Consequences of exposure to peri-articular injections of micro- and nano-particulate cobalt-chromium alloy

Biomaterials

Volumn 34, Issue 34, 2013, Pages 8564-8580

  Brown, Christopher ^a   Lacharme Lora, Lizeth ^b   Mukonoweshuro, Blessing ^a   Sood, Aman ^b   Newson, Roger B ^c   Fisher, John ^a   Case, C Patrick ^b   Ingham, Eileen ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

DNA damage; Hip replacement; Metal hypersensitivity; Metal on metal; Metallic particles

Indexed keywords

BIOLOGICAL REACTION; COBALT-CHROMIUM ALLOYS; DNA DAMAGES; HIP REPLACEMENTS; IMMUNOLOGICAL EFFECTS; METAL-ON-METAL; METALLIC PARTICLES; MICRON-SIZED PARTICLES;

CHROMIUM ALLOYS; CHROMIUM COMPOUNDS; COBALT; HIP PROSTHESES; JOINTS (ANATOMY); MAMMALS; NANOPARTICLES;

METALS;

ALLOY; CHROMIUM; COBALT; GAMMA INTERFERON; INTERLEUKIN 2; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; DNA DAMAGE; ENZYME LINKED IMMUNOSPOT ASSAY; EXPOSURE; FEMALE; FRONTAL CORTEX; GENOTOXICITY; HIP ARTHROPLASTY; HYPERSENSITIVITY; KNEE; LYMPHOCYTE TRANSFORMATION; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL;

MUS;

DNA DAMAGE; HIP REPLACEMENT; METAL HYPERSENSITIVITY; METAL-ON-METAL; METALLIC PARTICLES;

ANIMALS; BONE MARROW; CHROMIUM; CHROMIUM ALLOYS; CHROMOSOME ABERRATIONS; COBALT; COMET ASSAY; DNA DAMAGE; FEMALE; INJECTIONS, INTRA-ARTICULAR; INTERFERON-GAMMA; INTERLEUKIN-2; KNEE JOINT; METAL NANOPARTICLES; MICE; MICE, INBRED C3H; PARTICLE SIZE; PREFRONTAL CORTEX;

EID: 84882815808     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.07.073     Document Type: Article

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