The Akt substrate Girdin is a regulator of insulin signaling in myoblast cells

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 12, 2013, Pages 2803-2811

  Hartung, Angelika ^a   Ordelheide, Anna Maria ^a   Staiger, Harald ^a   Melzer, Martina ^a   Häring, Hans Ulrich ^a   Lammers, Reiner ^a  

^a Department of Internal Medicine IV ^*  (Germany)

Author keywords

Abl; Akt; C2C12; Girdin; Insulin sensitivity

Indexed keywords

ABELSON KINASE; GIRDIN; GLUCOSE; GLYCOGEN; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GLUCOSE BLOOD LEVEL; GLYCOGEN SYNTHESIS; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RESPONSE; INSULIN SENSITIVITY; INTERNALIZATION; MOUSE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 84882760697     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.07.012     Document Type: Article

References (33)

1. Taniguchi C.M., Emanuelli B., Kahn C.R. Critical nodes in signalling pathways: insights into insulin action. Nat. Rev. Mol. Cell Biol. 2006, 7:85-96.
2. White M.F. The insulin signalling system and the IRS proteins. Diabetologia 1997, 40:S2-S17.
3. Leto D., Saltiel A.R. Regulation of glucose transport by insulin: traffic control of GLUT4. Nat. Rev. Mol. Cell Biol. 2012, 13:383-396.
4. Manning B.D., Cantley L.C. AKT/PKB signaling: navigating downstream. Cell 2007, 129:1261-1274.
5. Saltiel A.R., Kahn C.R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001, 414:799-806.
6. Anai M., Shojima N., Katagiri H., Ogihara T., Sakoda H., Onishi Y., Ono H., Fujishiro M., Fukushima Y., Horike N., Viana A., Kikuchi M., Noguchi N., Takahashi S., Takata K., Oka Y., Uchijima Y., Kurihara H., Asano T. A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis. J. Biol. Chem. 2005, 280:18525-18535.
7. Enomoto A., Murakami H., Asai N., Morone N., Watanabe T., Kawai K., Murakumo Y., Usukura J., Kaibuchi K., Takahashi M. Akt/PKB regulates actin organization and cell motility via Girdin/APE. Dev. Cell 2005, 9:389-402.
8. i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles. J. Biol. Chem. 2005, 280:22012-22020.
9. Simpson F., Martin S., Evans T.M., Kerr M., James D.E., Parton R.G., Teasdale R.D., Wicking C. A novel hook-related protein family and the characterization of hook-related protein 1. Traffic 2005, 6:442-458.
10. i with a unique motif that regulates Akt signaling. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:3178-3183.
11. Lin C., Ear J., Pavlova Y., Mittal Y., Kufareva I., Ghassemian M., Abagyan R., Garcia-Marcos M., Ghosh P. Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration. Sci. Signal. 2011, 4:ra64.
12. i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate. Mol. Biol. Cell 2010, 21:2338-2354.
13. Stefan N., Machicao F., Staiger H., Machann J., Schick F., Tschritter O., Spieth C., Weigert C., Fritsche A., Stumvoll M., Häring H.U. Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. Diabetologia 2005, 48:2282-2291.
14. Krützfeldt J., Kausch C., Volk A., Klein H.H., Rett K., Häring H.U., Stumvoll M. Insulin signaling and action in cultured skeletal muscle cells from lean healthy humans with high and low insulin sensitivity. Diabetes 2000, 49:992-998.
15. Chen C., Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell Biol. 1987, 7:2745-2752.
16. Kapp K., Siemens J., Häring H.U., Lammers R. Proteolytic processing of the protein tyrosine phosphatase α extracellular domain is mediated by ADAM17/TACE. Eur. J. Cell Biol. 2012, 91:687-693.
17. Weyrich P., Kapp K., Niederfellner G., Melzer M., Lehmann R., Häring H.U., Lammers R. Partitioning-defective protein 6 regulates insulin-dependent glycogen synthesis via atypical protein kinase C. Mol. Endocrinol. 2004, 18:1287-1300.
18. Nikoulina S.E., Ciaraldi T.P., Mudaliar S., Carter L., Johnson K., Henry R.R. Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle. Diabetes 2002, 51:2190-2198.
19. Genua M., Pandini G., Cassarino M.F., Messina R.L., Frasca F. c-Abl and insulin receptor signalling. Vitam. Horm. 2009, 80:77-105.
20. Parmar S., Smith J., Sassano A., Uddin S., Katsoulidis E., Majchrzak B., Kambhampati S., Eklund E.A., Tallman M.S., Fish E.N., Platanias L.C. Differential regulation of the p70 S6 kinase pathway by interferon α (IFNα) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells. Blood 2005, 106:2436-2443.
21. Jiang P., Enomoto A., Jijiwa M., Kato T., Hasegawa T., Ishida M., Sato T., Asai N., Murakumo Y., Takahashi M. An actin-binding protein Girdin regulates the motility of breast cancer cells. Cancer Res. 2008, 68:1310-1318.
22. i3 triggers cell migration via regulation of GIV. J. Cell Biol. 2008, 182:381-393.
23. Dbouk H.A., Vadas O., Shymanets A., Burke J.E., Salamon R.S., Khalil B.D., Barrett M.O., Waldo G.L., Surve C., Hsueh C., Perisic O., Harteneck C., Shepherd P.R., Harden T.K., Smrcka A.V., Taussig R., Bresnick A.R., Nürnberg B., Williams R.L., Backer J.M. G protein-coupled receptor-mediated activation of p110β by gβγ is required for cellular transformation and invasiveness. Sci. Signal. 2012, 5:ra89.
24. Reinhard C., Fernandez A., Lamb N.J., Thomas G. Nuclear localization of p85s6k: functional requirement for entry into S phase. EMBO J. 1994, 13:1557-1565.
25. Laser M., Kasi V.S., Hamawaki M., Cooper G., Kerr C.M., Kuppuswamy D. Differential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal. J. Biol. Chem. 1998, 273:24610-24619.
26. Kim D., Akcakanat A., Singh G., Sharma C., Meric-Bernstam F. Regulation and localization of ribosomal protein S6 kinase 1 isoforms. Growth Factors 2009, 27:12-21.
27. Jia C.H., Li M., Liu J., Zhao L., Lin J., Lai P.L., Zhou X., Zhang Y., Chen Z.G., Li H.Y., Liu A.L., Yang C.L., Gao T.M., Jiang Y., Bai X.C. IKK-β mediates hydrogen peroxide induced cell death through p85 S6K1. Cell Death Differ. 2012, 20:248-258.
28. Rosner M., Hengstschläger M. Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR. Oncogene 2011, 30:4509-4522.
29. Jaafar R., Zeiller C., Pirola L., Di Grazia A., Naro F., Vidal H., Lefai E., Némoz G. Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes. J. Biol. Chem. 2011, 286:22609-22621.
30. Wiley H.S., Burke P.M. Regulation of receptor tyrosine kinase signaling by endocytic trafficking. Traffic 2001, 2:12-18.
31. Balaji K., Mooser C., Janson C.M., Bliss J.M., Hojjat H., Colicelli J. RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR. J. Cell Sci. 2012, 125:5887-5896.
32. Lee E.K., Gorospe M. Minireview: posttranscriptional regulation of the insulin and insulin-like growth factor systems. Endocrinology 2010, 151:1403-1408.
33. Frasca F., Pandini G., Malaguarnera R., Mandarino A., Messina R.L., Sciacca L., Belfiore A., Vigneri R. Role of c-Abl in directing metabolic versus mitogenic effects in insulin receptor signaling. J. Biol. Chem. 2007, 282:26077-26088.