Effect of amino acids supply in reduced crude protein diets on performance, efficiency of mammary uptake, and transporter gene expression in lactating sows

Journal of Animal Science

Volumn 90, Issue 9, 2012, Pages 3088-3100

  Manjarin, R ^a   Zamora, V ^b   Wu, G ^c   Steibel, J P ^a   Kirkwood, R N ^a   Taylor, N P ^a   Wils Plotz, E ^a   Trifilo, K ^a   Trottier, N L ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Colegio de Postgraduados ^*  (Mexico)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Amino acid; Efficiency; Gene; Lactation; Sow; Transporter

Indexed keywords

AMINO ACID; CARRIER PROTEIN; MESSENGER RNA;

ANIMAL; ARTICLE; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LACTATION; METABOLISM; PHYSIOLOGY; PROTEIN INTAKE; UDDER; VASCULARIZATION;

AMINO ACIDS; ANIMALS; CARRIER PROTEINS; DIETARY PROTEINS; FEMALE; GENE EXPRESSION REGULATION; LACTATION; MAMMARY GLANDS, ANIMAL; RNA, MESSENGER;

EID: 84882698858     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2011-4338     Document Type: Article

References (50)

1. Ball, R. O., J. L. Atkinson, and H. S. Bayley. 1986. Proline as an essential amino acid for the young pig. Br J Nutr 55:659-668.
2. Bequette, B. J., J. A. Metcalf, D. Wray-Cahen, F. R. Backwell, J. D. Sutton, M. A. Lomax, J. C. MacRae, and G. E. Lobley. 1996. Leucine and protein metabolism in the lactating dairy cow mammary gland: Responses to supplemental dietary crude protein intake. J. Dairy Res. 63:209-222.
3. Bionaz, M., and J. J. Loor. 2007. Identification of reference genes for quantitative real-time PCR in the bovine mammary gland during the lactation cycle. Physiol. Genomics 29:312-319.
4. Broër, S. 2008. Amino acid transport across mammalian intestinal and renal epithelia. Physiol. Rev. 88:249-286.
5. Burgos, S. A., M. Dai, and J. P. Cant. 2010. Nutrient availability and lactogenic hormones regulate mammary protein synthesis through the mammalian target of rapamycin signaling pathway. J. Dairy Sci. 93:153-161.
6. Calvert, D. T., and D. B. Shennan. 1996. Evidence for an interaction between cationic and neutral amino acids at the blood-facing aspect of the lactating rat mammary epithelium. J. Dairy Res. 63:25-33.
7. Dourmad, J. Y., J. Noblet, and M. Etienne. 1998. Effect of protein and lysine supply on performance, nitrogen balance, and body composition changes of sows during lactation. J. Anim. Sci. 76:542-550.
8. Guan, X., B. J. Bequette, G. Calder, P. K. Ku, K. N. Ames, and N. L. Trottier. 2002. Amino acid availability affects amino acid flux and protein metabolism in the porcine mammary gland. J. Nutr. 132:1224-1234.
9. Guan, X., J. E. Pettigrew, P. K. Ku, K. N. Ames, B. J. Bequette, and N. L. Trottier. 2004. Dietary protein concentration affects plasma arteriovenous difference of amino acids across the porcine mammary gland. J. Anim. Sci. 82:2953-2963.
10. Hayashi, A. A., K. Nones, N. C. Roy, W. C. McNabb, D. S. Mackenzie, D. Pacheco, and S. McCoard. 2009. Initiation and elongation steps of mRNA translation are involved in the increase in milk protein yield caused by growth hormone administration during lactation. J. Dairy Sci. 92:1889-1899.
11. Hayashi, A. A., and C. G. Proud. 2007. The rapid activation of protein synthesis by growth hormone requires signaling through m TOR. Am. J. Physiol. Endocrinol. Metab. 292:E1647-E1655.
12. Herman, M. A., P. She, O. D. Peroni, C. J. Lynch, and B. B. Kahn. 2010. Adipose tissue branched-chain amino acid (BCAA) metabolism modulates circulating BCAA levels. J. Biol. Chem. 285:11348-11356.
13. Hundal, H. S, and P. M. Taylor. 2009. Amino acid transceptors: Gate keepers of nutrient exchange and regulators of nutrient signaling. Am. J. Physiol. Endocrinol. Metab. 296:E603-E613.
14. Kim, S. W., W. L. Hurley, I. K. Han, and R. A. Easter. 1999. Changes in tissue composition associated with mammary gland growth during lactation in sows. J. Anim. Sci. 77:2510-2516.
15. Kim, S. W., and G. Wu. 2009. Regulatory role for amino acids in mammary gland growth and milk synthesis. Amino Acids 37:89-95.
16. Kimball, S. R., and L. S. Jefferson. 2006. New functions for amino acids: Effects on gene transcription and translation. Am. J. Clin. Nutr. 83:500S-507S.
17. Kirkwood, R. N., J. Pérez-Laspiur, N. K. Ames, J. B. Moore, A. Cegielski, and N. L. Trottier. 2007. Mammary gland biopsy does not affect lactation performance in sows. Can. J. Anim. Sci. 87:281-284.
18. Labarca, C., and K. Paigen. 1980. A simple, rapid and sensitive DNA assay procedure. Anal. Biochem. 102:344-352.
19. Larionov, A., A. Krause, and W. Miller. 2005. A standard curve based method for relative real time PCR data processing. BMC Bioinformatics 6:62-77.
20. Li, P., D. A. Knabe, S. W. Kim, C. J. Lynch, S. M. Hutson, and G. Wu. 2009. Lactating porcine mammary tissue catabolizes branched-chain amino acids for glutamine and aspartate synthesis. J. Nutr. 139:1502-1509.
21. Li, X. L., R. Rezaei, P. Li, and G. Wu. 2011. Composition of amino acids in feed ingredients for animal diets. Amino Acids 40:1159-1168.
22. Manjarín, R., J. P. Steibel, V. Zamora, N. Amin, R. N. Kirkwood, C. W. Ernst, P. S. Weber, N. P. Taylor, and N. L. Trottier. 2011. Transcript abundance of amino acid transporters, β-casein and α-lactalbumin in mammary tissue of peri-parturient, lactating and post-weaned sows. J. Dairy Sci. 94:3467-3476.
23. Mateo, R. D., G. Wu, H. K. Moon, J. A. Carroll, and S. W. Kim. 2008. Effects of dietary arginine supplementation during gestation and lactation on the performance of lactating primiparous sows and nursing piglets. J. Anim. Sci. 86:827-835.
24. Meininger, C.J., and G. Wu. 2002. Regulation of endothelial cell proliferation by nitric oxide. Methods Enzymol. 352:280-295.
25. Mikeska, T., and A. Dobrovic. 2009. Validation of a primer optimisation matrix to improve the performance of reverse transcription - quantitative real-time PCR assays. BMC Res. Notes 2:112-117.
26. Nelson, D.L., and M.M. Cox. 2008. Amino acid oxidation and the production of urea. Pag. 679 in Principles of Biochemistry, ed. Freeman, New York, NY.
27. Nielsen, T. T., N. L. Trottier, H. H. Stein, C. Bellaver, and R. A. Easter. 2002. The effect of litter size and day of lactation on amino acid uptake by the porcine mammary gland. J. Anim. Sci. 80:2402-2411.
28. Noblet, J., and M. Etienne. 1989. Estimation of sow milk nutrient output. J. Anim. Sci. 67:3352-3359.
29. NRC. 1998. Nutrient Requirements of Swine. 10th rev. ed. Natl. Acad. Press, Washington, DC.
30. NRC. 2012. Nutrient Requirements of Swine. 11th rev. ed. Natl. Acad. Press, Washington, DC.
31. O'Connor, P. M. J., S. R. Kimball, and A. Suryawan. 2003. Regulation of translation initiation by insulin and amino acids in skeletal muscle of neonatal pigs. Am. J. Physiol. 285:E40-E53.
32. Otto, E. R., M. Yokoyama, P. K. Ku, N. K. Ames, and N. L. Trottier. 2003. Nitrogen balance and ileal amino acid digestibility in growing pigs fed diets reduced in protein concentration. J. Anim. Sci. 81:1743-1753.
33. Palacín, M., R. Estevez, J. Bertran, and A. Zorzano. 1998. Molecular biology of mammalian AA transporters. Physiol. Rev. 78:969-1054.
34. Pérez-Laspiur, J. P., J. L. Burton, P. S. D. Weber, R. N. Kirkwood, and N. L. Trottier. 2004. Short communication: AA transporters in porcine mammary gland during lactation. J. Dairy Sci. 87:3235-3237.
35. Pérez-Laspiur, J. P., J. L. Burton, P. S. D. Weber, J. Moore, R. N. Kirkwood, and N. L. Trottier. 2009. Dietary protein intake and stage of lactation differentially modulate AA transporter mRNA abundance in porcine mammary tissue. J. Nutr. 139:1677-1684.
36. Richert, B. T., M. D. Tokach, R. D. Goodband, J. L. Nelssen, R. G. Campbell, and S. Kershaw. 1997. The effect of dietary lysine and valine fed during lactation on sow and litter performance. J. Anim. Sci. 75:1853-1860.
37. Satsu, H., H. Watanabe, S. Arai, and M. Shimizu. 1998. System B+-mediated regulation of lysine transport in Caco-2 human intestinal cells. Amino Acids 14:379-384.
38. Shennan, D. B., S. A. McNeillie, E. A. Jamieson, and D. T. Calvert.1994. Lysine transport in lactating rat mammary tissue: Evidence for an interaction between cationic and neutral amino acids. Acta Physiol. Scand. 151:461-466.
39. Shennan, D. B., I. D. Millar, and D. T. Calvert. 1997. Mammary-tissue amino acid transport systems. Proc. Nutr. Soc. 56:177-191.
40. Shennan, D. B., and M. Peaker. 2000. Transport of milk constituents by the mammary gland. Physiol. Rev. 80:925-951.
41. 0,+. J. Biol. Chem. 274:23740-23745.
42. Touchette, K. J., G. L. Allee, M. D. Newcomb, and R. D. Boyd. 1998. The lysine requirement of lactating primiparous sows. J. Anim. Sci. 76:1091-1097.
43. Tramontana, S., M. Bionaz, A. Sharma, D. E. Graugnard, E. A. Cutler, P. Ajmone-Marsan, W. L. Hurley, and J. J. Loor. 2008. Internal controls for quantitative polymerase chain reaction of swine mammary glands during pregnancy and lactation. J. Dairy Sci. 91:3057-3066.
44. Trottier, N. L., C. F. Shipley, and R. A. Easter. 1997. Plasma AA uptake by the mammary gland of the lactating sow. J. Anim. Sci. 75:1266-1278.
45. Vandesompele, J., K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe, and F. Speleman. 2002. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3:research0034- research0034.11.
46. Wu, G., F. W. Bazer, R. C. Burghardt, G. A. Johnson, S. W. Kim, D. A. Knabe, P. Li, X. L. Li, J. R. McKnight, M. C. Satterfield, and T. E. Spencer. 2011. Proline and hydroxyproline metabolism: Implications for animal and human nutrition. Amino Acids 40:1053-1063.
47. Wu, G., and C. J. Meininger. 2008. Analysis of citrulline, arginine, and methylarginines using high-performance liquid chromatography. Methods Enzymol. 440:177-189.
48. Wu, G., and S. M. Morris. 1998. Arginine metabolism: Nitric oxide and beyond. Biochem. J. 336:1-17.
49. Yang, H., J. E. Pettigrew, L. J. Johnston, G. C. Shurson, J. E. Wheaton, M. E. White, Y. Koketsu, A. F. Sower and J. A. Rathmacher. 2000. Effects of dietary Lys intake during lactation on blood metabolites, hormones, and reproductive performance in primiparous sows. J. Anim. Sci. 78:1001-1009.
50. Yuan, J. S., A. Reed, F. Chen, and C. N. Stewart. 2006. Statistical analysis of real-time PCR data. BMC Bioinformatics 7:85-97.