A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity

Analytical Biochemistry

Volumn 441, Issue 2, 2013, Pages 152-161

  Poras, Hervé ^a   Duquesnoy, Sophie ^a   Fournié Zaluski, Marie Claude ^a   Ratinaud Giraud, Céline ^a   Roques, Bernard P ^a   Ouimet, Tanja ^a  

^a Pharmaleads   (France)

Author keywords

Aminopeptidase; In vivo enzyme assay; LTA4 hydrolase; Specific inhibitor; Specific substrate

Indexed keywords

HYDROLASES;

AMINO PEPTIDASE; ENZYME ASSAYS; LTA4 HYDROLASE; SPECIFIC INHIBITORS; SPECIFIC SUBSTRATES;

SUBSTRATES;

(4 BENZOYL)PHENYLALANYL BETA NAPHTHYLAMIDE; AMINO ACID; AMINOPEPTIDASE; LEUKOTRIENE A4 HYDROLASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; FLUOROMETRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SENSITIVITY AND SPECIFICITY;

AMINOPEPTIDASE; IN VIVO ENZYME ASSAY; LTA4 HYDROLASE; SPECIFIC INHIBITOR; SPECIFIC SUBSTRATE;

ANIMALS; ENZYME ASSAYS; ENZYME INHIBITORS; EPOXIDE HYDROLASES; HUMANS; MALE; MICE; MOLECULAR DOCKING SIMULATION; NAPHTHALENES; PEPTIDES; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY;

EID: 84882750148     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.06.016     Document Type: Article

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