Removal of N-alkyl modifications from N2-ALKYLGUANINE and N 4-alkylcytosine in DNA by the adaptive response protein alkb

Chemical Research in Toxicology

Volumn 26, Issue 8, 2013, Pages 1182-1187

  Li, Deyu ^a,b   Fedeles, Bogdan I ^a,b   Shrivastav, Nidhi ^a,b,d   Delaney, James C ^a,b,e   Yang, Xuedong ^a,b,f   Wong, Cintyu ^a,g   Drennan, Catherine L ^a,b,c   Essigmann, John M ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF MONTANA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d MCKINSEY AND COMPANY   (United States)

^e VISTERRA INC   (United States)

^f TIANJIN UNIVERSITY   (China)

^g JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKB PROTEIN; ALKYL GROUP; CYTOSINE DERIVATIVE; DNA; DNA BASE; DOUBLE STRANDED DNA; GUANINE DERIVATIVE; MEMBRANE PROTEIN; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BIOCHEMICAL COMPOSITION; CHEMICAL MODIFICATION; CONTROLLED STUDY; DNA ADDUCT; ELECTROSPRAY MASS SPECTROMETRY; IN VITRO STUDY; TIME OF FLIGHT MASS SPECTROMETRY;

ALKYLATION; BASE PAIRING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSINE; DNA ADDUCTS; DNA, SINGLE-STRANDED; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GUANINE; MIXED FUNCTION OXYGENASES; OLIGONUCLEOTIDES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84882669451     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx400096m     Document Type: Article

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