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Volumn 11, Issue 1, 2013, Pages

Transplantation of human cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells in autism

Author keywords

Autism; Cell transplantation; Cord blood mononuclear cell; Umbilical cord derived mesenchymal stem cell

Indexed keywords

ABERRANT BEHAVIOR CHECKLIST; ARTICLE; AUTISM; CHILD; CHILDHOOD AUTISM RATING SCALE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL ASSESSMENT TOOL; CLINICAL EFFECTIVENESS; CLINICAL GLOBAL IMPRESSION SCALE; CONTROLLED STUDY; CORD BLOOD STEM CELL TRANSPLANTATION; FEMALE; HUMAN; HUMAN CELL; INJECTION; LABORATORY TEST; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MONONUCLEAR CELL; OPEN STUDY; PATIENT SAFETY; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; POSTOPERATIVE COMPLICATION; RATING SCALE; REHABILITATION CARE; SCORING SYSTEM;

EID: 84883077674     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-196     Document Type: Article
Times cited : (134)

References (49)
  • 1
    • 68949159751 scopus 로고    scopus 로고
    • Autism: an emerging 'neuroimmune disorder' in search of therapy
    • 10.1517/14656560903107789, 19640207
    • Theoharides TC, Kempuraj D, Redwood L. Autism: an emerging 'neuroimmune disorder' in search of therapy. Expert Opin Pharmacother 2009, 10(13):2127-2143. 10.1517/14656560903107789, 19640207.
    • (2009) Expert Opin Pharmacother , vol.10 , Issue.13 , pp. 2127-2143
    • Theoharides, T.C.1    Kempuraj, D.2    Redwood, L.3
  • 3
    • 77149144169 scopus 로고    scopus 로고
    • Rising autism rates still pose a mystery
    • 10.1001/jama.2010.113, 20159865
    • Mitka M. Rising autism rates still pose a mystery. JAMA 2010, 303(7):602. 10.1001/jama.2010.113, 20159865.
    • (2010) JAMA , vol.303 , Issue.7 , pp. 602
    • Mitka, M.1
  • 4
    • 33746314832 scopus 로고    scopus 로고
    • Searching for ways out of the autism maze: genetic, epigenetic and environmental clues
    • 10.1016/j.tins.2006.05.010, 16808981
    • Persico AM, Bourgeron T. Searching for ways out of the autism maze: genetic, epigenetic and environmental clues. Trends Neurosci 2006, 29(7):349-358. 10.1016/j.tins.2006.05.010, 16808981.
    • (2006) Trends Neurosci , vol.29 , Issue.7 , pp. 349-358
    • Persico, A.M.1    Bourgeron, T.2
  • 5
    • 77952501114 scopus 로고    scopus 로고
    • Biomarker-guided interventions of clinically relevant conditions associated with autism spectrum disorders and attention deficit hyperactivity disorder
    • Bradstreet JJ, Smith S, Baral M, Rossignol DA. Biomarker-guided interventions of clinically relevant conditions associated with autism spectrum disorders and attention deficit hyperactivity disorder. Altern Med Rev 2010, 15(1):15-32.
    • (2010) Altern Med Rev , vol.15 , Issue.1 , pp. 15-32
    • Bradstreet, J.J.1    Smith, S.2    Baral, M.3    Rossignol, D.A.4
  • 8
    • 56649115703 scopus 로고    scopus 로고
    • Behavioural and developmental interventions for autism spectrum disorder: a clinical systematic review
    • 10.1371/journal.pone.0003755, 2582449, 19015734
    • Ospina MB, Krebs Seida J, Clark B, Karkhaneh M, Hartling L, Tjosvold L, Vandermeer B, Smith V. Behavioural and developmental interventions for autism spectrum disorder: a clinical systematic review. PLoS One 2008, 3(11):e3755. 10.1371/journal.pone.0003755, 2582449, 19015734.
    • (2008) PLoS One , vol.3 , Issue.11
    • Ospina, M.B.1    Krebs Seida, J.2    Clark, B.3    Karkhaneh, M.4    Hartling, L.5    Tjosvold, L.6    Vandermeer, B.7    Smith, V.8
  • 9
    • 4043106484 scopus 로고    scopus 로고
    • Umbilical cord blood cells and brain stroke injury: bringing in fresh blood to address an old problem
    • 484988, 15286794
    • Peterson DA. Umbilical cord blood cells and brain stroke injury: bringing in fresh blood to address an old problem. J Clin Invest 2004, 114(3):312-314. 484988, 15286794.
    • (2004) J Clin Invest , vol.114 , Issue.3 , pp. 312-314
    • Peterson, D.A.1
  • 11
    • 77955105738 scopus 로고    scopus 로고
    • Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions
    • 10.1186/1479-5876-8-75, 2922090, 20682053
    • Yang WZ, Zhang Y, Wu F, Min WP, Minev B, Zhang M, Luo XL, Ramos F, Ichim TE, Riordan NH, Hu X. Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions. J Transl Med 2010, 8:75-80. 10.1186/1479-5876-8-75, 2922090, 20682053.
    • (2010) J Transl Med , vol.8 , pp. 75-80
    • Yang, W.Z.1    Zhang, Y.2    Wu, F.3    Min, W.P.4    Minev, B.5    Zhang, M.6    Luo, X.L.7    Ramos, F.8    Ichim, T.E.9    Riordan, N.H.10    Hu, X.11
  • 14
    • 79952505963 scopus 로고    scopus 로고
    • Immunomodulatory properties and therapeutic application of mesenchymal stem cells
    • 10.1111/j.1365-2249.2011.04327.x, 3087902, 21466544
    • Shi M, Liu ZW, Wang FS. Immunomodulatory properties and therapeutic application of mesenchymal stem cells. Clin Exp Immunol 2011, 164(1):1-8. 10.1111/j.1365-2249.2011.04327.x, 3087902, 21466544.
    • (2011) Clin Exp Immunol , vol.164 , Issue.1 , pp. 1-8
    • Shi, M.1    Liu, Z.W.2    Wang, F.S.3
  • 15
    • 84870465485 scopus 로고
    • Washington (DC): American Psychiatric Association, 4, American Psychiatric Association
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 1994, Washington (DC): American Psychiatric Association, 4, American Psychiatric Association.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 17
    • 11144279423 scopus 로고    scopus 로고
    • Childhood autism rating scale (CARS) and autism behavior checklist (ABC) correspondence and conflicts with DSM-IV criteria in diagnosis of autism
    • 10.1007/s10803-004-5290-2, 15679189
    • Rellini E, Tortolani D, Trillo S, Carbone S, Montecchi F. Childhood autism rating scale (CARS) and autism behavior checklist (ABC) correspondence and conflicts with DSM-IV criteria in diagnosis of autism. J Autism Dev Disord 2004, 34(6):703-708. 10.1007/s10803-004-5290-2, 15679189.
    • (2004) J Autism Dev Disord , vol.34 , Issue.6 , pp. 703-708
    • Rellini, E.1    Tortolani, D.2    Trillo, S.3    Carbone, S.4    Montecchi, F.5
  • 18
    • 0003412410 scopus 로고
    • Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute of Mental Health, Psychopharmacology Research Branch, Division of Extramural Research Programs
    • Guy W. ECDEU Assessment Manual for Psychopharmacology 1976, Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute of Mental Health, Psychopharmacology Research Branch, Division of Extramural Research Programs.
    • (1976) ECDEU Assessment Manual for Psychopharmacology
    • Guy, W.1
  • 19
    • 0022003626 scopus 로고
    • The aberrant behavior checklist: a behavior rating scale for the assessment of treatment effects
    • Aman MG, Singh NN, Stewart AW, Field CJ. The aberrant behavior checklist: a behavior rating scale for the assessment of treatment effects. Am J Ment Defic 1985, 89(5):485-491.
    • (1985) Am J Ment Defic , vol.89 , Issue.5 , pp. 485-491
    • Aman, M.G.1    Singh, N.N.2    Stewart, A.W.3    Field, C.J.4
  • 20
    • 38549091549 scopus 로고    scopus 로고
    • Ziprasidone in adolescents with autism: an open-label pilot study
    • 10.1089/cap.2006.0126, 18315450
    • Malone RP, Delaney MA, Hyman SB, Cater JR. Ziprasidone in adolescents with autism: an open-label pilot study. J Child Adolesc Psychopharmacol 2007, 17(6):779-790. 10.1089/cap.2006.0126, 18315450.
    • (2007) J Child Adolesc Psychopharmacol , vol.17 , Issue.6 , pp. 779-790
    • Malone, R.P.1    Delaney, M.A.2    Hyman, S.B.3    Cater, J.R.4
  • 21
    • 84857190395 scopus 로고    scopus 로고
    • The role of immune dysfunction in the pathophysiology of autism
    • 10.1016/j.bbi.2011.08.007, 3418145, 21906670
    • Onore C, Careaga M, Ashwood P. The role of immune dysfunction in the pathophysiology of autism. Brain Behav Immun 2012, 26(3):383-392. 10.1016/j.bbi.2011.08.007, 3418145, 21906670.
    • (2012) Brain Behav Immun , vol.26 , Issue.3 , pp. 383-392
    • Onore, C.1    Careaga, M.2    Ashwood, P.3
  • 22
    • 11144230769 scopus 로고    scopus 로고
    • Neuroglial activation and neuroinflammation in the brain of patients with autism
    • 10.1002/ana.20315, 15546155
    • Vargas DL, Nascimbene C, Krishnan C, Zimmerman AW, Pardo CA. Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann Neurol 2005, 57(1):67-81. 10.1002/ana.20315, 15546155.
    • (2005) Ann Neurol , vol.57 , Issue.1 , pp. 67-81
    • Vargas, D.L.1    Nascimbene, C.2    Krishnan, C.3    Zimmerman, A.W.4    Pardo, C.A.5
  • 23
    • 78649322790 scopus 로고    scopus 로고
    • Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome
    • Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J. Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain Behav Immun 2011, 5(1):40-45.
    • (2011) Brain Behav Immun , vol.5 , Issue.1 , pp. 40-45
    • Ashwood, P.1    Krakowiak, P.2    Hertz-Picciotto, I.3    Hansen, R.4    Pessah, I.5    Van de Water, J.6
  • 24
    • 79955751714 scopus 로고    scopus 로고
    • In search of cellular immunophenotypes in the blood of children with autism
    • 10.1371/journal.pone.0019299, 3087757, 21573236
    • Ashwood P, Corbett BA, Kantor A, Schulman H, Van de Water J, Amaral DG. In search of cellular immunophenotypes in the blood of children with autism. PLoS One 2011, 6(5):e19299. 10.1371/journal.pone.0019299, 3087757, 21573236.
    • (2011) PLoS One , vol.6 , Issue.5
    • Ashwood, P.1    Corbett, B.A.2    Kantor, A.3    Schulman, H.4    Van de Water, J.5    Amaral, D.G.6
  • 28
    • 4744374906 scopus 로고    scopus 로고
    • Immune response to dietary proteins, gliadin and cerebellar peptides in children with autism
    • 10.1080/10284150400004155, 15526989
    • Vojdani A, O'Bryan T, Green JA, Mccandless J, Woeller KN, Vojdani E, Nourian AA, Cooper EL. Immune response to dietary proteins, gliadin and cerebellar peptides in children with autism. Nutr Neurosci 2004, 7(3):151-161. 10.1080/10284150400004155, 15526989.
    • (2004) Nutr Neurosci , vol.7 , Issue.3 , pp. 151-161
    • Vojdani, A.1    O'Bryan, T.2    Green, J.A.3    Mccandless, J.4    Woeller, K.N.5    Vojdani, E.6    Nourian, A.A.7    Cooper, E.L.8
  • 29
    • 33751581761 scopus 로고    scopus 로고
    • The immune response in autism: a new frontier for autism research
    • 10.1189/jlb.1205707, 16698940
    • Ashwood P, Wills S, Van de Water J. The immune response in autism: a new frontier for autism research. J Leukoc Biol 2006, 80(1):1-15. 10.1189/jlb.1205707, 16698940.
    • (2006) J Leukoc Biol , vol.80 , Issue.1 , pp. 1-15
    • Ashwood, P.1    Wills, S.2    Van de Water, J.3
  • 30
    • 80055119541 scopus 로고    scopus 로고
    • Immunomodulatory activity of mesenchymal stem cells
    • 10.2174/157488811797904353, 21190531
    • Kaplan JM, Youd ME, Lodie TA. Immunomodulatory activity of mesenchymal stem cells. Curr Stem Cell Res Ther 2011, 6(4):297-316. 10.2174/157488811797904353, 21190531.
    • (2011) Curr Stem Cell Res Ther , vol.6 , Issue.4 , pp. 297-316
    • Kaplan, J.M.1    Youd, M.E.2    Lodie, T.A.3
  • 31
    • 35448996504 scopus 로고    scopus 로고
    • Immunomodulation by mesenchymal stem cells and clinical experience
    • 10.1111/j.1365-2796.2007.01844.x, 17949362
    • Le Blanc K, Ringdén O. Immunomodulation by mesenchymal stem cells and clinical experience. J Intern Med 2007, 262(5):509-525. 10.1111/j.1365-2796.2007.01844.x, 17949362.
    • (2007) J Intern Med , vol.262 , Issue.5 , pp. 509-525
    • Le Blanc, K.1    Ringdén, O.2
  • 32
    • 83555172436 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stem cells: cytokines and factors
    • 10.1111/j.1600-0897.2011.01069.x, 21951555
    • Soleymaninejadian E, Pramanik K, Samadian E. Immunomodulatory properties of mesenchymal stem cells: cytokines and factors. Am J Reprod Immunol 2012, 67(1):1-8. 10.1111/j.1600-0897.2011.01069.x, 21951555.
    • (2012) Am J Reprod Immunol , vol.67 , Issue.1 , pp. 1-8
    • Soleymaninejadian, E.1    Pramanik, K.2    Samadian, E.3
  • 33
    • 84862789093 scopus 로고    scopus 로고
    • Umbilical cord mesenchymal stem cells suppress B-cell proliferation and differentiation
    • Che N, Li X, Zhou S, Liu R, Shi D, Lu L, Sun L. Umbilical cord mesenchymal stem cells suppress B-cell proliferation and differentiation. Cell Immunol 2012, 274(1-2):46-53.
    • (2012) Cell Immunol , vol.274 , Issue.1-2 , pp. 46-53
    • Che, N.1    Li, X.2    Zhou, S.3    Liu, R.4    Shi, D.5    Lu, L.6    Sun, L.7
  • 34
    • 78650673843 scopus 로고    scopus 로고
    • Umbilical cord-derived mesenchymal stromal cells modulate monocyte function to suppress T cell proliferation
    • 10.4049/jimmunol.1002239, 20980628
    • Cutler AJ, Limbani V, Girdlestone J, Navarrete CV. Umbilical cord-derived mesenchymal stromal cells modulate monocyte function to suppress T cell proliferation. J Immunol 2010, 185(11):6617-6623. 10.4049/jimmunol.1002239, 20980628.
    • (2010) J Immunol , vol.185 , Issue.11 , pp. 6617-6623
    • Cutler, A.J.1    Limbani, V.2    Girdlestone, J.3    Navarrete, C.V.4
  • 35
    • 77951975599 scopus 로고    scopus 로고
    • Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism
    • 10.1016/j.clim.2010.01.015, 20207200
    • Chen K, Wang D, Du WT, Han ZB, Ren H, Chi Y, Yang SG, Zhu D, Bayard F, Han ZC. Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism. Clin Immunol 2010, 135(3):448-458. 10.1016/j.clim.2010.01.015, 20207200.
    • (2010) Clin Immunol , vol.135 , Issue.3 , pp. 448-458
    • Chen, K.1    Wang, D.2    Du, W.T.3    Han, Z.B.4    Ren, H.5    Chi, Y.6    Yang, S.G.7    Zhu, D.8    Bayard, F.9    Han, Z.C.10
  • 36
    • 77955320722 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation for diffuse alveolar hemorrhage in SLE
    • 10.1038/nrrheum.2010.80, 20517294
    • Liang J, Gu F, Wang H, Hua B, Hou Y, Shi S, Lu L, Sun L. Mesenchymal stem cell transplantation for diffuse alveolar hemorrhage in SLE. Nat Rev Rheumatol 2010, 6(8):486-489. 10.1038/nrrheum.2010.80, 20517294.
    • (2010) Nat Rev Rheumatol , vol.6 , Issue.8 , pp. 486-489
    • Liang, J.1    Gu, F.2    Wang, H.3    Hua, B.4    Hou, Y.5    Shi, S.6    Lu, L.7    Sun, L.8
  • 37
    • 0036038293 scopus 로고    scopus 로고
    • Brain perfusion in autism varies with age
    • 10.1159/000063570, 12571427
    • Wilcox J, Tsuang MT, Ledger E, Algeo J, Schnurr T. Brain perfusion in autism varies with age. Neuropsychobiology 2002, 46(1):13-16. 10.1159/000063570, 12571427.
    • (2002) Neuropsychobiology , vol.46 , Issue.1 , pp. 13-16
    • Wilcox, J.1    Tsuang, M.T.2    Ledger, E.3    Algeo, J.4    Schnurr, T.5
  • 38
    • 60849129127 scopus 로고    scopus 로고
    • Cerebral perfusion abnormalities in children with autism and mental retardation: a segmental quantitative SPECT study
    • Gupta SK, Ratnam BV. Cerebral perfusion abnormalities in children with autism and mental retardation: a segmental quantitative SPECT study. Indian Pediatr 2009, 46(2):161-164.
    • (2009) Indian Pediatr , vol.46 , Issue.2 , pp. 161-164
    • Gupta, S.K.1    Ratnam, B.V.2
  • 39
    • 37349079027 scopus 로고    scopus 로고
    • Regional cerebral blood flow in childhood autism: a SPET study with SPM evaluation
    • 10.1097/MNM.0b013e3282f1bb8e, 18094637
    • Burroni L, Orsi A, Monti L, Hayek Y, Rocchi R, Vattimo AG. Regional cerebral blood flow in childhood autism: a SPET study with SPM evaluation. Nucl Med Commun 2008, 29(2):150-156. 10.1097/MNM.0b013e3282f1bb8e, 18094637.
    • (2008) Nucl Med Commun , vol.29 , Issue.2 , pp. 150-156
    • Burroni, L.1    Orsi, A.2    Monti, L.3    Hayek, Y.4    Rocchi, R.5    Vattimo, A.G.6
  • 43
    • 4644286776 scopus 로고    scopus 로고
    • The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors
    • 10.1182/blood-2003-12-4219, 15213103
    • Hildbrand P, Cirulli V, Prinsen RC, Smith KA, Torbett BE, Salomon DR, Crisa L. The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors. Blood 2004, 104(7):2010-2019. 10.1182/blood-2003-12-4219, 15213103.
    • (2004) Blood , vol.104 , Issue.7 , pp. 2010-2019
    • Hildbrand, P.1    Cirulli, V.2    Prinsen, R.C.3    Smith, K.A.4    Torbett, B.E.5    Salomon, D.R.6    Crisa, L.7
  • 44
    • 0035874498 scopus 로고    scopus 로고
    • Numerous growth factors, cytokines, and chemokines are secreted by human CD34 (+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner
    • 10.1182/blood.V97.10.3075, 11342433
    • Majka M, Janowska-Wieczorek A, Ratajczak J, Ehrenman K, Pietrzkowski Z, Kowalska MA, Gewirtz AM, Emerson SG, Ratajczak MZ. Numerous growth factors, cytokines, and chemokines are secreted by human CD34 (+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood 2001, 97(10):3075-3085. 10.1182/blood.V97.10.3075, 11342433.
    • (2001) Blood , vol.97 , Issue.10 , pp. 3075-3085
    • Majka, M.1    Janowska-Wieczorek, A.2    Ratajczak, J.3    Ehrenman, K.4    Pietrzkowski, Z.5    Kowalska, M.A.6    Gewirtz, A.M.7    Emerson, S.G.8    Ratajczak, M.Z.9
  • 46
    • 33746936122 scopus 로고    scopus 로고
    • Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials
    • Lu LL, Liu YJ, Yang SG, Zhao QJ, Wang X, Gong W, Han ZB, Xu ZS, Lu YX, Liu D, Chen ZZ, Han ZC. Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials. Haematologica 2006, 91(8):1017-1026.
    • (2006) Haematologica , vol.91 , Issue.8 , pp. 1017-1026
    • Lu, L.L.1    Liu, Y.J.2    Yang, S.G.3    Zhao, Q.J.4    Wang, X.5    Gong, W.6    Han, Z.B.7    Xu, Z.S.8    Lu, Y.X.9    Liu, D.10    Chen, Z.Z.11    Han, Z.C.12
  • 47
    • 84858119840 scopus 로고    scopus 로고
    • Autism spectrum disorders: is mesenchymal stem cell personalized therapy the future?
    • 3303614, 22496609
    • Siniscalco D, Sapone A, Cirillo A, Giordano C, Maione S, Antonucci N. Autism spectrum disorders: is mesenchymal stem cell personalized therapy the future?. J Biomed Biotechnol 2012, 2012:480289. 3303614, 22496609.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 480289
    • Siniscalco, D.1    Sapone, A.2    Cirillo, A.3    Giordano, C.4    Maione, S.5    Antonucci, N.6
  • 48
    • 0036682267 scopus 로고    scopus 로고
    • Risperidone in children with autism and serious behavioral problems
    • 10.1056/NEJMoa013171, 12151468
    • Munarriz R, Bennett L, Goldstein I. Risperidone in children with autism and serious behavioral problems. N Engl J Med 2002, 347(5):314-321. 10.1056/NEJMoa013171, 12151468.
    • (2002) N Engl J Med , vol.347 , Issue.5 , pp. 314-321
    • Munarriz, R.1    Bennett, L.2    Goldstein, I.3
  • 49
    • 84883558943 scopus 로고    scopus 로고
    • Reliability and validity of the Chinese version of the aberrant behavior checklist (ABC) in children with autism
    • Ma JH, Guo YQ, Jia MX, Li X, Liu J. Reliability and validity of the Chinese version of the aberrant behavior checklist (ABC) in children with autism. Chin Ment Health J 2011, 25(1):14-19.
    • (2011) Chin Ment Health J , vol.25 , Issue.1 , pp. 14-19
    • Ma, J.H.1    Guo, Y.Q.2    Jia, M.X.3    Li, X.4    Liu, J.5


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