Elimination of Von Hippel-Lindau Function Perturbs Pancreas Endocrine Homeostasis in Mice

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Puri, Sapna ^a   García Núñez, Alejandro ^b   Hebrok, Matthias ^a   Cano, David A ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSULIN; VON HIPPEL LINDAU PROTEIN; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1; VHLH PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; COHORT ANALYSIS; CONTROLLED STUDY; EMBRYO DEVELOPMENT; EPITHELIUM; FEMALE; GENE; GENE INACTIVATION; GLUCAGON RELEASE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HYPOGLYCEMIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INSULIN SENSITIVITY; MALE; MOUSE; NONHUMAN; PANCREAS; PANCREAS ISLET CELL; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SURVIVAL RATE; VHLH GENE; ANIMAL; ANIMAL EMBRYO; ANOXIA; CELL CULTURE; ENDOCRINE SYSTEM; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; KNOCKOUT MOUSE; METABOLISM; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREATIC POLYPEPTIDE SECRETING CELL; PATHOLOGY; SOMATOSTATIN CELL;

ANIMALS; ANOXIA; CELLS, CULTURED; EMBRYO, MAMMALIAN; ENDOCRINE SYSTEM; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCOSE; HOMEOSTASIS; HYPOXIA-INDUCIBLE FACTOR 1; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, KNOCKOUT; PANCREATIC POLYPEPTIDE-SECRETING CELLS; SIGNAL TRANSDUCTION; SOMATOSTATIN-SECRETING CELLS; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84882632325     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072213     Document Type: Article

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