Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients

International Journal of Cardiology

Volumn 167, Issue 6, 2013, Pages 2875-2881

  Villar, Ana V ^a,b   García, Raquel ^a   Merino, David ^a,b   Llano, Miguel ^a   Cobo, Manuel ^a   Montalvo, Cecilia ^a,b   Martín Durán, Rafael ^a   Hurlé, María A ^a,b   Nistal, J Francisco ^a,b  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Aortic stenosis; MicroRNA; Myocardial fibrosis; Plasma miR 21; TGF signaling

Indexed keywords

BIOLOGICAL MARKER; COLLAGEN; MICRORNA 21; PROTEIN PDCD4; PROTEIN RECK; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADULT; AGED; AORTA STENOSIS; ARTICLE; BLOOD LEVEL; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; ECHOCARDIOGRAPHY; EXTRACELLULAR MATRIX; FEMALE; GENE FUNCTION; GENE OVEREXPRESSION; GENE TARGETING; HEART LEFT VENTRICLE FIBROSIS; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING; LEYDIG CELL; MAJOR CLINICAL STUDY; MALE; MEAN TRANSVALVULAR GRADIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; RNA ANALYSIS; RNA TRANSCRIPTION;

AORTIC STENOSIS; AS; COL; COLLAGEN; ECM; EXTRACELLULAR MATRIX; FIBRONECTIN 1; FN; LEFT VENTRICLE; LV; MICRORNA; MIRNA; MYOCARDIAL FIBROSIS; PDCD4; PHOSPHATASE AND TENSIN HOMOLOG; PLASMA MIR-21; PROGRAMMED CELL DEATH 4; PTEN; RECK; REVERSION-INDUCING-CYSTEINE-RICH PROTEIN WITH KAZAL MOTIFS; SPROUTY HOMOLOG 1; SPRY1; TAK-1; TGF-SS SIGNALING; TGF-Β; TGF-Β ACTIVATED KINASE-1; TIMP3; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSFORMING GROWTH FACTOR-Β;

ADULT; AGED; AGED, 80 AND OVER; AORTIC VALVE STENOSIS; BIOLOGICAL MARKERS; COHORT STUDIES; FEMALE; FIBROSIS; HEART VENTRICLES; HUMANS; MALE; MICRORNAS; MIDDLE AGED; MYOCARDIUM;

EID: 84882771252     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.07.021     Document Type: Article

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