8171 (2011).
-
(2011)
Angew. Chem. Int. Ed.
, vol.50
, pp. 8167-8171
-
-
Sun, X.1
Worthy, A.D.2
Tan, K.L.3
-
36
-
-
84860817719
-
Site-selective catalysis: Toward a regiodivergent resolution of 1, 2-diols
-
Worthy, A. D., Sun, X. & Tan, K. L. Site-selective catalysis: toward a regiodivergent resolution of 1, 2-diols. J. Am. Chem. Soc. 134, 7321-7324 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 7321-7324
-
-
Worthy, A.D.1
Sun, X.2
Tan, K.L.3
-
37
-
-
33748413162
-
Enantioselective silyl protection of alcohols catalysed by an amino-acid-based small molecule
-
Zhao, Y., Rodrigo, J., Hoveyda, A. H. & Snapper, M. L. Enantioselective silyl protection of alcohols catalysed by an amino-acid-based small molecule. Nature 443, 67-70 (2006).
-
(2006)
Nature
, vol.443
, pp. 67-70
-
-
Zhao, Y.1
Rodrigo, J.2
Hoveyda, A.H.3
Snapper, M.L.4
-
38
-
-
0035819659
-
Modified guanidines as chiral superbases: The first example of asymmetric silylation of secondary alcohols
-
Isobe, T., Fukuda, K., Araki, Y. & Ishikawa, T. Modified guanidines as chiral superbases: the first example of asymmetric silylation of secondary alcohols. Chem. Commun. 7, 243-244 (2001).
-
(2001)
Chem. Commun.
, vol.7
, pp. 243-244
-
-
Isobe, T.1
Fukuda, K.2
Araki, Y.3
Ishikawa, T.4
-
39
-
-
77949779992
-
Asymmetric Si-O coupling of alcohols
-
Weickgenannt, A., Mewald, M. & Oestreich, M. Asymmetric Si-O coupling of alcohols. Org. Biomol. Chem. 8, 1497-1504 (2010).
-
(2010)
Org. Biomol. Chem.
, vol.8
, pp. 1497-1504
-
-
Weickgenannt, A.1
Mewald, M.2
Oestreich, M.3
-
40
-
-
36148978554
-
Kinetic resolution of 1, 2-diols through highly site-and enantioselective catalytic silylation
-
Zhao, Y., Mitra, A. W., Hoveyda, A. H. & Snapper, M. L. Kinetic resolution of 1, 2-diols through highly site-and enantioselective catalytic silylation. Angew. Chem. Int. Ed. 46, 8471-8474 (2007).
-
(2007)
Angew. Chem. Int. Ed.
, vol.46
, pp. 8471-8474
-
-
Zhao, Y.1
Mitra, A.W.2
Hoveyda, A.H.3
Snapper, M.L.4
-
41
-
-
79961071823
-
Regiodivergent reactions through catalytic enantioselective silylation of chiral diols. Synthesis of sapinofuranone A
-
Rodrigo, J. M., Zhao, Y., Hoveyda, A. H. & Snapper, M. L. Regiodivergent reactions through catalytic enantioselective silylation of chiral diols. Synthesis of sapinofuranone A. Org. Lett. 13, 3778-3781 (2011).
-
(2011)
Org. Lett.
, vol.13
, pp. 3778-3781
-
-
Rodrigo, J.M.1
Zhao, Y.2
Hoveyda, A.H.3
Snapper, M.L.4
-
42
-
-
79961057514
-
Silylation-based kinetic resolution of monofunctional secondary alcohols
-
Sheppard, C. I., Taylor, J. L. & Wiskur, S. L. Silylation-based kinetic resolution of monofunctional secondary alcohols. Org. Lett. 13, 3794-3797 (2011).
-
(2011)
Org. Lett.
, vol.13
, pp. 3794-3797
-
-
Sheppard, C.I.1
Taylor, J.L.2
Wiskur, S.L.3
-
43
-
-
84859553203
-
Catalytic enantioselective dehydrogenative Si-O coupling of oxime ether-functionalized alcohols
-
Weickgenannt, A., Mohr, J. & Oestreich, M. Catalytic enantioselective dehydrogenative Si-O coupling of oxime ether-functionalized alcohols. Tetrahedron 68, 3468-3479 (2012).
-
(2012)
Tetrahedron
, vol.68
, pp. 3468-3479
-
-
Weickgenannt, A.1
Mohr, J.2
Oestreich, M.3
-
44
-
-
0037573574
-
Catalysis through induced intramolecularity: What can be learned by mimicking enzymes with carbonyl compounds that covalently bind substrates?
-
Pascal, R. Catalysis through induced intramolecularity: what can be learned by mimicking enzymes with carbonyl compounds that covalently bind substrates? Eur. J. Org. Chem., 10, 1813-1824 (2003).
-
(2003)
Eur. J. Org. Chem.
, vol.10
, pp. 1813-1824
-
-
Pascal, R.1
-
45
-
-
79961244115
-
Induced intramolecularity: An effective strategy in catalysis
-
Tan, K. L. Induced intramolecularity: an effective strategy in catalysis. ACS Cat. 1, 877-886 (2011).
-
(2011)
ACS Cat.
, vol.1
, pp. 877-886
-
-
Tan, K.L.1
-
46
-
-
84867366871
-
Catalysis through temporary intramolecularity: Mechanistic investigations on aldehyde-catalyzed Cope-type hydroamination lead to the discovery of a more efficient tethering catalyst
-
Guimond, N., MacDonald, M. J., Lemieux, V. & Beauchemin, A. M. Catalysis through temporary intramolecularity: mechanistic investigations on aldehyde-catalyzed Cope-type hydroamination lead to the discovery of a more efficient tethering catalyst. J. Am. Chem. Soc. 134, 16571-16577 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 16571-16577
-
-
Guimond, N.1
MacDonald, M.J.2
Lemieux, V.3
Beauchemin, A.M.4
-
47
-
-
84873632774
-
Highly enantioselective intermolecular hydroamination of allylic amines with chiral aldehydes as tethering catalysts
-
MacDonald, M. J., Hesp, C. R., Schipper, D. J., Pesant, M. & Beauchemin, A. M. Highly enantioselective intermolecular hydroamination of allylic amines with chiral aldehydes as tethering catalysts. Chem. Eur. J. 19, 2597-2601 (2013).
-
(2013)
Chem. Eur. J.
, vol.19
, pp. 2597-2601
-
-
MacDonald, M.J.1
Hesp, C.R.2
Schipper, D.J.3
Pesant, M.4
Beauchemin, A.M.5
-
48
-
-
56549100977
-
Protecting groups for RNA synthesis: An increasing need for selective preparative methods
-
Somoza, A. Protecting groups for RNA synthesis: an increasing need for selective preparative methods. Chem. Soc. Rev. 37, 2668-2675 (2008).
-
(2008)
Chem. Soc. Rev.
, vol.37
, pp. 2668-2675
-
-
Somoza, A.1
-
49
-
-
0030669282
-
Status and prospect of current inotropic agents
-
Repke, K. R. H. & Megges, R. Status and prospect of current inotropic agents. Expert Opin. Ther. Pat. 7, 1297-1306 (1997).
-
(1997)
Expert Opin. Ther. Pat.
, vol.7
, pp. 1297-1306
-
-
Repke, K.R.H.1
Megges, R.2
-
50
-
-
77949567964
-
Resistance to and synthesis of the antibiotic mupirocin
-
Thomas, C. M., Hothersall, J., Willis, C. L. & Simpson, T. J. Resistance to and synthesis of the antibiotic mupirocin. Nature Rev. Microbiol. 8, 281-289 (2010).
-
(2010)
Nature Rev. Microbiol.
, vol.8
, pp. 281-289
-
-
Thomas, C.M.1
Hothersall, J.2
Willis, C.L.3
Simpson, T.J.4
-
51
-
-
0033551859
-
Insights into editing from an Ile-tRNA synthetase structure with tRNA(Ile) and mupirocin
-
Silvian, L. F., Wang, J. & Steitz, T. A. Insights into editing from an Ile-tRNA synthetase structure with tRNA(Ile) and mupirocin. Science 285, 1074-1077 (1999).
-
(1999)
Science
, vol.285
, pp. 1074-1077
-
-
Silvian, L.F.1
Wang, J.2
Steitz, T.A.3
|