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Volumn 444, Issue 1-2, 2013, Pages 171-180

Translation of viral mRNAs that do not require eIF4E is blocked by the inhibitor 4EGI-1

Author keywords

4EGI 1; EIF4E; IRES inhibitors; IRES translation; Picornavirus translation

Indexed keywords

4EGI 1 INHIBITOR; INITIATION FACTOR 4E; INITIATION FACTOR 4G; MESSENGER RNA; NUCLEIC ACID SYNTHESIS INHIBITOR; UNCLASSIFIED DRUG;

EID: 84882924419     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.06.008     Document Type: Article
Times cited : (6)

References (50)
  • 1
    • 0028787554 scopus 로고
    • Efficient cleavage of p220 by poliovirus 2Apro expression in mammalian cells: effects on vaccinia virus
    • Aldabe R., Feduchi E., Novoa I., Carrasco L. Efficient cleavage of p220 by poliovirus 2Apro expression in mammalian cells: effects on vaccinia virus. Biochem. Biophys. Res. Commun. 1995, 215(3):928-936.
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , Issue.3 , pp. 928-936
    • Aldabe, R.1    Feduchi, E.2    Novoa, I.3    Carrasco, L.4
  • 2
    • 0242661870 scopus 로고    scopus 로고
    • The eukaryotic translation initiation factor 4GI is cleaved by different retroviral proteases
    • Alvarez E., Menendez-Arias L., Carrasco L. The eukaryotic translation initiation factor 4GI is cleaved by different retroviral proteases. J. Virol. 2003, 77(23):12392-12400.
    • (2003) J. Virol. , vol.77 , Issue.23 , pp. 12392-12400
    • Alvarez, E.1    Menendez-Arias, L.2    Carrasco, L.3
  • 3
    • 0029036230 scopus 로고
    • A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cerevisiae
    • Barco A., Carrasco L. A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cerevisiae. EMBO. J. 1995, 14(14):3349-3364.
    • (1995) EMBO. J. , vol.14 , Issue.14 , pp. 3349-3364
    • Barco, A.1    Carrasco, L.2
  • 4
    • 59749095351 scopus 로고    scopus 로고
    • Divergent picornavirus IRES elements
    • Belsham G.J. Divergent picornavirus IRES elements. Virus. Res. 2009, 139(2):183-192.
    • (2009) Virus. Res. , vol.139 , Issue.2 , pp. 183-192
    • Belsham, G.J.1
  • 6
    • 79959345921 scopus 로고    scopus 로고
    • The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases
    • Castello A., Alvarez E., Carrasco L. The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases. J. Biomed. Biotechnol. 2011, 2011:369648.
    • (2011) J. Biomed. Biotechnol. , vol.2011 , pp. 369648
    • Castello, A.1    Alvarez, E.2    Carrasco, L.3
  • 7
    • 29444436204 scopus 로고    scopus 로고
    • Translation of Sindbis virus 26S mRNA does not require intact eukariotic initiation factor 4G
    • Castello A., Sanz M.A., Molina S., Carrasco L. Translation of Sindbis virus 26S mRNA does not require intact eukariotic initiation factor 4G. J. Mol. Biol. 2006, 355(5):942-956.
    • (2006) J. Mol. Biol. , vol.355 , Issue.5 , pp. 942-956
    • Castello, A.1    Sanz, M.A.2    Molina, S.3    Carrasco, L.4
  • 10
    • 0036785522 scopus 로고    scopus 로고
    • Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1
    • Connor J.H., Lyles D.S. Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1. J. Virol. 2002, 76(20):10177-10187.
    • (2002) J. Virol. , vol.76 , Issue.20 , pp. 10177-10187
    • Connor, J.H.1    Lyles, D.S.2
  • 12
    • 0033200316 scopus 로고    scopus 로고
    • Translation driven by an eIF4G core domain in vivo
    • De Gregorio E., Preiss T., Hentze M.W. Translation driven by an eIF4G core domain in vivo. Embo. J. 1999, 18(17):4865-4874.
    • (1999) Embo. J. , vol.18 , Issue.17 , pp. 4865-4874
    • De Gregorio, E.1    Preiss, T.2    Hentze, M.W.3
  • 13
    • 65249165504 scopus 로고    scopus 로고
    • Translation initiation factors are not required for Dicistroviridae IRES function in vivo
    • Deniz N., Lenarcic E.M., Landry D.M., Thompson S.R. Translation initiation factors are not required for Dicistroviridae IRES function in vivo. RNA. 2009, 15(5):932-946.
    • (2009) RNA. , vol.15 , Issue.5 , pp. 932-946
    • Deniz, N.1    Lenarcic, E.M.2    Landry, D.M.3    Thompson, S.R.4
  • 15
    • 77951671938 scopus 로고    scopus 로고
    • The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation
    • Fan S., Li Y., Yue P., Khuri F.R., Sun S.Y. The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation. Neoplasia 2010, 12(4):346-356.
    • (2010) Neoplasia , vol.12 , Issue.4 , pp. 346-356
    • Fan, S.1    Li, Y.2    Yue, P.3    Khuri, F.R.4    Sun, S.Y.5
  • 16
    • 0029417227 scopus 로고
    • Effects of poliovirus 2A(pro) on vaccinia virus gene expression
    • Feduchi E., Aldabe R., Novoa I., Carrasco L. Effects of poliovirus 2A(pro) on vaccinia virus gene expression. Eur. J. Biochem. 1995, 234(3):849-854.
    • (1995) Eur. J. Biochem. , vol.234 , Issue.3 , pp. 849-854
    • Feduchi, E.1    Aldabe, R.2    Novoa, I.3    Carrasco, L.4
  • 17
    • 71849102316 scopus 로고    scopus 로고
    • Bridging IRES elements in mRNAs to the eukaryotic translation apparatus
    • Fitzgerald K.D., Semler B.L. Bridging IRES elements in mRNAs to the eukaryotic translation apparatus. Biochim. Biophys. Acta 2009, 1789(9-10):518-528.
    • (2009) Biochim. Biophys. Acta , vol.1789 , Issue.9-10 , pp. 518-528
    • Fitzgerald, K.D.1    Semler, B.L.2
  • 18
    • 84876339347 scopus 로고    scopus 로고
    • Requirements for eIF4A and eIF2 during translation of Sindbis virus subgenomic mRNA in vertebrate and invertebrate host cells
    • Garcia-Moreno M., Sanz M.A., Pelletier J., Carrasco L. Requirements for eIF4A and eIF2 during translation of Sindbis virus subgenomic mRNA in vertebrate and invertebrate host cells. Cell. Microbiol. 2013, 15(5):823-840.
    • (2013) Cell. Microbiol. , vol.15 , Issue.5 , pp. 823-840
    • Garcia-Moreno, M.1    Sanz, M.A.2    Pelletier, J.3    Carrasco, L.4
  • 19
    • 0032834055 scopus 로고    scopus 로고
    • EIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation
    • Gingras A.C., Raught B., Sonenberg N. eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu. Rev. Biochem. 1999, 68:913-963.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 913-963
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 20
    • 80052742721 scopus 로고    scopus 로고
    • Molecular mechanism of scanning and start codon selection in eukaryotes
    • first page of table of contents
    • Hinnebusch A.G. Molecular mechanism of scanning and start codon selection in eukaryotes. Microbiology and Molecular Biology Reviews 2011, 75(3):434-467. first page of table of contents.
    • (2011) Microbiology and Molecular Biology Reviews , vol.75 , Issue.3 , pp. 434-467
    • Hinnebusch, A.G.1
  • 23
    • 26444583962 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation
    • Hundsdoerfer P., Thoma C., Hentze M.W. Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation. Proc. Natl. Acad. Sci. U. S. A. 2005, 102(38):13421-13426.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , Issue.38 , pp. 13421-13426
    • Hundsdoerfer, P.1    Thoma, C.2    Hentze, M.W.3
  • 24
    • 75149196287 scopus 로고    scopus 로고
    • The mechanism of eukaryotic translation initiation and principles of its regulation
    • Jackson R.J., Hellen C.U., Pestova T.V. The mechanism of eukaryotic translation initiation and principles of its regulation. Nat. Rev. Mol. Cell. Biol. 2010, 11(2):113-127.
    • (2010) Nat. Rev. Mol. Cell. Biol. , vol.11 , Issue.2 , pp. 113-127
    • Jackson, R.J.1    Hellen, C.U.2    Pestova, T.V.3
  • 26
    • 77954373163 scopus 로고    scopus 로고
    • Molecular view of 43 S complex formation and start site selection in eukaryotic translation initiation
    • Lorsch J.R., Dever T.E. Molecular view of 43 S complex formation and start site selection in eukaryotic translation initiation. J Biol Chem. 2010, 285(28):21203-21207.
    • (2010) J Biol Chem. , vol.285 , Issue.28 , pp. 21203-21207
    • Lorsch, J.R.1    Dever, T.E.2
  • 27
    • 38049161643 scopus 로고    scopus 로고
    • Viroporins from RNA viruses induce caspase-dependent apoptosis
    • Madan V., Castello A., Carrasco L. Viroporins from RNA viruses induce caspase-dependent apoptosis. Cell. Microbiol. 2008, 10(2):437-451.
    • (2008) Cell. Microbiol. , vol.10 , Issue.2 , pp. 437-451
    • Madan, V.1    Castello, A.2    Carrasco, L.3
  • 28
    • 0029166687 scopus 로고
    • The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins
    • Mader S., Lee H., Pause A., Sonenberg N. The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins. Mol. Cell. Biol. 1995, 15(9):4990-4997.
    • (1995) Mol. Cell. Biol. , vol.15 , Issue.9 , pp. 4990-4997
    • Mader, S.1    Lee, H.2    Pause, A.3    Sonenberg, N.4
  • 30
    • 0033152072 scopus 로고    scopus 로고
    • Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G
    • Marcotrigiano J., Gingras A.C., Sonenberg N., Burley S.K. Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G. Mol. Cell. 1999, 3(6):707-716.
    • (1999) Mol. Cell. , vol.3 , Issue.6 , pp. 707-716
    • Marcotrigiano, J.1    Gingras, A.C.2    Sonenberg, N.3    Burley, S.K.4
  • 31
    • 78650638897 scopus 로고    scopus 로고
    • Noncytotoxic inhibition of viral infection through eIF4F-independent suppression of translation by 4EGi-1
    • McMahon R., Zaborowska I., Walsh D. Noncytotoxic inhibition of viral infection through eIF4F-independent suppression of translation by 4EGi-1. J. Virol. 2011, 85(2):853-864.
    • (2011) J. Virol. , vol.85 , Issue.2 , pp. 853-864
    • McMahon, R.1    Zaborowska, I.2    Walsh, D.3
  • 34
    • 0033957406 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region
    • Morino S., Imataka H., Svitkin Y.V., Pestova T.V., Sonenberg N. Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region. Mol. Cell. Biol. 2000, 20(2):468-477.
    • (2000) Mol. Cell. Biol. , vol.20 , Issue.2 , pp. 468-477
    • Morino, S.1    Imataka, H.2    Svitkin, Y.V.3    Pestova, T.V.4    Sonenberg, N.5
  • 35
    • 2342614116 scopus 로고    scopus 로고
    • Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen
    • Novac O., Guenier A.S., Pelletier J. Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen. Nucleic Acids Res. 2004, 32(3):902-915.
    • (2004) Nucleic Acids Res. , vol.32 , Issue.3 , pp. 902-915
    • Novac, O.1    Guenier, A.S.2    Pelletier, J.3
  • 38
    • 84871267044 scopus 로고    scopus 로고
    • Translation directed by hepatitis A virus IRES in the absence of active eIF4F complex and eIF2
    • Redondo N., Sanz M.A., Steinberger J., Skern T., Kusov Y., Carrasco L. Translation directed by hepatitis A virus IRES in the absence of active eIF4F complex and eIF2. PLoS One 2012, 7(12):e52065.
    • (2012) PLoS One , vol.7 , Issue.12
    • Redondo, N.1    Sanz, M.A.2    Steinberger, J.3    Skern, T.4    Kusov, Y.5    Carrasco, L.6
  • 39
    • 80053914855 scopus 로고    scopus 로고
    • Translation without eIF2 promoted by poliovirus 2A protease
    • Redondo N., Sanz M.A., Welnowska E., Carrasco L. Translation without eIF2 promoted by poliovirus 2A protease. PLoS One 2011, 6(10):e25699.
    • (2011) PLoS One , vol.6 , Issue.10
    • Redondo, N.1    Sanz, M.A.2    Welnowska, E.3    Carrasco, L.4
  • 40
    • 13444259647 scopus 로고    scopus 로고
    • Regulation of cap-dependent translation by eIF4E inhibitory proteins
    • Richter J.D., Sonenberg N. Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 2005, 433(7025):477-480.
    • (2005) Nature , vol.433 , Issue.7025 , pp. 477-480
    • Richter, J.D.1    Sonenberg, N.2
  • 42
    • 62849120033 scopus 로고    scopus 로고
    • Dual mechanism for the translation of subgenomic mRNA from Sindbis virus in infected and uninfected cells
    • Sanz M.A., Castello A., Ventoso I., Berlanga J.J., Carrasco L. Dual mechanism for the translation of subgenomic mRNA from Sindbis virus in infected and uninfected cells. PLoS One 2009, 4(3):e4772.
    • (2009) PLoS One , vol.4 , Issue.3
    • Sanz, M.A.1    Castello, A.2    Ventoso, I.3    Berlanga, J.J.4    Carrasco, L.5
  • 43
    • 77956178581 scopus 로고    scopus 로고
    • Translation driven by picornavirus IRES is hampered from Sindbis virus replicons: rescue by poliovirus 2A protease
    • Sanz M.A., Welnowska E., Redondo N., Carrasco L. Translation driven by picornavirus IRES is hampered from Sindbis virus replicons: rescue by poliovirus 2A protease. J. Mol. Biol. 2010, 402(1):101-117.
    • (2010) J. Mol. Biol. , vol.402 , Issue.1 , pp. 101-117
    • Sanz, M.A.1    Welnowska, E.2    Redondo, N.3    Carrasco, L.4
  • 44
    • 60149091189 scopus 로고    scopus 로고
    • Regulation of translation initiation in eukaryotes: mechanisms and biological targets
    • Sonenberg N., Hinnebusch A.G. Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell 2009, 136(4):731-745.
    • (2009) Cell , vol.136 , Issue.4 , pp. 731-745
    • Sonenberg, N.1    Hinnebusch, A.G.2
  • 45
    • 84863624560 scopus 로고    scopus 로고
    • 'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)
    • Valasek L.S. 'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs). Curr. Protein Pept. Sci. 2012, 13(4):305-330.
    • (2012) Curr. Protein Pept. Sci. , vol.13 , Issue.4 , pp. 305-330
    • Valasek, L.S.1
  • 46
    • 19244385826 scopus 로고
    • Inhibitors of protein biosynthesis
    • Vazquez D. Inhibitors of protein biosynthesis. Mol. Biol. Biochem. Biophys. 1979, 30(i-x):1-312.
    • (1979) Mol. Biol. Biochem. Biophys. , vol.30 , Issue.1-10 , pp. 1-312
    • Vazquez, D.1
  • 47
    • 0035818541 scopus 로고    scopus 로고
    • HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translation
    • Ventoso I., Blanco R., Perales C., Carrasco L. HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translation. Proc. Natl. Acad. Sci. U. S. A. 2001, 98(23):12966-12971.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.23 , pp. 12966-12971
    • Ventoso, I.1    Blanco, R.2    Perales, C.3    Carrasco, L.4
  • 48
    • 70350712109 scopus 로고    scopus 로고
    • Translation of mRNAs from vesicular stomatitis virus and vaccinia virus is differentially blocked in cells with depletion of eIF4GI and/or eIF4GII
    • Welnowska E., Castello A., Moral P., Carrasco L. Translation of mRNAs from vesicular stomatitis virus and vaccinia virus is differentially blocked in cells with depletion of eIF4GI and/or eIF4GII. J. Mol. Biol. 2009, 394(3):506-521.
    • (2009) J. Mol. Biol. , vol.394 , Issue.3 , pp. 506-521
    • Welnowska, E.1    Castello, A.2    Moral, P.3    Carrasco, L.4
  • 49
    • 79960295860 scopus 로고    scopus 로고
    • Translation of viral mRNA without active eIF2: the case of picornaviruses
    • Welnowska E., Sanz M.A., Redondo N., Carrasco L. Translation of viral mRNA without active eIF2: the case of picornaviruses. PLoS One 2011, 6(7):e22230.
    • (2011) PLoS One , vol.6 , Issue.7
    • Welnowska, E.1    Sanz, M.A.2    Redondo, N.3    Carrasco, L.4
  • 50
    • 0034682720 scopus 로고    scopus 로고
    • Initiation of protein synthesis from the A site of the ribosome
    • Wilson J.E., Pestova T.V., Hellen C.U., Sarnow P. Initiation of protein synthesis from the A site of the ribosome. Cell 2000, 102(4):511-520.
    • (2000) Cell , vol.102 , Issue.4 , pp. 511-520
    • Wilson, J.E.1    Pestova, T.V.2    Hellen, C.U.3    Sarnow, P.4


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