Emerging and existing mechanisms co-operate in generating diverse β-lactam resistance phenotypes in geographically dispersed and genetically disparate Pseudomonas aeruginosa strains

Journal of Global Antimicrobial Resistance

Volumn 1, Issue 3, 2013, Pages 135-142

  Martinez, Elena ^a   Pérez, Javier Escobar ^b   Márquez, Carolina ^c   Vilacoba, Elisabet ^d   Centrón, Daniela ^d   Leal, Aura L ^e   Saavedra, Carlos ^e   Saavedra, Sandra Y ^e   Tovar, Catalina ^f   Vanegas, Natasha ^a,b   Stokes, H W ^a  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b UNIVERSIDAD EL BOSQUE   (Colombia)

^c Inst de Investigaciones Pesqueras   (Uruguay)

^d Universidad de Buenos Aires Consejo Nacional de Investigaciones Cientificas y Tecnologicas ^*  (Argentina)

^e UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^f UNIVERSIDAD DEL SINÚ   (Colombia)

Author keywords

Antibiotic resistance; Carbapenem; Class 1 integron; Efflux pumps; Genomic island IS26; Pseudomonas aeruginosa

Indexed keywords

ANTIBIOTIC AGENT; BETA LACTAMASE AMPC; CARBAPENEM DERIVATIVE;

ANTIBIOTIC RESISTANCE; ARGENTINA; ARTICLE; AUSTRALIA; BACTERIAL STRAIN; BACTERIUM CULTURE; CHROMOSOME; COLOMBIA; DNA TRANSPOSITION; EFFUSION; GENE EXPRESSION; GENE INSERTION SEQUENCE; GEOGRAPHIC DISTRIBUTION; HORIZONTAL GENE TRANSFER; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; QUANTITATIVE ANALYSIS; URUGUAY;

EID: 84882365774     PISSN: 22137165     EISSN: 22137173     Source Type: Journal    
DOI: 10.1016/j.jgar.2013.03.013     Document Type: Article

References (33)

1. R.N. Jones, J.T. Kirby, M.L. Beach, D.J. Biedenbach, and M.A. Pfaller Geographic variations in activity of broad-spectrum β-lactams against Pseudomonas aeruginosa: summary of the worldwide SENTRY Antimicrobial Surveillance Program (1997-2000) Diagnostic Microbiology and Infectious Disease 43 2002 239 243
2. P.D. Lister, D.J. Wolter, and N.D. Hanson Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms Clinical Microbiology Reviews 22 2009 582 610
3. N. Masuda, E. Sakagawa, S. Ohya, N. Gotoh, H. Tsujimoto, and T. Nishino Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-OprM efflux pumps in Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy 44 2000 3322 3327
4. T. Kohler, M. Michea-Hamzehpour, U. Henze, N. Gotoh, L.K. Curty, and J.C. Pechere Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa Molecular Microbiology 23 1997 345 354
5. K. Poole, N. Gotoh, H. Tsujimoto, Q. Zhao, A. Wada, and T. Yamasaki Overexpression of the mexC-mexD-oprJ efflux operon in nfxB-type multidrug-resistant strains of Pseudomonas aeruginosa Molecular Microbiology 21 1996 713 724
6. P.D. Lister, V.M. Gardner, and C.C. Sanders Clavulanate induces expression of the Pseudomonas aeruginosa AmpC cephalosporinase at physiologically relevant concentrations and antagonizes the antibacterial activity of ticarcillin Antimicrobial Agents and Chemotherapy 43 1999 882 889
7. C. Juan, M.D. Maciá, O. Gutiérrez, C. Vidal, J.L. Pérez, and A. Oliver Molecular mechanisms of β-lactam resistance mediated by AmpC hyperproduction in Pseudomonas aeruginosa clinical strains Antimicrobial Agents and Chemotherapy 49 2005 4733 4738
8. O. Gutiérrez, C. Juan, E. Cercenado, F. Navarro, E. Bouza, and P. Coll Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals Antimicrobial Agents and Chemotherapy 51 2007 4329 4335
9. A.A. Ocampo-Sosa, G. Cabot, C. Rodríguez, E. Roman, F. Tubau, and M.D. Macia Spanish Network for Research in Infectious Diseases (REIPI). Alterations of OprD in carbapenem-intermediate and -susceptible strains of Pseudomonas aeruginosa isolated from bacteremia in a Spanish multicenter study Antimicrobial Agents and Chemotherapy 56 2012 1703 1713
10. E. Martinez, C. Marquez, A. Ingold, J. Merlino, S.P. Djordjevic, and H.W. Stokes Diverse mobilized class 1 integrons are common in the chromosome of pathogenic Pseudomonas aeruginosa clinical isolates Antimicrobial Agents and Chemotherapy 56 2012 2169 2172
11. P.A. Bradford Extended-spectrum β-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat Clinical Microbiology Reviews 14 2001 933 951
12. P.B. Rainey, H.J. Beaumont, G.C. Ferguson, J. Gallie, C. Kost, and E. Libby The evolutionary emergence of stochastic phenotype switching in bacteria Microbial Cell Factories 10 SUPPL.. 1 2011 S14
13. C.G. Giske, B. Libisch, C. Colinon, E. Scoulica, L. Pagani, and M. Füzi Establishing clonal relationships between VIM-1-like metallo-β-lactamase-producing Pseudomonas aeruginosa strains from four European countries by multilocus sequence typing Journal of Clinical Microbiology 44 2006 4309 4315
14. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: twentieth informational SUPPL.ement. Document M100-S20. Wayne, PA: CLSI; 2010.
15. C. Márquez, M. Labbate, C. Raymondo, J. Fernández, A.M. Gestal, and M. Holley Urinary tract infections in a South American population: dynamic spread of class 1 integrons and multidrug resistance by homologous and site-specific recombination Journal of Clinical Microbiology 46 2008 3417 3425
16. T. Betteridge, S.R. Partridge, J.R. Iredell, and H.W. Stokes Genetic context and structural diversity of class 1 integrons from human commensal bacteria in a hospital intensive care unit Antimicrobial Agents and Chemotherapy 55 2011 3939 3943
17. A.J. Holmes, M.R. Gillings, B.S. Nield, B.C. Mabbutt, K.M.H. Nevalainen, and H.W. Stokes The gene cassette metagenome is a basic resource for bacterial genome evolution Environmental Microbiology 5 2003 383 394
18. A. Carattoli, A. Bertini, L. Villa, V. Falbo, K.L. Hopkins, and E.J. Threlfall Identification of plasmids by PCR-based replicon typing Journal of Microbiological Methods 63 2005 219 228
19. D. Xavier, R. Picao, R. Girardello, L. Fehlberg, and A. Gales Efflux pumps expression and its association with porin down-regulation and β-lactamase production among Pseudomonas aeruginosa causing bloodstream infections in Brazil BMC Microbiology 10 2010 217
20. -ΔΔCT method Methods 25 2001 402 408
21. G. Cabot, A.A. Ocampo-Sosa, F. Tubau, M.D. Macia, C. Rodríguez, and B. Moya Spanish Network for Research in Infectious Diseases (REIPI). Overexpression of AmpC and efflux pumps in Pseudomonas aeruginosa isolates from bloodstream infections: prevalence and impact on resistance in a Spanish multicenter study Antimicrobial Agents and Chemotherapy 55 2011 1906 1911
22. VIM-1 gene associated with different Tn402 variants, mercury transposons, and conjugative plasmids in Enterobacteriaceae and Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy 54 2010 320 327
23. T. Miyoshi-Akiyama, T. Kuwahara, T. Tada, T. Kitao, and T. Kirikae Complete genome sequence of highly multidrug-resistant Pseudomonas aeruginosa NCGM2.S1, a representative strain of a cluster endemic to Japan Journal of Bacteriology 193 2011 7010
24. A.K. Cain, X. Liu, S.P. Djordjevic, and R.M. Hall Transposons related to Tn1696 in IncHI2 plasmids in multiply antibiotic resistant Salmonella enterica serovar Typhimurium from Australian animals Microbial Drug Resistance 16 2010 197 202
25. S.E. Luria, and M. Delbruck Mutations of bacteria from virus sensitivity to virus resistance Genetics 28 1943 491 511
26. H. Li, Y.F. Luo, B.J. Williams, T.S. Blackwell, and C.M. Xie Structure and function of OprD protein in Pseudomonas aeruginosa: from antibiotic resistance to novel therapies International Journal of Medical Microbiology 302 2012 63 68
27. G. Cabot, A.A. Ocampo-Sosa, M.A. Domínguez, J.F. Gago, C. Juan, and F. Tubau Spanish Network for Research in Infectious Diseases (REIPI). Genetic markers of widespread extensively drug-resistant Pseudomonas aeruginosa high-risk clones Antimicrobial Agents and Chemotherapy 56 2012 6349 6357
28. B. Georges, J.M. Conil, A. Dubouix, M. Archambaud, E. Bonnet, and S. Saivin Risk of emergence of Pseudomonas aeruginosa resistance to β-lactam antibiotics in intensive care units Critical Care Medicine 34 2006 1636 1641
29. H.W. Stokes, E. Martinez, P. Roy Chowdhury, and S. Djordjevic Class 1 integron-associated spread of resistance regions in Pseudomonas aeruginosa: plasmid or chromosomal platforms? Journal of Antimicrobial Chemotherapy 67 2012 1799 1800
30. I.K. Bae, Y-N. Lee, S.H. Jeong, S.G. Hong, J.H. Lee, and S.H. Lee Genetic and biochemical characterization of GES-5, an extended-spectrum class A β-lactamase from Klebsiella pneumoniae Diagnostic Microbiology and Infectious Disease 58 2007 465 468
31. F. Danel, L.M. Hall, B. Duke, D. Gur, and D.M. Livermore OXA-17 a further extended-spectrum variant of OXA-10 β-lactamase, isolated from Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy 43 1999 1362 1366
32. J. Walther-Rasmussen, and N. Høiby OXA-type carbapenemases Journal of Antimicrobial Chemotherapy 57 2006 373 383
33. Y. Morita, C. Gilmour, D. Metcalf, and K. Poole Translational control of the antibiotic inducibility of the PA5471 gene required for mexXY multidrug efflux gene expression in Pseudomonas aeruginosa Journal of Bacteriology 191 2009 4966 4975