Triptolide induces apoptosis of PMA-treated THP-1 cells through activation of caspases, inhibition of NF-κB and activation of MAPKs

International Journal of Oncology

Volumn 43, Issue 4, 2013, Pages 1169-1175

  Park, Seung Won ^a   Kim, Young Il ^b,c  

^a Catholic University of Daegu   (South Korea)

^b Kyung Hee University College of Medicine   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

Apoptosis; Caspase; Mitogen activated protein kinase; Nuclear factor B; THP 1 cells; Triptolide

Indexed keywords

ANTINEOPLASTIC AGENT; BETA ACTIN; CASPASE; CASPASE 3; CASPASE 9; CYCLIN D1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P27; SURVIVIN; TRIPTOLIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL GROWTH; CELL POPULATION; CELL PROLIFERATION; CELL STRAIN THP 1; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MONOCYTIC LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; CASPASE INHIBITORS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; DITERPENES; EPOXY COMPOUNDS; HUMANS; I-KAPPA B PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHENANTHRENES; PHOSPHORYLCHOLINE; POLYMETHACRYLIC ACIDS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84882431139     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2033     Document Type: Article

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