-
1
-
-
0033595120
-
Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes
-
Cline GW, Petersen KF, Krssak M, Shen J, Hundal RS, Trajanoski Z, Inzucchi S, Dresner A, Rothman DL, Shulman GI: Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes. N Engl J Med 341:240-246, 1999
-
(1999)
N Engl J Med
, vol.341
, pp. 240-246
-
-
Cline, G.W.1
Petersen, K.F.2
Krssak, M.3
Shen, J.4
Hundal, R.S.5
Trajanoski, Z.6
Inzucchi, S.7
Dresner, A.8
Rothman, D.L.9
Shulman, G.I.10
-
2
-
-
0021258643
-
Correlation between muscle glycogen syntliase activity and in vivo insulin action in man
-
Bogardus C, Lillioja S, Stone K, Mott D: Correlation between muscle glycogen syntliase activity and in vivo insulin action in man. J Clin Invest 73:1185-1190, 1984
-
(1984)
J Clin Invest
, vol.73
, pp. 1185-1190
-
-
Bogardus, C.1
Lillioja, S.2
Stone, K.3
Mott, D.4
-
3
-
-
0025860114
-
Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus
-
Damsbo P, Vaag A, Hother-Nielsen O, Beck-Nielsen H: Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 34:239-245, 1991
-
(1991)
Diabetologia
, vol.34
, pp. 239-245
-
-
Damsbo, P.1
Vaag, A.2
Hother-Nielsen, O.3
Beck-Nielsen, H.4
-
4
-
-
0024160877
-
Role of insulin resistance in human disease
-
Reaven GM: Role of insulin resistance in human disease. Diabetes 37:1595-1607, 1988
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
5
-
-
0028079621
-
Role of human skeletal muscle insulin receptor kinase in the in vivo insulin resistance of non-insulin-dependent diabetes mellitus and obesity
-
Nolan JJ, Freidenberg G, Henry R, Reichart D, Olefsky JM: Role of human skeletal muscle insulin receptor kinase in the in vivo insulin resistance of non-insulin-dependent diabetes mellitus and obesity. J Clin Endocrinol Metab 78:471-477, 1994
-
(1994)
J Clin Endocrinol Metab
, vol.78
, pp. 471-477
-
-
Nolan, J.J.1
Freidenberg, G.2
Henry, R.3
Reichart, D.4
Olefsky, J.M.5
-
6
-
-
0024321216
-
A defective intramolecular autoactivation cascade may cause the reduced kinase activity of the skeletal muscle insulin receptor from patients with non-insulin-dependent diabetes mellitus
-
Obermaier-Kusser B, White MF, Pongratz DE, Su Z, Ermel B, Muhlbacher C, Haring HU: A defective intramolecular autoactivation cascade may cause the reduced kinase activity of the skeletal muscle insulin receptor from patients with non-insulin-dependent diabetes mellitus. J Biol Chem 264:9497-9504, 1989
-
(1989)
J Biol Chem
, vol.264
, pp. 9497-9504
-
-
Obermaier-Kusser, B.1
White, M.F.2
Pongratz, D.E.3
Su, Z.4
Ermel, B.5
Muhlbacher, C.6
Haring, H.U.7
-
7
-
-
0028881784
-
Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM
-
Klein HH, Vestergaard H, Kotzke G, Pedersen O: Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM. Diabetes 44:1310-1317, 1995
-
(1995)
Diabetes
, vol.44
, pp. 1310-1317
-
-
Klein, H.H.1
Vestergaard, H.2
Kotzke, G.3
Pedersen, O.4
-
8
-
-
0031057526
-
Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation
-
Bjornholm M, Kawano V, Lehtihet M, Zierath JR: Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetes 46:524-527, 1997
-
(1997)
Diabetes
, vol.46
, pp. 524-527
-
-
Bjornholm, M.1
Kawano, V.2
Lehtihet, M.3
Zierath, J.R.4
-
9
-
-
0032698470
-
Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes
-
Kim YB, Nikoulina SE, Ciaraldi TP, Henry RR, Kalm BB: Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes. J Clin Invest 104:733-741, 1999
-
(1999)
J Clin Invest
, vol.104
, pp. 733-741
-
-
Kim, Y.B.1
Nikoulina, S.E.2
Ciaraldi, T.P.3
Henry, R.R.4
Kalm, B.B.5
-
10
-
-
0031852665
-
Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
-
Krook A, Roth RA, Jiang XJ, Zierath JR, Wallberg-Henriksson H: Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects. Diabetes 47:1281-1286, 1998
-
(1998)
Diabetes
, vol.47
, pp. 1281-1286
-
-
Krook, A.1
Roth, R.A.2
Jiang, X.J.3
Zierath, J.R.4
Wallberg-Henriksson, H.5
-
11
-
-
0032456709
-
Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus: Problems and prospects
-
Ferrannini E: Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus: problems and prospects. Endocrinol Rev 19:477-490, 1998
-
(1998)
Endocrinol Rev
, vol.19
, pp. 477-490
-
-
Ferrannini, E.1
-
12
-
-
0032449219
-
The genetic basis of type 2 diabetes mellitus: Impaired insulin secretion versus impaired insulin sensitivity
-
Gerich JE: The genetic basis of type 2 diabetes mellitus: impaired insulin secretion versus impaired insulin sensitivity. Endocrinol Rev 19:491-503, 1998
-
(1998)
Endocrinol Rev
, vol.19
, pp. 491-503
-
-
Gerich, J.E.1
-
13
-
-
0002872316
-
Empirical risk figures for first-degree relatives of non-insulin-dependent diabetics
-
Kobberling J, Tattersall R, Eds. London, Academic
-
Kobberling J, Tillil H: Empirical risk figures for first-degree relatives of non-insulin-dependent diabetics. In The Genetics of Diabetes Mellitus. Kobberling J, Tattersall R, Eds. London, Academic, 1982, p. 202-209
-
(1982)
The Genetics of Diabetes Mellitus
, pp. 202-209
-
-
Kobberling, J.1
Tillil, H.2
-
14
-
-
0024348996
-
Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellilus
-
Eriksson J, Franssila-Kallunki A, Ekstrand A, Saloranta C, Widen E, Schalin C, Groop L: Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellilus. N Engl J Med 321:337-343, 1989
-
(1989)
N Engl J Med
, vol.321
, pp. 337-343
-
-
Eriksson, J.1
Franssila-Kallunki, A.2
Ekstrand, A.3
Saloranta, C.4
Widen, E.5
Schalin, C.6
Groop, L.7
-
15
-
-
0026575758
-
Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus
-
Vaag A, Henriksen JE, Beck-Nielsen H: Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus. J Clin Invest 89:782-788, 1992
-
(1992)
J Clin Invest
, vol.89
, pp. 782-788
-
-
Vaag, A.1
Henriksen, J.E.2
Beck-Nielsen, H.3
-
16
-
-
0027309410
-
Decreased tyrosine kinase activity in partially purified insulin receptors from muscle of young, non-obese first degree relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus
-
Handberg A, Vaag A, Vinten J, Beck-Nielsen H: Decreased tyrosine kinase activity in partially purified insulin receptors from muscle of young, non-obese first degree relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 36:668-674, 1993
-
(1993)
Diabetologia
, vol.36
, pp. 668-674
-
-
Handberg, A.1
Vaag, A.2
Vinten, J.3
Beck-Nielsen, H.4
-
17
-
-
0032899013
-
Insulin action and secretion in healthy, glucose tolerant first degree relatives of patients with type 2 diabetes mellitus: Influence of body weight
-
Volk A, Renn W, Overkamp D, Mehnert B, Maerker E, Jacob S, Balletshofer B, Haring HU, Rett K: Insulin action and secretion in healthy, glucose tolerant first degree relatives of patients with type 2 diabetes mellitus: influence of body weight. Exp Clin Endocrinol Diabetes 107:140-147, 1999
-
(1999)
Exp Clin Endocrinol Diabetes
, vol.107
, pp. 140-147
-
-
Volk, A.1
Renn, W.2
Overkamp, D.3
Mehnert, B.4
Maerker, E.5
Jacob, S.6
Balletshofer, B.7
Haring, H.U.8
Rett, K.9
-
18
-
-
0342334698
-
Isolation and characterization of human muscle cells
-
Blau HM, Webster C: Isolation and characterization of human muscle cells. Proc Natl Acad Sci U S A 78:5623-5627, 1981
-
(1981)
Proc Natl Acad Sci U S A
, vol.78
, pp. 5623-5627
-
-
Blau, H.M.1
Webster, C.2
-
19
-
-
0029134591
-
Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects: Comparison using human skeletal muscle cell cultures
-
Henry RR, Abrams L, Nikoulina S, Ciaraldi TP: Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects: comparison using human skeletal muscle cell cultures. Diabetes 44:936-946, 1995
-
(1995)
Diabetes
, vol.44
, pp. 936-946
-
-
Henry, R.R.1
Abrams, L.2
Nikoulina, S.3
Ciaraldi, T.P.4
-
20
-
-
0026489975
-
Glucose transport in human skeletal muscle cells in culture: Stimulation by insulin and metformin
-
Sarabia V, Lam L, Burdett K, Leiter LA, Klip A: Glucose transport in human skeletal muscle cells in culture: stimulation by insulin and metformin. J Clin Invest 90:1386-1395, 1992
-
(1992)
J Clin Invest
, vol.90
, pp. 1386-1395
-
-
Sarabia, V.1
Lam, L.2
Burdett, K.3
Leiter, L.A.4
Klip, A.5
-
21
-
-
0029807640
-
Human primary myoblast cell cultures from non-diabetic insulin resistant subjects retain defects in insulin action
-
Thompson DB, Pratley R, Ossowski V: Human primary myoblast cell cultures from non-diabetic insulin resistant subjects retain defects in insulin action. J Clin Invest 98:2346-2350, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 2346-2350
-
-
Thompson, D.B.1
Pratley, R.2
Ossowski, V.3
-
22
-
-
0033007208
-
Insulin receptor antophosphorylation in cultured myoblasts correlates to glucose disposal in Pima Indians
-
Youngren JF, Goldfine ID, Pratley RE: Insulin receptor antophosphorylation in cultured myoblasts correlates to glucose disposal in Pima Indians. Am J Physiol 276:E990-E994, 1999
-
(1999)
Am J Physiol
, vol.276
-
-
Youngren, J.F.1
Goldfine, I.D.2
Pratley, R.E.3
-
23
-
-
0032523817
-
Postabsorptive respiratory quotient and insulin-stimulated glucose storage rate in nondiabetic Pima Indians are related to glycogen synthase fractional activity in cultured myoblasts
-
Mott DM, Pratley RE, Bogardus C: Postabsorptive respiratory quotient and insulin-stimulated glucose storage rate in nondiabetic Pima Indians are related to glycogen synthase fractional activity in cultured myoblasts. J Clin Invest 101:2251-2256, 1998
-
(1998)
J Clin Invest
, vol.101
, pp. 2251-2256
-
-
Mott, D.M.1
Pratley, R.E.2
Bogardus, C.3
-
24
-
-
0029739976
-
Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects: Biochemical and molecular mechanisms
-
Henry RR, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Park KS, Nikoulina SE: Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects: biochemical and molecular mechanisms. J Clinn Invest 98:1231-1236, 1996
-
(1996)
J Clinn Invest
, vol.98
, pp. 1231-1236
-
-
Henry, R.R.1
Ciaraldi, T.P.2
Abrams-Carter, L.3
Mudaliar, S.4
Park, K.S.5
Nikoulina, S.E.6
-
25
-
-
0028799952
-
Glucose transport in cultured human skeletal muscle cells: Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects
-
Ciaraldi TP, Abrams L, Nikoulina S, Mudaliar S, Henry RR: Glucose transport in cultured human skeletal muscle cells: regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects. J Clin Invest 96:2820-2827, 1995
-
(1995)
J Clin Invest
, vol.96
, pp. 2820-2827
-
-
Ciaraldi, T.P.1
Abrams, L.2
Nikoulina, S.3
Mudaliar, S.4
Henry, R.R.5
-
26
-
-
0030895726
-
Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: Evidence for a P13-kinase mediated effect
-
Berti L, Kellerer M, Capp E, Haring HU: Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect. Diabetologia 40:606-609, 1997
-
(1997)
Diabetologia
, vol.40
, pp. 606-609
-
-
Berti, L.1
Kellerer, M.2
Capp, E.3
Haring, H.U.4
-
27
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
28
-
-
0031002113
-
Insulin stimulation of human adipocytes activates the kinase of only a fraction of the insulin receptors
-
Klein HH, Kowalewski B, Drenckhan M, Fehm HL: Insulin stimulation of human adipocytes activates the kinase of only a fraction of the insulin receptors. Am J Physiol 272:E576-E583, 1997
-
(1997)
Am J Physiol
, vol.272
-
-
Klein, H.H.1
Kowalewski, B.2
Drenckhan, M.3
Fehm, H.L.4
-
29
-
-
0032896443
-
Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation
-
Klein HH, Muller R, Vestergaard H, Pedersen O: Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation. Diabetologia 42:245-249, 1999
-
(1999)
Diabetologia
, vol.42
, pp. 245-249
-
-
Klein, H.H.1
Muller, R.2
Vestergaard, H.3
Pedersen, O.4
-
30
-
-
0033564888
-
Microtiter well assays for protein tyrosine phosphatase activities directed against phosphorylated insulin receptor or insulin receptor substrate-1
-
Krützfeldt J, Grunweller A, Raasch W, Drenckhan M, Klein HH: Microtiter well assays for protein tyrosine phosphatase activities directed against phosphorylated insulin receptor or insulin receptor substrate-1. Anal Biochem 271:97-99, 1999
-
(1999)
Anal Biochem
, vol.271
, pp. 97-99
-
-
Krützfeldt, J.1
Grunweller, A.2
Raasch, W.3
Drenckhan, M.4
Klein, H.H.5
-
31
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi DR, Andjelkovic M, Caudwell B, Cron N, Morrice N, Cohen P, Hemmings BA: Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15:6541-6551, 1996
-
(1996)
EMBO J
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, N.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
32
-
-
0014949207
-
The cleavage of T4-phage
-
Laemmli UK: The cleavage of T4-phage. Nature 227:680-685, 1970
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
33
-
-
0032509202
-
Stimulation of IRS-1-associated phosphatidylinositol 3-kinase and Akt/protein kinase B but not glucose transport by beta1-integrin signaling in rat adipocytes
-
Guilherme A, Czech MP: Stimulation of IRS-1-associated phosphatidylinositol 3-kinase and Akt/protein kinase B but not glucose transport by beta1-integrin signaling in rat adipocytes. J Biol Chem 273:33119-33122, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 33119-33122
-
-
Guilherme, A.1
Czech, M.P.2
-
34
-
-
0028147131
-
Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man
-
Del Prato S, Leonetti F, Simonson DC, Sheehan P, Matsuda M, DeFronzo RA: Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man. Diabetologia 37:1025-1035, 1994
-
(1994)
Diabetologia
, vol.37
, pp. 1025-1035
-
-
Del Prato, S.1
Leonetti, F.2
Simonson, D.C.3
Sheehan, P.4
Matsuda, M.5
DeFronzo, R.A.6
-
35
-
-
0032765395
-
Glucose turnover and adipose tissue lipolysis are insulin-resistant in healthy relatives of type 2 diabetes patients: Is cellular insulin resistance a secondary phenomenon?
-
Eriksson JW, Smith U, Waagstein F, Wysocki M, Jansson PA: Glucose turnover and adipose tissue lipolysis are insulin-resistant in healthy relatives of type 2 diabetes patients: is cellular insulin resistance a secondary phenomenon? Diabetes 48:1572-1578, 1999
-
(1999)
Diabetes
, vol.48
, pp. 1572-1578
-
-
Eriksson, J.W.1
Smith, U.2
Waagstein, F.3
Wysocki, M.4
Jansson, P.A.5
-
36
-
-
7844248273
-
Troglitazone regulation of glucose metabolism in human skeletal muscle cultures from obese type II diabetic subjects
-
Park KS, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Nikoulina SE, Henry RR: Troglitazone regulation of glucose metabolism in human skeletal muscle cultures from obese type II diabetic subjects. J Clin Endocrinol Metab 83:1636-1643, 1998
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 1636-1643
-
-
Park, K.S.1
Ciaraldi, T.P.2
Abrams-Carter, L.3
Mudaliar, S.4
Nikoulina, S.E.5
Henry, R.R.6
-
37
-
-
0030905313
-
Regulation of glycogen synthase activity in cultured skeletal muscle cells from subjects with type II diabetes: Role of chronic hyperinsulinemia and hyperglycemia
-
Nikoulina SE, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Park KS, Henry RR: Regulation of glycogen synthase activity in cultured skeletal muscle cells from subjects with type II diabetes: role of chronic hyperinsulinemia and hyperglycemia. Diabetes 46:1017-1024, 1997
-
(1997)
Diabetes
, vol.46
, pp. 1017-1024
-
-
Nikoulina, S.E.1
Ciaraldi, T.P.2
Abrams-Carter, L.3
Mudaliar, S.4
Park, K.S.5
Henry, R.R.6
-
38
-
-
0025991864
-
In vivo stimulation of the insulin receptor kinase in human skeletal muscle: Correlation with insulin-stimulated glucose disposal during euglycemic clamp studies
-
Freidenberg GR, Suter SL, Henry RR, Reichart D, Olefsky JM: In vivo stimulation of the insulin receptor kinase in human skeletal muscle: correlation with insulin-stimulated glucose disposal during euglycemic clamp studies. J Clin Invest 87:2222-2229, 1991
-
(1991)
J Clin Invest
, vol.87
, pp. 2222-2229
-
-
Freidenberg, G.R.1
Suter, S.L.2
Henry, R.R.3
Reichart, D.4
Olefsky, J.M.5
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