Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Zou, Qing Feng ^a   Du, Ji Ke ^a   Zhang, Hua ^b   Wang, Hong Bo ^b   Hu, Ze Dong ^d   Chen, Shu Peng ^b   Du, Yong ^b   Li, Man Zhi ^b   Xie, Dan ^b   Zou, Juan ^c   Sun, Han Dong ^c   Pu, Jian Xin ^c   Zeng, Mu Sheng ^b  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c KUNMING INSTITUTE OF BOTANY   (China)

^d KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase; Longikaurin A (LK A); Nasopharyngeal carcinoma

Indexed keywords

CASPASE; CASPASE 3; CASPASE 9; DITERPENOID; LONGIKAURIN A; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CANCER CELL DESTRUCTION; CANCER INHIBITION; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOUSE; NASOPHARYNX CARCINOMA; NONHUMAN; PROTEIN CLEAVAGE; S PHASE CELL CYCLE CHECKPOINT; UPREGULATION; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; DITERPENES, KAURANE; MICE; MICE, NUDE; NASOPHARYNGEAL NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; S PHASE; SIGNAL TRANSDUCTION; TUMOR STEM CELL ASSAY; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84883079561     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-200     Document Type: Article

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