Myelin and axon abnormalities in schizophrenia measured with magnetic resonance imaging techniques

Biological Psychiatry

Volumn 74, Issue 6, 2013, Pages 451-457

  Du, Fei ^a   Cooper, Alissa J ^a   Thida, Thida ^a   Shinn, Ann K ^a   Cohen, Bruce M ^a   Öngür, Dost ^a  

^a MCLEAN HOSPITAL   (United States)

Author keywords

Diffusion; frontal lobe; magnetic resonance spectroscopy; magnetization transfer ratio; N acetylaspartate; white matter

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; CHLORPROMAZINE; LITHIUM; MYELIN; N ACETYLASPARTIC ACID; NEUROLEPTIC AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DIFFUSION TENSOR IMAGING; FEMALE; HUMAN; MALE; MYELIN SHEATH; NERVE FIBER; POSITIVE AND NEGATIVE SYNDROME SCALE; PREFRONTAL CORTEX; PRIORITY JOURNAL; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; WHITE MATTER;

EID: 84882702912     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.03.003     Document Type: Article

References (61)

1. K. Sim, G.L. Yang, D. Loh, L.Y. Poon, Y.Y. Sitoh, and S. Verma White matter abnormalities and neurocognitive deficits associated with the passivity phenomenon in schizophrenia: A diffusion tensor imaging study Psychiatry Res 172 2009 121 127
2. S.S. Shergill, R.A. Kanaan, X.A. Chitnis, O. O'Daly, D.K. Jones, and S. Frangou A diffusion tensor imaging study of fasciculi in schizophrenia Am J Psychiatry 164 2007 467 473
3. K.H. Karlsgodt, T.G. van Erp, R.A. Poldrack, C.E. Bearden, K.H. Nuechterlein, and T.D. Cannon Diffusion tensor imaging of the superior longitudinal fasciculus and working memory in recent-onset schizophrenia Biol Psychiatry 63 2008 512 518
4. M. Kubicki, C.F. Westin, P.G. Nestor, C.G. Wible, M. Frumin, and S.E. Maier Cingulate fasciculus integrity disruption in schizophrenia: A magnetic resonance diffusion tensor imaging study Biol Psychiatry 54 2003 1171 1180
5. N. Rusch, I. Spoletini, M. Wilke, P. Bria, M. Di Paola, and F. Di Iulio Prefrontal-thalamic-cerebellar gray matter networks and executive functioning in schizophrenia Schizophr Res 93 2007 79 89
6. K. Takei, H. Yamasue, O. Abe, H. Yamada, H. Inoue, and M. Suga Structural disruption of the dorsal cingulum bundle is associated with impaired Stroop performance in patients with schizophrenia Schizophr Res 114 2009 119 127
7. P.G. Nestor, M. Kubicki, R.J. Gurrera, M. Niznikiewicz, M. Frumin, and R.W. McCarley Neuropsychological correlates of diffusion tensor imaging in schizophrenia Neuropsychology 18 2004 629 637
8. P.G. Nestor, M. Kubicki, M. Niznikiewicz, R.J. Gurrera, R.W. McCarley, and M.E. Shenton Neuropsychological disturbance in schizophrenia: A diffusion tensor imaging study Neuropsychology 22 2008 246 254
9. I. Spoletini, A. Cherubini, M. Di Paola, G. Banfi, N. Rusch, and G. Martinotti Reduced fronto-temporal connectivity is associated with frontal gray matter density reduction and neuropsychological deficit in schizophrenia Schizophr Res 108 2009 57 68
10. R.G. Schlosser, I. Nenadic, G. Wagner, D. Gullmar, K. von Consbruch, and S. Kohler White matter abnormalities and brain activation in schizophrenia: A combined DTI and fMRI study Schizophr Res 89 2007 1 11
11. P. Williamson Are anticorrelated networks in the brain relevant to schizophrenia? Schizophr Bull 33 2007 994 1003
12. A.G. Garrity, G.D. Pearlson, K. McKiernan, D. Lloyd, K.A. Kiehl, and V.D. Calhoun Aberrant "default mode" functional connectivity in schizophrenia Am J Psychiatry 164 2007 450 457
13. S. Whitfield-Gabrieli, H.W. Thermenos, S. Milanovic, M.T. Tsuang, S.V. Faraone, and R.W. McCarley Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia Proc Natl Acad Sci U S A 106 2009 1279 1284
14. D. Tkachev, M.L. Mimmack, M.M. Ryan, M. Wayland, T. Freeman, and P.B. Jones Oligodendrocyte dysfunction in schizophrenia and bipolar disorder Lancet 362 2003 798 805
15. K.E. Stephan, K.J. Friston, and C.D. Frith Dysconnection in schizophrenia: From abnormal synaptic plasticity to failures of self-monitoring Schizophr Bull 35 2009 509 527
16. T. Paus, M. Keshavan, and J.N. Giedd Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci 9 2008 947 957
17. M. Kubicki, R. McCarley, C.F. Westin, H.J. Park, S. Maier, and R. Kikinis A review of diffusion tensor imaging studies in schizophrenia J Psychiatr Res 41 2007 15 30
18. T.J. Whitford, J.M. Ford, D.H. Mathalon, M. Kubicki, and M.E. Shenton Schizophrenia, myelination, and delayed corollary discharges: A hypothesis Schizophr Bull 38 2012 486 494
19. A.L. Alexander, J.E. Lee, M. Lazar, and A.S. Field Diffusion tensor imaging of the brain Neurotherapeutics 4 2007 316 329
20. M. Kubicki, H. Park, C.F. Westin, P.G. Nestor, R.V. Mulkern, and S.E. Maier DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity Neuroimage 26 2005 1109 1118
21. G. Price, M. Cercignani, E.M. Chu, T.R. Barnes, G.J. Barker, and E.M. Joyce Brain pathology in first-episode psychosis: magnetization transfer imaging provides additional information to MRI measurements of volume loss Neuroimage 49 2010 185 192
22. R.C. Mandl, H.G. Schnack, J. Luigjes, M.P. van den Heuvel, W. Cahn, R.S. Kahn, and H.E. Hulshoff Pol Tract-based analysis of magnetization transfer ratio and diffusion tensor imaging of the frontal and frontotemporal connections in schizophrenia Schizophr Bull 36 2010 778 787
23. G. Tsai, and J.T. Coyle N-acetylaspartate in neuropsychiatric disorders Prog Neurobiol 46 1995 531 540
24. K.O. Lim, E. Adalsteinsson, D. Spielman, E.V. Sullivan, M.J. Rosenbloom, and A. Pfefferbaum Proton magnetic resonance spectroscopic imaging of cortical gray and white matter in schizophrenia Arch Gen Psychiatry 55 1998 346 352
25. D. Ongur, A.P. Prescot, J.E. Jensen, E.D. Rouse, B.M. Cohen, and P.F. Renshaw T2 relaxation time abnormalities in bipolar disorder and schizophrenia Magn Reson Med 63 2010 1 8
26. J.J. Ackerman, and J.J. Neil The use of MR-detectable reporter molecules and ions to evaluate diffusion in normal and ischemic brain NMR Biomed 23 2010 725 733
27. J. Upadhyay, K. Hallock, M. Ducros, D.S. Kim, and I. Ronen Diffusion tensor spectroscopy and imaging of the arcuate fasciculus Neuroimage 39 2008 1 9
28. M. Harada, M. Uno, F. Hong, S. Hisaoka, H. Nishitani, and T. Matsuda Diffusion-weighted in vivo localized proton MR spectroscopy of human cerebral ischemia and tumor NMR Biomed 15 2002 69 74
29. O. Abe, T. Okubo, N. Hayashi, N. Saito, N. Iriguchi, and I. Shirouzu Temporal changes of the apparent diffusion coefficients of water and metabolites in rats with hemispheric infarction: Experimental study of transhemispheric diaschisis in the contralateral hemisphere at 7 tesla J Cereb Blood Flow Metab 20 2000 726 735
30. W. Dreher, E. Busch, and D. Leibfritz Changes in apparent diffusion coefficients of metabolites in rat brain after middle cerebral artery occlusion measured by proton magnetic resonance spectroscopy Magn Reson Med 45 2001 383 389
31. Z. Liu, X. Liu, L. Hui, D. Zhao, X. Wang, and S. Xie The appearance of ADCs in the non-affected areas of the patients with MELAS Neuroradiology 53 2011 227 232
32. T. Chomiak, and B. Hu What is the optimal value of the g-ratio for myelinated fibers in the rat CNS? A theoretical approach PLoS One 4 2009 e7754
33. E.R. Kandel, J.H. Schwartz, and T.M. Jessell Principles of Neural Science 3rd ed 1991 Elsevier New York
34. T. Paus, and R. Toro Could sex differences in white matter be explained by g ratio? Front Neuroanat 3 2009 14
35. K.A. Nave Myelination and the trophic support of long axons Nat Rev Neurosci 11 2010 275 283
36. N.A. Uranova, V.M. Vostrikov, O.V. Vikhreva, I.S. Zimina, N.S. Kolomeets, and D.D. Orlovskaya The role of oligodendrocyte pathology in schizophrenia Int J Neuropsychopharmacol 10 2007 537 545
37. S.W. Flynn, D.J. Lang, A.L. Mackay, V. Goghari, I.M. Vavasour, and K.P. Whittall Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins Mol Psychiatry 8 2003 811 820
38. R.E. McCullumsmith, D. Gupta, M. Beneyto, E. Kreger, V. Haroutunian, and K.L. Davis Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia Schizophr Res 90 2007 15 27
39. Y. Hakak, J.R. Walker, C. Li, W.H. Wong, K.L. Davis, and J.D. Buxbaum Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia Proc Natl Acad Sci U S A 98 2001 4746 4751
40. S. Budel, T. Padukkavidana, B.P. Liu, Z. Feng, F. Hu, and S. Johnson Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth J Neurosci 28 2008 13161 13172
41. H.G. Bernstein, J. Steiner, and B. Bogerts Glial cells in schizophrenia: Pathophysiological significance and possible consequences for therapy Expert Rev Neurother 9 2009 1059 1071
42. R.A. de Graaf, Y. Luo, M. Garwood, and K. Nicolay B1-insensitive, single-shot localization and water suppression J Magn Reson B 113 1996 35 45
43. Chen W, Luo Y, Merkle H, Zhu X-H, Adriany G, Garwood M, et al. (1995): Low-power, B1-insensitive, frequency-selective saturation pulse for use of water suppression and saturation transfer in NMR. SMR, 3rd Annual Meeting. Nice, France: Society for Magnetic Resonance, 1016.
44. H.E. Kan, A. Techawiboonwong, M.J. van Osch, M.J. Versluis, D.K. Deelchand, and P.G. Henry Differences in apparent diffusion coefficients of brain metabolites between grey and white matter in the human brain measured at 7 T Magn Reson Med 67 2012 1203 1209
45. I. Tkac, Z. Starcuk, I.Y. Choi, and R. Gruetter In vivo 1H NMR spectroscopy of rat brain at 1 ms echo time Magn Reson Med 41 1999 649 656
46. J.K. Choi, A. Dedeoglu, and B.G. Jenkins Application of MRS to mouse models of neurodegenerative illness NMR Biomed 20 2007 216 237
47. J. Camchong, K.O. Lim, S.R. Sponheim, and A.W. Macdonald Frontal white matter integrity as an endophenotype for schizophrenia: Diffusion tensor imaging in monozygotic twins and patients' nonpsychotic relatives Front Hum Neurosci 3 2009 35
48. J. Valette, M. Guillermier, L. Besret, P. Hantraye, G. Bloch, and V. Lebon Isoflurane strongly affects the diffusion of intracellular metabolites, as shown by 1H nuclear magnetic resonance spectroscopy of the monkey brain J Cereb Blood Flow Metab 27 2007 588 596
49. G. Chakraborty, P. Mekala, D. Yahya, G. Wu, and R.W. Ledeen Intraneuronal N-acetylaspartate supplies acetyl groups for myelin lipid synthesis: Evidence for myelin-associated aspartoacylase J Neurochem 78 2001 736 745
50. D. Ben-Shachar, and D. Laifenfeld Mitochondria, synaptic plasticity, and schizophrenia Int Rev Neurobiol 59 2004 273 296
51. F. Du, A. Cooper, B.M. Cohen, P.F. Renshaw, and D. Ongur Water and metabolite transverse T2 relaxation time abnormalities in the white matter in schizophrenia Schizophr Res 137 2012 241 245
52. A.A. Maudsley, C. Domenig, V. Govind, A. Darkazanli, C. Studholme, and K. Arheart Mapping of brain metabolite distributions by volumetric proton MR spectroscopic imaging (MRSI) Magn Reson Med 61 2009 548 559
53. S. Posse, R. Otazo, A. Caprihan, J. Bustillo, H. Chen, and P.G. Henry Proton echo-planar spectroscopic imaging of J-coupled resonances in human brain at 3 and 4 Tesla Magn Reson Med 58 2007 236 244
54. J.T. Coyle The nagging question of the function of N- acetylaspartylglutamate Neurobiol Dis 4 1997 231 238
55. P.J. Pouwels, and J. Frahm Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS NMR Biomed 10 1997 73 78
56. V. Govindaraju, K. Young, and A.A. Maudsley Proton NMR chemical shifts and coupling constants for brain metabolites NMR in Biomedicine 13 2000 129 153
57. C. Laule, I.M. Vavasour, S.H. Kolind, D.K. Li, T.L. Traboulsee, and G.R. Moore Magnetic resonance imaging of myelin Neurotherapeutics 4 2007 460 484
58. A MacKay, C Laule, I Vavasour, T Bjarnason, S Kolind, and B Madler Insights into brain microstructure from the T2 distribution Magn Reson Imaging 24 2006 515 525
59. J.I. Friedman, C. Tang, D. Carpenter, M. Buchsbaum, J. Schmeidler, and L. Flanagan Diffusion tensor imaging findings in first-episode and chronic schizophrenia patients Am J Psychiatry 165 2008 1024 1032
60. Heng S, Song AW, Sim K (2010): White matter abnormalities in bipolar disorder: Insights from diffusion tensor imaging studies. J Neural Transm 117:639-654.
61. T. White, M. Nelson, and K.O. Lim Diffusion tensor imaging in psychiatric disorders Top Magn Reson Imaging 19 2008 97 109