-
2
-
-
0034677631
-
PIP2 and PIP3: Complex roles at the cell surface
-
Czech MP (2000) PIP2 and PIP3: complex roles at the cell surface. Cell 100:603-606
-
(2000)
Cell
, vol.100
, pp. 603-606
-
-
Czech, M.P.1
-
3
-
-
0035339289
-
Cellular signalling: Stressing the importance of PIP3
-
Hinchliffe KA (2001) Cellular signalling: stressing the importance of PIP3. Curr Biol 11:R371-R3373
-
(2001)
Curr Biol
, vol.11
-
-
Hinchliffe, K.A.1
-
4
-
-
42949124488
-
Comprehensive identification of PIP3-regulated PH domains from C. Elegans to H. Sapiens by model prediction and live imaging
-
Park WS, Heo WD, Whalen JH, O'Rourke NA, Bryan HM, Meyer T, Teruel MN (2008) Comprehensive identification of PIP3-regulated PH domains from C. elegans to H. sapiens by model prediction and live imaging. Mol Cell 30:381-392
-
(2008)
Mol Cell
, vol.30
, pp. 381-392
-
-
Park, W.S.1
Heo, W.D.2
Whalen, J.H.3
O'Rourke, N.A.4
Bryan, H.M.5
Meyer, T.6
Teruel, M.N.7
-
5
-
-
27844469655
-
Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3, 4, 5)P3 suggest their interaction with protein binding partners
-
Várnai P, Bondeva T, Tamás P, Tóth B, Buday L, Hunyady L, Balla T (2005) Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3, 4, 5)P3 suggest their interaction with protein binding partners. J Cell Sci 118:4879-4888
-
(2005)
J Cell Sci
, vol.118
, pp. 4879-4888
-
-
Várnai, P.1
Bondeva, T.2
Tamás, P.3
Tóth, B.4
Buday, L.5
Hunyady, L.6
Balla, T.7
-
6
-
-
0032053708
-
The synthesis and cellular roles of phosphati-dylinositol-4, 5-bisphosphate
-
Toker A (1998) The synthesis and cellular roles of phosphati-dylinositol- 4, 5-bisphosphate. Curr Opin Cell Biol 10:254-261
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 254-261
-
-
Toker, A.1
-
7
-
-
33747072874
-
Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN
-
Taniguchi CM, Tran TT, Kondo T et al (2006) Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN. Proc Natl Acad Sci USA 103: 12093-12097
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12093-12097
-
-
Taniguchi, C.M.1
Tran, T.T.2
Kondo, T.3
-
8
-
-
0036231778
-
Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice
-
Butler M, McKay RA, Popoff IJ et al (2002) Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice. Diabetes 51:1028-1034
-
(2002)
Diabetes
, vol.51
, pp. 1028-1034
-
-
Butler, M.1
McKay, R.A.2
Popoff, I.J.3
-
9
-
-
17844371042
-
Regulation of phos-phoinositide metabolism, AKT phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes
-
Ono H, Katagiri H, Funaki M et al (2001) Regulation of phos-phoinositide metabolism, AKT phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes. Mol Endocrinol 15: 1411-1422
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1411-1422
-
-
Ono, H.1
Katagiri, H.2
Funaki, M.3
-
10
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414:799-806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
11
-
-
81155132233
-
Hydrogen sulfide and L-cysteine increase phosphatidylinositol-3, 4, 5-trisphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kinase (AKT)/protein kinase Cf/k (PKCf/k) in 3T3L1 adipocytes
-
Manna P, Jain SK (2011) Hydrogen sulfide and L-cysteine increase phosphatidylinositol-3, 4, 5-trisphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kinase (AKT)/protein kinase Cf/k (PKCf/k) in 3T3L1 adipocytes. J Biol Chem 286:39848-39859
-
(2011)
J Biol Chem
, vol.286
, pp. 39848-39859
-
-
Manna, P.1
Jain, S.K.2
-
12
-
-
0028970171
-
Decreased erythrocyte membrane fluidity in poorly controlled IDDM. Influence of ketone bodies
-
Candiloros H, Muller S, Zeghari N, Donner M, Drouin P, Ziegler O (1995) Decreased erythrocyte membrane fluidity in poorly controlled IDDM. Influence of ketone bodies. Diabetes Care 18: 549-551
-
(1995)
Diabetes Care
, vol.18
, pp. 549-551
-
-
Candiloros, H.1
Muller, S.2
Zeghari, N.3
Donner, M.4
Drouin, P.5
Ziegler, O.6
-
13
-
-
78751664582
-
Novel use of fluorescent glucose analogues to identify a new class of triazine-based insulin mimetics possessing useful secondary effects
-
Jung DW, Ha HH, Zheng X, Chang YT, Williams DR (2011) Novel use of fluorescent glucose analogues to identify a new class of triazine-based insulin mimetics possessing useful secondary effects. Mol Biosyst 7:346-358
-
(2011)
Mol Biosyst
, vol.7
, pp. 346-358
-
-
Jung, D.W.1
Ha, H.H.2
Zheng, X.3
Chang, Y.T.4
Williams, D.R.5
-
14
-
-
80355124190
-
Quantitative measurement of GLUT4 translocation to the plasma membrane by flow cytometry
-
Koshy S, Alizadeh P, Timchenko LT, Beeton C (2010) Quantitative measurement of GLUT4 translocation to the plasma membrane by flow cytometry. J Vis Exp 45:e2429
-
(2010)
J Vis Exp
, vol.45
-
-
Koshy, S.1
Alizadeh, P.2
Timchenko, L.T.3
Beeton, C.4
-
15
-
-
79551470306
-
Oxidative stress, insulin signaling, and diabetes
-
Rains JL, Jain SK (2011) Oxidative stress, insulin signaling, and diabetes. Free Radic Biol Med 50:567-575
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 567-575
-
-
Rains, J.L.1
Jain, S.K.2
-
16
-
-
34548601740
-
The physiology of phosphoinositides
-
Sasaki T, Sasaki J, Sakai T, Takasuga S, Suzuki A (2007) The physiology of phosphoinositides. Biol Pharm Bull 30:1599-1604
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 1599-1604
-
-
Sasaki, T.1
Sasaki, J.2
Sakai, T.3
Takasuga, S.4
Suzuki, A.5
-
17
-
-
0033695810
-
Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-lambda on insulin-stimulated glucose transport in L6 myotu-bes
-
Bandyopadhyay G, Kanoh Y, Sajan MP, Standaert ML, Farese RV (2000) Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-lambda on insulin-stimulated glucose transport in L6 myotu-bes. Endocrinology 141:4120-4127
-
(2000)
Endocrinology
, vol.141
, pp. 4120-4127
-
-
Bandyopadhyay, G.1
Kanoh, Y.2
Sajan, M.P.3
Standaert, M.L.4
Farese, R.V.5
-
18
-
-
0030812546
-
Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes
-
Bandyopadhyay G, Standaert ML, Galloway L, Moscat J, Farese RV (1997) Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. Endocrinology 138:4721-4731
-
(1997)
Endocrinology
, vol.138
, pp. 4721-4731
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Galloway, L.3
Moscat, J.4
Farese, R.V.5
-
19
-
-
0031038052
-
Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport
-
Bandyopadhyay G, Standaert ML, Zhao L et al (1997) Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport. J Biol Chem 272:2551-2558
-
(1997)
J Biol Chem
, vol.272
, pp. 2551-2558
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Zhao, L.3
-
20
-
-
0031724590
-
Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes
-
Kotani K, Ogawa W, Matsumoto M et al (1998) Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes. Mol Cell Biol 18:6971-6982
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6971-6982
-
-
Kotani, K.1
Ogawa, W.2
Matsumoto, M.3
-
21
-
-
0036288402
-
Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states
-
Farese RV (2002) Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states. Am J Physiol Endocrinol Metab 283:E1-E11
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
-
-
Farese, R.V.1
-
22
-
-
0029849743
-
Structure, function, and regulation of the mammalian facilitative glucose transporter gene family
-
Olson AL, Pessin JE (1996) Structure, function, and regulation of the mammalian facilitative glucose transporter gene family. Annu Rev Nutr 16:235-256
-
(1996)
Annu Rev Nutr
, vol.16
, pp. 235-256
-
-
Olson, A.L.1
Pessin, J.E.2
-
23
-
-
0032080120
-
Membrane-permeant esters of phosphatidylin-ositol-3, 4, 5-trisphosphate
-
Jiang T, Sweeney G, Rudolf MT, Klip A, Traynor-Kaplan A, Tsien RY (1998) Membrane-permeant esters of phosphatidylin-ositol-3, 4, 5-trisphosphate. J Biol Chem 273:11017-11024
-
(1998)
J Biol Chem
, vol.273
, pp. 11017-11024
-
-
Jiang, T.1
Sweeney, G.2
Rudolf, M.T.3
Klip, A.4
Traynor-Kaplan, A.5
Tsien, R.Y.6
-
24
-
-
33746973238
-
PI-4, 5-P2 stimulates glucose transport activity of GLUT4 in the plasma membrane of 3T3-L1 adipocytes
-
Funaki M, DiFransico L, Janmey PA (2006) PI-4, 5-P2 stimulates glucose transport activity of GLUT4 in the plasma membrane of 3T3-L1 adipocytes. Biochim Biophys Acta 1763:889-899
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 889-899
-
-
Funaki, M.1
Difransico, L.2
Janmey, P.A.3
-
25
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S et al (2002) Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8:1288-1295
-
(2002)
Nat Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
-
26
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM et al (2001) The hormone resistin links obesity to diabetes. Nature 409:307-312
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
Brown, E.J.4
Banerjee, R.R.5
Wright, C.M.6
-
27
-
-
0037341813
-
Molecular mechanisms mediating inflammation in vascular disease: Special reference to monocyte chemo-attractant protein-1
-
Egashira K (2003) Molecular mechanisms mediating inflammation in vascular disease: special reference to monocyte chemo-attractant protein-1. Hypertension 41:834-841
-
(2003)
Hypertension
, vol.41
, pp. 834-841
-
-
Egashira, K.1
-
28
-
-
0042093782
-
Activation of protein kinase C-zeta by insulin and phosphatidylinositol- 3, 4, 5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: Amelioration by rosiglitazone and exercise
-
Beeson M, Sajan MP, Dizon M, Grebenev D, Gomez-Daspet J, Miura A et al (2003) Activation of protein kinase C-zeta by insulin and phosphatidylinositol- 3, 4, 5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise. Diabetes 52:1926-1934
-
(2003)
Diabetes
, vol.52
, pp. 1926-1934
-
-
Beeson, M.1
Sajan, M.P.2
Dizon, M.3
Grebenev, D.4
Gomez-Daspet, J.5
Miura, A.6
-
29
-
-
0042093781
-
Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: Reversal with weight reduction
-
Kim YB, Kotani K, Ciaraldi TP, Henry RR, Kahn BB (2003) Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction. Diabetes 52:1935-1942
-
(2003)
Diabetes
, vol.52
, pp. 1935-1942
-
-
Kim, Y.B.1
Kotani, K.2
Ciaraldi, T.P.3
Henry, R.R.4
Kahn, B.B.5
-
30
-
-
84882456737
-
Atypical protein kinase C in cell motility
-
in press
-
Xiao H, Liu M (2012) Atypical protein kinase C in cell motility. Cell Mol Life Sci (in press)
-
(2012)
Cell Mol Life Sci
-
-
Xiao, H.1
Liu, M.2
-
31
-
-
0642376906
-
Protein kinase Czeta (PKCzeta): Activation mechanisms and cellular functions
-
Hirai T, Chida K (2003) Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions. J Biochem 133:1-7
-
(2003)
J Biochem
, vol.133
, pp. 1-7
-
-
Hirai, T.1
Chida, K.2
-
32
-
-
5044250556
-
Defective activation of protein kinase C-z in muscle by insulin and phosphatidylinositol-3, 4, 5, -(PO(4))(3) in obesity and polycystic ovary syndrome
-
Beeson M, Sajan MP, Daspet JG, Luna V, Dizon M, Grebenev D et al (2004) Defective activation of protein kinase C-z in muscle by insulin and phosphatidylinositol-3, 4, 5, -(PO(4))(3) in obesity and polycystic ovary syndrome. Metab Syndr Relat Disord 2:49-56
-
(2004)
Metab Syndr Relat Disord
, vol.2
, pp. 49-56
-
-
Beeson, M.1
Sajan, M.P.2
Daspet, J.G.3
Luna, V.4
Dizon, M.5
Grebenev, D.6
-
33
-
-
0036227755
-
Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylin-ositol- 3-kinase activation, and impaired atypical protein kinase C (f/k) activation in myotubes from obese patients with impaired glucose tolerance
-
Vollenweider P, Menard B, Nicod P (2002) Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylin-ositol- 3-kinase activation, and impaired atypical protein kinase C (f/k) activation in myotubes from obese patients with impaired glucose tolerance. Diabetes 15:1052-1059
-
(2002)
Diabetes
, vol.15
, pp. 1052-1059
-
-
Vollenweider, P.1
Menard, B.2
Nicod, P.3
-
34
-
-
31844437335
-
Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3, 4, 5-(PO4)3 in muscle of diabetic subjects
-
Luna V, Casauban L, Sajan MP, Gomez-Daspet J, Powe JL, Miura A et al (2006) Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3, 4, 5-(PO4)3 in muscle of diabetic subjects. Diabetologia 49:375-382
-
(2006)
Diabetologia
, vol.49
, pp. 375-382
-
-
Luna, V.1
Casauban, L.2
Sajan, M.P.3
Gomez-Daspet, J.4
Powe, J.L.5
Miura, A.6
|