Micro/Nano-particle deposition in the airway of a 6-year-old child from nostril to the third generation

American Society of Mechanical Engineers, Fluids Engineering Division (Publication) FEDSM

Volumn 1, Issue PARTS A AND B, 2012, Pages 831-837

  Keshavarzian, Erfan ^a   Ghalati, Pejman Farhadi ^a   Abouali, Omid ^a   Ahmadi, Goodarz ^b   Bagheri, Mohammad Hadi ^c  

^a SHIRAZ UNIVERSITY   (Iran)

^b Clarkson University   (United States)

^c SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTERIZED TOMOGRAPHY; DEPOSITION RATES; HEAT TRANSFER; MICROCHANNELS; RESPIRATORY MECHANICS;

AIRWAY MODELING; BRONCHIAL AIRWAYS; CT-SCAN IMAGES; HIGH RESOLUTION CT; MICRO PARTICLES; MICRO/NANO PARTICLE; NASAL CAVITY; PARTICLES DEPOSITIONS; THIRD GENERATION; UPPER AIRWAY;

NANOPARTICLES;

EID: 84882342325     PISSN: 08888116     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1115/FEDSM2012-72366     Document Type: Conference Paper

References (23)

1. J.H. Wildhaber, F.H. Sennhauser, P.L.P. Brand, Respiratory Diseases in Infants and Children.
2. S. Zachow, A. Steinmann, T. Hildebrandt, R. Weber, W. Heppt, CFD simulation of nasal airflow: towards treatment planning for functional rhinosurgery, Int. Congr. Ser. (2006) 165-167.
3. J. Wen, K. Inthavong, J.Y. Tu, S. Wang, Numerical simulations for detailed airflow dynamics in a human nasal cavity, Respir. Physiol. Neurobiol. (2008) 125-135.
4. P. Zamankhan, G. Ahmadi, Z. Wang, P.K. Hopke, Y.S. Cheng, W.C. Su, D. Leonard, Airflow and deposition of nanoparticle in a human nasal cavity, Aerosol Sci. Technol. 40 (2006) 463-476.
5. J. Xi, P.W. Longest, Numerical predictions of submicronmeter aerosol deposition in the nasal cavity using a novel drift flux approach, Int. J. Heat Mass Transfer 51 (2008) 5562-5577.
6. S. Wang, K. Inthavong, J. Wen, J.Y. Tu, C.L. Xue, Comparison of micron and nano-particle deposition patterns in a realistic human nasal cavity, Respir. Physiol. Neurobiol. 166 (2009) 142-151.
7. H. Moghadas, O. Abouali, A. Faramarzi, G. Ahmadi, Numerical investigation of septal deviation effect on deposition of nano/micro particles in human nasal passage, Respir. Physiol. Neurobiol. 177 (2011) 9-18.
8. I. Hahn, P.W. Scherer, M.M. Mozell, Velocity profiles measured for airflow through a large-scale model of the human nasal cavity, J. Appl. Physiol. 75 (1993) 2273-2287.
9. J.T. Kelly, A.K. Prasad, A.S. Wexler, Detailed flow patterns in the nasal cavity, J. Appl. Physiol. 89 (2000) 323-337.
10. D.J. Doorly, D.J. Taylor, R.C. Schroter, Mechanics of airflow in the human nasal airways, Respir. Physiol. Neurobiol. 163 (2008) 100-110.
11. J.T. Kelly, B. Asgharian, J.S. Kimbell, B.A. Wong, Particle deposition in human nasal airway replicas manufactured by different methods, part I: inertial regime particle, Aerosol Sci. Technol. 38 (2004) 1063-1071.
12. J.T. Kelly, B. Asgharian, J.S. Kimbell, B.A. Wong, Particle deposition in human nasal airway replicas manufactured by different methods, part II: ultrafine particles, Aerosol Sci. Technol. 38 (2004) 1072-1079.
13. Y. Wang, Y. Liu, X. Sun, Sh. Yu, F. Gao, Numerical analysis of respiratory flow patterns within human upper airway, Acta Mech. Sin. 25 (2009) 737-746.
14. G. Mylavarapu, Sh. Murugappan, M. Mihaescu, M. Kalra, S. Khosla, E. Gutmark, Validation of computational fluid dynamics methodology used for human upper airway flow simulations, J. Biomech. 42 (2009) 1553-1559.
15. P. FarhadiGhalati, E. Keshavarzian, O. Abouali, A. Faramarzi, J. Tu, A. Shakibafard, Numerical analysis of microand nano-particle deposition in realistic human upper airway, Computers in Biology and Medicine 42(2012), 39-49.
16. J. Storey-Bishoff, M. Noga, W.H. Finaly, Deposition of micrometer-sized aerosol particles in infant nasal airway replicas, Journal of Aerosol science 39 (2008) 1055-1065.
17. J. Xi, X. Si, J. Won Kim, A. Berlinski, Simulation of airflow and aerosol deposition in the nasal cavity of a 5-yearold child, J. Aerosol Sci. 42 (2011) 156-173.
18. H.Y. Luo, Y. Liu, X.L. Yang, Particle deposition in obstructed airways, Journal of Biomechanics 40 (2007) 3096-3104
19. X.L. Yang, Y. Liu, H.Y. Luo, Respiratory flow in obstructed airways, Journal of Biomechanics 39 (2006) 2743-2751
20. L. Golshahi, M.L. Noga, R.B. Thompson, W.H. Finlay, In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing, J. Aerosol Sci. doi:10.1016/j.jaerosci.2011.04.002.
21. R.F. Hounam, A. Black, M. Walsh, The deposition of aerosol particles in the nasopharyngeal region of the human respiratory tract, J. Aerosol Sci. 2 (1971) 47-61.
22. FLUENT Inc., FLUENT 6.3 User's Guide. Lebanon, New Hampshire, USA (2006).
23. GAMBIT 2.2, Modeling Guide, FLUENT Inc., Lebanon, New Hampshire, USA (2005).